| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gaël Quesseveur, Benjamin Portal, Jean-Arnaud Basile, Pascal Ezan, Alexia Mathou, Hélène Halley, Corinne Leloup, Xavier Fioramonti, Nicole Déglon, Christian Giaume, Claire Rampon, Bruno P Guiar. Attenuated Levels of Hippocampal Connexin 43 and its Phosphorylation Correlate with Antidepressant- and Anxiolytic-Like Activities in Mice. Frontiers in cellular neuroscience. vol 9. 2016-01-06. PMID:26733815. |
conversely, the expression of cx43 was assessed in the hippocampus of mice subjected to prolonged corticosterone (cort) exposure, given either alone or in combination with an antidepressant drug, the selective serotonin reuptake inhibitor fluoxetine. |
2016-01-06 |
2023-08-13 |
mouse |
| Yann S Mineur, Emily B Einstein, Matthew P Bentham, Mattis B Wigestrand, Sam Blakeman, Sylvia A Newbold, Marina R Picciott. Expression of the 5-HT1A serotonin receptor in the hippocampus is required for social stress resilience and the antidepressant-like effects induced by the nicotinic partial agonist cytisine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 4. 2016-01-05. PMID:25288485. |
this study suggests that serotonin signaling through postsynaptic 5-ht1a receptors in the hippocampus is critical for the antidepressant-like effects of a cholinergic drug and begins to elucidate the molecular mechanisms underlying interactions between the serotonergic and cholinergic systems related to mood disorders. |
2016-01-05 |
2023-08-13 |
mouse |
| Ling-Na Han, Li Zhang, Li-Bo Li, Yi-Na Sun, Yong Wang, Li Chen, Yuan Guo, Yu-Ming Zhang, Qiao-Jun Zhang, Jian Li. Activation of serotonin(2C) receptors in the lateral habenular nucleus increases the expression of depression-related behaviors in the hemiparkinsonian rat. Neuropharmacology. vol 93. 2016-01-01. PMID:25661701. |
intra-lhb injection of ro60-0175 decreased dopamine, 5-ht and noradrenaline levels in the medial prefrontal cortex, habenula, hippocampus and amygdala in sham-operated and the lesioned rats. |
2016-01-01 |
2023-08-13 |
rat |
| Sarahi Lopez-Esparza, Laura C Berumen, Karla Padilla, Ricardo Miledi, Guadalupe García-Alcoce. Expression of hippocampal serotonin receptors 5-HT2C and 5-HT5A in a rat model of diet-induced obesity supplemented with tryptophan. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 42. 2015-12-30. PMID:25720309. |
expression of hippocampal serotonin receptors 5-ht2c and 5-ht5a in a rat model of diet-induced obesity supplemented with tryptophan. |
2015-12-30 |
2023-08-13 |
rat |
| Hai-Juan Li, Rui-Yun Peng, Chang-Zhen Wang, Si-Mo Qiao, Zou Yong, Ya-Bing Gao, Xin-Ping Xu, Shao-Xia Wang, Ji Dong, Hong-Yan Zuo, Zhao Li, Hong-Mei Zhou, Li-Feng Wang, Xiang-Jun H. Alterations of cognitive function and 5-HT system in rats after long term microwave exposure. Physiology & behavior. vol 140. 2015-12-28. PMID:25542888. |
we demonstrated that chronic exposure to microwave (2.856ghz, with the average power density of 5, 10, 20 and 30mw/cm(2)) could induce dose-dependent deficit of spatial learning and memory in rats accompanied with inhibition of brain electrical activity, the degeneration of hippocampus neurons, and the disturbance of neurotransmitters, among which the increase of 5-ht occurred as the main long-term change that the decrease of its metabolism partly contributed to. |
2015-12-28 |
2023-08-13 |
rat |
| Mónica Morais, Paulo A R Santos, António Mateus-Pinheiro, Patrícia Patrício, Luísa Pinto, Nuno Sousa, Pedro Pedroso, Susana Almeida, Augusto Filipe, João M Bess. The effects of chronic stress on hippocampal adult neurogenesis and dendritic plasticity are reversed by selective MAO-A inhibition. Journal of psychopharmacology (Oxford, England). vol 28. issue 12. 2015-12-23. PMID:25315831. |
in the present study, adult neurogenesis and neuronal morphology were examined in the hippocampus of rats exposed to chronic mild stress (cms) and treated with the selective reversible mao-a inhibitor (rima) drug, pirlindole and the selective serotonin reuptake inhibitor (ssri), fluoxetine. |
