| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Bétry, D Overstreet, N Haddjeri, A L Pehrson, C Bundgaard, C Sanchez, A Mør. A 5-HT3 receptor antagonist potentiates the behavioral, neurochemical and electrophysiological actions of an SSRI antidepressant. Pharmacology, biochemistry, and behavior. vol 131. 2016-01-15. PMID:25697477. |
effects of s.c. administration of the compounds alone and in combination on extracellular levels of 5-ht were assessed in the ventral hippocampus of freely moving rats by microdialysis. |
2016-01-15 |
2023-08-13 |
rat |
| C Bétry, D Overstreet, N Haddjeri, A L Pehrson, C Bundgaard, C Sanchez, A Mør. A 5-HT3 receptor antagonist potentiates the behavioral, neurochemical and electrophysiological actions of an SSRI antidepressant. Pharmacology, biochemistry, and behavior. vol 131. 2016-01-15. PMID:25697477. |
it partially prevented the suppressant effect of paroxetine on drn 5-ht neuronal firing and enhanced the paroxetine-induced increase of hippocampal extracellular 5-ht release. |
2016-01-15 |
2023-08-13 |
rat |
| Momen W Alhaj, Sawsan A Zaitone, Yasser M Moustaf. Fluvoxamine alleviates seizure activity and downregulates hippocampal GAP-43 expression in pentylenetetrazole-kindled mice: role of 5-HT3 receptors. Behavioural pharmacology. vol 26. issue 4. 2016-01-13. PMID:25590967. |
repeated administration of fluvoxamine (20 mg/kg) in ptz-kindled mice suppressed seizure scores, protected against hippocampal neuronal loss, and downregulated gap-43 expression, without producing any signs of the 5-ht syndrome in healthy rats. |
2016-01-13 |
2023-08-13 |
mouse |
| F Sarubbo, M R Ramis, S Aparicio, L Ruiz, S Esteban, A Miralles, D Morant. Improving effect of chronic resveratrol treatment on central monoamine synthesis and cognition in aged rats. Age (Dordrecht, Netherlands). vol 37. issue 3. 2016-01-13. PMID:25895558. |
the resveratrol treatment enhances serotonin (5-ht) levels in pineal gland, in hippocampus, and in striatum, and those of noradrenaline (na) in hippocampus and also dopamine (da) in striatum. |
2016-01-13 |
2023-08-13 |
rat |
| Jana Tchekalarova, Ellen Loyens, Ilse Smolder. Effects of AT1 receptor antagonism on kainate-induced seizures and concomitant changes in hippocampal extracellular noradrenaline, serotonin, and dopamine levels in Wistar-Kyoto and spontaneously hypertensive rats. Epilepsy & behavior : E&B. vol 46. 2016-01-13. PMID:25922088. |
effects of at1 receptor antagonism on kainate-induced seizures and concomitant changes in hippocampal extracellular noradrenaline, serotonin, and dopamine levels in wistar-kyoto and spontaneously hypertensive rats. |
2016-01-13 |
2023-08-13 |
rat |
| Jana Tchekalarova, Ellen Loyens, Ilse Smolder. Effects of AT1 receptor antagonism on kainate-induced seizures and concomitant changes in hippocampal extracellular noradrenaline, serotonin, and dopamine levels in Wistar-Kyoto and spontaneously hypertensive rats. Epilepsy & behavior : E&B. vol 46. 2016-01-13. PMID:25922088. |
the present study aimed to assess the effects of the selective at1 receptor antagonist zd7155 on kainic acid (ka)-induced status epilepticus (se) development and accompanying changes in the hippocampal extracellular (ec) neurotransmitter levels of noradrenaline (nad), serotonin (5-ht), and dopamine (da) in spontaneously hypertensive rats (shrs) and their parent strain wistar-kyoto (wky) rats, since monoamines are well-known neurotransmitters involved in mechanisms of both epilepsy and hypertension. |
2016-01-13 |
2023-08-13 |
rat |
| Jana Tchekalarova, Ellen Loyens, Ilse Smolder. Effects of AT1 receptor antagonism on kainate-induced seizures and concomitant changes in hippocampal extracellular noradrenaline, serotonin, and dopamine levels in Wistar-Kyoto and spontaneously hypertensive rats. Epilepsy & behavior : E&B. vol 46. 2016-01-13. PMID:25922088. |
