| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Consolo, H Ladinsky, G L Forloni, P Gromb. Modulation of the hippocampal alpha-adrenoceptor population by lesion of the serotonergic raphe-hippocampal pathway in rats. Life sciences. vol 30. issue 13. 1982-07-08. PMID:6281602. |
electrolytic lesion of the ascending serotonergic fibers in the median raphe nucleus or in both the median raphe nucleus and dorsal raphe nucleus caused after 18 days more than 80% depletion of serotonin in the hippocampus and frontal cortex, respectively, without affecting norepinephrine and acetylcholine contents. |
1982-07-08 |
2023-08-12 |
rat |
| S Consolo, H Ladinsky, G L Forloni, P Gromb. Modulation of the hippocampal alpha-adrenoceptor population by lesion of the serotonergic raphe-hippocampal pathway in rats. Life sciences. vol 30. issue 13. 1982-07-08. PMID:6281602. |
the area-selective increase in alpha 1-adrenoceptor number in the hippocampus in the presence of unchanged norepinephrine content and in the absence of serotonin probably signifies that serotonin actively participates in the modulation of the noradrenergic receptor population. |
1982-07-08 |
2023-08-12 |
rat |
| M E Benwell, D J Balfou. Effects of chronic nicotine administration on the response and adaptation to stress. Psychopharmacology. vol 76. issue 2. 1982-07-08. PMID:6805027. |
repeated exposure to the stressful procedure resulted in complete adaptation of the adrenocortical response and the development of a significant (p less than 0.01) positive correlation between the plasma corticosterone and hippocampal 5-ht concentrations. |
1982-07-08 |
2023-08-12 |
rat |
| M E Benwell, D J Balfou. Effects of chronic nicotine administration on the response and adaptation to stress. Psychopharmacology. vol 76. issue 2. 1982-07-08. PMID:6805027. |
in nicotine-treated rats, complete adaptation did not occur and the plasma corticosterone showed a significant (p less than 0.05) negative correlation with hippocampal 5-ht. |
1982-07-08 |
2023-08-12 |
rat |
| M E Benwell, D J Balfou. Effects of chronic nicotine administration on the response and adaptation to stress. Psychopharmacology. vol 76. issue 2. 1982-07-08. PMID:6805027. |
nicotine withdrawal was not associated with any reduction in plasma corticosterone, but did abolish its relationship with hippocampal 5-ht. |
1982-07-08 |
2023-08-12 |
rat |
| G A Kennett, M H Josep. Does in vivo voltammetry in the hippocampus measure 5-HT release? Brain research. vol 236. issue 2. 1982-06-24. PMID:6461387. |
does in vivo voltammetry in the hippocampus measure 5-ht release? |
1982-06-24 |
2023-08-12 |
rat |
| G A Kennett, M H Josep. Does in vivo voltammetry in the hippocampus measure 5-HT release? Brain research. vol 236. issue 2. 1982-06-24. PMID:6461387. |
this study concerned the validation of the measurement of 5-ht release using scanning voltammetry at chronically implanted carbon paste/epoxy resin glass microelectrodes in the rat hippocampus. |
1982-06-24 |
2023-08-12 |
rat |
| G A Kennett, M H Josep. Does in vivo voltammetry in the hippocampus measure 5-HT release? Brain research. vol 236. issue 2. 1982-06-24. PMID:6461387. |
these results, together with the greater increase in signal following probenecid than tryptophan and the delayed increase after tryptophan, and interpreted as implying that extraneuronal 5hiaa and 5-ht contribute approximately equally to the hippocampal signal. |
1982-06-24 |
2023-08-12 |
rat |
| S Auerbach, P Lipto. Vasopressin augments depolarization-induced release and synthesis of serotonin in hippocampal slices. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 2. issue 4. 1982-06-24. PMID:7069467. |
vasopressin augments depolarization-induced release and synthesis of serotonin in hippocampal slices. |
1982-06-24 |
2023-08-12 |
rat |
| S Auerbach, P Lipto. Vasopressin augments depolarization-induced release and synthesis of serotonin in hippocampal slices. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 2. issue 4. 1982-06-24. PMID:7069467. |
the rat hippocampal slice contains serotonergic nerve terminals but not cell bodies; we studied the effect of vasopressin on the synthesis and release of serotonin from these nerve terminals during depolarization. |
1982-06-24 |
2023-08-12 |
rat |
| S Auerbach, P Lipto. Vasopressin augments depolarization-induced release and synthesis of serotonin in hippocampal slices. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 2. issue 4. 1982-06-24. PMID:7069467. |
