| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K F Martin, S Hannon, I Phillips, D J Hea. Opposing roles for 5-HT1B and 5-HT3 receptors in the control of 5-HT release in rat hippocampus in vivo. British journal of pharmacology. vol 106. issue 1. 1992-09-22. PMID:1504723. |
when infused into the hippocampus for 15 min, the selective 5-ht3 receptor agonist, 2-methyl-5-hydroxytryptamine (2-methyl-5-ht; 0.1- 10 microm) increased dialysate 5-ht levels in a concentration-related manner; an effect which was abolished by concurrent infusion of 3-tropanyl-3,5-dichlorobenzoate (1 microm, mdl 72222), a selective 5-ht3 antagonist. |
1992-09-22 |
2023-08-11 |
rat |
| K F Martin, S Hannon, I Phillips, D J Hea. Opposing roles for 5-HT1B and 5-HT3 receptors in the control of 5-HT release in rat hippocampus in vivo. British journal of pharmacology. vol 106. issue 1. 1992-09-22. PMID:1504723. |
mdl 72222 had no effects on hippocampal 5-ht release when administered via the dialysis probe (1 or 10 microm). |
1992-09-22 |
2023-08-11 |
rat |
| K F Martin, S Hannon, I Phillips, D J Hea. Opposing roles for 5-HT1B and 5-HT3 receptors in the control of 5-HT release in rat hippocampus in vivo. British journal of pharmacology. vol 106. issue 1. 1992-09-22. PMID:1504723. |
the data show that 5-ht3 and 5-ht1b receptors have opposing roles in the control of 5-ht release in the hippocampus, with 5-ht3 receptors facilitating and 5-ht1b receptors inhibiting 5-ht efflux, respectively. |
1992-09-22 |
2023-08-11 |
rat |
| S Caccia, A Bizzi, G Coltro, C Fracasso, E Frittoli, T Mennini, S Garattin. Anorectic activity of fluoxetine and norfluoxetine in rats: relationship between brain concentrations and in-vitro potencies on monoaminergic mechanisms. The Journal of pharmacy and pharmacology. vol 44. issue 3. 1992-09-18. PMID:1354734. |
these results together with recent in-vitro findings that the parent compound and its active metabolite induce tritium release from hippocampal synaptosomes previously loaded with [3h]5-ht suggest that mechanisms other than inhibition of 5-ht uptake are involved in the anorectic action of these compounds in rats. |
1992-09-18 |
2023-08-11 |
rat |
| M Joëls, E R De Kloe. Coordinative mineralocorticoid and glucocorticoid receptor-mediated control of responses to serotonin in rat hippocampus. Neuroendocrinology. vol 55. issue 3. 1992-09-15. PMID:1323803. |
coordinative mineralocorticoid and glucocorticoid receptor-mediated control of responses to serotonin in rat hippocampus. |
1992-09-15 |
2023-08-11 |
rat |
| M Joëls, E R De Kloe. Coordinative mineralocorticoid and glucocorticoid receptor-mediated control of responses to serotonin in rat hippocampus. Neuroendocrinology. vol 55. issue 3. 1992-09-15. PMID:1323803. |
in a previous study we showed that selective occupation of the mineralocorticoid receptor (mr) in hippocampal slices from adrenalectomized (adx) rats attenuates the membrane hyperpolarization and resistance decrease induced in ca1 pyramidal neurons by serotonin (5ht). |
1992-09-15 |
2023-08-11 |
rat |
| M Joëls, E R De Kloe. Coordinative mineralocorticoid and glucocorticoid receptor-mediated control of responses to serotonin in rat hippocampus. Neuroendocrinology. vol 55. issue 3. 1992-09-15. PMID:1323803. |
in the present study we established responses to 5ht in the hippocampal slice when not only mrs but also glucocorticoid receptors (grs) were occupied, using either a combination of selective mr and gr ligands or different concentrations of the endogenous mixed agonist corticosterone. |
