| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ying Wang, Shu-Ming Gao, Ran Li, Min Zhang, Shan Gao, Chun-Quan Y. Antidepressant-like effects of the Radix Bupleuri and Radix Paeoniae Alba drug pair. Neuroscience letters. vol 633. 2017-07-27. PMID:27619541. |
finally, the concentrations of monoamine neurotransmitters and their metabolites, namely epinephrine (ne), 5-hydroxytryptamine (5-ht), and 5-hydroxyindoleacetic acid (5-hiaa) in the hippocampal and cortical tissues of mice were detected with hplc with electrochemical detector. |
2017-07-27 |
2023-08-13 |
mouse |
| Ying Wang, Shu-Ming Gao, Ran Li, Min Zhang, Shan Gao, Chun-Quan Y. Antidepressant-like effects of the Radix Bupleuri and Radix Paeoniae Alba drug pair. Neuroscience letters. vol 633. 2017-07-27. PMID:27619541. |
after the administration of reserpine, the concentrations of 5-ht and ne in the hippocampal and cortical tissues were decreased; however, pre-treatment with the radix bupleuri and radix paeoniae alba drug pair significantly elevated the concentrations of 5-ht and ne in the hippocampal and cortical tissues. |
2017-07-27 |
2023-08-13 |
mouse |
| Guang-Fen Zhang, Jing Wang, Jin-Feng Han, Jie Guo, Ze-Min Xie, Wei Pan, Jian-Jun Yang, Kang-Jian Su. Acute single dose of ketamine relieves mechanical allodynia and consequent depression-like behaviors in a rat model. Neuroscience letters. vol 631. 2017-07-26. PMID:27497920. |
the hippocampus was harvested to determine the levels of interleukin (il)-6, il-1β, indoleamine 2,3-dioxygenase (ido), kynurenine (kyn), 5-hydroxytryptamine (5-ht), and tryptophan (trp). |
2017-07-26 |
2023-08-13 |
rat |
| Colm M P O'Tuathaigh, Fabio Fumagalli, Lieve Desbonnet, Francesc Perez-Branguli, Gerard Moloney, Samim Loftus, Claire O'Leary, Emilie Petit, Rachel Cox, Orna Tighe, Gerard Clarke, Donna Lai, Richard P Harvey, John F Cryan, Kevin J Mitchell, Timothy G Dinan, Marco A Riva, John L Waddingto. Epistatic and Independent Effects on Schizophrenia-Related Phenotypes Following Co-disruption of the Risk Factors Neuregulin-1 × DISC1. Schizophrenia bulletin. vol 43. issue 1. 2017-07-24. PMID:27613806. |
single gene disc1 mutants demonstrated a disruption in social cognition and nest-building, altered brain 5-hydroxytryptamine levels and hippocampal erbb4 expression, and decreased cortical expression of the schizophrenia-associated microrna mir-29b. |
2017-07-24 |
2023-08-13 |
Not clear |
| Maurizio S Riga, Connie Sánchez, Pau Celada, Francesc Artiga. Involvement of 5-HT3 receptors in the action of vortioxetine in rat brain: Focus on glutamatergic and GABAergic neurotransmission. Neuropharmacology. vol 108. 2017-07-07. PMID:27106166. |
here we assessed vortioxetine effect on pyramidal neuron activity and extracellular 5-ht concentration using in vivo extracellular recordings of rat medial prefrontal cortex (mpfc) pyramidal neurons and microdialysis in mpfc and ventral hippocampus (vhpc). |
2017-07-07 |
2023-08-13 |
rat |
| Burak Yulug, Lütfü Hanoglu, Ahmet M Tavli, Nesrin H Yılmaz, Ertugrul Kılı. The Brain Protective Effect of rTMS (Repetitive Transcranial Magnetic Stimulation) in Depression: A Mini-Review in Animal Studies. Medicinal chemistry (Shariqah (United Arab Emirates)). vol 12. issue 6. 2017-07-04. PMID:26434798. |
we have shown that rtms may exert significant neuroprotective effect through acting on the oxidative injury, stress hormones, dopamine and serotonin levels, brain derived neurotrophic factor expression, neuroinflamation and hippocampal cell proliferation. |
2017-07-04 |
2023-08-13 |
human |
| Ling Na Han, Li Zhang, Yi Na Sun, Cheng Xue Du, Yu Ming Zhang, Tao Wang, Jin Zhang, Jian Li. Serotonin7 receptors in the lateral habenular nucleus regulate depressive-like behaviors in the hemiparkinsonian rats. Brain research. vol 1644. 2017-06-29. PMID:27178363. |
