| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yael Abreu-Villaça, Vinicius M S Guimarães, André Nunes-Freitas, Ana Carolina Dutra-Tavares, Alex C Manhães, Claudio C Filgueiras, Anderson Ribeiro-Carvalh. Tobacco smoke and ethanol during adolescence: Both combined- and single-drug exposures lead to short- and long-term disruption of the serotonergic system in the mouse brain. Brain research bulletin. vol 146. 2020-03-10. PMID:30584905. |
at pn45 (end-of-exposure), hippocampal serotonin transporter (5 h tt) binding was increased in smk and decreased in etoh male mice. |
2020-03-10 |
2023-08-13 |
mouse |
| Liubov S Kalinichenko, Lara Hammad, Martin Reichel, Zacharias Kohl, Erich Gulbins, Johannes Kornhuber, Christian P Mülle. Acid sphingomyelinase controls dopamine activity and responses to appetitive stimuli in mice. Brain research bulletin. vol 146. 2020-03-10. PMID:30716394. |
we found reduced basal extracellular da levels in the nucleus accumbens (nac) and dorsal hippocampus (dh) of tgasm mice with little effect on 5-ht and ne levels. |
2020-03-10 |
2023-08-13 |
mouse |
| Dai Han, Shenxun Shi, Hong Lu. The therapeutic effect of quetiapine on cognitive impairment associated with 5-HT1A presynaptic receptor involved schizophrenia. Journal of integrative neuroscience. vol 18. issue 3. 2020-03-05. PMID:31601072. |
we measured the levels of cognitive impairment using the morris water maze test and protein kinase a activity in hippocampal neurons on presynaptic and postsynaptic serotonin 1a receptors to investigate the effect of dizocilpine-induced cognitive impairment associated with atypical antipsychotic drugs in rats treated by quetiapine alone or combined with way100635/tandospirone. |
2020-03-05 |
2023-08-13 |
human |
| Zian Xia, Chunhu Zhang, Yuanhao Du, Wei Huang, Zhihua Xing, Hui Cao, Kechao Nie, Yang Wang, Xingui Xiong, Bo Yan. The Effect of Traditional Chinese Medicine Zhike-Houpu Herbal Pair on Depressive Behaviors and Hippocampal Serotonin 1A Receptors in Rats After Chronic Unpredictable Mild Stress. Psychosomatic medicine. vol 81. issue 1. 2020-03-02. PMID:30216226. |
the effect of traditional chinese medicine zhike-houpu herbal pair on depressive behaviors and hippocampal serotonin 1a receptors in rats after chronic unpredictable mild stress. |
2020-03-02 |
2023-08-13 |
rat |
| Ankit Uniyal, Raghunath Singh, Ansab Akhtar, Yashika Bansal, Anurag Kuhad, Sangeeta Pilkhwal Sa. Co-treatment of piracetam with risperidone rescued extinction deficits in experimental paradigms of post-traumatic stress disorder by restoring the physiological alterations in cortex and hippocampus. Pharmacology, biochemistry, and behavior. vol 185. 2020-02-26. PMID:31445955. |
neurotransmitters (dopamine and serotonin and their metabolites), bdnf, proinflammatory cytokines (tnf-α, il-6), caspase-3, and markers for oxidative stress were assessed in the hippocampus and cortex while corticosterone and nitrite levels were estimated in plasma. |
2020-02-26 |
2023-08-13 |
rat |
| Daehyuk Jang, Hyun-Ju Lee, Kyungjun Lee, Kyu-Ri Kim, Ran Won, Seung Eun Lee, Insop Shi. White Ginseng Ameliorates Depressive Behavior and Increases Hippocampal 5-HT Level in the Stressed Ovariectomized Rats. BioMed research international. vol 2019. 2020-02-26. PMID:31612144. |
white ginseng ameliorates depressive behavior and increases hippocampal 5-ht level in the stressed ovariectomized rats. |