2015-12-23 |
2023-08-13 |
rat |
| Yifat Glikmann-Johnston, Michael M Saling, David C Reutens, Julie C Stou. Hippocampal 5-HT1A Receptor and Spatial Learning and Memory. Frontiers in pharmacology. vol 6. 2015-12-23. PMID:26696889. |
the hippocampus, which has a central role in spatial cognition, is characterized by high concentration of serotonin (5-hydroxytryptamine; 5-ht) receptor binding sites, particularly of the 1a receptor (5-ht1a) subtype. |
2015-12-23 |
2023-08-13 |
mouse |
| Wan-wan Liu, Lu Xu, Xian-zhe Dong, Xiao Tan, Shi Wang, Wei-yu Zhu, Ping Li. [Effects of Kaixin San formulas on behavioristics and central monoamine neurotransmitters of chronic stress rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 40. issue 11. 2015-12-17. PMID:26552177. |
the classic isolation method and the chronic unpredictable mild stress (cums) depression model were combined to investigate the changes in contents in hippocampus and monoamine neurotransmitters (ne, da, 5-ht) and the components of some formulas in plasma with hplc and uplc-q-tof-mse methods. |
2015-12-17 |
2023-08-13 |
rat |
| Wan-wan Liu, Lu Xu, Xian-zhe Dong, Xiao Tan, Shi Wang, Wei-yu Zhu, Ping Li. [Effects of Kaixin San formulas on behavioristics and central monoamine neurotransmitters of chronic stress rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 40. issue 11. 2015-12-17. PMID:26552177. |
as a result, dingzhi xiaowan recorded in essential recipes for emergent use worth a thousand significantly increased the behavioral scores, ne and 5-ht contents in hippocampus and ne, da and 5-ht contents in cortex, with the best anti-depressant effect. |
2015-12-17 |
2023-08-13 |
rat |
| Wan-wan Liu, Lu Xu, Xian-zhe Dong, Xiao Tan, Shi Wang, Wei-yu Zhu, Ping Li. [Effects of Kaixin San formulas on behavioristics and central monoamine neurotransmitters of chronic stress rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 40. issue 11. 2015-12-17. PMID:26552177. |
dingzhi xiaowan recorded in complete records of ancient and modern medical works showed a notable increase in sucrose preference and open field score in model rats, ne content in hippocampus and ne, da and 5-ht contents in cortex, with a certain anti anti-depressant effect. |
2015-12-17 |
2023-08-13 |
rat |
| Wan-wan Liu, Lu Xu, Xian-zhe Dong, Xiao Tan, Shi Wang, Wei-yu Zhu, Ping Li. [Effects of Kaixin San formulas on behavioristics and central monoamine neurotransmitters of chronic stress rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 40. issue 11. 2015-12-17. PMID:26552177. |
puxin decoction recorded in a supplement to recipes worth a thousand gold showed 5-ht content in hippocampus and da content in cortex. |
2015-12-17 |
2023-08-13 |
rat |
| Yoshihiro Oyamada, Masakuni Horiguchi, Lakshmi Rajagopal, Masanori Miyauchi, Herbert Y Meltze. Combined serotonin (5-HT)1A agonism, 5-HT(2A) and dopamine D₂ receptor antagonism reproduces atypical antipsychotic drug effects on phencyclidine-impaired novel object recognition in rats. Behavioural brain research. vol 285. 2015-12-14. PMID:25448429. |
most atypical, but not typical apds, are more potent 5-ht(2a) receptor inverse agonists than dopamine (da) d2 antagonists, and have been shown to enhance cortical and hippocampal efflux and to be direct or indirect 5-ht(1a) agonists in vivo. |
2015-12-14 |
2023-08-13 |
rat |
| Yuki Ota, Yukio Ago, Tatsunori Tanaka, Shigeru Hasebe, Yui Toratani, Yusuke Onaka, Hitoshi Hashimoto, Kazuhiro Takuma, Toshio Matsud. Anxiolytic-like effects of restraint during the dark cycle in adolescent mice. Behavioural brain research. vol 284. 2015-12-07. PMID:25687845. |
the light cycle stress increased plasma corticosterone levels, and elevated c-fos expression in the prefrontal cortex, paraventricular hypothalamic nucleus, basolateral amygdala and dentate gyrus, and enhanced serotonin turnover in the hippocampus and striatum, while the dark cycle stress did not. |
