| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kazuya Miyagawa, Minoru Tsuji, Hiroshi Taked. [Possible involvement of histone acetylation in the development of emotional resistance to stress stimuli]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 32. issue 5-6. 2013-11-01. PMID:23373313. |
in addition, dna microarray analysis showed that such a pretreatment with 5-ht(1a) receptor agonist produces changes in several gene transcriptions in the hippocampus including the reduction of histone deacetylase 10. |
2013-11-01 |
2023-08-12 |
mouse |
| Teresa F Burke, Tushar Advani, Megumi Adachi, Lisa M Monteggia, Julie G Hensle. Sensitivity of hippocampal 5-HT1A receptors to mild stress in BDNF-deficient mice. The international journal of neuropsychopharmacology. vol 16. issue 3. 2013-10-31. PMID:22575584. |
decreases in hippocampal 5-ht(1a) receptor function induced by mild stress in bdnf-deficient mice were prevented by administration of the selective serotonin reuptake inhibitor fluoxetine, which increased activation of trkb, the high affinity receptor for bdnf, in wild-type and bdnf(+/-) mice. |
2013-10-31 |
2023-08-12 |
mouse |
| Teresa F Burke, Tushar Advani, Megumi Adachi, Lisa M Monteggia, Julie G Hensle. Sensitivity of hippocampal 5-HT1A receptors to mild stress in BDNF-deficient mice. The international journal of neuropsychopharmacology. vol 16. issue 3. 2013-10-31. PMID:22575584. |
in hippocampal cultures, bdnf increased the capacity of 5-ht(1a) receptors to activate g proteins, an effect eliminated by the knockout of trkb, confirming trkb activation increases 5-ht(1a) receptor function. |
2013-10-31 |
2023-08-12 |
mouse |
| Teresa F Burke, Tushar Advani, Megumi Adachi, Lisa M Monteggia, Julie G Hensle. Sensitivity of hippocampal 5-HT1A receptors to mild stress in BDNF-deficient mice. The international journal of neuropsychopharmacology. vol 16. issue 3. 2013-10-31. PMID:22575584. |
the mechanisms underlying the sensitivity of hippocampal 5-ht(1a) receptors to mild stress and decreased bdnf expression remain to be elucidated and may have important implications for the emotional and cognitive impairments associated with stress-related mental illness. |
2013-10-31 |
2023-08-12 |
mouse |
| Shlomit Jacobson-Pick, Marie-Claude Audet, Robyn Jane McQuaid, Rahul Kalvapalle, Hymie Anisma. Social agonistic distress in male and female mice: changes of behavior and brain monoamine functioning in relation to acute and chronic challenges. PloS one. vol 8. issue 4. 2013-10-30. PMID:23565195. |
these treatments, like a stressor comprising physical restraint, increased plasma corticosterone and elicited variations of norepinephrine and serotonin levels and turnover within the prefrontal cortex, hippocampus and central amygdala. |
2013-10-30 |
2023-08-12 |
mouse |
| Yan Fan, Ping Chen, Ying Li, Meng-Yang Zh. Effects of chronic social defeat on expression of dopamine β-hydroxylase in rat brains. Synapse (New York, N.Y.). vol 67. issue 6. 2013-10-29. PMID:23389997. |
however, treatment with fluoxetine, an antidepressant with specific inhibition for serotonin transport, only selectively blocked increased dopamine β-hydroxylase protein levels in the hippocampus caused by csd. |
2013-10-29 |
2023-08-12 |
rat |
| Alvaro Llorente-Berzal, Carmen Manzanedo, Manuel Daza-Losada, Manuel Valero, Meritxell López-Gallardo, María A Aguilar, Marta Rodríguez-Arias, José Miñarro, Maria-Paz Vivero. Sex-dependent effects of early maternal deprivation on MDMA-induced conditioned place preference in adolescent rats: possible neurochemical correlates. Toxicology. vol 311. issue 1-2. 2013-10-25. PMID:23246480. |
animals were sacrificed on pnd 68-75 and levels of serotonin (5-ht) and its metabolite 5-hydroxyindole acetic acid were measured in the striatum, hippocampus and cortex, while the expression of hippocampal cb1 cannabinoid receptor (cb1r) and circulating levels of corticosterone and leptin were also measured. |
2013-10-25 |
