| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhong-Min Wu, Li-Hua Yang, Rong Cui, Gui-Lian Ni, Feng-Tian Wu, Yong Lian. Contribution of Hippocampal 5-HT Cellular and molecular neurobiology. vol 37. issue 4. 2017-04-17. PMID:27324798. |
contribution of hippocampal 5-ht one of the hypotheses about the pathogenesis of posttraumatic stress disorder (ptsd) is the dysfunction of serotonin (5-ht) neurotransmission. |
2017-04-17 |
2023-08-13 |
Not clear |
| Katarzyna Jawna-Zboińska, Kamilla Blecharz-Klin, Ilona Joniec-Maciejak, Adriana Wawer, Justyna Pyrzanowska, Agnieszka Piechal, Dagmara Mirowska-Guzel, Ewa Widy-Tyszkiewic. Passiflora incarnata L. Improves Spatial Memory, Reduces Stress, and Affects Neurotransmission in Rats. Phytotherapy research : PTR. vol 30. issue 5. 2017-03-30. PMID:26814055. |
in addition, hippocampal glutamic acid and cortical serotonin content were depleted, with increased levels of metabolites and increased turnover. |
2017-03-30 |
2023-08-13 |
rat |
| M Vázquez-Gómez, D Valent, C García-Contreras, L Arroyo, C Óvilo, B Isabel, A Bassols, A González-Bulne. Sex and intrauterine growth restriction modify brain neurotransmitters profile of newborn piglets. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 55. 2017-03-28. PMID:27616302. |
the effects of iugr were modulated by sex; there were no significant differences between lbw and nbw females, but lbw males had higher hva concentration at the amygdala and higher concentration of 5-hydroxyindoleacetic acid, the serotonin metabolite, at the hippocampus than nbw males. |
2017-03-28 |
2023-08-13 |
Not clear |
| Jana D Tchekalarova, Natasha Ivanova, Dimitrina Atanasova, Daniela M Pechlivanova, Nikolai Lazarov, Lidia Kortenska, Rumiana Mitreva, Valentin Lozanov, Alexander Stoyne. Long-Term Treatment with Losartan Attenuates Seizure Activity and Neuronal Damage Without Affecting Behavioral Changes in a Model of Co-morbid Hypertension and Epilepsy. Cellular and molecular neurobiology. vol 36. issue 6. 2017-03-22. PMID:26464042. |
the levels of serotonin in the hippocampus and neuronal loss were estimated by hplc and hematoxylin and eosin staining, respectively. |
2017-03-22 |
2023-08-13 |
rat |
| Jana D Tchekalarova, Natasha Ivanova, Dimitrina Atanasova, Daniela M Pechlivanova, Nikolai Lazarov, Lidia Kortenska, Rumiana Mitreva, Valentin Lozanov, Alexander Stoyne. Long-Term Treatment with Losartan Attenuates Seizure Activity and Neuronal Damage Without Affecting Behavioral Changes in a Model of Co-morbid Hypertension and Epilepsy. Cellular and molecular neurobiology. vol 36. issue 6. 2017-03-22. PMID:26464042. |
however, the at1 receptor antagonist did not exert a substantial influence on concomitant with epilepsy behavioral changes and decreased 5-ht levels in the hippocampus. |
2017-03-22 |
2023-08-13 |
rat |
| Yasushi Yabuki, Kazuya Matsuo, Koga Hirano, Yasuharu Shinoda, Shigeki Moriguchi, Kohji Fukunag. Combined Memantine and Donepezil Treatment Improves Behavioral and Psychological Symptoms of Dementia-Like Behaviors in Olfactory Bulbectomized Mice. Pharmacology. vol 99. issue 3-4. 2017-03-17. PMID:28049192. |
to address mechanisms underlying these effects, we used in vivo microdialysis study and observed impaired nicotine-induced serotonin (5-ht) release in obx mouse hippocampus. |
2017-03-17 |
2023-08-13 |
mouse |
| Yasushi Yabuki, Kazuya Matsuo, Koga Hirano, Yasuharu Shinoda, Shigeki Moriguchi, Kohji Fukunag. Combined Memantine and Donepezil Treatment Improves Behavioral and Psychological Symptoms of Dementia-Like Behaviors in Olfactory Bulbectomized Mice. Pharmacology. vol 99. issue 3-4. 2017-03-17. PMID:28049192. |