2020-02-26 |
2023-08-13 |
rat |
| Sophia French, Carter Wra. Serotonin Syndrome and Hippocampal Infarction. Pediatric neurology. vol 90. 2020-02-25. PMID:30420109. |
serotonin syndrome and hippocampal infarction. |
2020-02-25 |
2023-08-13 |
Not clear |
| Shuo Wang, Yasushi Yabuki, Kazuya Matsuo, Jing Xu, Hisanao Izumi, Kenji Sakimura, Takashi Saito, Takaomi C Saido, Kohji Fukunag. Correction: T-type calcium channel enhancer SAK3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice. PloS one. vol 14. issue 1. 2020-02-25. PMID:30682166. |
correction: t-type calcium channel enhancer sak3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice. |
2020-02-25 |
2023-08-13 |
mouse |
| Yang Li, Jing Liu, Xu Liu, Cun-Jin Su, Qi-Lin Zhang, Zhi-Hong Wang, Lei-Fang Cao, Xue-Yan Guo, Ya Huang, Weifeng Luo, Tong Li. Antidepressant-Like Action of Single Facial Injection of Botulinum Neurotoxin A is Associated with Augmented 5-HT Levels and BDNF/ERK/CREB Pathways in Mouse Brain. Neuroscience bulletin. vol 35. issue 4. 2020-02-18. PMID:30900142. |
bont/a significantly increased the 5-hydroxytryptamine (5-ht) levels in several brain regions, including the hippocampus and hypothalamus, in srs mice. |
2020-02-18 |
2023-08-13 |
mouse |
| Yang Li, Jing Liu, Xu Liu, Cun-Jin Su, Qi-Lin Zhang, Zhi-Hong Wang, Lei-Fang Cao, Xue-Yan Guo, Ya Huang, Weifeng Luo, Tong Li. Antidepressant-Like Action of Single Facial Injection of Botulinum Neurotoxin A is Associated with Augmented 5-HT Levels and BDNF/ERK/CREB Pathways in Mouse Brain. Neuroscience bulletin. vol 35. issue 4. 2020-02-18. PMID:30900142. |
collectively, these results demonstrated that bont/a treatment has anti-depressant-like activity in mice, and this is associated with increased 5-ht levels and the activation of bdnf/erk/creb pathways in the hippocampus, supporting further investigation of bont/a therapy in depression. |
2020-02-18 |
2023-08-13 |
mouse |
| Atef Tadros Fahim, Amal Ahmed Abd El-Fattah, Nermin Abdel Hamid Sadik, Bassam Mohamed Al. Resveratrol and dimethyl fumarate ameliorate testicular dysfunction caused by chronic unpredictable mild stress-induced depression in rats. Archives of biochemistry and biophysics. vol 665. 2020-02-14. PMID:30904419. |
cums-induced depressive-like behaviours in rats were evidenced by increased serum corticosterone levels and decreased serum and hippocampal serotonin levels as well as decreased hippocampal bdnf levels. |
2020-02-14 |
2023-08-13 |
rat |
| Emily L Brooks, Vongai S Mutengwa, Aya Abdalla, Mark S Yeoman, Bhavik Anil Pate. Determination of tryptophan metabolism from biological tissues and fluids using high performance liquid chromatography with simultaneous dual electrochemical detection. The Analyst. vol 144. issue 20. 2020-02-14. PMID:31538156. |
responses from the hippocampus, blood and ileum mucosa highlighted that each region had a varying ratio of serotonin to kynurenine pathway, indicating varied approaches to tryptophan metabolism. |
2020-02-14 |
2023-08-13 |
Not clear |
| Xinnan Zhao, Fengrui Cao, Qing Liu, Xinsheng Li, Guoyang Xu, Gang Liu, Yanli Zhang, Xiaohan Yang, Shansong Yi, Fenghua Xu, Kai Fan, Jianmei M. Behavioral, inflammatory and neurochemical disturbances in LPS and UCMS-induced mouse models of depression. Behavioural brain research. vol 364. 2020-02-13. PMID:28572058. |
