| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R J Waldbillig, T J Bartness, B G Stanle. Increased food intake, body weight, and adiposity in rats after regional neurochemical depletion of serotonin. Journal of comparative and physiological psychology. vol 95. issue 3. 1981-09-22. PMID:7251949. |
however, substantial depletion of serotonin occurred in the septum, hippocampus, and hypothalamus of the 5,7-dht (12 microgram) group. |
1981-09-22 |
2023-08-12 |
rat |
| R L Commissaris, D J Mokler, W H Lyness, K E Moore, R H Rec. The behavioral effects of hallucinogens in rats following 5,7-dihydroxytryptamine administration into the medial forebrain bundle. Pharmacology, biochemistry, and behavior. vol 14. issue 6. 1981-09-15. PMID:6973157. |
male rats received 5,7-dht (6 micrograms/2 microliter) or vehicle injections bilaterally into the mfb; this procedure caused a significant reduction of 5-ht in the cortex, hippocampus and hypothalamus of lesioned rats, but not in the striatum. |
1981-09-15 |
2023-08-12 |
rat |
| L L Hernández, D A Powel. Forebrain norepinephrine and serotonin concentrations and cardiac conditioning in normal rabbits and rabbits with septal lesions. Brain research bulletin. vol 6. issue 6. 1981-09-15. PMID:7248812. |
after completion of training, norepinephrine (ne) and serotonin (5-ht) concentrations were determined in the hippocampus and neocortex to determine if lesion-induced amine depletion was related to changes in hr conditioned response (cr). |
1981-09-15 |
2023-08-12 |
Not clear |
| F H Gage, J E Springe. Behavioral assessment of norepinephrine and serotonin function and interaction in the hippocampal formation. Pharmacology, biochemistry, and behavior. vol 14. issue 6. 1981-09-15. PMID:7255517. |
ne injections were more effective in increasing reactivity when injected into the dorsal hippocampus while 5-ht injections were more effective in decreasing behavioral reactivity when injected into the ventral hippocampus. |
1981-09-15 |
2023-08-12 |
rat |
| F H Gage, J E Springe. Behavioral assessment of norepinephrine and serotonin function and interaction in the hippocampal formation. Pharmacology, biochemistry, and behavior. vol 14. issue 6. 1981-09-15. PMID:7255517. |
both ne and 5-ht were most effective in increasing open field behavior, however, when injected into the dorsal hippocampus. |
1981-09-15 |
2023-08-12 |
rat |
| F H Gage, J E Springe. Behavioral assessment of norepinephrine and serotonin function and interaction in the hippocampal formation. Pharmacology, biochemistry, and behavior. vol 14. issue 6. 1981-09-15. PMID:7255517. |
the results are discussed in terms of the functional significance of ne and 5-ht in the hippocampus, their modes of action and significance for understanding dorsal-ventral hippocampal differences. |
1981-09-15 |
2023-08-12 |
rat |
| M Hamon, D L Nelson, A Herbet, J Bockaert, J Glowinsk. Characteristics of serotonin receptors in the rat brain. Monographs in neural sciences. vol 7. 1981-07-23. PMID:7231436. |
performing chemical lesions on serotoninergic neurons by an intracerebral injection of 5, 7-dihydroxytryptamine or the blockade of central 5-ht receptors by the peripheral administration of methiothepin resulted in a subsequent increase in the number of specific binding sites for 3h-5-ht particularly in the hippocampus (+30 to +45%). |
1981-07-23 |
2023-08-12 |
rat |
| M Hamon, D L Nelson, A Herbet, J Bockaert, J Glowinsk. Characteristics of serotonin receptors in the rat brain. Monographs in neural sciences. vol 7. 1981-07-23. PMID:7231436. |
indeed, several observations strongly suggested that the high affinity binding site for 3h-5-ht did not correspond to the 5-ht receptor coupled to adenylate cyclase in synaptic membranes: 1) the apparent affinity of the 5-ht-sensitive adenylate cyclase for 5-ht was about 300 times lower (kd = 0.5 microm) than that of the specific 3h-5-ht binding site; 2)the ontogenic evolutions of 3h-5-ht binding and 5-ht-sensitive adenylate cyclase were not parallel, notably in the hippocampus; 3) they were differently affected by several drugs. |
1981-07-23 |
2023-08-12 |
rat |
| D Maślińska, I Lewandowska, J Prokopczy. Effect of prolonged acetylcholinesterase inhibition on postnatal brain development in rabbit. I. Level of serotonin in different brain regions. Acta neuropathologica. Supplementum. vol 7. 1981-06-25. PMID:6939284. |
after prolonged intoxication the decrease of serotonin concentration in brain stem, mesencephalon and hippocampus for 78, 74, 41% respectively was observed. |