2015-12-07 |
2023-08-13 |
mouse |
| Natascha C da Fonseca, Helena P G Joaquim, Leda L Talib, Silvia de Vincentiis, Wagner F Gattaz, Kette D Valent. Hippocampal serotonin depletion is related to the presence of generalized tonic-clonic seizures, but not to psychiatric disorders in patients with temporal lobe epilepsy. Epilepsy research. vol 111. 2015-12-01. PMID:25769369. |
hippocampal serotonin depletion is related to the presence of generalized tonic-clonic seizures, but not to psychiatric disorders in patients with temporal lobe epilepsy. |
2015-12-01 |
2023-08-13 |
Not clear |
| Natascha C da Fonseca, Helena P G Joaquim, Leda L Talib, Silvia de Vincentiis, Wagner F Gattaz, Kette D Valent. Hippocampal serotonin depletion is related to the presence of generalized tonic-clonic seizures, but not to psychiatric disorders in patients with temporal lobe epilepsy. Epilepsy research. vol 111. 2015-12-01. PMID:25769369. |
in this work, we measured [5-ht]s in hippocampal tissues from a large series of patients with refractory temporal lobe epilepsy caused by hippocampal sclerosis who underwent epilepsy surgery and evaluated the relationship between [5ht] and epilepsy-related clinical variables and psychiatric disorders. |
2015-12-01 |
2023-08-13 |
Not clear |
| Benjamin D Sachs, Marc G Caro. Chronic fluoxetine increases extra-hippocampal neurogenesis in adult mice. The international journal of neuropsychopharmacology. vol 18. issue 4. 2015-11-20. PMID:25583694. |
although this effect was initially reported to be restricted to the hippocampus, recent work has suggested that fluoxetine, a selective serotonin reuptake inhibitor, also promotes neurogenesis in the cortex. |
2015-11-20 |
2023-08-13 |
mouse |
| J Jesús Hernández-Pérez, Blanca E Gutiérrez-Guzmán, Miguel Á López-Vázquez, María E Olvera-Corté. Supramammillary serotonin reduction alters place learning and concomitant hippocampal, septal, and supramammillar theta activity in a Morris water maze. Frontiers in pharmacology. vol 6. 2015-11-20. PMID:26578960. |
supramammillary serotonin reduction alters place learning and concomitant hippocampal, septal, and supramammillar theta activity in a morris water maze. |
2015-11-20 |
2023-08-13 |
rat |
| J Jesús Hernández-Pérez, Blanca E Gutiérrez-Guzmán, Miguel Á López-Vázquez, María E Olvera-Corté. Supramammillary serotonin reduction alters place learning and concomitant hippocampal, septal, and supramammillar theta activity in a Morris water maze. Frontiers in pharmacology. vol 6. 2015-11-20. PMID:26578960. |
serotonin desynchronizes hippocampal theta activity, and it has been proposed that serotonin may regulate learning through the modulation of hippocampal synchrony. |
2015-11-20 |
2023-08-13 |
rat |
| J Jesús Hernández-Pérez, Blanca E Gutiérrez-Guzmán, Miguel Á López-Vázquez, María E Olvera-Corté. Supramammillary serotonin reduction alters place learning and concomitant hippocampal, septal, and supramammillar theta activity in a Morris water maze. Frontiers in pharmacology. vol 6. 2015-11-20. PMID:26578960. |
because it has been reported that sumn inactivation with lidocaine impairs the consolidation of reference memory, we asked whether changes in hippocampal theta activity related to learning would occur through serotonin depletion in the sumn, together with deficiencies in memory. |
2015-11-20 |
2023-08-13 |
rat |
| J Jesús Hernández-Pérez, Blanca E Gutiérrez-Guzmán, Miguel Á López-Vázquez, María E Olvera-Corté. Supramammillary serotonin reduction alters place learning and concomitant hippocampal, septal, and supramammillar theta activity in a Morris water maze. Frontiers in pharmacology. vol 6. 2015-11-20. PMID:26578960. |
serotonin depletion in the sumn induced deficient spatial learning and altered the expression of hippocampal high-frequency theta activity. |
2015-11-20 |
2023-08-13 |
rat |