2023-08-12 |
rat |
| Alvaro Llorente-Berzal, Carmen Manzanedo, Manuel Daza-Losada, Manuel Valero, Meritxell López-Gallardo, María A Aguilar, Marta Rodríguez-Arias, José Miñarro, Maria-Paz Vivero. Sex-dependent effects of early maternal deprivation on MDMA-induced conditioned place preference in adolescent rats: possible neurochemical correlates. Toxicology. vol 311. issue 1-2. 2013-10-25. PMID:23246480. |
a reduction in striatal and cortical 5-ht levels, increased expression of hippocampal cb1r and a marked trend towards higher circulating leptin levels were observed in mdma-treated md males. |
2013-10-25 |
2023-08-12 |
rat |
| Yuka Okada, Ken Tachibana, Shinya Yanagita, Ken Taked. Prenatal exposure to zinc oxide particles alters monoaminergic neurotransmitter levels in the brain of mouse offspring. The Journal of toxicological sciences. vol 38. issue 3. 2013-10-23. PMID:23665935. |
we also found changes of the levels of serotonin in the hypothalamus, and of the levels of 5-hiaa (5-ht metabolite) in the prefrontal cortex and hippocampus in the zno np-exposed group. |
2013-10-23 |
2023-08-12 |
mouse |
| Tushar Arora, Malay Bhowmik, Razia Khanam, Divya Vohor. Oxcarbazepine and fluoxetine protect against mouse models of obsessive compulsive disorder through modulation of cortical serotonin and CREB pathway. Behavioural brain research. vol 247. 2013-10-21. PMID:23473877. |
oxcarbazepine (oxc), a second generation antiepileptic drug, enhances hippocampal serotonin (5-ht) levels. |
2013-10-21 |
2023-08-12 |
mouse |
| Jennifer Do, Susan Schen. Self-administered MDMA produces dose- and time-dependent serotonin deficits in the rat brain. Addiction biology. vol 18. issue 3. 2013-10-17. PMID:21955305. |
in this study, tissue levels of 5ht in the frontal cortex, striatum and hippocampus were measured following different levels of self-administered mdma. |
2013-10-17 |
2023-08-12 |
rat |
| Franck Chenu, Mostafa El Mansari, Pierre Blie. Electrophysiological effects of repeated administration of agomelatine on the dopamine, norepinephrine, and serotonin systems in the rat brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 2. 2013-10-17. PMID:22871919. |
after 14 days, the administration of agomelatine induced an increase in: (1) the number of spontaneously active da neurons (p<0.05), (2) the bursting activity of da neurons (bursts/min, p<0.01 and percentage of spikes occurring in bursts, p<0.05), (3) the firing rate of drn-5-ht neurons (p<0.05), and (4) the tonic activation of postsynaptic 5-ht(1a) receptors located in the hippocampus. |
2013-10-17 |
2023-08-12 |
rat |
| Andrew E Arrant, Hikma Jemal, Cynthia M Kuh. Adolescent male rats are less sensitive than adults to the anxiogenic and serotonin-releasing effects of fenfluramine. Neuropharmacology. vol 65. 2013-10-17. PMID:23103347. |
adult rats had higher tissue serotonin content than adolescents in the prefrontal cortex, amygdala, and hippocampus, but the rate of serotonin synthesis was similar between age groups. |
2013-10-17 |
2023-08-12 |
rat |
| Monzurul Amin Roni, Shafiqur Rahma. Antidepressant-like effects of lobeline in mice: behavioral, neurochemical, and neuroendocrine evidence. Progress in neuro-psychopharmacology & biological psychiatry. vol 41. 2013-10-17. PMID:23200829. |
further, the effects of lobeline on fss-induced increased in norepinephrine (ne) and serotonin levels in the prefrontal cortex (pfc) and hippocampus were determined using high performance liquid chromatography. |
2013-10-17 |
2023-08-12 |
mouse |
| Karen L Smith, Gemma K Ford, David S Jessop, David P Fin. Behavioural, neurochemical and neuroendocrine effects of the endogenous β-carboline harmane in fear-conditioned rats. Journal of psychopharmacology (Oxford, England). vol 27. issue 2. 2013-09-30. PMID:23015542. |
harmane increased plasma acth and corticosterone concentrations, and serotonin (in hypothalamus, amygdaloid cortex, prefrontal cortex and hippocampus) and noradrenaline (prefrontal cortex) content, irrespective of fear-conditioning. |
