| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I Murak. [Behavioral and neurochemical study on the mechanism of the anxiolytic effect of a selective serotonin reuptake inhibitor, a selective serotonin1A agonist and lithium carbonate]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 76. issue 2. 2001-06-21. PMID:11344903. |
the authors investigated the effects of citalopram [selective serotonin (5-ht) reuptake inhibitor; ssri] and mkc-242 (a selective 5-ht1a agonist) following treatment with subchronic lithium (p.o., 1 week) on the expression of conditioned freezing, an index of anxiety, and on extracellular 5-ht concentrations in the medial prefrontal cortex (mpfc). |
2001-06-21 |
2023-08-12 |
Not clear |
| J C Chen, K W Liang, E Y Huan. Differential effects of endomorphin-1 and -2 on amphetamine sensitization: neurochemical and behavioral aspects. Synapse (New York, N.Y.). vol 39. issue 3. 2001-05-10. PMID:11169772. |
in the same animals, endomorphins also caused decreases in the levels of serotonin and its metabolite, 5-hydroxyindoleacetic acid, in the medial prefrontal cortex. |
2001-05-10 |
2023-08-12 |
rat |
| J Ichikawa, H Ishii, S Bonaccorso, W L Fowler, I A O'Laughlin, H Y Meltze. 5-HT(2A) and D(2) receptor blockade increases cortical DA release via 5-HT(1A) receptor activation: a possible mechanism of atypical antipsychotic-induced cortical dopamine release. Journal of neurochemistry. vol 76. issue 5. 2001-04-05. PMID:11238736. |
the present study tested the hypothesis that clozapine, olanzapine, risperidone, and perhaps other atypical apds, increase dopamine release in rat medial prefrontal cortex (mpfc) via 5-ht(1a) receptor activation, as a result of the blockade of 5-ht(2a) and d(2) receptors. |
2001-04-05 |
2023-08-12 |
rat |
| S Hashimot. [Anxiolytic effects of serotonin reuptake inhibitors and their mechanism of action]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 75. issue 6. 2001-03-15. PMID:11193934. |
cfs elevated extracellular 5-ht levels in the medial prefrontal cortex, and this elevations of 5-ht level was followed by a resolution of the freezing. |
2001-03-15 |
2023-08-12 |
rat |
| E A Pehek, H G McFarlane, K Maguschak, B Price, C P Plut. M100,907, a selective 5-HT(2A) antagonist, attenuates dopamine release in the rat medial prefrontal cortex. Brain research. vol 888. issue 1. 2001-03-01. PMID:11146051. |
m100,907, a selective 5-ht(2a) antagonist, attenuates dopamine release in the rat medial prefrontal cortex. |
2001-03-01 |
2023-08-12 |
rat |
| E A Pehek, H G McFarlane, K Maguschak, B Price, C P Plut. M100,907, a selective 5-HT(2A) antagonist, attenuates dopamine release in the rat medial prefrontal cortex. Brain research. vol 888. issue 1. 2001-03-01. PMID:11146051. |
however, the specific role of 5-ht(2a) receptors localized within the medial prefrontal cortex (mpfc) is not known. |
2001-03-01 |
2023-08-12 |
rat |
| J Cartmell, C R Salhoff, K W Perry, J A Monn, D D Schoep. Dopamine and 5-HT turnover are increased by the mGlu2/3 receptor agonist LY379268 in rat medial prefrontal cortex, nucleus accumbens and striatum. Brain research. vol 887. issue 2. 2001-02-15. PMID:11134627. |
dopamine and 5-ht turnover are increased by the mglu2/3 receptor agonist ly379268 in rat medial prefrontal cortex, nucleus accumbens and striatum. |
2001-02-15 |
2023-08-12 |
rat |
| J Cartmell, C R Salhoff, K W Perry, J A Monn, D D Schoep. Dopamine and 5-HT turnover are increased by the mGlu2/3 receptor agonist LY379268 in rat medial prefrontal cortex, nucleus accumbens and striatum. Brain research. vol 887. issue 2. 2001-02-15. PMID:11134627. |
we have shown, using in vivo microdialysis sampling, that systemic administration of the selective group ii metabotropic (mglu) receptor agonist ly379268, like the atypical antipsychotic clozapine, increased extracellular levels of dopamine, dopamine metabolites dopac and hva, and the major 5-ht metabolite 5-hiaa, in rat medial prefrontal cortex (mpfc). |
2001-02-15 |
2023-08-12 |
rat |
| N Haddjeri, G Lucas, P Blie. Role of cholinergic and GABAergic systems in the feedback inhibition of dorsal raphe 5-HT neurons. Neuroreport. vol 11. issue 15. 2001-02-08. PMID:11059909. |
several observations indicate that 5-ht1a receptors found on a long neuronal feedback loop, originating from the medial prefrontal cortex, regulate 5-ht neuronal firing. |
2001-02-08 |
2023-08-12 |
rat |
| C A Heidbreder, I C Weiss, A M Domeney, C Pryce, J Homberg, G Hedou, J Feldon, M C Moran, P Nelso. Behavioral, neurochemical and endocrinological characterization of the early social isolation syndrome. Neuroscience. vol 100. issue 4. 2001-01-18. PMID:11036209. |
the results of the present study demonstrate that rearing rats in isolation (i) produces a syndrome of generalized locomotor hyperactivity; (ii) increases the startle response; (iii) impairs prepulse inhibition; (iv) tends to increase food hoarding behavior; (v) increases basal dopamine turnover in the amygdaloid complex; (vi) decreases basal dopamine turnover in the infralimbic part of the medial prefrontal cortex; and (vii) decreases basal turnover of serotonin in the nucleus accumbens. |