the decrease of 5-ht and bdnf was detected only in hippocampus of lps-stressed mice, but in overall all the brain areas assessed in ucms-stressed mice as compared to control. |
2020-02-13 |
2023-08-13 |
mouse |
| Sandra Tillmann, Denise F Happ, Per F Mikkelsen, Juergen Geisel, Gregers Wegener, Rima Obei. Behavioral and metabolic effects of S-adenosylmethionine and imipramine in the Flinders Sensitive Line rat model of depression. Behavioural brain research. vol 364. 2020-02-13. PMID:30738101. |
compared to frl rats, fsls had lower liver sam, higher plasma serotonin, lower hippocampal dopamine and serotonin turnover, and faster gi transit. |
2020-02-13 |
2023-08-13 |
rat |
| Joneth Fernandes, Girdhari Lal Gupt. N-acetylcysteine attenuates neuroinflammation associated depressive behavior induced by chronic unpredictable mild stress in rat. Behavioural brain research. vol 364. 2020-02-13. PMID:30772427. |
moreover, the levels of pro-inflammatory cytokines in the hippocampus as well as pre-frontal cortex were suppressed, and remarkably restored the serotonin levels by nac (50 and 100 mg/kg, p.o.) |
2020-02-13 |
2023-08-13 |
rat |
| Lokesh Agrawal, Sunil Kumar Vimal, Takashi Shig. Corrigendum to 'Role of serotonin 4 receptor in the growth of hippocampal neurons during the embryonic development in mice'. Neuropharmacology. vol 165. 2020-02-10. PMID:31928879. |
corrigendum to 'role of serotonin 4 receptor in the growth of hippocampal neurons during the embryonic development in mice'. |
2020-02-10 |
2023-08-13 |
mouse |
| Xue-Mei Han, Yan-Jie Qin, Ying Zhu, Xin-Lin Zhang, Nan-Xi Wang, Ying Rang, Xue-Jia Zhai, Yong-Ning L. Development of an underivatized LC-MS/MS method for quantitation of 14 neurotransmitters in rat hippocampus, plasma and urine: Application to CUMS induced depression rats. Journal of pharmaceutical and biomedical analysis. vol 174. 2020-02-06. PMID:31288191. |
a series of significant changes in cums-induced rats can be detected: tryptophan, serotonin and tyrosine levels decreased and quinolinic acid increased in both hippocampus and plasma. |
2020-02-06 |
2023-08-13 |
rat |
| Kuang-Dai Li, Kuo Yan, Qiang-Song Wang, Jun-Sheng Tian, Dong Xu, Wen-Yan Zhang, Yuan-Lu Cu. Antidepressant-like effects of dietary gardenia blue pigment derived from genipin and tyrosine. Food & function. vol 10. issue 8. 2020-02-05. PMID:31264676. |
gtd increased serotonin (5-ht), dopamine (da), and norepinephrine (ne) in rat hippocampus and corpus striatum. |
2020-02-05 |
2023-08-13 |
mouse |
| Shijia Li, Jun Tang, Yan Gao, Christiane M Thiel, Oliver T Wol. The serotonin transporter gene variants modulate acute stress-induced hippocampus and dorsomedial prefrontal cortex activity during memory retrieval. PsyCh journal. vol 8. issue 3. 2020-02-03. PMID:31264389. |
the serotonin transporter gene variants modulate acute stress-induced hippocampus and dorsomedial prefrontal cortex activity during memory retrieval. |
2020-02-03 |
2023-08-13 |
human |
| Shijia Li, Jun Tang, Yan Gao, Christiane M Thiel, Oliver T Wol. The serotonin transporter gene variants modulate acute stress-induced hippocampus and dorsomedial prefrontal cortex activity during memory retrieval. PsyCh journal. vol 8. issue 3. 2020-02-03. PMID:31264389. |
our results thus add new evidence that serotonin signaling modulates neural activity in the hippocampus and dmpfc during memory retrieval under acute psychosocial stress. |
2020-02-03 |
2023-08-13 |
human |