2013-09-30 |
2023-08-12 |
rat |
| Li Hu, Jia Liang, Shu-Ying Jin, Yan-Jing Han, Jun Lu, Ya T. [Progress of researches on mechanisms of acupuncture underlying improvement of depression in the past five years]. Zhen ci yan jiu = Acupuncture research. vol 38. issue 3. 2013-09-24. PMID:24006675. |
in the present paper, the authors summarize mechanisms of acupuncture for depression from 1) upregulating levels of monoamine neurotransmitters, gamma-aminobutyric acid, 5-ht, receptor binding, and hypothalamic neuropeptide y, beta-endorphine, and mu-receptor expression, and down-regulating hippocampal glutamate content, etc. |
2013-09-24 |
2023-08-12 |
Not clear |
| M Embree, V Michopoulos, J R Votaw, R J Voll, J Mun, J S Stehouwer, M M Goodman, M E Wilson, M M Sánche. The relation of developmental changes in brain serotonin transporter (5HTT) and 5HT1A receptor binding to emotional behavior in female rhesus monkeys: effects of social status and 5HTT genotype. Neuroscience. vol 228. 2013-09-23. PMID:23079633. |
the increase in 5ht1a bp(nd) in these socially housed female rhesus monkeys is a robust finding, occurring across all groups, regardless of social status or 5htt genotype, and occurring in the left and right hemispheres of all prefrontal regions studied, as well as the amygdala, hippocampus, hypothalamus, and raphe nuclei. |
2013-09-23 |
2023-08-12 |
human |
| A Akubuiro, M Bridget Zimmerman, L L Boles Ponto, S A Walsh, J Sunderland, L McCormick, M Sing. Hyperactive hypothalamus, motivated and non-distractible chronic overeating in ADAR2 transgenic mice. Genes, brain, and behavior. vol 12. issue 3. 2013-09-23. PMID:23323881. |
the results indicate that adar2 transgenic mice exhibit, (1) a food preference for diets with higher fat content, (2) significantly increased food intake that is non-distractible in a competing reward environment, (3) significantly increased messenger rna (mrna) expressions of adar2, serotonin 2c receptor (5ht2c r), d1, d2 and mu opioid receptors and no change in corticotropin-releasing hormone mrnas and significantly reduced adar2 protein expression in the hypothalamus, (4) significantly increased d1 receptor and altered bioamines with no change in adar2, mu opioid and d2 receptor mrna expression in the striatum and (5) significantly greater glucose metabolism in the hypothalamus, brain stem, right hippocampus, left and right mid brain regions and suprascapular peripheral tissue than controls. |
2013-09-23 |
2023-08-12 |
mouse |
| Yi Liu, Genguang Jia, Lingshan Gou, Lingyan Sun, Xiaobin Fu, Nuo Lan, Sai Li, Xiaoxing Yi. Antidepressant-like effects of tea polyphenols on mouse model of chronic unpredictable mild stress. Pharmacology, biochemistry, and behavior. vol 104. 2013-09-17. PMID:23290936. |
our results showed that cums significantly decreased the levels of serum serotonin (5-ht) and norepinephrine (ne) in the hippocampus, the prefrontal cortex and serum, and the activities of superoxide dismutase (sod) and catalase (cat), with an increase in lipid peroxidation level as well as a reduction in glutathione (gsh) level and an elevation in the production of malondialdehyde (mda) in the hippocampus and the prefrontal cortex. |
2013-09-17 |
2023-08-12 |
mouse |
| Jana Tchekalarova, Zlatina Petkova, Daniela Pechlivanova, Slavianka Moyanova, Lidia Kortenska, Rumiana Mitreva, Valentin Lozanov, Dimitrina Atanasova, Nikolai Lazarov, Alexander Stoyne. Prophylactic treatment with melatonin after status epilepticus: effects on epileptogenesis, neuronal damage, and behavioral changes in a kainate model of temporal lobe epilepsy. Epilepsy & behavior : E&B. vol 27. issue 1. 2013-09-12. PMID:23435277. |
melatonin reduced the neuronal damage in the ca1 area of the hippocampus and piriform cortex and recovered the decrease of hippocampal serotonin (5-ht) level in rats with epilepsy. |
2013-09-12 |
2023-08-12 |
rat |