in vivo microdialysis demonstrated significant ka-induced increases of the hippocampal nad and da levels in shrs and of nad, 5-ht, and da in wky rats. |
2016-01-13 |
2023-08-13 |
rat |
| Jana Tchekalarova, Ellen Loyens, Ilse Smolder. Effects of AT1 receptor antagonism on kainate-induced seizures and concomitant changes in hippocampal extracellular noradrenaline, serotonin, and dopamine levels in Wistar-Kyoto and spontaneously hypertensive rats. Epilepsy & behavior : E&B. vol 46. 2016-01-13. PMID:25922088. |
these results suggest a lack of direct relationship between ka-induced seizure susceptibility and adaptive changes of hippocampal nad, 5-ht, and da levels in the effects of zd7155 in wky rats and shrs. |
2016-01-13 |
2023-08-13 |
rat |
| Saroj Kumar Das, Kalpana Barhwal, Sunil Kumar Hota, Mahendra Kumar Thakur, Ravi Bihari Srivastav. Disrupting monotony during social isolation stress prevents early development of anxiety and depression like traits in male rats. BMC neuroscience. vol 16. 2016-01-12. PMID:25880744. |
hippocampal serotonin and 5-hydroxy indole acetic acid (5-hiaa) levels were estimated along with the expression of phospho-insulin like growth factor-1 receptor (pigf-1r) and phospho cyclic amp response-element binding protein (pcreb). |
2016-01-12 |
2023-08-13 |
rat |
| M Kusek, J Sowa, K Tokarski, G Hes. Impaired effect of activation of rat hippocampal 5-HT7 receptors, induced by treatment with the 5-HT7 receptor antagonist SB 269970. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 66. issue 2. 2016-01-12. PMID:25903960. |
effects of the 5-ht(7) receptor antagonist sb 269970, administered for 14 days (1.25 mg/kg), were studied in ex vivo slices of rat hippocampus. |
2016-01-12 |
2023-08-13 |
rat |
| M Kusek, J Sowa, K Tokarski, G Hes. Impaired effect of activation of rat hippocampal 5-HT7 receptors, induced by treatment with the 5-HT7 receptor antagonist SB 269970. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 66. issue 2. 2016-01-12. PMID:25903960. |
these data demonstrate that repeated administration of sb 269970 impairs the reactivity of the ca1 hippocampal neuronal network to 5-ht(7) receptor activation. |
2016-01-12 |
2023-08-13 |
rat |
| Iffat Ara, Samina Ban. Serotonergic activity and hypothalamic-pituitary-adrenal axis response in alcohol administered and subsequently withdrawn rats. Pakistan journal of pharmaceutical sciences. vol 28. issue 4. 2016-01-11. PMID:26142516. |
data analysis showed that there was significant increase in tryptophan (hippocampus), 5-ht (hippocampus and amygdala) and 5-ht turnover in all the three regions examined when alcohol administered rats were compared with matched controls. |
2016-01-11 |
2023-08-13 |
rat |
| Gaël Quesseveur, Benjamin Portal, Jean-Arnaud Basile, Pascal Ezan, Alexia Mathou, Hélène Halley, Corinne Leloup, Xavier Fioramonti, Nicole Déglon, Christian Giaume, Claire Rampon, Bruno P Guiar. Attenuated Levels of Hippocampal Connexin 43 and its Phosphorylation Correlate with Antidepressant- and Anxiolytic-Like Activities in Mice. Frontiers in cellular neuroscience. vol 9. 2016-01-06. PMID:26733815. |
conversely, the expression of cx43 was assessed in the hippocampus of mice subjected to prolonged corticosterone (cort) exposure, given either alone or in combination with an antidepressant drug, the selective serotonin reuptake inhibitor fluoxetine. |
2016-01-06 |
2023-08-13 |
mouse |
| Yann S Mineur, Emily B Einstein, Matthew P Bentham, Mattis B Wigestrand, Sam Blakeman, Sylvia A Newbold, Marina R Picciott. Expression of the 5-HT1A serotonin receptor in the hippocampus is required for social stress resilience and the antidepressant-like effects induced by the nicotinic partial agonist cytisine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 4. 2016-01-05. PMID:25288485. |
