| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Takeshi Inoue, Takeshi Izumi, Xiao-Bai Li, Ji Zhong Huang, Yuji Kitaichi, Shin Nakagawa, Tsukasa Koyam. [Biological basis of anxiety disorders and serotonergic anxiolytics]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 24. issue 3. 2004-08-16. PMID:15291241. |
cfs increased serotonin neurotransmission in the medial prefrontal cortex and amygdala. |
2004-08-16 |
2023-08-12 |
Not clear |
| Takeshi Inoue, Takeshi Izumi, Xiao-Bai Li, Ji Zhong Huang, Yuji Kitaichi, Shin Nakagawa, Tsukasa Koyam. [Biological basis of anxiety disorders and serotonergic anxiolytics]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 24. issue 3. 2004-08-16. PMID:15291241. |
in vivo microdialysis studies showed that serotonin neurotransmission in the medial prefrontal cortex increased after recovery from the freezing behavior. |
2004-08-16 |
2023-08-12 |
Not clear |
| Kazuhiko Nakayama, Takashi Sakurai, Hisatoshi Kats. Mirtazapine increases dopamine release in prefrontal cortex by 5-HT1A receptor activation. Brain research bulletin. vol 63. issue 3. 2004-07-15. PMID:15145142. |
produced a dose-dependent increase in extracellular dopamine levels in the medial prefrontal cortex (mpfc) of freely moving rats without modifying those of 5-ht. |
2004-07-15 |
2023-08-12 |
rat |
| L Linnér, C Wiker, L Arborelius, M Schalling, T H Svensso. Selective noradrenaline reuptake inhibition enhances serotonergic neuronal activity and transmitter release in the rat forebrain. Journal of neural transmission (Vienna, Austria : 1996). vol 111. issue 2. 2004-05-19. PMID:14767716. |
also, in the medial prefrontal cortex reboxetine (3 mg/kg s.c.) enhanced, whereas citalopram (3 mg/kg s.c.) reduced, extracellular concentrations of serotonin measured by means of microdialysis in awake rats, using a low dose of citalopram (0,5 micro m) in the perfusion solution. |
2004-05-19 |
2023-08-12 |
rat |
| T Abekawa, M Honda, K Ito, T Koyam. Effects of NRA0045, a novel potent antagonist at dopamine D4, 5-HT2A, and alpha1 adrenaline receptors, and NRA0160, a selective D4 receptor antagonist, on phencyclidine-induced behavior and glutamate release in rats. Psychopharmacology. vol 169. issue 3-4. 2004-02-23. PMID:12898123. |
this study examined the effects of a novel thiazole derivative, nra0045 which potently antagonizes not only dopamine d(4) receptors but also 5-ht(2a) and alpha(1) adrenaline receptors, and nra0160, a selective dopamine d(4) receptor antagonist, on pcp-induced abnormal behavior, and accompanying increases in extracellular levels of glutamate in the medial prefrontal cortex. |
2004-02-23 |
2023-08-12 |
rat |
| Laurent P Lacroix, Lee A Dawson, Jim J Hagan, Christian A Heidbrede. 5-HT6 receptor antagonist SB-271046 enhances extracellular levels of monoamines in the rat medial prefrontal cortex. Synapse (New York, N.Y.). vol 51. issue 2. 2004-02-09. PMID:14618683. |
the present study investigated the neurochemical effects of the selective 5-ht(6) receptor antagonist sb-271046 in the rat medial prefrontal cortex (mpfc). |
2004-02-09 |
2023-08-12 |
rat |
| Mercè Amargós-Bosch, Albert Adell, Analía Bortolozzi, Francesc Artiga. Stimulation of alpha1-adrenoceptors in the rat medial prefrontal cortex increases the local in vivo 5-hydroxytryptamine release: reversal by antipsychotic drugs. Journal of neurochemistry. vol 87. issue 4. 2004-01-14. PMID:14622114. |
stimulation of alpha1-adrenoceptors in the rat medial prefrontal cortex increases the local in vivo 5-hydroxytryptamine release: reversal by antipsychotic drugs. |
2004-01-14 |
2023-08-12 |
rat |
