| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tomoyuki Tashiro, Yuki Murakami, Akihiro Mouri, Yukio Imamura, Toshitaka Nabeshima, Yasuko Yamamoto, Kuniaki Sait. Kynurenine 3-monooxygenase is implicated in antidepressants-responsive depressive-like behaviors and monoaminergic dysfunctions. Behavioural brain research. vol 317. 2017-11-29. PMID:27693848. |
higher contents of trp metabolites such as kynurenine (kyn), kynurenic acid (ka), anthranilic acid (aa), and 3-hydroxykynurenine (3-hk) in the serum and hippocampus and decreased serotonin turnover and higher content of normetanephrine (nm) in the hippocampus were observed in the kmo ko mice. |
2017-11-29 |
2023-08-13 |
mouse |
| Celia Kjaerby, Jegath Athilingam, Sarah E Robinson, Jillian Iafrati, Vikaas S Soha. Serotonin 1B Receptors Regulate Prefrontal Function by Gating Callosal and Hippocampal Inputs. Cell reports. vol 17. issue 11. 2017-11-28. PMID:27974203. |
serotonin 1b receptors regulate prefrontal function by gating callosal and hippocampal inputs. |
2017-11-28 |
2023-08-13 |
mouse |
| Celia Kjaerby, Jegath Athilingam, Sarah E Robinson, Jillian Iafrati, Vikaas S Soha. Serotonin 1B Receptors Regulate Prefrontal Function by Gating Callosal and Hippocampal Inputs. Cell reports. vol 17. issue 11. 2017-11-28. PMID:27974203. |
here, we use a combination of optogenetics and synaptic physiology to show that serotonin acts presynaptically via 5-ht1b receptors to selectively suppress inputs from the contralateral mpfc and ventral hippocampus (vhpc), while sparing those from mediodorsal thalamus. |
2017-11-28 |
2023-08-13 |
mouse |
| Parijat Sarkar, Amitabha Chattopadhya. Solubilization of the serotonin Chemistry and physics of lipids. vol 209. 2017-11-28. PMID:28987925. |
in this work, we monitored solubilization of the bovine hippocampal serotonin |
2017-11-28 |
2023-08-13 |
cattle |
| Ning-Ning Song, Qiong Zhang, Ying Huang, Ling Chen, Yu-Qiang Ding, Lei Zhan. Enhanced dendritic morphogenesis of adult hippocampal newborn neurons in central 5-HT-deficient mice. Stem cell research. vol 19. 2017-11-22. PMID:28012347. |
serotonin (5-ht) plays an important role in regulating adult hippocampal neurogenesis. |
2017-11-22 |
2023-08-13 |
mouse |
| Ning-Ning Song, Qiong Zhang, Ying Huang, Ling Chen, Yu-Qiang Ding, Lei Zhan. Enhanced dendritic morphogenesis of adult hippocampal newborn neurons in central 5-HT-deficient mice. Stem cell research. vol 19. 2017-11-22. PMID:28012347. |
chronic administration of selective 5-ht reuptake inhibitors (ssris), which up-regulates extracellular 5-ht concentration, accelerates the maturation of adult-born hippocampal neurons. |
2017-11-22 |
2023-08-13 |
mouse |
| Ning-Ning Song, Qiong Zhang, Ying Huang, Ling Chen, Yu-Qiang Ding, Lei Zhan. Enhanced dendritic morphogenesis of adult hippocampal newborn neurons in central 5-HT-deficient mice. Stem cell research. vol 19. 2017-11-22. PMID:28012347. |
our findings indicate that reducing central 5-ht can accelerate the dendritic maturation of adult-born neurons, thus revealing a new role of central 5-ht in regulating adult hippocampal neurogenesis. |
2017-11-22 |
2023-08-13 |
mouse |
| Giuseppe Musumeci, Paola Castrogiovanni, Marta Anna Szychlinska, Rosa Imbesi, Carla Loreto, Sergio Castorina, Salvatore Giunt. Protective effects of high Tryptophan diet on aging-induced passive avoidance impairment and hippocampal apoptosis. Brain research bulletin. vol 128. 2017-11-21. PMID:27889579. |
in our previous work we have shown that l-tryptophan (trp) enriched diet prevents the age-induced decline of hippocampal serotonin (5-ht) production. |
2017-11-21 |
2023-08-13 |
rat |
| Giuseppe Musumeci, Paola Castrogiovanni, Marta Anna Szychlinska, Rosa Imbesi, Carla Loreto, Sergio Castorina, Salvatore Giunt. Protective effects of high Tryptophan diet on aging-induced passive avoidance impairment and hippocampal apoptosis. Brain research bulletin. vol 128. 2017-11-21. PMID:27889579. |
the increase in 5-ht neurotransmission in the hippocampus (hp) of aged rats was induced by 1 month of high trp administration. |
2017-11-21 |
2023-08-13 |
rat |
| Giuseppe Musumeci, Paola Castrogiovanni, Marta Anna Szychlinska, Rosa Imbesi, Carla Loreto, Sergio Castorina, Salvatore Giunt. Protective effects of high Tryptophan diet on aging-induced passive avoidance impairment and hippocampal apoptosis. Brain research bulletin. vol 128. 2017-11-21. PMID:27889579. |
altogether, our data suggest that enhanced trp intake, and in consequence a potential increase in 5-ht neurotransmission, might be beneficial in preventing age-related detrimental features by inhibition of hippocampal apoptosis. |
2017-11-21 |
2023-08-13 |
rat |
| Rubén García-Cabrerizo, M Julia García-Fuste. Comparative effects of amphetamine-like psychostimulants on rat hippocampal cell genesis at different developmental ages. Neurotoxicology. vol 56. 2017-11-20. PMID:27373168. |
