| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yingcong Yu, Shujuan Wu, Jianxin Li, Renye Wang, Xupei Xie, Xuefeng Yu, Jianchun Pan, Ying Xu, Liang Zhen. The effect of curcumin on the brain-gut axis in rat model of irritable bowel syndrome: involvement of 5-HT-dependent signaling. Metabolic brain disease. vol 30. issue 1. 2016-03-17. PMID:24807589. |
moreover, curcumin increased serotonin, bdnf and pcreb levels in the hippocampus, but they were decreased in the colonic of cas rats. |
2016-03-17 |
2023-08-13 |
rat |
| Jianliang Chen, Dan Lin, Chong Zhang, Gaowen Li, Nianping Zhang, Lina Ruan, Qizhi Yan, Jianxin Li, Xuefeng Yu, Xupei Xie, Cong Pang, Liang Cao, Jianchun Pan, Ying X. Antidepressant-like effects of ferulic acid: involvement of serotonergic and norepinergic systems. Metabolic brain disease. vol 30. issue 1. 2016-03-17. PMID:25483788. |
the current study provides the first lines of evidence that serotonin and norepinephrine, but not dopamine levels were elevated in mouse hippocampus and frontal cortex after ferulic acid treatment. |
2016-03-17 |
2023-08-13 |
mouse |
| C Norman. Towards a new model for cellular pathophysiology in affective disorder. Acta neuropsychiatrica. vol 12. issue 3. 2016-03-16. PMID:26975257. |
we tested the modulation of hippocampal long-term plasticity, a model for learning and memory, by 5-ht and found a selective impairment of long-term depression resulting in a positive modification of synaptic network properties. |
2016-03-16 |
2023-08-13 |
Not clear |
| Hyun-Ja Jeong, Jeong-Hwa Kim, Na-Rae Kim, Myoung-schook Yoou, Sun-Young Nam, Kyu-Youb Kim, Youngjin Choi, Jae-Bum Jang, In-Cheol Kang, Nam-In Baek, Hyung-Min Ki. Antidepressant effect of Stillen. Archives of pharmacal research. vol 38. issue 6. 2016-03-08. PMID:25163682. |
in the stillen-administered group, increased levels of 5-hydroxytryptamine (serotonin) and brain-derived neurotrophic factor protein were observed in the hippocampus. |
2016-03-08 |
2023-08-13 |
mouse |
| Lingpeng Zhu, Tingting Wei, Jing Gao, Xiayun Chang, He He, Mingxing Miao, Tianhua Ya. Salidroside attenuates lipopolysaccharide (LPS) induced serum cytokines and depressive-like behavior in mice. Neuroscience letters. vol 606. 2016-03-01. PMID:26300543. |
levels of neurotransmitters like norepinephrine (ne) and 5-hydroxytryptamine (5-ht) in the prefrontal cortex were detected by hplc-ms. further, brain-derived neurotrophic factor (bdnf), tropomyosin-related kinase b (trkb) and nuclear factor-κb (nf-κb) in hippocampal was determined by western blot analysis. |
2016-03-01 |
2023-08-13 |
mouse |
| A M Depin. Early prenatal exposure to LPS results in anxiety- and depression-related behaviors in adulthood. Neuroscience. vol 299. 2016-02-29. PMID:25943476. |
in addition, lps mice had reduced serotonin and noradrenaline levels in the hippocampus and diminished reelin immunoreactivity in the dentate gyrus, while their adult hippocampal neurogenesis was not affected. |
2016-02-29 |
2023-08-13 |
mouse |
| Mansour A Al-Hazmi, Sayed M Rawi, Nadia Ms Arafa, Abeer Wagas, Ayat Os Montasse. The potent effects of ginseng root extract and memantine on cognitive dysfunction in male albino rats. Toxicology and industrial health. vol 31. issue 6. 2016-02-18. PMID:23406953. |
scopolamine (2 mg/kg ip) group showed significant increase in ache reactivity and glutamate level and reduced monoamines (norepinephrine, dopamine and serotonin) and γ-aminobutyric acid contents in cortex, hippocampus and striatum. |
2016-02-18 |
2023-08-12 |
rat |
