| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lu Zhang, Qian-Dong Wang, Hua-Meng Shi, Jian-Chun Pa. [Influence of ferulic acid on the pain-depression dyad induced by reserpine]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 48. issue 1. 2014-01-16. PMID:23600138. |
the results suggested that reserpine significantly increased the level of nitrite in hippocampus and frontal cortex and reduced the levels of sod, 5-ht and ne in these two brain regions. |
2014-01-16 |
2023-08-12 |
mouse |
| Reiko T Roppongi, Nobuhiko Kojima, Kenji Hanamura, Hiroyuki Yamazaki, Tomoaki Shira. Selective reduction of drebrin and actin in dendritic spines of hippocampal neurons by activation of 5-HT(2A) receptors. Neuroscience letters. vol 547. 2014-01-16. PMID:23684573. |
selective reduction of drebrin and actin in dendritic spines of hippocampal neurons by activation of 5-ht(2a) receptors. |
2014-01-16 |
2023-08-12 |
Not clear |
| Reiko T Roppongi, Nobuhiko Kojima, Kenji Hanamura, Hiroyuki Yamazaki, Tomoaki Shira. Selective reduction of drebrin and actin in dendritic spines of hippocampal neurons by activation of 5-HT(2A) receptors. Neuroscience letters. vol 547. 2014-01-16. PMID:23684573. |
in the present study, we examined the effect of 5-ht(2a) receptor activation on the actin cytoskeleton in dendritic spines of mature hippocampal neurons in low-density culture. |
2014-01-16 |
2023-08-12 |
Not clear |
| Simona Spinelli, Tanja Müller, Miriam Friedel, Hannes Sigrist, Klaus-Peter Lesch, Mark Henkelman, Markus Rudin, Erich Seifritz, Christopher R Pryc. Effects of repeated adolescent stress and serotonin transporter gene partial knockout in mice on behaviors and brain structures relevant to major depression. Frontiers in behavioral neuroscience. vol 7. 2014-01-15. PMID:24427124. |
in humans, exposure to stress during development is associated with structural and functional alterations of the prefrontal cortex (pfc), amygdala (amy), and hippocampus (hc) and their circuits of connectivity, and with an increased risk for developing major depressive disorder particularly in carriers of the short (s) variant of the serotonin transporter (5-htt) gene-linked polymorphic region (5-httlpr). |
2014-01-15 |
2023-08-12 |
mouse |
| Stéphanie Pain, Alice Gochard, Sylvie Bodard, Zuhal Gulhan, Caroline Prunier-Aesch, Sylvie Chalo. Toxicity of MPTP on neurotransmission in three mouse models of Parkinson's disease. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 65. issue 5. 2014-01-07. PMID:23083629. |
moreover, a decrease of serotonin level was observed in midbrain and hippocampus of acute and sub-acute intoxicated-mice. |
2014-01-07 |
2023-08-12 |
mouse |
| G Clarke, S Grenham, P Scully, P Fitzgerald, R D Moloney, F Shanahan, T G Dinan, J F Crya. The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner. Molecular psychiatry. vol 18. issue 6. 2014-01-03. PMID:22688187. |
here we show that male gf animals have a significant elevation in the hippocampal concentration of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid, its main metabolite, compared with conventionally colonised control animals. |
2014-01-03 |
2023-08-12 |
Not clear |
| Fuencisla Pilar-Cuéllar, Rebeca Vidal, Alvaro Díaz, Elena Castro, Severiano dos Anjos, Jesús Pascual-Brazo, Raquel Linge, Veronica Vargas, Helena Blanco, Beatriz Martínez-Villayandre, Ángel Pazos, Elsa M Valdizá. Neural plasticity and proliferation in the generation of antidepressant effects: hippocampal implication. Neural plasticity. vol 2013. 2013-12-30. PMID:23862076. |