neurochemical results showed that intra-lhb injection of as19 (4μg/rat) decreased dopamine and 5-ht levels in the medial prefrontal cortex, habenula and hippocampus in sham-operated and the lesioned rats; whereas sb269970 (6μg/rat) increased dopamine and 5-ht levels in these structures. |
2017-06-29 |
2023-08-13 |
rat |
| Brenna Bray, Jamie L Scholl, Wenyu Tu, Michael J Watt, Kenneth J Renner, Gina L Forste. Amphetamine withdrawal differentially affects hippocampal and peripheral corticosterone levels in response to stress. Brain research. vol 1644. 2017-06-29. PMID:27208490. |
amphetamine withdrawal is associated with heightened anxiety-like behavior, which is directly driven by blunted stress-induced glucocorticoid receptor-dependent serotonin release in the ventral hippocampus. |
2017-06-29 |
2023-08-13 |
rat |
| Laura Arroyo, Ricard Carreras, Daniel Valent, Raquel Peña, Eva Mainau, Antonio Velarde, Josefa Sabrià, Anna Bassol. Effect of handling on neurotransmitter profile in pig brain according to fear related behaviour. Physiology & behavior. vol 167. 2017-06-27. PMID:27737780. |
the most crucial pathway involved in the reaction of pigs to a stressful handling was the serotonergic system, and changes were observed in the amygdala with a decrease in serotonin (5-ht) and total indoleamines, and in the hippocampus, where this pathway was activated. |
2017-06-27 |
2023-08-13 |
Not clear |
| Chun-Sing Lam, George Lim Tipoe, Johnny Kong-Ching Wong, Moussa B H Youdim, Man-Lung Fun. M30 Antagonizes Indoleamine 2,3-Dioxygenase Activation and Neurodegeneration Induced by Corticosterone in the Hippocampus. PloS one. vol 11. issue 11. 2017-06-23. PMID:27870896. |
cort-treated rats exhibited depressive-like behavior with significant elevated levels of mao activities, serotonin turnover, oxidative stress, neuroinflammation and apoptosis in the hippocampus with significant losses of synaptic proteins when compared to the control. |
2017-06-23 |
2023-08-13 |
rat |
| Gongliang Zhang, David Cinalli, Sarah J Cohen, Kristina D Knapp, Lisa M Rios, José Martínez-Hernández, Rafael Luján, Robert W Stackma. Examination of the hippocampal contribution to serotonin 5-HT2A receptor-mediated facilitation of object memory in C57BL/6J mice. Neuropharmacology. vol 109. 2017-06-19. PMID:27114257. |
examination of the hippocampal contribution to serotonin 5-ht2a receptor-mediated facilitation of object memory in c57bl/6j mice. |
2017-06-19 |
2023-08-13 |
mouse |
| Gongliang Zhang, David Cinalli, Sarah J Cohen, Kristina D Knapp, Lisa M Rios, José Martínez-Hernández, Rafael Luján, Robert W Stackma. Examination of the hippocampal contribution to serotonin 5-HT2A receptor-mediated facilitation of object memory in C57BL/6J mice. Neuropharmacology. vol 109. 2017-06-19. PMID:27114257. |
serotonin 5-ht2a receptors (5-ht2ar) are widely expressed throughout the hippocampus. |
2017-06-19 |
2023-08-13 |
mouse |
| Hyun-Ja Jeong, Shi-Young Yang, Hee-Yun Kim, Na-Rae Kim, Jae-Bum Jang, Hyung-Min Ki. Chelidonic acid evokes antidepressant-like effect through the up-regulation of BDNF in forced swimming test. Experimental biology and medicine (Maywood, N.J.). vol 241. issue 14. 2017-06-14. PMID:27037280. |
in addition, chelidonic acid significantly increased the levels of 5-hydroxytryptamine (serotonin), dopamine, and norepinephrine compared with those levels for the mice that were administered distilled water in the hippocampus. |
2017-06-14 |
2023-08-13 |
mouse |
| Xue-Run Chang, Li Wang, Jing Li, Dian-Shui W. Analysis of anti-depressant potential of curcumin against depression induced male albino wistar rats. Brain research. vol 1642. 2017-05-23. PMID:26972530. |
chronic administration of curcumin significantly reversed levels of 3, 4-dihydroxyphenylacetic acid, noradrenaline, serotonin and 5-hydroxyindoleacetic acid in the hippocampus region of male albino rats. |