| Analía Bortolozzi, Mercè Amargós-Bosch, Albert Adell, Llorenç Díaz-Mataix, Jordi Serrats, Sebastià Pons, Francesc Artiga. In vivo modulation of 5-hydroxytryptamine release in mouse prefrontal cortex by local 5-HT(2A) receptors: effect of antipsychotic drugs. The European journal of neuroscience. vol 18. issue 5. 2003-10-23. PMID:12956722. |
the application of the 5-hydroxytryptamine2a/2c agonist doi (100 microm) by reverse dialysis in the medial prefrontal cortex doubled the local release of 5-hydroxytryptamine. |
2003-10-23 |
2023-08-12 |
mouse |
| Analía Bortolozzi, Mercè Amargós-Bosch, Albert Adell, Llorenç Díaz-Mataix, Jordi Serrats, Sebastià Pons, Francesc Artiga. In vivo modulation of 5-hydroxytryptamine release in mouse prefrontal cortex by local 5-HT(2A) receptors: effect of antipsychotic drugs. The European journal of neuroscience. vol 18. issue 5. 2003-10-23. PMID:12956722. |
these observations suggest that doi increases 5-hydroxytryptamine release in the mouse medial prefrontal cortex through the activation of local 5-hydroxytryptamine2a receptors by an impulse-dependent mechanism that involves/requires the activation of local alpha-amino-3-hydroxy-5-methyl-4-isoxazole-4-propionate receptors. |
2003-10-23 |
2023-08-12 |
mouse |
| Sondra T Bland, David Hargrave, Julie L Pepin, Jose Amat, Linda R Watkins, Steven F Maie. Stressor controllability modulates stress-induced dopamine and serotonin efflux and morphine-induced serotonin efflux in the medial prefrontal cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 9. 2003-10-06. PMID:12784102. |
stressor controllability modulates stress-induced dopamine and serotonin efflux and morphine-induced serotonin efflux in the medial prefrontal cortex. |
2003-10-06 |
2023-08-12 |
rat |
| Catharine A Winstanley, Yogita Chudasama, Jeffrey W Dalley, David E H Theobald, Jeffrey C Glennon, Trevor W Robbin. Intra-prefrontal 8-OH-DPAT and M100907 improve visuospatial attention and decrease impulsivity on the five-choice serial reaction time task in rats. Psychopharmacology. vol 167. issue 3. 2003-09-24. PMID:12677356. |
however, it is not known precisely how serotonin (5-ht) modulates the medial prefrontal cortex (mpfc) to affect cognitive function and behaviour. |
2003-09-24 |
2023-08-12 |
rat |
| M Victoria Puig, Pau Celada, Llorenç Díaz-Mataix, Francesc Artiga. In vivo modulation of the activity of pyramidal neurons in the rat medial prefrontal cortex by 5-HT2A receptors: relationship to thalamocortical afferents. Cerebral cortex (New York, N.Y. : 1991). vol 13. issue 8. 2003-09-03. PMID:12853374. |
the activation of 5-ht(2a) receptors in medial prefrontal cortex (mpfc) by the hallucinogen doi increases the firing activity of dorsal raphe (dr) 5-ht neurons and prefrontal 5-ht release. |
2003-09-03 |
2023-08-12 |
rat |
| Eleni T Tzavara, Richard J Davis, Kenneth W Perry, Xia Li, Craig Salhoff, Frank P Bymaster, Jeffrey M Witkin, George G Nomiko. The CB1 receptor antagonist SR141716A selectively increases monoaminergic neurotransmission in the medial prefrontal cortex: implications for therapeutic actions. British journal of pharmacology. vol 138. issue 4. 2003-08-27. PMID:12598408. |
sr141716a moderately increased serotonin efflux and concentrations of its metabolite 5-hiaa, both in the medial prefrontal cortex and the nucleus accumbens, and increased norepinephrine, dopamine and their metabolites in the medial prefrontal cortex. |
2003-08-27 |
2023-08-12 |
mouse |
| A M Gardier, D J David, G Jego, C Przybylski, C Jacquot, S Durier, B Gruwez, E Douvier, P Beauverie, N Poisson, R Hen, M Bouri. Effects of chronic paroxetine treatment on dialysate serotonin in 5-HT1B receptor knockout mice. Journal of neurochemistry. vol 86. issue 1. 2003-08-26. PMID:12807420. |