moreover, the present results, in line with previous data, suggest a possible role for the neuroplasticity marker bdnf and serotonin in regulating cell survival, as mbdnf protein regulation paralleled hippocampal cell survival and 5-ht |
2017-11-20 |
2023-08-13 |
rat |
| Gehan S Georgy, Noha N Nassar, Hanaa A Mansour, Dalaal M Abdalla. Cerebrolysin Ameloriates Cognitive Deficits in Type III Diabetic Rats. PloS one. vol 8. issue 6. 2017-10-31. PMID:23840309. |
behavioral deficits were associated by decreased hippocampal glutamate (glu), glycine, serotonin (5-ht) and dopamine. |
2017-10-31 |
2023-08-12 |
rat |
| S M Brooker, K T Gobeske, J Chen, C-Y Peng, J A Kessle. Hippocampal bone morphogenetic protein signaling mediates behavioral effects of antidepressant treatment. Molecular psychiatry. vol 22. issue 6. 2017-10-17. PMID:27698430. |
treatment with the selective serotonin reuptake inhibitor fluoxetine suppressed bmp signaling in the adult mouse hippocampus both by decreasing levels of bmp4 ligand and increasing production of the bmp inhibitor noggin. |
2017-10-17 |
2023-08-13 |
mouse |
| Elsa Pittaras, Jacques Callebert, Mounir Chennaoui, Arnaud Rabat, Sylvie Grano. Individual behavioral and neurochemical markers of unadapted decision-making processes in healthy inbred mice. Brain structure & function. vol 221. issue 9. 2017-10-13. PMID:26860089. |
by contrast, high levels of dopamine, serotonin and noradrenalin in the hippocampus predicted the emergence of more exploratory and risky behaviors. |
2017-10-13 |
2023-08-13 |
mouse |
| Sebastian Pablo Fernandez, Bruno Cauli, Carolina Cabezas, Aude Muzerelle, Jean-Christophe Poncer, Patricia Gaspa. Multiscale single-cell analysis reveals unique phenotypes of raphe 5-HT neurons projecting to the forebrain. Brain structure & function. vol 221. issue 8. 2017-10-10. PMID:26608830. |
we compared the electrophysiological and neurochemical properties of dorsal and median raphe 5-ht neurons projecting to the medial prefrontal cortex (mpfc), amygdala (bla) and dorsal hippocampus (dhp), combining retrograde tract tracing with brain slice electrophysiology and single-cell rt-pcr in pet1-egfp mice. |
2017-10-10 |
2023-08-13 |
mouse |
| Sarah A Jablonski, Devon L Graham, Charles V Vorhees, Michael T William. Effects of Neonatal Methamphetamine and Stress on Brain Monoamines and Corticosterone in Preweanling Rats. Neurotoxicity research. vol 31. issue 2. 2017-10-10. PMID:27817108. |
separate litters were assessed at p15 or p20 for organ weights (adrenals, spleen, thymus); corticosterone; and monoamine assessments (dopamine, serotonin, norepinephrine) and their metabolites within the neostriatum, hippocampus, and prefrontal cortex. |
2017-10-10 |
2023-08-13 |
rat |
| Tianheng Hou, Xiaobo Li, Chongsheng Pen. Borneol enhances the antidepressant effects of asiaticoside by promoting its distribution into the brain. Neuroscience letters. vol 646. 2017-10-10. PMID:28263826. |
hippocampal 5-ht, ne, bdnf, and tnf-α levels were detected, and pathological changes were observed by h&e staining. |
2017-10-10 |
2023-08-13 |
rat |
| Cecilia Csölle, Mária Baranyi, Gabriella Zsilla, Agnes Kittel, Flóra Gölöncsér, Peter Illes, Edit Papp, E Sylvester Vizi, Beáta Sperlág. Neurochemical Changes in the Mouse Hippocampus Underlying the Antidepressant Effect of Genetic Deletion of P2X7 Receptors. PloS one. vol 8. issue 6. 2017-10-06. PMID:23805233. |
basal level of 5-ht was increased, whereas the 5hiaa/5-ht ratio was lower in the hippocampus of p2rx7-/- mice, which accompanied the increased uptake of [(3)h]5-ht and an elevated number of [(3)h]citalopram binding sites. |
2017-10-06 |
2023-08-12 |
mouse |
| Cecilia Csölle, Mária Baranyi, Gabriella Zsilla, Agnes Kittel, Flóra Gölöncsér, Peter Illes, Edit Papp, E Sylvester Vizi, Beáta Sperlág. Neurochemical Changes in the Mouse Hippocampus Underlying the Antidepressant Effect of Genetic Deletion of P2X7 Receptors. PloS one. vol 8. issue 6. 2017-10-06. PMID:23805233. |
in conclusion there are several potential mechanisms for the antidepressant phenotype of p2rx7-/- mice, such as the absence of p2rx7-mediated glutamate release, elevated basal bdnf production, enhanced neurogenesis and increased 5-ht bioavailability in the hippocampus. |
2017-10-06 |
2023-08-12 |
mouse |
| Leandro Cattelan Souza, Cristiano R Jesse, Marcelo Gomes de Gomes, Cristini Escobar Viana, Etiara Mattos, Neici Cáceres Silva, Silvana Peterini Boeir. Intracerebroventricular Administration of Streptozotocin as an Experimental Approach to Depression: Evidence for the Involvement of Proinflammatory Cytokines and Indoleamine-2,3-Dioxygenase. Neurotoxicity research. vol 31. issue 4. 2017-10-02. PMID:28155213. |
minocycline abrogates the increase in tryptophan and kynurenine levels as well as prevents serotonin dysfunction in the hippocampus of stz-injected mice. |
2017-10-02 |
2023-08-13 |
mouse |