| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Li-Ping Guan, Li-Ming Tang, Cheng-Yan Pan, Shui-Lian Zhao, Si-Hong Wan. Evaluation of potential antidepressant-like activity of chalcone-1203 in various murine experimental depressant models. Neurochemical research. vol 39. issue 2. 2014-10-07. PMID:24343532. |
chalcone-1203 also significantly reduced the ratio of 5-hiaa/5-ht in the hippocampus and cortex, shown down 5-ht metabolism compared with mice treated with stress vehicle. |
2014-10-07 |
2023-08-12 |
mouse |
| Li-Ping Guan, Li-Ming Tang, Cheng-Yan Pan, Shui-Lian Zhao, Si-Hong Wan. Evaluation of potential antidepressant-like activity of chalcone-1203 in various murine experimental depressant models. Neurochemical research. vol 39. issue 2. 2014-10-07. PMID:24343532. |
in conclusion, chalcone-1203 produced significant antidepressant-like activity, and the mechanism of action may be due to increased 5-ht and ne in the mouse hippocampus and cortex. |
2014-10-07 |
2023-08-12 |
mouse |
| Sumitaka Inoue, Hiroki Shikanai, Machiko Matsumoto, Sachiko Hiraide, Yasuhiro Saito, Yoshiki Yanagawa, Mitsuhiro Yoshioka, Kei-ichi Shimamura, Hiroko Togash. Metaplastic regulation of the median raphe nucleus via serotonin 5-HT1A receptor on hippocampal synaptic plasticity is associated with gender-specific emotional expression in rats. Journal of pharmacological sciences. vol 124. issue 3. 2014-09-30. PMID:24599137. |
metaplastic regulation of the median raphe nucleus via serotonin 5-ht1a receptor on hippocampal synaptic plasticity is associated with gender-specific emotional expression in rats. |
2014-09-30 |
2023-08-12 |
rat |
| Sumitaka Inoue, Hiroki Shikanai, Machiko Matsumoto, Sachiko Hiraide, Yasuhiro Saito, Yoshiki Yanagawa, Mitsuhiro Yoshioka, Kei-ichi Shimamura, Hiroko Togash. Metaplastic regulation of the median raphe nucleus via serotonin 5-HT1A receptor on hippocampal synaptic plasticity is associated with gender-specific emotional expression in rats. Journal of pharmacological sciences. vol 124. issue 3. 2014-09-30. PMID:24599137. |
extracellular 5-ht levels in the hippocampus were increased by cfc only in the males. |
2014-09-30 |
2023-08-12 |
rat |
| Raphaelle Mottolese, Jérôme Redouté, Nicolas Costes, Didier Le Bars, Angela Sirig. Switching brain serotonin with oxytocin. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 23. 2014-09-30. PMID:24912179. |
importantly, the amygdala appears central in the regulation of 5-ht by oxt: [(18)f]mppf bpnd changes in the drn correlated with changes in right amygdala, which were in turn correlated with changes in hippocampus, insula, subgenual, and orbitofrontal cortex, a circuit implicated in the control of stress, mood, and social behaviors. |
2014-09-30 |
2023-08-13 |
human |
| Zlatina Petkova, Jana Tchekalarova, Daniela Pechlivanova, Slavianka Moyanova, Lidia Kortenska, Rumiana Mitreva, Deyan Popov, Petya Markova, Valentin Lozanov, Dimitrina Atanasova, Nikolai Lazarov, Alexander Stoyne. Treatment with melatonin after status epilepticus attenuates seizure activity and neuronal damage but does not prevent the disturbance in diurnal rhythms and behavioral alterations in spontaneously hypertensive rats in kainate model of temporal lobe epilepsy. Epilepsy & behavior : E&B. vol 31. 2014-09-29. PMID:24440891. |
melatonin reduced neuronal damage specifically in the ca1 area of the hippocampus and piriform cortex and decreased hippocampal serotonin (5-ht) levels both in control and epileptic shrs. |
2014-09-29 |
2023-08-12 |
rat |
| Xuan Liu, Junjian Zhang, Dong Sun, Yuanteng Fan, Hongbin Zhou, Binfang F. Effects of fluoxetine on brain-derived neurotrophic factor serum concentration and cognition in patients with vascular dementia. Clinical interventions in aging. vol 9. 2014-09-29. PMID:24648723. |
selective serotonin reuptake inhibitors improve cognition in patients with stroke and increase the expression of brain-derived neurotrophic factor (bdnf) in the rat hippocampus. |