this study suggests that serotonin signaling through postsynaptic 5-ht1a receptors in the hippocampus is critical for the antidepressant-like effects of a cholinergic drug and begins to elucidate the molecular mechanisms underlying interactions between the serotonergic and cholinergic systems related to mood disorders. |
2016-01-05 |
2023-08-13 |
mouse |
| Ling-Na Han, Li Zhang, Li-Bo Li, Yi-Na Sun, Yong Wang, Li Chen, Yuan Guo, Yu-Ming Zhang, Qiao-Jun Zhang, Jian Li. Activation of serotonin(2C) receptors in the lateral habenular nucleus increases the expression of depression-related behaviors in the hemiparkinsonian rat. Neuropharmacology. vol 93. 2016-01-01. PMID:25661701. |
intra-lhb injection of ro60-0175 decreased dopamine, 5-ht and noradrenaline levels in the medial prefrontal cortex, habenula, hippocampus and amygdala in sham-operated and the lesioned rats. |
2016-01-01 |
2023-08-13 |
rat |
| Sarahi Lopez-Esparza, Laura C Berumen, Karla Padilla, Ricardo Miledi, Guadalupe García-Alcoce. Expression of hippocampal serotonin receptors 5-HT2C and 5-HT5A in a rat model of diet-induced obesity supplemented with tryptophan. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 42. 2015-12-30. PMID:25720309. |
expression of hippocampal serotonin receptors 5-ht2c and 5-ht5a in a rat model of diet-induced obesity supplemented with tryptophan. |
2015-12-30 |
2023-08-13 |
rat |
| Hai-Juan Li, Rui-Yun Peng, Chang-Zhen Wang, Si-Mo Qiao, Zou Yong, Ya-Bing Gao, Xin-Ping Xu, Shao-Xia Wang, Ji Dong, Hong-Yan Zuo, Zhao Li, Hong-Mei Zhou, Li-Feng Wang, Xiang-Jun H. Alterations of cognitive function and 5-HT system in rats after long term microwave exposure. Physiology & behavior. vol 140. 2015-12-28. PMID:25542888. |
we demonstrated that chronic exposure to microwave (2.856ghz, with the average power density of 5, 10, 20 and 30mw/cm(2)) could induce dose-dependent deficit of spatial learning and memory in rats accompanied with inhibition of brain electrical activity, the degeneration of hippocampus neurons, and the disturbance of neurotransmitters, among which the increase of 5-ht occurred as the main long-term change that the decrease of its metabolism partly contributed to. |
2015-12-28 |
2023-08-13 |
rat |
| Mónica Morais, Paulo A R Santos, António Mateus-Pinheiro, Patrícia Patrício, Luísa Pinto, Nuno Sousa, Pedro Pedroso, Susana Almeida, Augusto Filipe, João M Bess. The effects of chronic stress on hippocampal adult neurogenesis and dendritic plasticity are reversed by selective MAO-A inhibition. Journal of psychopharmacology (Oxford, England). vol 28. issue 12. 2015-12-23. PMID:25315831. |
in the present study, adult neurogenesis and neuronal morphology were examined in the hippocampus of rats exposed to chronic mild stress (cms) and treated with the selective reversible mao-a inhibitor (rima) drug, pirlindole and the selective serotonin reuptake inhibitor (ssri), fluoxetine. |
2015-12-23 |
2023-08-13 |
rat |
| Yifat Glikmann-Johnston, Michael M Saling, David C Reutens, Julie C Stou. Hippocampal 5-HT1A Receptor and Spatial Learning and Memory. Frontiers in pharmacology. vol 6. 2015-12-23. PMID:26696889. |
the hippocampus, which has a central role in spatial cognition, is characterized by high concentration of serotonin (5-hydroxytryptamine; 5-ht) receptor binding sites, particularly of the 1a receptor (5-ht1a) subtype. |
2015-12-23 |
2023-08-13 |
mouse |
| Wan-wan Liu, Lu Xu, Xian-zhe Dong, Xiao Tan, Shi Wang, Wei-yu Zhu, Ping Li. [Effects of Kaixin San formulas on behavioristics and central monoamine neurotransmitters of chronic stress rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 40. issue 11. 2015-12-17. PMID:26552177. |
the classic isolation method and the chronic unpredictable mild stress (cums) depression model were combined to investigate the changes in contents in hippocampus and monoamine neurotransmitters (ne, da, 5-ht) and the components of some formulas in plasma with hplc and uplc-q-tof-mse methods. |
2015-12-17 |
2023-08-13 |
rat |