| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C R Hung, J S Hong, S C Bond. Lack of asymmetrical distribution of receptor binding sites and of neurally active peptides within rat brain. Neuroscience. vol 7. issue 9. 1983-01-19. PMID:6183614. |
the high affinity binding of 5 tritiated (naloxone, spiroperidol, serotonin, quinuclidinylbenzilate, dihydroalprenolol) ligands to left and right frontal cortex, hippocampus and striatum has been compared in 8-week-old male rats. |
1983-01-19 |
2023-08-12 |
rat |
| A Fulton, T R Norman, H Cheng, G D Burrow. Assessment of the antidepressant activity of dothiepin and its metabolites by preclinical tests. Journal of affective disorders. vol 4. issue 3. 1982-12-21. PMID:6215444. |
using frontal cortical tissue suspensions and [3h]spiperone, the ic50 values were determined to be: dothiepin 4.2 x 10(-6) m, northiaden 5.0 x 10(-6) m, northiaden sulphoxide 1.6 x 10(-4) m and dothiepin sulphoxide 1.6 x 10(-4) m; whereas in hippocampal suspensions and using [3h]serotonin, the ic50 values were 2.5 x 10(-6) m, northiaden 4.0 x 10(-5) m, dothiepin sulphoxide 2.5 x 10(-4) m and northiaden sulphoxide greater than 10(-3) m. the influence of the drugs on the uptake of [14c]serotonin into human platelets was also investigated. |
1982-12-21 |
2023-08-12 |
human |
| D H Versteeg, E R De Kloet, G Szabó, G L Kovác. The effects of des-enkephalin-gamma-endorphin and des-Tyr1-a-endorphin on regional serotonin metabolism in rat brain. Brain research. vol 245. issue 2. 1982-12-21. PMID:7127078. |
des-enkephalin-gamma-endorphin (beta-endorphin6-17; de gamma e) causes a significant reduction of the serotonin concentration of the raphe area of the mesencephalon and of the dorsal hippocampus of the rat. |
1982-12-21 |
2023-08-12 |
rat |
| M Vergnes, E Kemp. Effect of hypothalamic injections of 5,7-dihydroxytryptamine on elicitation of mouse-killing in rats. Behavioural brain research. vol 5. issue 4. 1982-12-18. PMID:6889881. |
an overall and marked serotonin (5-ht) depletion of the brain was found to facilitate initiation of mouse-killing behavior in the rat, whereas more selective 5-ht depletions within forebrain structures such as the septum, hippocampus, cingular cortex and amygdala, did not have such an effect. |
1982-12-18 |
2023-08-12 |
rat |
| G Ellison, R Rata. The late stage following continuous amphetamine administration to rats is correlated with altered dopamine but not serotonin metabolism. Life sciences. vol 31. issue 8. 1982-12-16. PMID:7132578. |
the present results indicate that rats administered this same drug regimen have large decreases in dopamine (da), dihydroxyphenyl acetic acid (dopac), and homovanillic acid (hva) in caudate nucleus, smaller decreases in da with no changes in dopac and hva levels in nucleus accumbens, but no alterations in 5-hydroxytryptamine (5ht) and 5-hydroxyindole acetic acid (5hiaa) levels in caudate, accumbens, brainstem and hippocampus. |
1982-12-16 |
2023-08-12 |
rat |
| A Daszuta, M C Barri. Endogenous serotonin (5-HT) and 5-hydroxyindole acetic acid (5-HIAA) levels in large regions and in discrete brain areas of C57BL and BALBc mice at three times of the day. Brain research bulletin. vol 8. issue 5. 1982-12-02. PMID:6180811. |
endogenous 5-ht and 5-hiaa levels have also been measured in the different raphe nuclei and in the caudate nucleus and the hippocampus of these strains, using the micropunch technique and the radioenzymatic method (for 5-ht) and a new radioimmunoassay (for 5-hiaa). |
1982-12-02 |
2023-08-12 |
mouse |
| A Daszuta, M C Barri. Endogenous serotonin (5-HT) and 5-hydroxyindole acetic acid (5-HIAA) levels in large regions and in discrete brain areas of C57BL and BALBc mice at three times of the day. Brain research bulletin. vol 8. issue 5. 1982-12-02. PMID:6180811. |
in the forebrain the differences are reversed, except in the caudate nucleus and the hippocampus where the levels of 5-ht are identical in the two strains. |
1982-12-02 |
2023-08-12 |
mouse |
| A L Frankhuyzen, A H Mulde. Pharmacological characterization of presynaptic alpha-adrenoceptors modulating [3H]noradrenaline and [3H]5-hydroxytryptamine release from slices of the hippocampus of the rat. European journal of pharmacology. vol 81. issue 1. 1982-12-02. PMID:6288401. |
pharmacological characterization of presynaptic alpha-adrenoceptors modulating [3h]noradrenaline and [3h]5-hydroxytryptamine release from slices of the hippocampus of the rat. |
1982-12-02 |
2023-08-12 |
rat |
| A L Frankhuyzen, A H Mulde. Pharmacological characterization of presynaptic alpha-adrenoceptors modulating [3H]noradrenaline and [3H]5-hydroxytryptamine release from slices of the hippocampus of the rat. European journal of pharmacology. vol 81. issue 1. 1982-12-02. PMID:6288401. |
