| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H A Gromova, A R Chubakov, E I Chumasov, H V Konovalo. Serotonin as a stimulator of hippocampal cell differentiation in tissue culture. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 1. issue 6. 2014-06-02. PMID:24873688. |
these results indicate that 5-ht stimulates the differentiation of hippocampal cells in tissue culture. |
2014-06-02 |
2023-08-13 |
rat |
| Yingcong Yu, Rui Wang, Chunbai Chen, Xia Du, Lina Ruan, Jiao Sun, Jianxin Li, Lu Zhang, James M O'Donnell, Jianchun Pan, Ying X. Antidepressant-like effect of trans-resveratrol in chronic stress model: behavioral and neurochemical evidences. Journal of psychiatric research. vol 47. issue 3. 2014-05-30. PMID:23174668. |
the neurochemical assay showed that higher dose of trans-resveratrol (80 mg/kg) produced a marked increase of 5-ht levels in three brain regions, the frontal cortex, hippocampus and hypothalamus. |
2014-05-30 |
2023-08-12 |
rat |
| Christian Webhofer, Philipp Gormanns, Stefan Reckow, Maria Lebar, Giuseppina Maccarrone, Tonia Ludwig, Benno Pütz, John M Asara, Florian Holsboer, Inge Sillaber, Walter Zieglgänsberger, Christoph W Turc. Proteomic and metabolomic profiling reveals time-dependent changes in hippocampal metabolism upon paroxetine treatment and biomarker candidates. Journal of psychiatric research. vol 47. issue 3. 2014-05-30. PMID:23207114. |
in the present study we aimed at identifying hippocampal cellular pathway alterations in dba/2 mice using paroxetine as a representative selective serotonin reuptake inhibitor (ssri). |
2014-05-30 |
2023-08-12 |
mouse |
| S Migliarini, G Pacini, B Pelosi, G Lunardi, M Pasqualett. Lack of brain serotonin affects postnatal development and serotonergic neuronal circuitry formation. Molecular psychiatry. vol 18. issue 10. 2014-05-29. PMID:23007167. |
finally, we demonstrated that bdnf expression is significantly up-regulated in the hippocampus of mice lacking brain 5-ht, mirroring the timing of the appearance of hyperinnervation and thus unmasking a possible regulatory feedback mechanism tuning the serotonergic neuronal circuitry formation. |
2014-05-29 |
2023-08-12 |
mouse |
| T M Eriksson, A Alvarsson, T L Stan, X Zhang, K N Hascup, E R Hascup, J Kehr, G A Gerhardt, J Warner-Schmidt, M Arango-Lievano, M G Kaplitt, S O Ogren, P Greengard, P Svenningsso. Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11. Molecular psychiatry. vol 18. issue 10. 2014-05-29. PMID:23032875. |
unexpectedly, 5-ht(1b)r agonist stimulation enhanced memory in p11ko mice, and this atypical switch was reversed after hippocampal adeno-associated virus mediated gene transfer of p11. |
2014-05-29 |
2023-08-12 |
mouse |
| T M Eriksson, A Alvarsson, T L Stan, X Zhang, K N Hascup, E R Hascup, J Kehr, G A Gerhardt, J Warner-Schmidt, M Arango-Lievano, M G Kaplitt, S O Ogren, P Greengard, P Svenningsso. Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11. Molecular psychiatry. vol 18. issue 10. 2014-05-29. PMID:23032875. |
notably, 5-ht(1b)r stimulation increased glutamatergic neurotransmission in the hippocampus in p11ko mice, but not in wt mice, as measured by both pre- and postsynaptic criteria. |
2014-05-29 |
2023-08-12 |
mouse |
| T M Eriksson, A Alvarsson, T L Stan, X Zhang, K N Hascup, E R Hascup, J Kehr, G A Gerhardt, J Warner-Schmidt, M Arango-Lievano, M G Kaplitt, S O Ogren, P Greengard, P Svenningsso. Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11. Molecular psychiatry. vol 18. issue 10. 2014-05-29. PMID:23032875. |
magnetic resonance spectroscopy demonstrated global hippocampal reductions of inhibitory gaba, which may contribute to the memory enhancement and potentiation of pre- and post-synaptic measures of glutamate transmission by a 5-ht(1b)r agonist in p11ko mice. |
2014-05-29 |
2023-08-12 |
mouse |
