| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Shenker, S Maayani, H Weinstein, J P Gree. Enhanced serotonin-stimulated adenylate cyclase activity in membranes from adult guinea pig hippocampus. Life sciences. vol 32. issue 20. 1983-06-23. PMID:6573550. |
we have developed an assay for serotonin (5-ht) stimulation of adenylate cyclase activity in membranes from adult guinea pig hippocampus. |
1983-06-23 |
2023-08-12 |
Not clear |
| M R Whipple, M G Reinecke, F H Gag. Inhibition of synaptosomal neurotransmitter uptake by hallucinogens. Journal of neurochemistry. vol 40. issue 4. 1983-05-05. PMID:6131933. |
the effect of 13 hallucinogens on the uptake of serotonin and norepinephrine into hippocampal synaptosomes and of serotonin and dopamine into caudate synaptosomes was found to be inhibitory, except for lysergic acid diethylamide and 2-bromolysergic acid diethylamide, which were inactive. |
1983-05-05 |
2023-08-12 |
Not clear |
| J R Martin, J Dedek, P Driscol. Portacaval anastomosis in rats: effects on behavior and brain serotonin metabolism. Pharmacology, biochemistry, and behavior. vol 18. issue 2. 1983-05-05. PMID:6188179. |
subsequently, serotonin and 5-hydroxyindoleacetic acid levels were measured for hypothalamus, striatum, hippocampus, and midbrain-medulla. |
1983-05-05 |
2023-08-12 |
rat |
| S E Robinso. Effect of specific serotonergic lesions on cholinergic neurons in the hippocampus, cortex and striatum. Life sciences. vol 32. issue 4. 1983-04-15. PMID:6827899. |
local injection of 5,7-dihydroxytryptamine into the median raphe nucleus of rats pretreated with desipramine decreases the serotonin content of the hippocampus and cortex. |
1983-04-15 |
2023-08-12 |
rat |
| S E Robinso. Effect of specific serotonergic lesions on cholinergic neurons in the hippocampus, cortex and striatum. Life sciences. vol 32. issue 4. 1983-04-15. PMID:6827899. |
local injection of 5,7-dihydroxytryptamine into the dorsal raphe nucleus of desipramine-treated rats decreases the serotonin content of the hippocampus, cortex, and striatum. |
1983-04-15 |
2023-08-12 |
rat |
| N A Otmakhov, A G Bragi. Effects of norepinephrine and serotonin upon spontaneous activity and responses to mossy fiber stimulation of CA3 neurons in hippocampal slices. Brain research. vol 253. issue 1-2. 1983-03-24. PMID:6295549. |
effects of norepinephrine and serotonin upon spontaneous activity and responses to mossy fiber stimulation of ca3 neurons in hippocampal slices. |
1983-03-24 |
2023-08-12 |
rat |
| N A Otmakhov, A G Bragi. Effects of norepinephrine and serotonin upon spontaneous activity and responses to mossy fiber stimulation of CA3 neurons in hippocampal slices. Brain research. vol 253. issue 1-2. 1983-03-24. PMID:6295549. |
effects of norepinephrine (ne) and 5-hydroxytryptamine (5-ht) upon spontaneous activity and responses to mossy fiber stimulation (mfs) were tested in 192 units of the field ca3 in the guinea pig and rat hippocampal slices. |
1983-03-24 |
2023-08-12 |
rat |
| A Yonezawa, T Tadano, S Urano, K Kisara, Y Kimur. [Effects of methyl o-(4-hydroxy-3-methoxycinnamoyl) reserpate (CD-3400) on erection and ejaculation in dogs]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 80. issue 3. 1983-03-11. PMID:6130031. |
24 hr after oral administration in a single dose of cd-3400 (0.5 mg/kg), reserpine (0.125 mg/kg) or rescinnamine (0.125 mg/kg), the ratios of dopamine (da) to serotonin (5-ht) in the anterior hypothalamus and hippocampus were decreased significantly as compared with the control. |
1983-03-11 |
2023-08-12 |
Not clear |
| A Yonezawa, T Tadano, S Urano, K Kisara, Y Kimur. [Effects of methyl o-(4-hydroxy-3-methoxycinnamoyl) reserpate (CD-3400) on erection and ejaculation in dogs]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 80. issue 3. 1983-03-11. PMID:6130031. |
these results indicate that cd-3400 results in a weaker suppressive effect on ejaculation as compared to reserpine and rescinnamine, and cd-3400-induced suppression may be due to a decrease in the ratio of da to 5-ht in the anterior hypothalamus and hippocampus. |
1983-03-11 |
2023-08-12 |
Not clear |
| J M Lauder, J A Wallace, H Krebs, P Petrusz, K McCarth. In vivo and in vitro development of serotonergic neurons. Brain research bulletin. vol 9. issue 1-6. 1983-02-25. PMID:6129049. |
postnatal studies using this immunocytochemical-autoradiographic method also provide evidence for interactions of 5-ht axons with proliferating glioblasts in the developing cerebellum and with immature granule cells and their precursors in the hippocampus. |
1983-02-25 |
2023-08-12 |
rat |
| O L Segal, V N Mat. [Effect of the development of local motor-food conditioned reflexes on the protein content in hippocampal neurons with surplus serotonin in the rat brain]. Nauchnye doklady vysshei shkoly. Biologicheskie nauki. issue 10. 1983-02-25. PMID:7171652. |
[effect of the development of local motor-food conditioned reflexes on the protein content in hippocampal neurons with surplus serotonin in the rat brain]. |