combined memantine/donepezil administration, but not single administration of either, significantly antagonized the decrease in nicotine-induced 5-ht release seen in obx mouse hippocampus. |
2017-03-17 |
2023-08-13 |
mouse |
| Yasushi Yabuki, Kazuya Matsuo, Koga Hirano, Yasuharu Shinoda, Shigeki Moriguchi, Kohji Fukunag. Combined Memantine and Donepezil Treatment Improves Behavioral and Psychological Symptoms of Dementia-Like Behaviors in Olfactory Bulbectomized Mice. Pharmacology. vol 99. issue 3-4. 2017-03-17. PMID:28049192. |
these results suggest that improvement of bpsd-like behaviors by the co-administration of both drugs is in part mediated by enhanced 5-ht release and camkii activity in obx mouse hippocampus. |
2017-03-17 |
2023-08-13 |
mouse |
| Hidemi Yasuda, Akiko Harauma, Maki Kato, Yuki Ootomo, Erisa Hatanaka, Toru Moriguch. Artificially reared mice exhibit anxiety-like behavior in adulthood. Experimental animals. vol 65. issue 3. 2017-03-13. PMID:26948536. |
the hippocampal norepinephrine, serotonin, and 5-hydroxyindoleacetic acid levels in the artificially reared mice were significantly higher than those of the dam-reared mice. |
2017-03-13 |
2023-08-13 |
mouse |
| Saroj Kumar Das, Manorama Patr. Neuropeptide Y expression confers benzo[a]pyrene induced anxiolytic like behavioral response during early adolescence period of male Wistar rats. Neuropeptides. vol 61. 2017-03-09. PMID:27402563. |
the neurotransmitter estimation by hplc-ecd showed significant increase in 5-ht level in both hippocampus and hypothalamus of b[a]p treated group. |
2017-03-09 |
2023-08-13 |
rat |
| Yan-Fang Xian, Ding Fan, Siu-Po Ip, Qing-Qiu Mao, Zhi-Xiu Li. Antidepressant-Like Effect of Isorhynchophylline in Mice. Neurochemical research. vol 42. issue 2. 2017-03-07. PMID:27900600. |
in addition, irn treatment antagonized reserpine-induced ptosis and significantly enhanced the levels of monoamine neurotransmitters including norepinephrine (ne) and 5-hydroxytryptamine (5-ht), and the activity of monoamine oxidase a (mao-a) in the hippocampus and frontal cortex of mice. |
2017-03-07 |
2023-08-13 |
mouse |
| Xing-Hua Zhen, Ying-Chun Quan, Zhou Peng, Yan Han, Zhou-Jun Zheng, Li-Ping Gua. Design, Synthesis, and Potential Antidepressant-like Activity of 7-prenyloxy-2,3-dihydroflavanone Derivatives. Chemical biology & drug design. vol 87. issue 6. 2017-03-01. PMID:26705885. |
in addition, it was found that compounds 5j and 5k significantly increased the concentrations of the main neurotransmitters 5-ht and ne in the hippocampus, hypothalamus, and cortex. |
2017-03-01 |
2023-08-13 |
mouse |
| Xing-Hua Zhen, Ying-Chun Quan, Zhou Peng, Yan Han, Zhou-Jun Zheng, Li-Ping Gua. Design, Synthesis, and Potential Antidepressant-like Activity of 7-prenyloxy-2,3-dihydroflavanone Derivatives. Chemical biology & drug design. vol 87. issue 6. 2017-03-01. PMID:26705885. |
compounds 5j and 5k also significantly increased the contents of 5-hiaa in the hippocampus and cortex, shut down 5-ht metabolism compared with mice treated with stress vehicle. |
2017-03-01 |
2023-08-13 |
mouse |
| K Guo, G Yin, X H Zi, H X Zhu, Q Pa. Effect of selective serotonin reuptake inhibitors on expression of 5-HT1AR and neurotransmitters in rats with vascular dementia. Genetics and molecular research : GMR. vol 15. issue 4. 2017-03-01. PMID:27966748. |