| Linda Booij, Moshe Szyf, Angela Carballedo, Eva-Maria Frey, Derek Morris, Sergiy Dymov, Farida Vaisheva, Victoria Ly, Ciara Fahey, James Meaney, Michael Gill, Thomas Frod. DNA methylation of the serotonin transporter gene in peripheral cells and stress-related changes in hippocampal volume: a study in depressed patients and healthy controls. PloS one. vol 10. issue 3. 2016-02-11. PMID:25781010. |
dna methylation of the serotonin transporter gene in peripheral cells and stress-related changes in hippocampal volume: a study in depressed patients and healthy controls. |
2016-02-11 |
2023-08-13 |
Not clear |
| Linda Booij, Moshe Szyf, Angela Carballedo, Eva-Maria Frey, Derek Morris, Sergiy Dymov, Farida Vaisheva, Victoria Ly, Ciara Fahey, James Meaney, Michael Gill, Thomas Frod. DNA methylation of the serotonin transporter gene in peripheral cells and stress-related changes in hippocampal volume: a study in depressed patients and healthy controls. PloS one. vol 10. issue 3. 2016-02-11. PMID:25781010. |
the aim of this study was to test whether greater dna methylation in specific cpg sites at the serotonin transporter promoter in peripheral cells is associated with childhood trauma, depression, and smaller hippocampal volume. |
2016-02-11 |
2023-08-13 |
Not clear |
| Linda Booij, Moshe Szyf, Angela Carballedo, Eva-Maria Frey, Derek Morris, Sergiy Dymov, Farida Vaisheva, Victoria Ly, Ciara Fahey, James Meaney, Michael Gill, Thomas Frod. DNA methylation of the serotonin transporter gene in peripheral cells and stress-related changes in hippocampal volume: a study in depressed patients and healthy controls. PloS one. vol 10. issue 3. 2016-02-11. PMID:25781010. |
childhood trauma, being male, and smaller hippocampal volume were independently associated with greater peripheral serotonin transporter methylation. |
2016-02-11 |
2023-08-13 |
Not clear |
| Robert Blum, Klaus-Peter Lesc. Parkinson's disease, anxious depression and serotonin--zooming in on hippocampal neurogenesis. Journal of neurochemistry. vol 135. issue 3. 2016-02-11. PMID:26382574. |
parkinson's disease, anxious depression and serotonin--zooming in on hippocampal neurogenesis. |
2016-02-11 |
2023-08-13 |
Not clear |
| Janina Deusser, Stefanie Schmidt, Benjamin Ettle, Sonja Plötz, Sabine Huber, Christian P Müller, Eliezer Masliah, Jürgen Winkler, Zacharias Koh. Serotonergic dysfunction in the A53T alpha-synuclein mouse model of Parkinson's disease. Journal of neurochemistry. vol 135. issue 3. 2016-02-10. PMID:26201615. |
a loss of serotonergic neurons or their projections into the hippocampus and alterations in serotonin release may be linked to these symptoms. |
2016-02-10 |
2023-08-13 |
mouse |
| Shu-Juan Wu, Ren-Ye Wang, Ji-Xiong Xue, Jian-Chun Pa. [Effect of piperine on 5-HT and synaptophysin expression of rats with irritable bowel syndrome]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 48. issue 12. 2016-02-02. PMID:24689235. |
the expressions of 5-ht and synaptophysin in the hippocampus and colon were determined by high performance liquid chromatography (hplc) and western blotting, respectively. |
2016-02-02 |
2023-08-12 |
rat |
| Shu-Juan Wu, Ren-Ye Wang, Ji-Xiong Xue, Jian-Chun Pa. [Effect of piperine on 5-HT and synaptophysin expression of rats with irritable bowel syndrome]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 48. issue 12. 2016-02-02. PMID:24689235. |
as compared with those in the normal control group, the expression of 5-ht significantly decreased, 5-hiaa/5-ht ratio significantly increased in the hippocampus of ibs model group (p<0.05), but opposite presentations were noted in the colon (p<0.05). |