the role of serotonin (5-ht)1b receptors in the mechanism of action of selective serotonin re-uptake inhibitors (ssri) was studied by using intracerebral in vivo microdialysis in conscious, freely moving wild-type and 5-ht1b receptor knockout (ko 5-ht1b) mice in order to compare the effects of chronic administration of paroxetine via osmotic minipumps (1 mg per kg per day for 14 days) on extracellular 5-ht levels ([5-ht]ext) in the medial prefrontal cortex and ventral hippocampus. |
2003-08-26 |
2023-08-12 |
mouse |
| A M Gardier, D J David, G Jego, C Przybylski, C Jacquot, S Durier, B Gruwez, E Douvier, P Beauverie, N Poisson, R Hen, M Bouri. Effects of chronic paroxetine treatment on dialysate serotonin in 5-HT1B receptor knockout mice. Journal of neurochemistry. vol 86. issue 1. 2003-08-26. PMID:12807420. |
basal [5-ht]ext values in the medial prefrontal cortex and ventral hippocampus, approximately 20 h after removing the minipump, were not altered by chronic paroxetine treatment in both genotypes. |
2003-08-26 |
2023-08-12 |
mouse |
| A M Gardier, D J David, G Jego, C Przybylski, C Jacquot, S Durier, B Gruwez, E Douvier, P Beauverie, N Poisson, R Hen, M Bouri. Effects of chronic paroxetine treatment on dialysate serotonin in 5-HT1B receptor knockout mice. Journal of neurochemistry. vol 86. issue 1. 2003-08-26. PMID:12807420. |
conversely, in the medial prefrontal cortex, the paroxetine challenge increased [5-ht]ext similarly in saline-pretreated mice of both genotypes. |
2003-08-26 |
2023-08-12 |
mouse |
| A M Gardier, D J David, G Jego, C Przybylski, C Jacquot, S Durier, B Gruwez, E Douvier, P Beauverie, N Poisson, R Hen, M Bouri. Effects of chronic paroxetine treatment on dialysate serotonin in 5-HT1B receptor knockout mice. Journal of neurochemistry. vol 86. issue 1. 2003-08-26. PMID:12807420. |
by using the zero net flux method of quantitative microdialysis in the medial prefrontal cortex and ventral hippocampus of wild-type and ko 5-ht1b mice, we found that basal [5-ht]ext and the extraction fraction of 5-ht were similar in the medial prefrontal cortex and ventral hippocampus of both genotypes, suggesting that no compensatory response to the constitutive deletion of the 5-ht1b receptor involving changes in 5-ht uptake capacity occurred in vivo. |
2003-08-26 |
2023-08-12 |
mouse |
| A M Gardier, D J David, G Jego, C Przybylski, C Jacquot, S Durier, B Gruwez, E Douvier, P Beauverie, N Poisson, R Hen, M Bouri. Effects of chronic paroxetine treatment on dialysate serotonin in 5-HT1B receptor knockout mice. Journal of neurochemistry. vol 86. issue 1. 2003-08-26. PMID:12807420. |
these data suggest that there are differences between the ventral hippocampus and medial prefrontal cortex in activation of terminal 5-ht1b autoreceptors and their role in regulating dialysate 5-ht levels. |
2003-08-26 |
2023-08-12 |
mouse |
| Toshihide Kuroki, Herbert Y Meltzer, Junji Ichikaw. 5-HT 2A receptor stimulation by DOI, a 5-HT 2A/2C receptor agonist, potentiates amphetamine-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens. Brain research. vol 972. issue 1-2. 2003-07-11. PMID:12711095. |
5-ht 2a receptor stimulation by doi, a 5-ht 2a/2c receptor agonist, potentiates amphetamine-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens. |
2003-07-11 |
2023-08-12 |
rat |
| Toshihide Kuroki, Herbert Y Meltzer, Junji Ichikaw. 5-HT 2A receptor stimulation by DOI, a 5-HT 2A/2C receptor agonist, potentiates amphetamine-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens. Brain research. vol 972. issue 1-2. 2003-07-11. PMID:12711095. |
(+/-)-([1-(2,5-dimethoxy-4-iodophenyl)-aminopropane]-hydrochloride) (doi) (2.5 mg/kg), a 5-ht(2a/2c) agonist, significantly potentiated d-amphetamine (amph) (1 mg/kg)-induced dopamine (da) release in rat medial prefrontal cortex (mpfc) and nucleus accumbens (nac). |
2003-07-11 |
2023-08-12 |
rat |