this was accompanied by reductions in da, 5-ht, and ne levels in hippocampal tissues, as well as reduced cortical 5-ht and decreased 5-ht1ar mrna expression (p < 0.05). |
2017-03-01 |
2023-08-13 |
rat |
| K Guo, G Yin, X H Zi, H X Zhu, Q Pa. Effect of selective serotonin reuptake inhibitors on expression of 5-HT1AR and neurotransmitters in rats with vascular dementia. Genetics and molecular research : GMR. vol 15. issue 4. 2017-03-01. PMID:27966748. |
escitalopram treatments reduced escape latency, elevated platform crossing times, improved ca1 neuronal damage, increased da and 5-ht levels in hippocampal and cortical neurons, as well as elevated expression of 5-ht1ar mrna (p < 0.05). |
2017-03-01 |
2023-08-13 |
rat |
| Magdalena Jastrzębska-Więsek, Agata Siwek, Anna Partyka, Lucyna Antkiewicz-Michaluk, Jerzy Michaluk, Irena Romańska, Marcin Kołaczkowski, Anna Wesołowsk. Study of a mechanism responsible for potential antidepressant activity of EMD 386088, a 5-HT6 partial agonist in rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 389. issue 8. 2017-02-21. PMID:27106213. |
the concentrations of monoamines (dopamine (da), noradrenaline (na), and serotonin (5-ht)) and the rate of their metabolism were measured ex vivo in the brain structures (hippocampus, nucleus accumbens, striatum) using high-performance liquid chromatography (hplc). |
2017-02-21 |
2023-08-13 |
rat |
| Y Chandrasekhar, E M Ramya, K Navya, G Phani Kumar, K R Anilakuma. Antidepressant like effects of hydrolysable tannins of Terminalia catappa leaf extract via modulation of hippocampal plasticity and regulation of monoamine neurotransmitters subjected to chronic mild stress (CMS). Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 86. 2017-02-08. PMID:28012396. |
moreover, tc administration significantly restored cms induced changes in concentrations of hippocampal neurotransmitters (5-ht, da and ne) as well as levels of acetyl cholinesterase, cortisol, monoamine oxidases (mao-a, mao-b), bdnf, creb, and p-creb. |
2017-02-08 |
2023-08-13 |
mouse |
| Peter Petschner, Gabriella Juhasz, Viola Tamasi, Csaba Adori, Laszlo Tothfalusi, Tomas Hökfelt, Gyorgy Bagd. Chronic venlafaxine treatment fails to alter the levels of galanin system transcripts in normal rats. Neuropeptides. vol 57. 2017-02-07. PMID:26891823. |
to answer this question we administered the selective serotonin and noradrenaline reuptake inhibitor (snri) venlafaxine (40mg/kg/day via osmotic minipumps) to normal rats and examined the levels of the transcripts for galanin and galr1-3 after a 3-week venlafaxine treatment in the dorsal raphe, hippocampus and frontal cortex. |
2017-02-07 |
2023-08-13 |
rat |
| A Ahnaou, W H I M Drinkenbur. Simultaneous Changes in Sleep, qEEG, Physiology, Behaviour and Neurochemistry in Rats Exposed to Repeated Social Defeat Stress. Neuropsychobiology. vol 73. issue 4. 2017-02-07. PMID:27287886. |
on day 5, prefrontal dopamine (da) and hippocampal serotonin (5-ht) as well as corticosterone were measured in submissive rats that had visual, acoustic, and olfactory (but no physical) contact with a dominant, resident conspecific rat. |
2017-02-07 |
2023-08-13 |
rat |
| A Ahnaou, W H I M Drinkenbur. Simultaneous Changes in Sleep, qEEG, Physiology, Behaviour and Neurochemistry in Rats Exposed to Repeated Social Defeat Stress. Neuropsychobiology. vol 73. issue 4. 2017-02-07. PMID:27287886. |
the increased levels of cortical da and hippocampal 5-ht during social threat may reflect a coping mechanism to promote alertness and psychological adaptation to provocative and threatening stimuli. |
2017-02-07 |
2023-08-13 |
rat |