2014-09-29 |
2023-08-12 |
rat |
| Aline Isabel da Silva, Ligia Cristina Monteiro Galindo, Luciana Nascimento, Cristiane Moura Freitas, Raul Manhaes-de-Castro, Claudia Jacques Lagranha, Sandra Lopes de Souz. Fluoxetine treatment of rat neonates significantly reduces oxidative stress in the hippocampus and in behavioral indicators of anxiety later in postnatal life. Canadian journal of physiology and pharmacology. vol 92. issue 4. 2014-09-26. PMID:24708216. |
the aim of this study was to evaluate the effect of fluoxetine-inhibited serotonin reuptake in nursing rat neonates on behavior and on oxidative stress in the hypothalamus and the hippocampus; brain areas responsible for behavior related to food and anxiety, respectively. |
2014-09-26 |
2023-08-13 |
rat |
| Hyun Jung Kim, Seungwoo Kang, Hyun Ju Kim, Sun-Hye Choi, Seungkeun Shin, Hyung Ha Lee, Hyewhon Rhim, Kyung Ho Shi. Effect of acute and chronic electroconvulsive shock on 5-hydroxytrypamine 6 receptor immunoreactivity in rat hippocampus. Experimental neurobiology. vol 23. issue 3. 2014-09-26. PMID:25258570. |
one potential mechanism underlying both the antidepressant and amnesia effect of ecs may involve the regulation of serotonin (5-hydroxytryptamine) 6 (5-ht6) receptor, but less is known about the effects of acute ecs on the changes in 5-ht6 receptor expression in the hippocampus. |
2014-09-26 |
2023-08-13 |
rat |
| Georg S Kranz, Andreas Hahn, Pia Baldinger, Daniela Haeusler, Cecile Philippe, Ulrike Kaufmann, Wolfgang Wadsak, Markus Savli, Anna Hoeflich, Christoph Kraus, Thomas Vanicek, Markus Mitterhauser, Siegfried Kasper, Rupert Lanzenberge. Cerebral serotonin transporter asymmetry in females, males and male-to-female transsexuals measured by PET in vivo. Brain structure & function. vol 219. issue 1. 2014-09-19. PMID:23224294. |
voxel-wise analysis of serotonin transporter binding in all groups showed both strong left and rightward asymmetries in several cortical and subcortical structures including temporal and frontal cortices, anterior cingulate, hippocampus, caudate and thalamus. |
2014-09-19 |
2023-08-12 |
Not clear |
| Sadia Saleem, Saiqa Tabassum, Sana Ahmed, Tahira Perveen, Saida Haide. Senescence related alteration in hippocampal biogenic amines produces neuropsychological deficits in rats. Pakistan journal of pharmaceutical sciences. vol 27. issue 4. 2014-09-18. PMID:25015449. |
the major goal of the present study was to investigate the age associated cognitive dysfunction and other behavioral changes and their association with age related alterations in levels of neurotransmitters, such as dopamine (da) and serotonin (5-ht) in the hippocampal region. |
2014-09-18 |
2023-08-13 |
rat |
| Sadia Saleem, Saiqa Tabassum, Sana Ahmed, Tahira Perveen, Saida Haide. Senescence related alteration in hippocampal biogenic amines produces neuropsychological deficits in rats. Pakistan journal of pharmaceutical sciences. vol 27. issue 4. 2014-09-18. PMID:25015449. |
a marked decrease in da and 5-ht was observed in the hippocampus of aged rats. |
2014-09-18 |
2023-08-13 |
rat |
| Jesper Bornø Jensen, Kristian Gaarn du Jardin, Dekun Song, David Budac, Gennady Smagin, Connie Sanchez, Alan Lars Pehrso. Vortioxetine, but not escitalopram or duloxetine, reverses memory impairment induced by central 5-HT depletion in rats: evidence for direct 5-HT receptor modulation. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 24. issue 1. 2014-09-12. PMID:24284262. |
four injections of the irreversible tryptophan hydroxylase inhibitor 4-chloro-dl-phenylalanine methyl ester hydrochloride (pcpa, 86mg/kg, s.c.) induced 5-ht depletion, as measured in hippocampal homogenate and microdialysate. |
2014-09-12 |
2023-08-12 |
rat |