the experiments served to characterize the receptors mediating the inhibitory effect of alpha-adrenergic drugs on k+ (20 mm)-induced [3h]noradrenaline (na) and [3h]5-hydroxytryptamine ([3h]5-ht) release from slices of the dorsal part of rat hippocampus. |
1982-12-02 |
2023-08-12 |
rat |
| M Sega. Postsynaptic action of 5-hydroxytryptamine in the hippocampal slice. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 30. issue 8. 1982-12-02. PMID:7119423. |
postsynaptic action of 5-hydroxytryptamine in the hippocampal slice. |
1982-12-02 |
2023-08-12 |
Not clear |
| N A Otmakho. [Effect of noradrenaline and serotonin on responses of field CA3 neurons of hippocampal slices evoked by electric stimulation of mossy fibers]. Neirofiziologiia = Neurophysiology. vol 14. issue 4. 1982-12-02. PMID:7121636. |
[effect of noradrenaline and serotonin on responses of field ca3 neurons of hippocampal slices evoked by electric stimulation of mossy fibers]. |
1982-12-02 |
2023-08-12 |
Not clear |
| N A Otmakho. [Effect of noradrenaline and serotonin on responses of field CA3 neurons of hippocampal slices evoked by electric stimulation of mossy fibers]. Neirofiziologiia = Neurophysiology. vol 14. issue 4. 1982-12-02. PMID:7121636. |
responses of the ca3 neurons to mossy fibre stimulation were investigated in incubated hippocampal slices in vitro under the influence of norepinephrine (ne) and 5-hydroxytryptamine (5ht). |
1982-12-02 |
2023-08-12 |
Not clear |
| S Yamawaki, T Segawa, K Sara. Effects of acute and chronic toluene inhalation on behavior and (3H)-serotonin binding in rat. Life sciences. vol 30. issue 23. 1982-10-29. PMID:7109833. |
an examination of specific serotonin (3h-5ht) binding to crude synaptic membranes prepared from brains of rats subjected to acute and chronic toluene exposure revealed that while no changes in either apparent kd or apparent bmax occurred in acutely exposed animals, in chronically treated animals specific (3h)-5ht binding decreased in hippocampus and pons + medulla oblongata. |
1982-10-29 |
2023-08-12 |
rat |
| M Kurachi, D H Versteeg, J M Van Ree, H G Westernberg, H M Van Praa. Effect of des-Tyr1-gamma-endorphin on serotonin metabolism in rat brain regions. Experientia. vol 38. issue 5. 1982-09-24. PMID:6178616. |
administration of des-tyr1-gamma-endorphin (0.1 and 1.0 microgram) caused a decrease of the serotonin (5-ht) concentration of the hippocampus. |
1982-09-24 |
2023-08-12 |
rat |
| E R De Kloet, G L Kovács, G Szabó, G Telegdy, B Bohus, D H Verstee. Decreased serotonin turnover in the dorsal hippocampus of rat brain shortly after adrenalectomy: selective normalization after corticosterone substitution. Brain research. vol 239. issue 2. 1982-09-10. PMID:7093709. |
decreased serotonin turnover in the dorsal hippocampus of rat brain shortly after adrenalectomy: selective normalization after corticosterone substitution. |
1982-09-10 |
2023-08-12 |
rat |
| E R De Kloet, G L Kovács, G Szabó, G Telegdy, B Bohus, D H Verstee. Decreased serotonin turnover in the dorsal hippocampus of rat brain shortly after adrenalectomy: selective normalization after corticosterone substitution. Brain research. vol 239. issue 2. 1982-09-10. PMID:7093709. |
pargyline-induced accumulation of serotonin (5-ht) was used as an index of 5-ht turnover rate in the dorsal hippocampus. |
1982-09-10 |
2023-08-12 |
rat |
| E R De Kloet, G L Kovács, G Szabó, G Telegdy, B Bohus, D H Verstee. Decreased serotonin turnover in the dorsal hippocampus of rat brain shortly after adrenalectomy: selective normalization after corticosterone substitution. Brain research. vol 239. issue 2. 1982-09-10. PMID:7093709. |
the specificity of the 5-ht response in the hippocampus corresponds to the properties of the glucocorticoid receptor system in rat hippocampal neurons. |
1982-09-10 |
2023-08-12 |
rat |
| H Binde. [On the neuro-psychiatric symptomatology of the so-called "hepatic coma" (author's transl)]. Wiener klinische Wochenschrift. Supplementum. vol 134. 1982-07-19. PMID:7043904. |
the serotonin and 5-hydroxyindolaminoacid level in the tegmentum and the hippocampus are increased. |
1982-07-19 |
2023-08-12 |
Not clear |
| M A Geyer, C E Flicker, E H Le. Effects of tactile startle on serotonin content of midbrain raphe neurons in rats. Behavioural brain research. vol 4. issue 4. 1982-07-19. PMID:7073886. |
rats selected to exhibit comparable levels of behavioral reactivity to tactile startle stimuli were used to examine the effects of the startle testing itself on the levels of serotonin (5-ht) in the dorsal and median raphe nuclei and in the hippocampus. |
1982-07-19 |
2023-08-12 |
rat |
| M A Geyer, C E Flicker, E H Le. Effects of tactile startle on serotonin content of midbrain raphe neurons in rats. Behavioural brain research. vol 4. issue 4. 1982-07-19. PMID:7073886. |
a comparable decrease in 5-ht in the startled animals was found in the hippocampus, which receives its serotonergic innervation from the median raphe nucleus. |
1982-07-19 |
2023-08-12 |
rat |