the data show that vasopressin acts on a specific group of hippocampal nerve endings to increase serotonin synthesis. |
1982-06-24 |
2023-08-12 |
rat |
| T Kameyama, T Nabeshima, K Yamaguchi, K Kamata, M Ukai, S Okuyama, S Sakakibar. [Pharmacological action of eptazocine (l-1,4-dimethyl-10-hydroxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-banzazonine). (II) Relationship between the analgesic action of eptazocine and brain 5-hydroxytryptamine (5-HT) (author's transl)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 78. issue 6. 1982-05-27. PMID:6174403. |
in addition, eptazocine decreased the 5-hiaa level in the cortex and the 5-ht level in the hippocampus, but increased the 5-ht level in the spinal cord. |
1982-05-27 |
2023-08-12 |
Not clear |
| C M Forchetti, E J Marco, J L Mee. Serotonin and gamma-aminobutyric acid turnover after injection into the median raphe of substance P and D-ala-met-enkephalin amide. Journal of neurochemistry. vol 38. issue 5. 1982-05-27. PMID:6174697. |
serotonin turnover was increased by 30% in the hippocampus after the injection of substance p (4 micrograms) into the median raphe, indicating an excitatory effect of substance p on the raphe-hippocampal system. |
1982-05-27 |
2023-08-12 |
Not clear |
| C M Forchetti, E J Marco, J L Mee. Serotonin and gamma-aminobutyric acid turnover after injection into the median raphe of substance P and D-ala-met-enkephalin amide. Journal of neurochemistry. vol 38. issue 5. 1982-05-27. PMID:6174697. |
the injection fo gabaculine (80 ng) into the raphe increased gaba content by five times the control values, but hippocampal 5-ht and 5-hiaa contents were not significantly changed. |
1982-05-27 |
2023-08-12 |
Not clear |
| F J Vocci, G G Buterbaug. Hippocampal seizure discharge produced by systemic digitoxigenin is antagonized by reserpine or p-chlorophenylalanine. Neuropharmacology. vol 21. issue 1. 1982-05-27. PMID:6460943. |
the results suggest a role for monoamines, and in particular serotonin, in the effect of digitoxigenin to cause hippocampal seizure discharge. |
1982-05-27 |
2023-08-12 |
rat |
| R Hassler, P Haug, C Nitsch, J S Kim, K Pai. Effect of motor and premotor cortex ablation on concentrations of amino acids, monoamines, and acetylcholine and on the ultrastructure in rat striatum. A confirmation of glutamate as the specific cortico-striatal transmitter. Journal of neurochemistry. vol 38. issue 4. 1982-05-21. PMID:6121000. |
there was no decrease in other putative transmitters (dopamine, serotonin, acetylcholine, glycine and taurine), nor was a glutamate decrease observed in the hippocampus or in the hypothalamus, which do not receive direct premotor and motor cortical inputs. |
1982-05-21 |
2023-08-12 |
rat |
| L L Martin, R L Bouchal, D J Smit. Ketamine inhibits serotonin uptake in vivo. Neuropharmacology. vol 21. issue 2. 1982-05-21. PMID:6460944. |
furthermore, ketamine hcl (160 mg/kg) completely blocked the depletion of 5-ht by pca in every individual brain region studied (midbrain-thalamus, hypothalamus, striatum, hippocampus and cortex). |
1982-05-21 |
2023-08-12 |
Not clear |
| A Wiberg, R Adolfsson, B Eckert, B Winbla. The activity of monoamine oxidases A and B in gamma-irradiated rabbit brains. Experientia. vol 38. issue 1. 1982-04-22. PMID:7056361. |
the activities of monoamine oxidases a and b towards 5-hydroxytryptamine and beta-phenethylamine, respectively, were compared in the left and right caudatus, hippocampus, parietal cortex, cerebellum and frontal cortex 6 months after gamma-irradiation (single dose of 23 gy) of either the right hemisphere or of the whole rabbit brain (in which case, a dose of l6 gy). |
1982-04-22 |
2023-08-12 |
rabbit |
| J M Murphy, W J McBride, L Lumeng, T K L. Regional brain levels of monoamines in alcohol-preferring and -nonpreferring lines of rats. Pharmacology, biochemistry, and behavior. vol 16. issue 1. 1982-04-12. PMID:6173885. |
however, the predominant finding was that the levels of 5-ht and 5-hiaa were 12-26% lower for the p than for the np rats in the cx, hippocampus (hip), corpus striatum (str), thalamus (th) and hypothalamus (hy). |
1982-04-12 |
2023-08-12 |
rat |
| E C Azmitia, M J Perlow, M J Brennan, J M Laude. Fetal raphe and hippocampal transplants into adult and aged C57BL/6N mice: a preliminary immunocytochemical study. Brain research bulletin. vol 7. issue 6. 1982-04-12. PMID:7034870. |
conversely, adult 5-ht neurons send sprouts into fetal hippocampal tissue transplanted into the lateral ventricle. |
1982-04-12 |
2023-08-12 |
mouse |