we will especially focus on the hippocampal cellularity and plasticity modulation by serotonin, trophic factors as brain-derived neurotrophic factor (bdnf), and vascular endothelial growth factor (vegf) through intracellular signalling pathways-camp, wnt/ β -catenin, and mtor. |
2013-12-30 |
2023-08-12 |
Not clear |
| Margherita Zotti, Marilena Colaianna, Maria Grazia Morgese, Paolo Tucci, Stefania Schiavone, Pinarosa Avato, Luigia Trabac. Carvacrol: from ancient flavoring to neuromodulatory agent. Molecules (Basel, Switzerland). vol 18. issue 6. 2013-12-24. PMID:23708230. |
), was able to increase dopamine and serotonin levels in the prefrontal cortex and hippocampus. |
2013-12-24 |
2023-08-12 |
rat |
| Margherita Zotti, Marilena Colaianna, Maria Grazia Morgese, Paolo Tucci, Stefania Schiavone, Pinarosa Avato, Luigia Trabac. Carvacrol: from ancient flavoring to neuromodulatory agent. Molecules (Basel, Switzerland). vol 18. issue 6. 2013-12-24. PMID:23708230. |
acute carvacrol administration only significantly reduced serotonin content in either the prefrontal cortex or in the hippocampus at the highest dose. |
2013-12-24 |
2023-08-12 |
rat |
| G Quesseveur, D J David, M C Gaillard, P Pla, M V Wu, H T Nguyen, V Nicolas, G Auregan, I David, A Dranovsky, P Hantraye, R Hen, A M Gardier, N Déglon, B P Guiar. BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities. Translational psychiatry. vol 3. 2013-12-23. PMID:23632457. |
at nerve terminal such as the hippocampus, the enhancement of 5-ht availability increases brain-derived neurotrophic factor (bdnf) synthesis and signaling, a major event in the stimulation of adult neurogenesis. |
2013-12-23 |
2023-08-12 |
mouse |
| Man Tang, Jieyu Lei, Xiao Sun, Guojun Liu, Shulei Zha. Stress-induced anhedonia correlates with lower hippocampal serotonin transporter protein expression. Brain research. vol 1513. 2013-12-16. PMID:23558306. |
stress-induced anhedonia correlates with lower hippocampal serotonin transporter protein expression. |
2013-12-16 |
2023-08-12 |
mouse |
| Li-Tao Yi, Jing Li, Qing Liu, Di Geng, Ya-Fei Zhou, Xiao-Qing Ke, Huan Chen, Lian-Jin Wen. Antidepressant-like effect of oleanolic acid in mice exposed to the repeated forced swimming test. Journal of psychopharmacology (Oxford, England). vol 27. issue 5. 2013-11-26. PMID:23151611. |
furthermore, chronic administration of oleanolic acid significantly increased serotonin (5-ht) levels (frontal cortex: 44.5%, 41.9%, 27.5% for 10, 20, 40 mg/kg; hippocampus: 57.2%, 80.9% for 10, 20 mg/kg), decreased 5-hydroxyindoleacetic acid (5-hiaa)/5-ht ratio (frontal cortex: 31.6%, 30.1%, 23.5%; hippocampus: 40.6%, 47.7%, 29.2% for 10, 20, 40 mg/kg) and elevated norepinephrine (ne) levels (hippocampus: 20 mg/kg, 45.4%) but did not alter dopamine (da) levels. |
2013-11-26 |
2023-08-12 |
mouse |
| Alvaro L García-García, Elisabet Venzala, Natalia Elizalde, M J Ramírez, Ahinoa Urbiola, Joaquin Del Rio, Laurence Lanfumey, Rosa M Torder. Regulation of serotonin (5-HT) function by a VGLUT1 dependent glutamate pathway. Neuropharmacology. vol 70. 2013-11-26. PMID:23168115. |
these mice showed decreased induced neuronal activity in 5-ht cells bodies and in different forebrain areas, as well as decreased hippocampal cell proliferation and 5-ht turnover. |
2013-11-26 |
2023-08-12 |
mouse |