2017-05-23 |
2023-08-13 |
rat |
| Jolien Van Schoors, Johan Viaene, Yannick Van Wanseele, Ilse Smolders, Bieke Dejaegher, Yvan Vander Heyden, Ann Van Eeckhau. An improved microbore UHPLC method with electrochemical detection for the simultaneous determination of low monoamine levels in in vivo brain microdialysis samples. Journal of pharmaceutical and biomedical analysis. vol 127. 2017-05-15. PMID:26809614. |
the sensitive uhplc-ecd assay (lloq of 100pm for na and 150pm for da and 5-ht) with an analysis time of 8min for standard solutions and 20min for in vivo microdialysis samples originating from rat hippocampus, prefrontal cortex and striatum, is validated applying accuracy profiles. |
2017-05-15 |
2023-08-13 |
rat |
| Hongli Du, Keqing Wang, Li Su, Hongxia Zhao, Songyan Gao, Qishan Lin, Xiaofang Ma, Baokang Zhu, Xin Dong, Ziyang Lo. Metabonomic identification of the effects of the Zhimu-Baihe saponins on a chronic unpredictable mild stress-induced rat model of depression. Journal of pharmaceutical and biomedical analysis. vol 128. 2017-05-15. PMID:27371920. |
high performance liquid chromatography with electrochemical detection (hplc-ecd) was applied to determine the levels of three monoamine neurotransmitters, 5-hydroxytryptamine (5-ht), noradrenaline (ne) and dopamine (da), in the rat hippocampus. |
2017-05-15 |
2023-08-13 |
rat |
| Ju-Ryun Na, Dool-Ri Oh, SeulHee Han, Yu-Jin Kim, EunJin Choi, Donghyuck Bae, Dong Hwan Oh, Yoo-Hyun Lee, Sunoh Kim, Woojin Ju. Antistress Effects of Rosa rugosa Thunb. on Total Sleep Deprivation-Induced Anxiety-Like Behavior and Cognitive Dysfunction in Rat: Possible Mechanism of Action of 5-HT6 Receptor Antagonist. Journal of medicinal food. vol 19. issue 9. 2017-05-05. PMID:27331439. |
this study aimed to screen and identify the physiological antistress effects of an extract of r. rugosa (ro) on sleep deprivation-induced anxiety-like behavior and cognitive tests (in vivo) and tested for hippocampal cort and monoamine levels (ex vivo), corticosterone (cort)-induced injury, n-methyl-d-aspartate (nmda) receptor, and serotonin 6 (5-hydroxytryptamine 6, 5-ht6) receptor activities (in vitro) in search of active principles and underlying mechanisms of action. |
2017-05-05 |
2023-08-13 |
rat |
| Bhagyashree D Rao, Sandeep Shrivastava, Amitabha Chattopadhya. Effect of local anesthetics on serotonin Chemistry and physics of lipids. vol 201. 2017-05-02. PMID:27825964. |
in this work, we have explored the effect of petoh on the function of the hippocampal serotonin |
2017-05-02 |
2023-08-13 |
Not clear |
| Martin J Brodie, Frank Besag, Alan B Ettinger, Marco Mula, Gabriella Gobbi, Stefano Comai, Albert P Aldenkamp, Bernhard J Steinhof. Epilepsy, Antiepileptic Drugs, and Aggression: An Evidence-Based Review. Pharmacological reviews. vol 68. issue 3. 2017-04-20. PMID:27255267. |
we review the common neurotransmitter systems and brain regions implicated in both epilepsy and aggression, including the gaba, glutamate, serotonin, dopamine, and noradrenaline systems and the hippocampus, amygdala, prefrontal cortex, anterior cingulate cortex, and temporal lobes. |
2017-04-20 |
2023-08-13 |
Not clear |
| Mohit Kwatra, Ashok Jangra, Murli Mishra, Yogita Sharma, Sahabuddin Ahmed, Pinaki Ghosh, Vikas Kumar, Divya Vohora, Razia Khana. Naringin and Sertraline Ameliorate Doxorubicin-Induced Behavioral Deficits Through Modulation of Serotonin Level and Mitochondrial Complexes Protection Pathway in Rat Hippocampus. Neurochemical research. vol 41. issue 9. 2017-04-17. PMID:27209303. |
naringin and sertraline ameliorate doxorubicin-induced behavioral deficits through modulation of serotonin level and mitochondrial complexes protection pathway in rat hippocampus. |
2017-04-17 |
2023-08-13 |
rat |