| T M Eriksson, A Alvarsson, T L Stan, X Zhang, K N Hascup, E R Hascup, J Kehr, G A Gerhardt, J Warner-Schmidt, M Arango-Lievano, M G Kaplitt, S O Ogren, P Greengard, P Svenningsso. Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11. Molecular psychiatry. vol 18. issue 10. 2014-05-29. PMID:23032875. |
it is concluded that the level of hippocampal p11 determines the directionality of 5-ht(1b)r action on emotional memory processing and modulates hippocampal functionality. |
2014-05-29 |
2023-08-12 |
mouse |
| Mette Ewers Haahr, Patrick Fisher, Klaus Holst, Karine Madsen, Christian Gaden Jensen, Lisbeth Marner, Szabols Lehel, William Baaré, Gitte Knudsen, Steen Hasselbalc. The 5-HT4 receptor levels in hippocampus correlates inversely with memory test performance in humans. Human brain mapping. vol 34. issue 11. 2014-05-28. PMID:22736538. |
the cerebral serotonin (5-ht) system is involved in cognitive functions such as memory and learning and animal studies have repeatedly shown that stimulation of the 5-ht type 4 receptor (5-ht4 r) facilitates memory and learning and further that the 5-ht4 r modulates cellular memory processes in hippocampus. |
2014-05-28 |
2023-08-12 |
human |
| Gergely Orban, Massimo Pierucci, Arcangelo Benigno, Mauro Pessia, Salvatore Galati, Mario Valentino, Richard Muscat, Giuseppe Di Giovann. High dose of 8-OH-DPAT decreases maximal dentate gyrus activation and facilitates granular cell plasticity in vivo. Experimental brain research. vol 230. issue 4. 2014-05-27. PMID:23780309. |
although several studies have emphasized a crucial role for the serotonergic system in the control of hippocampal excitability, the role of serotonin (5-ht) and its receptors in normal and pathologic conditions, such as temporal lobe epilepsy (tle), is still unclear. |
2014-05-27 |
2023-08-12 |
rat |
| María Esther Olvera-Cortés, Blanca Erika Gutiérrez-Guzmán, Elisa López-Loeza, J Jesús Hernández-Pérez, Miguel Angel López-Vázque. Serotonergic modulation of hippocampal theta activity in relation to hippocampal information processing. Experimental brain research. vol 230. issue 4. 2014-05-27. PMID:23990128. |
serotonin is recognized as the only neurotransmitter able to desynchronize the hippocampal electroencephalographic. |
2014-05-27 |
2023-08-12 |
Not clear |
| María Esther Olvera-Cortés, Blanca Erika Gutiérrez-Guzmán, Elisa López-Loeza, J Jesús Hernández-Pérez, Miguel Angel López-Vázque. Serotonergic modulation of hippocampal theta activity in relation to hippocampal information processing. Experimental brain research. vol 230. issue 4. 2014-05-27. PMID:23990128. |
a theory has been developed in which serotonin, acting on medial septal neurons, modulates cholinergic/gabaergic inputs to the hippocampus and, thus, the cognitive processing mediated by this area. |
2014-05-27 |
2023-08-12 |
Not clear |
| María Esther Olvera-Cortés, Blanca Erika Gutiérrez-Guzmán, Elisa López-Loeza, J Jesús Hernández-Pérez, Miguel Angel López-Vázque. Serotonergic modulation of hippocampal theta activity in relation to hippocampal information processing. Experimental brain research. vol 230. issue 4. 2014-05-27. PMID:23990128. |
in this review, we present a summary and analysis of the data relating serotonin and its theta activity modulation with cognition, and we also discuss the few works relating serotonin, theta activity and cognition as well as the theories regarding the serotonin regulation of memory processes organized by the hippocampus. |
2014-05-27 |
2023-08-12 |
Not clear |
| María Esther Olvera-Cortés, Blanca Erika Gutiérrez-Guzmán, Elisa López-Loeza, J Jesús Hernández-Pérez, Miguel Angel López-Vázque. Serotonergic modulation of hippocampal theta activity in relation to hippocampal information processing. Experimental brain research. vol 230. issue 4. 2014-05-27. PMID:23990128. |
we propose that serotonin depletion induces impairment of the relays coding the frequency of hippocampal theta activity, whereas depletion of the relays in which frequency is not coded induces improvements in spatial learning that are related to increased expression of high-frequency theta activity. |