| G L Kovács, J Kishonti, K Lissák, G Telegd. Dose-dependent dual effect of corticosterone on cerebral 5-HT metabolism. Neurochemical research. vol 2. issue 3. 2013-11-26. PMID:24272058. |
a 1.0 mg/kg dose of corticosterone increased the serotonin content and turnover in the hypothalamus and mesencephalon 30 min after administration; however, it was ineffective on dorsal hippocampus and frontal and parietal cortex. |
2013-11-26 |
2023-08-12 |
Not clear |
| Nathan C Mitchell, Georgianna G Gould, Corey M Smolik, Wouter Koek, Lynette C Daw. Antidepressant-like drug effects in juvenile and adolescent mice in the tail suspension test: Relationship with hippocampal serotonin and norepinephrine transporter expression and function. Frontiers in pharmacology. vol 4. 2013-11-05. PMID:24191152. |
antidepressant-like drug effects in juvenile and adolescent mice in the tail suspension test: relationship with hippocampal serotonin and norepinephrine transporter expression and function. |
2013-11-05 |
2023-08-12 |
mouse |
| Nathan C Mitchell, Georgianna G Gould, Corey M Smolik, Wouter Koek, Lynette C Daw. Antidepressant-like drug effects in juvenile and adolescent mice in the tail suspension test: Relationship with hippocampal serotonin and norepinephrine transporter expression and function. Frontiers in pharmacology. vol 4. 2013-11-05. PMID:24191152. |
the smaller antidepressant response of juveniles was not related to either maximal binding (b max) or affinity (k d) for [(3)h]citalopram binding to the serotonin transporter (sert) in hippocampus, which did not vary significantly among ages. |
2013-11-05 |
2023-08-12 |
mouse |
| Darrick T Balu, Jill R Turner, Bethany R Brookshire, Tiffany E Hill-Smith, Julie A Blendy, Irwin Luck. Brain monoamines and antidepressant-like responses in MRL/MpJ versus C57BL/6J mice. Neuropharmacology. vol 67. 2013-11-04. PMID:23220293. |
however, acute administration of the selective serotonin reuptake inhibitor citalopram produced an increase in extracellular serotonin in the ventral hippocampus of mrl/mpj mice that was twice as large as achieved in c57bl/6j mice. |
2013-11-04 |
2023-08-12 |
mouse |
| Darrick T Balu, Jill R Turner, Bethany R Brookshire, Tiffany E Hill-Smith, Julie A Blendy, Irwin Luck. Brain monoamines and antidepressant-like responses in MRL/MpJ versus C57BL/6J mice. Neuropharmacology. vol 67. 2013-11-04. PMID:23220293. |
the greater effects in mrl/mpj mice on 5-ht levels were not maintained after local perfusion of citalopram, suggesting that mechanisms outside of the hippocampus were responsible for the greater effect of citalopram after systemic injection. |
2013-11-04 |
2023-08-12 |
mouse |
| Darrick T Balu, Jill R Turner, Bethany R Brookshire, Tiffany E Hill-Smith, Julie A Blendy, Irwin Luck. Brain monoamines and antidepressant-like responses in MRL/MpJ versus C57BL/6J mice. Neuropharmacology. vol 67. 2013-11-04. PMID:23220293. |
the density of serotonin and norepinephrine transporters in the hippocampus was significantly higher in mrl/mpj mice. |
2013-11-04 |
2023-08-12 |
mouse |
| Darrick T Balu, Jill R Turner, Bethany R Brookshire, Tiffany E Hill-Smith, Julie A Blendy, Irwin Luck. Brain monoamines and antidepressant-like responses in MRL/MpJ versus C57BL/6J mice. Neuropharmacology. vol 67. 2013-11-04. PMID:23220293. |
in addition, the expression of 5-ht(1a) mrna was lower in the hippocampus, 5-ht(1b) mrna was higher in the hippocampus and brainstem and sert mrna was higher in the brain stem of mrl/mpj mice. |
2013-11-04 |
2023-08-12 |
mouse |