2001-01-18 |
2023-08-12 |
rat |
| J M Casanovas, O Berton, P Celada, F Artiga. In vivo actions of the selective 5-HT1A receptor agonist BAY x 3702 on serotonergic cell firing and release. Naunyn-Schmiedeberg's archives of pharmacology. vol 362. issue 3. 2001-01-05. PMID:10997727. |
in microdialysis experiments, bay x 3702 (10-100 microg/ kg s.c.) reduced dose-dependently the 5-ht output in the dorsal and median raphe (mnr) nucleus, dorsal hippocampus (dhpc) and medial prefrontal cortex (mpfc) in a regionally selective manner. |
2001-01-05 |
2023-08-12 |
rat |
| L I Perrotti, K D Beck, V N Luine, V Quiñone. Progesterone and cocaine administration affect serotonin in the medial prefrontal cortex of ovariectomized rats. Neuroscience letters. vol 291. issue 3. 2000-11-30. PMID:10984630. |
progesterone and cocaine administration affect serotonin in the medial prefrontal cortex of ovariectomized rats. |
2000-11-30 |
2023-08-12 |
rat |
| J C Gewirtz, G J Mare. Behavioral evidence for interactions between a hallucinogenic drug and group II metabotropic glutamate receptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 23. issue 5. 2000-11-21. PMID:11027922. |
recent electrophysiological studies in our laboratory have demonstrated a physiological interaction between 5-ht(2a) and metabotropic glutamate2/3 (mglu2/3) receptors in the medial prefrontal cortex. |
2000-11-21 |
2023-08-12 |
Not clear |
| J C Gewirtz, G J Mare. Behavioral evidence for interactions between a hallucinogenic drug and group II metabotropic glutamate receptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 23. issue 5. 2000-11-21. PMID:11027922. |
several behavioral studies have found that phenethylamine hallucinogens with partial agonist activity at 5-ht(2a) receptors induce head shakes when directly administered into the medial prefrontal cortex. |
2000-11-21 |
2023-08-12 |
Not clear |
| F M Benes, J B Taylor, M C Cunningha. Convergence and plasticity of monoaminergic systems in the medial prefrontal cortex during the postnatal period: implications for the development of psychopathology. Cerebral cortex (New York, N.Y. : 1991). vol 10. issue 10. 2000-10-25. PMID:11007552. |
a recent triple immunofluorescence study has demonstrated a convergence of serotonin and dopamine fibers onto both pyramidal cells and gabaergic interneurons in the rat medial prefrontal cortex (mpfcx). |
2000-10-25 |
2023-08-12 |
rat |
| T Kuroki, J Dai, H Y Meltzer, J Ichikaw. R(+)-8-OH-DPAT, a selective 5-HT(1A) receptor agonist, attenuated amphetamine-induced dopamine synthesis in rat striatum, but not nucleus accumbens or medial prefrontal cortex. Brain research. vol 872. issue 1-2. 2000-09-20. PMID:10924694. |
r(+)-8-oh-dpat, a selective 5-ht(1a) receptor agonist, attenuated amphetamine-induced dopamine synthesis in rat striatum, but not nucleus accumbens or medial prefrontal cortex. |
2000-09-20 |
2023-08-12 |
rat |
| S E Gartside, E Hajós-Korcsok, E Bagdy, L G Hársing, T Sharp, M Hajó. Neurochemical and electrophysiological studies on the functional significance of burst firing in serotonergic neurons. Neuroscience. vol 98. issue 2. 2000-08-18. PMID:10854760. |
secondly, we used in vivo microdialysis to monitor changes in endogenous extracellular 5-hydroxytryptamine in rat medial prefrontal cortex in response to electrical stimulation (3 hz for 10 min) of the dorsal raphe nucleus. |
2000-08-18 |
2023-08-12 |
rat |
| S E Gartside, E Hajós-Korcsok, E Bagdy, L G Hársing, T Sharp, M Hajó. Neurochemical and electrophysiological studies on the functional significance of burst firing in serotonergic neurons. Neuroscience. vol 98. issue 2. 2000-08-18. PMID:10854760. |
finally, we used in vivo extracellular recording to follow the response of postsynaptic neurons in the rat medial prefrontal cortex to 5-hydroxytryptamine released by dorsal raphe stimulation. |
2000-08-18 |
2023-08-12 |
rat |
| G Hedou, J Homberg, S Martin, K Wirth, J Feldon, C A Heidbrede. Effect of amphetamine on extracellular acetylcholine and monoamine levels in subterritories of the rat medial prefrontal cortex. European journal of pharmacology. vol 390. issue 1-2. 2000-05-11. PMID:10708716. |
the results demonstrate that basal levels of acetylcholine, choline, and serotonin were homogeneous within subregions of the medial prefrontal cortex. |
2000-05-11 |
2023-08-12 |
rat |
| G Hedou, J Homberg, S Martin, K Wirth, J Feldon, C A Heidbrede. Effect of amphetamine on extracellular acetylcholine and monoamine levels in subterritories of the rat medial prefrontal cortex. European journal of pharmacology. vol 390. issue 1-2. 2000-05-11. PMID:10708716. |
reverse microdialysis of amphetamine in both subareas of the medial prefrontal cortex produced a dose-dependent increase in norepinephrine and serotonin levels; the magnitude of this effect was similar in both subterritories of the medial prefrontal cortex. |
2000-05-11 |
2023-08-12 |
rat |