1981-06-25 |
2023-08-12 |
rabbit |
| S O Ogren, S B Ross, H Hall, A C Holm, A L Reny. The pharmacology of zimelidine: a 5-HT selective reuptake inhibitor. Acta psychiatrica Scandinavica. Supplementum. vol 290. 1981-06-13. PMID:6452789. |
zim in vivo blocked the 5-ht uptake mechanism in the cerebral cortex, hippocampus, striatum, hypothalamus and spinal cord, thus indicating effects on both the ascending and descending 5-ht pathways. |
1981-06-13 |
2023-08-12 |
mouse |
| S Tanaka, A Tsujimot. Somatostatin facilitates the serotonin release from rat cerebral cortex, hippocampus and hypothalamus slices. Brain research. vol 208. issue 1. 1981-05-28. PMID:6110467. |
somatostatin facilitates the serotonin release from rat cerebral cortex, hippocampus and hypothalamus slices. |
1981-05-28 |
2023-08-12 |
rat |
| S Tanaka, A Tsujimot. Somatostatin facilitates the serotonin release from rat cerebral cortex, hippocampus and hypothalamus slices. Brain research. vol 208. issue 1. 1981-05-28. PMID:6110467. |
the effect of somatostatin on the release of serotonin (5-ht) from the superfused slices of rat cerebral cortex, hippocampus and hypothalamus preloaded with [3h]5-ht was examined. |
1981-05-28 |
2023-08-12 |
rat |
| J H Williams, E C Azmiti. Hippocampal serotonin re-uptake and nocturnal locomotor activity after microinjections of 5,7-DHT in the fornix-fimbria. Brain research. vol 207. issue 1. 1981-05-28. PMID:7470907. |
hippocampal serotonin re-uptake and nocturnal locomotor activity after microinjections of 5,7-dht in the fornix-fimbria. |
1981-05-28 |
2023-08-12 |
rat |
| J H Williams, E C Azmiti. Hippocampal serotonin re-uptake and nocturnal locomotor activity after microinjections of 5,7-DHT in the fornix-fimbria. Brain research. vol 207. issue 1. 1981-05-28. PMID:7470907. |
the role of the hippocampal 5-hydroxytryptamine (5-ht) terminals in the control of locomotor activity was investigated by lesioning 5-ht axons in the fimbria with 5,7-dihydroxytryptamine (5,7-dht). |
1981-05-28 |
2023-08-12 |
rat |
| J H Williams, E C Azmiti. Hippocampal serotonin re-uptake and nocturnal locomotor activity after microinjections of 5,7-DHT in the fornix-fimbria. Brain research. vol 207. issue 1. 1981-05-28. PMID:7470907. |
twenty-eight to thirty days after operation degeneration of 5-ht terminals was assessed by measuring in vitro [3h]5-ht re-uptake in slices of dorsal hippocampus, ventral hippocampus and the septum. |
1981-05-28 |
2023-08-12 |
rat |
| J H Williams, E C Azmiti. Hippocampal serotonin re-uptake and nocturnal locomotor activity after microinjections of 5,7-DHT in the fornix-fimbria. Brain research. vol 207. issue 1. 1981-05-28. PMID:7470907. |
a reduction of [3h]5-ht re-uptake was found in dorsal hippocampus which was related to the dose of 5,7-dht), but ventral hippocampal and septal [3h]5-ht re-uptake were not systematically reduced. |
1981-05-28 |
2023-08-12 |
rat |
| J H Williams, E C Azmiti. Hippocampal serotonin re-uptake and nocturnal locomotor activity after microinjections of 5,7-DHT in the fornix-fimbria. Brain research. vol 207. issue 1. 1981-05-28. PMID:7470907. |
for each rat, levels of dorsal and ventral hippocampal [3h]5-ht re-uptake were negatively correlated with the mean nocturnal activity from the 7 nights of testing. |
1981-05-28 |
2023-08-12 |
rat |
| J H Williams, E C Azmiti. Hippocampal serotonin re-uptake and nocturnal locomotor activity after microinjections of 5,7-DHT in the fornix-fimbria. Brain research. vol 207. issue 1. 1981-05-28. PMID:7470907. |
levels of dorsal, but not ventral hippocampal [3h]5-ht re-uptake were negatively correlated with the mean nightly decrement of activity. |
1981-05-28 |
2023-08-12 |
rat |
| J H Williams, E C Azmiti. Hippocampal serotonin re-uptake and nocturnal locomotor activity after microinjections of 5,7-DHT in the fornix-fimbria. Brain research. vol 207. issue 1. 1981-05-28. PMID:7470907. |
these results, indicate that the increase in nocturnal locomotor activity caused by generalized depletion of 5-ht in the brain may be due to disruption of hippocampal 5-ht terminals supplied by the fornix-fimbria. |
1981-05-28 |
2023-08-12 |
rat |
| J Francis, L L Hernández, D A Powel. Lateral hypothalamic lesions: effects on Pavlovian cardiac and eyeblink conditioning in the rabbit. Brain research bulletin. vol 6. issue 2. 1981-05-26. PMID:6970611. |
cortical and hippocampal 5-ht and ne concentrations were significantly depleted in lesioned as compared to control animals. |
1981-05-26 |
2023-08-12 |
rabbit |