| I V Karpova, V V Mikheev, V V Marysheva, E R Bychkov, P D Shabano. [Effect of acute hypoxia with hypercapnia on the content of monoamines in symmetrical brain structures of the BALB/c male mice]. Biomeditsinskaia khimiia. vol 60. issue 2. 2014-09-09. PMID:24837314. |
the concentrations of dopamine, serotonin and their metabolites dihydroxyphenylacetic, homovanilic and 5-hydroxyindolacetic acids were measured by hplc in the brain cortex, hippocampus and striatum of the right and the left hemispheres. |
2014-09-09 |
2023-08-13 |
mouse |
| I V Karpova, V V Mikheev, V V Marysheva, E R Bychkov, P D Shabano. [Effect of acute hypoxia with hypercapnia on the content of monoamines in symmetrical brain structures of the BALB/c male mice]. Biomeditsinskaia khimiia. vol 60. issue 2. 2014-09-09. PMID:24837314. |
acute hypoxia with hypercapnia decreased the dopamine level in the striatum and the serotonin level both in the hippocampus and the brain cortex. |
2014-09-09 |
2023-08-13 |
mouse |
| Meghan R Hennis, Marian A Marvin, Charles M Taylor, Matthew S Goldber. Surprising behavioral and neurochemical enhancements in mice with combined mutations linked to Parkinson's disease. Neurobiology of disease. vol 62. 2014-09-03. PMID:24075852. |
additionally, parkin(-/-)dj-1(-/-) mice exhibit improved rotarod performance and have increased serotonin in the striatum and hippocampus. |
2014-09-03 |
2023-08-12 |
mouse |
| Claudia Pudell, Bianca A Vicente, Ana M Delattre, Bruno Carabelli, Marco A Mori, Deborah Suchecki, Ricardo B Machado, Sílvio M Zanata, Jesuí V Visentainer, Oscar de Oliveira Santos Junior, Marcelo M S Lima, Anete C Ferra. Fish oil improves anxiety-like, depressive-like and cognitive behaviors in olfactory bulbectomised rats. The European journal of neuroscience. vol 39. issue 2. 2014-09-03. PMID:24191918. |
female rats received supplementation with fo during habituation, mating, gestation, and lactation, and their pups were subjected to obx in adulthood; after the recovery period, the adult offspring were subjected to behavioral tests, and the hippocampal levels of brain-derived neurotrophic factor (bdnf), serotonin (5-ht) and the metabolite 5-hydroxyindoleacetic (5-hiaa) were determined. |
2014-09-03 |
2023-08-12 |
rat |
| Claudia Pudell, Bianca A Vicente, Ana M Delattre, Bruno Carabelli, Marco A Mori, Deborah Suchecki, Ricardo B Machado, Sílvio M Zanata, Jesuí V Visentainer, Oscar de Oliveira Santos Junior, Marcelo M S Lima, Anete C Ferra. Fish oil improves anxiety-like, depressive-like and cognitive behaviors in olfactory bulbectomised rats. The European journal of neuroscience. vol 39. issue 2. 2014-09-03. PMID:24191918. |
obx caused reductions in the levels of hippocampal bdnf and 5-ht, whereas fo supplementation restored these levels to normal values. |
2014-09-03 |
2023-08-12 |
rat |
| Claudia Pudell, Bianca A Vicente, Ana M Delattre, Bruno Carabelli, Marco A Mori, Deborah Suchecki, Ricardo B Machado, Sílvio M Zanata, Jesuí V Visentainer, Oscar de Oliveira Santos Junior, Marcelo M S Lima, Anete C Ferra. Fish oil improves anxiety-like, depressive-like and cognitive behaviors in olfactory bulbectomised rats. The European journal of neuroscience. vol 39. issue 2. 2014-09-03. PMID:24191918. |
in control rats, fo increased the hippocampal level of 5-ht and reduced that of 5-hiaa, indicating low 5-ht metabolism in this brain region. |
2014-09-03 |
2023-08-12 |
rat |
| Claudia Pudell, Bianca A Vicente, Ana M Delattre, Bruno Carabelli, Marco A Mori, Deborah Suchecki, Ricardo B Machado, Sílvio M Zanata, Jesuí V Visentainer, Oscar de Oliveira Santos Junior, Marcelo M S Lima, Anete C Ferra. Fish oil improves anxiety-like, depressive-like and cognitive behaviors in olfactory bulbectomised rats. The European journal of neuroscience. vol 39. issue 2. 2014-09-03. PMID:24191918. |
these results may be explained by increased levels of hippocampal bdnf and 5-ht, two major regulators of neuronal survival and long-term plasticity in this brain structure. |
2014-09-03 |
2023-08-12 |
rat |