2014-05-27 |
2023-08-12 |
Not clear |
| Marjolein S Kops, Elske N de Haas, T Bas Rodenburg, Esther D Ellen, Gerdien A H Korte-Bouws, Berend Olivier, O Güntürkün, J Elizabeth Bolhuis, S Mechiel Kort. Effects of feather pecking phenotype (severe feather peckers, victims and non-peckers) on serotonergic and dopaminergic activity in four brain areas of laying hens (Gallus gallus domesticus). Physiology & behavior. vol 120. 2014-05-26. PMID:23911692. |
5-ht turnover levels did not differ between phenotypes in medial striatum, arcopallium and hippocampus. |
2014-05-26 |
2023-08-12 |
Not clear |
| Sinead E Shortall, Alice E Macerola, Rabbi T R Swaby, Rebecca Jayson, Chantal Korsah, Katharine E Pillidge, Peter M Wigmore, Francis J P Ebling, A Richard Green, Kevin C F Fone, Madeleine V Kin. Behavioural and neurochemical comparison of chronic intermittent cathinone, mephedrone and MDMA administration to the rat. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 9. 2014-05-01. PMID:23051939. |
dopamine, 5-hydroxytryptamine (5-ht) and their major metabolites were measured in striatum, frontal cortex and hippocampus by high performance liquid chromatography 7 days after intermittent dosing and 2h after acute injection. |
2014-05-01 |
2023-08-12 |
rat |
| Sinead E Shortall, Alice E Macerola, Rabbi T R Swaby, Rebecca Jayson, Chantal Korsah, Katharine E Pillidge, Peter M Wigmore, Francis J P Ebling, A Richard Green, Kevin C F Fone, Madeleine V Kin. Behavioural and neurochemical comparison of chronic intermittent cathinone, mephedrone and MDMA administration to the rat. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 9. 2014-05-01. PMID:23051939. |
acute mdma reduced hippocampal 5-ht and 5-hiaa but the only significant effect on dopamine, 5-ht and their metabolites following chronic dosing was altered hippocampal 3,4-dihydroxyphenylacetic acid (dopac), following mephedrone (4, 10mg/kg) and mdma. |
2014-05-01 |
2023-08-12 |
rat |
| Alan L Pehrson, Thomas Cremers, Cecile Bétry, Marieke G C van der Hart, Laerke Jørgensen, Mathias Madsen, Nasser Haddjeri, Bjarke Ebert, Connie Sanche. Lu AA21004, a novel multimodal antidepressant, produces regionally selective increases of multiple neurotransmitters--a rat microdialysis and electrophysiology study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 2. 2014-04-21. PMID:22612991. |
extracellular 5-ht, ne and da levels were evaluated in the ventral hippocampus (vhc), medial prefrontal cortex (mpfc) and nucleus accumbens (nac) after acute and subchronic treatment with lu aa21004 or escitalopram. |
2014-04-21 |
2023-08-12 |
rat |
| Sang Bae Yoo, Bom-Taeck Kim, Jin Young Kim, Vitaly Ryu, Dong-Won Kang, Jong-Ho Lee, Jeong Won Jahn. Adolescence fluoxetine increases serotonergic activity in the raphe-hippocampus axis and improves depression-like behaviors in female rats that experienced neonatal maternal separation. Psychoneuroendocrinology. vol 38. issue 6. 2014-04-21. PMID:23010142. |
fluoxetine normalized ms-induced decrease of the raphe 5-ht levels and increased 5-ht metabolism in the hippocampus in ms females, and increased the hypothalamic 5-ht both in nh and ms. fluoxetine decreased the raphe 5-ht and increased the plasma corticosterone in nh females. |
2014-04-21 |
2023-08-12 |
rat |
| Ting-Ching Wu, Han-Ting Chen, Han-Ying Chang, Ching-Yao Yang, Mei-Chun Hsiao, Mei-Ling Cheng, Jin-Chung Che. Mineralocorticoid receptor antagonist spironolactone prevents chronic corticosterone induced depression-like behavior. Psychoneuroendocrinology. vol 38. issue 6. 2014-04-21. PMID:23044404. |
the results show that chronic corticosterone-treated animals displayed an increased immobility time in a forced-swimming test, decreased preference to sucrose solution and novel object recognition performance, and enhanced hippocampal serotonin but decreased mr expression in both hippocampus and hypothalamus. |
2014-04-21 |
2023-08-12 |
mouse |