2016-02-02 |
2023-08-12 |
rat |
| Shu-Juan Wu, Ren-Ye Wang, Ji-Xiong Xue, Jian-Chun Pa. [Effect of piperine on 5-HT and synaptophysin expression of rats with irritable bowel syndrome]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 48. issue 12. 2016-02-02. PMID:24689235. |
piperine improved the behavior of ibs rats, and reversed the levels of 5-ht and 5-hiaa, and 5-hiaa/5-ht proportion in the hippocampus and colon (p<0.05); besides, they significantly reverse the synaptophysin level in the hippocampus and colon (p<0.05). |
2016-02-02 |
2023-08-12 |
rat |
| E J Connors, M M Migliore, S L Pillsbury, A N Shaik, A C Kentne. Environmental enrichment models a naturalistic form of maternal separation and shapes the anxiety response patterns of offspring. Psychoneuroendocrinology. vol 52. 2016-01-29. PMID:25437120. |
serotonin, corticosterone, gaba, glutamate) in prefrontal cortex and hippocampus as a function of ee, communal nesting (cn) and standard care (sc). |
2016-01-29 |
2023-08-13 |
rat |
| Antonios Stamatakis, Theodora Kalpachidou, Androniki Raftogianni, Efstratia Zografou, Athanasia Tzanou, Stavroula Pondiki, Fotini Stylianopoulo. Rat dams exposed repeatedly to a daily brief separation from the pups exhibit increased maternal behavior, decreased anxiety and altered levels of receptors for estrogens (ERα, ERβ), oxytocin and serotonin (5-HT1A) in their brain. Psychoneuroendocrinology. vol 52. 2016-01-29. PMID:25486578. |
on postnatal days (pnd) 12 and 22, we determined in experimental and control dams levels of anxiety in the elevated plus maze (epm) as well as the levels of receptors for estrogens (erα, erβ), oxytocin (otr) and serotonin (5-ht1ar) in areas of the limbic system (prefrontal cortex-pfc, hippocampus, lateral septum-sl, medial preoptic area-mpoa, shell of nucleus accumbens-nac-sh, central-cea and basolateral-bla amygdala), involved in the regulation of maternal behavior. |
2016-01-29 |
2023-08-13 |
rat |
| Yongjun Xu, Hui Sheng, Zhiping Tang, Jianqiang Lu, Xin N. Inflammation and increased IDO in hippocampus contribute to depression-like behavior induced by estrogen deficiency. Behavioural brain research. vol 288. 2016-01-27. PMID:25907742. |
the results showed that ovariectomy resulted in depression-like behavior in female rats and caused a decrease in 5-ht content and an increase in levels of ido, ifn-γ, il-6, toll like receptor (tlr)-4 and phosphorylated nf-κb (p65 subunit) in hippocampus but not in prefrontal cortex (pfc). |
2016-01-27 |
2023-08-13 |
rat |
| Yongjun Xu, Hui Sheng, Zhiping Tang, Jianqiang Lu, Xin N. Inflammation and increased IDO in hippocampus contribute to depression-like behavior induced by estrogen deficiency. Behavioural brain research. vol 288. 2016-01-27. PMID:25907742. |
our study suggests that estrogen inhibits inflammation and activates of ido and maintains 5-ht level in hippocampus, thereby ameliorating depression-like behavior. |
2016-01-27 |
2023-08-13 |
rat |
| Yuki Imoto, Toshihiko Kira, Mamiko Sukeno, Naoya Nishitani, Kazuki Nagayasu, Takayuki Nakagawa, Shuji Kaneko, Katsunori Kobayashi, Eri Segi-Nishid. Role of the 5-HT4 receptor in chronic fluoxetine treatment-induced neurogenic activity and granule cell dematuration in the dentate gyrus. Molecular brain. vol 8. 2016-01-19. PMID:25976618. |
chronic treatment with selective serotonin (5-ht) reuptake inhibitors (ssris) facilitates adult neurogenesis and reverses the state of maturation in mature granule cells (gcs) in the dentate gyrus (dg) of the hippocampus. |
2016-01-19 |
2023-08-13 |
Not clear |