1983-02-25 |
2023-08-12 |
rat |
| M E Benwell, D J Balfou. The effects of nicotine administration on 5-HT uptake and biosynthesis in rat brain. European journal of pharmacology. vol 84. issue 1-2. 1983-01-27. PMID:7140821. |
both the acute and chronic (40 days) administration of nicotine (0.4 mg/kg s.c.) caused a decrease in the rate of formation of 5-ht by hippocampal synaptosomes (p less than 0.05) while 24 h withdrawal of the drug from chronically treated rats resulted in a partial recovery of this effect. |
1983-01-27 |
2023-08-12 |
rat |
| C R Hung, J S Hong, S C Bond. Lack of asymmetrical distribution of receptor binding sites and of neurally active peptides within rat brain. Neuroscience. vol 7. issue 9. 1983-01-19. PMID:6183614. |
the high affinity binding of 5 tritiated (naloxone, spiroperidol, serotonin, quinuclidinylbenzilate, dihydroalprenolol) ligands to left and right frontal cortex, hippocampus and striatum has been compared in 8-week-old male rats. |
1983-01-19 |
2023-08-12 |
rat |
| A Fulton, T R Norman, H Cheng, G D Burrow. Assessment of the antidepressant activity of dothiepin and its metabolites by preclinical tests. Journal of affective disorders. vol 4. issue 3. 1982-12-21. PMID:6215444. |
using frontal cortical tissue suspensions and [3h]spiperone, the ic50 values were determined to be: dothiepin 4.2 x 10(-6) m, northiaden 5.0 x 10(-6) m, northiaden sulphoxide 1.6 x 10(-4) m and dothiepin sulphoxide 1.6 x 10(-4) m; whereas in hippocampal suspensions and using [3h]serotonin, the ic50 values were 2.5 x 10(-6) m, northiaden 4.0 x 10(-5) m, dothiepin sulphoxide 2.5 x 10(-4) m and northiaden sulphoxide greater than 10(-3) m. the influence of the drugs on the uptake of [14c]serotonin into human platelets was also investigated. |
1982-12-21 |
2023-08-12 |
human |
| D H Versteeg, E R De Kloet, G Szabó, G L Kovác. The effects of des-enkephalin-gamma-endorphin and des-Tyr1-a-endorphin on regional serotonin metabolism in rat brain. Brain research. vol 245. issue 2. 1982-12-21. PMID:7127078. |
des-enkephalin-gamma-endorphin (beta-endorphin6-17; de gamma e) causes a significant reduction of the serotonin concentration of the raphe area of the mesencephalon and of the dorsal hippocampus of the rat. |
1982-12-21 |
2023-08-12 |
rat |
| M Vergnes, E Kemp. Effect of hypothalamic injections of 5,7-dihydroxytryptamine on elicitation of mouse-killing in rats. Behavioural brain research. vol 5. issue 4. 1982-12-18. PMID:6889881. |
an overall and marked serotonin (5-ht) depletion of the brain was found to facilitate initiation of mouse-killing behavior in the rat, whereas more selective 5-ht depletions within forebrain structures such as the septum, hippocampus, cingular cortex and amygdala, did not have such an effect. |
1982-12-18 |
2023-08-12 |
rat |
| G Ellison, R Rata. The late stage following continuous amphetamine administration to rats is correlated with altered dopamine but not serotonin metabolism. Life sciences. vol 31. issue 8. 1982-12-16. PMID:7132578. |
the present results indicate that rats administered this same drug regimen have large decreases in dopamine (da), dihydroxyphenyl acetic acid (dopac), and homovanillic acid (hva) in caudate nucleus, smaller decreases in da with no changes in dopac and hva levels in nucleus accumbens, but no alterations in 5-hydroxytryptamine (5ht) and 5-hydroxyindole acetic acid (5hiaa) levels in caudate, accumbens, brainstem and hippocampus. |
1982-12-16 |
2023-08-12 |
rat |
| A Daszuta, M C Barri. Endogenous serotonin (5-HT) and 5-hydroxyindole acetic acid (5-HIAA) levels in large regions and in discrete brain areas of C57BL and BALBc mice at three times of the day. Brain research bulletin. vol 8. issue 5. 1982-12-02. PMID:6180811. |
endogenous 5-ht and 5-hiaa levels have also been measured in the different raphe nuclei and in the caudate nucleus and the hippocampus of these strains, using the micropunch technique and the radioenzymatic method (for 5-ht) and a new radioimmunoassay (for 5-hiaa). |
1982-12-02 |
2023-08-12 |
mouse |
| A Daszuta, M C Barri. Endogenous serotonin (5-HT) and 5-hydroxyindole acetic acid (5-HIAA) levels in large regions and in discrete brain areas of C57BL and BALBc mice at three times of the day. Brain research bulletin. vol 8. issue 5. 1982-12-02. PMID:6180811. |
in the forebrain the differences are reversed, except in the caudate nucleus and the hippocampus where the levels of 5-ht are identical in the two strains. |
1982-12-02 |
2023-08-12 |
mouse |
| A L Frankhuyzen, A H Mulde. Pharmacological characterization of presynaptic alpha-adrenoceptors modulating [3H]noradrenaline and [3H]5-hydroxytryptamine release from slices of the hippocampus of the rat. European journal of pharmacology. vol 81. issue 1. 1982-12-02. PMID:6288401. |
pharmacological characterization of presynaptic alpha-adrenoceptors modulating [3h]noradrenaline and [3h]5-hydroxytryptamine release from slices of the hippocampus of the rat. |
1982-12-02 |
2023-08-12 |
rat |