1992-09-15 |
2023-08-11 |
rat |
| K E Sabol, J B Richards, L S Seide. The NMDA receptor antagonist MK-801 does not protect against serotonin depletions caused by high doses of DL-fenfluramine. Brain research. vol 582. issue 1. 1992-09-14. PMID:1386771. |
mk-801 + fen did not protect against fen-induced 5ht depletions in nucleus accumbens/olfactory tubercle, septum, frontal cortex, somatosensory cortex or hippocampus. |
1992-09-14 |
2023-08-11 |
rat |
| P W Burnet, I N Mefford, C C Smith, P W Gold, E M Sternber. Hippocampal 8-[3H]hydroxy-2-(di-n-propylamino) tetralin binding site densities, serotonin receptor (5-HT1A) messenger ribonucleic acid abundance, and serotonin levels parallel the activity of the hypothalamopituitary-adrenal axis in rat. Journal of neurochemistry. vol 59. issue 3. 1992-09-09. PMID:1379629. |
hippocampal 8-[3h]hydroxy-2-(di-n-propylamino) tetralin binding site densities, serotonin receptor (5-ht1a) messenger ribonucleic acid abundance, and serotonin levels parallel the activity of the hypothalamopituitary-adrenal axis in rat. |
1992-09-09 |
2023-08-11 |
rat |
| P W Burnet, I N Mefford, C C Smith, P W Gold, E M Sternber. Hippocampal 8-[3H]hydroxy-2-(di-n-propylamino) tetralin binding site densities, serotonin receptor (5-HT1A) messenger ribonucleic acid abundance, and serotonin levels parallel the activity of the hypothalamopituitary-adrenal axis in rat. Journal of neurochemistry. vol 59. issue 3. 1992-09-09. PMID:1379629. |
levels of hippocampal 5-ht in fischer f344/n rats were significantly greater than levels detected in the same regions from lewis and harlan sprague dawley rats. |
1992-09-09 |
2023-08-11 |
rat |
| P W Burnet, I N Mefford, C C Smith, P W Gold, E M Sternber. Hippocampal 8-[3H]hydroxy-2-(di-n-propylamino) tetralin binding site densities, serotonin receptor (5-HT1A) messenger ribonucleic acid abundance, and serotonin levels parallel the activity of the hypothalamopituitary-adrenal axis in rat. Journal of neurochemistry. vol 59. issue 3. 1992-09-09. PMID:1379629. |
we conclude that hippocampal 5-ht1a receptor densities and 5-ht levels in the rat parallel the activity and responsiveness of the hypothalamopituitary-adrenal axis. |
1992-09-09 |
2023-08-11 |
rat |
| R L Sherry-McKenna, G B Baker, D D Mousseau, R T Coutts, W G Dewhurs. 4-Methoxytranylcypromine, a monoamine oxidase inhibitor: effects on biogenic amines in rat brain following chronic administration. Biological psychiatry. vol 31. issue 9. 1992-09-02. PMID:1353376. |
meotcp produced a marked increase in 5-hydroxytryptamine levels in pons-medulla, hypothalamus, and hippocampus relative to values in vehicle-treated rats and also produced a significant increase in these levels over those observed in the tcp-treated rats. |
1992-09-02 |
2023-08-11 |
rat |
| L O Wilkinson, D N Middlemis. Metitepine distinguishes two receptors mediating inhibition of [3H]-5-hydroxytryptamine release in guinea pig hippocampus. Naunyn-Schmiedeberg's archives of pharmacology. vol 345. issue 6. 1992-08-24. PMID:1321958. |
the present study uses this model, in slices of the guinea pig hippocampus, to examine the antagonist potency of metitepine against the 5-ht receptor agonists sumatriptan, 5-carboxamidotryptamine (5-ct) and 5-ht. |
1992-08-24 |
2023-08-11 |
Not clear |
| J R Seckl, G Fin. Antidepressants increase glucocorticoid and mineralocorticoid receptor mRNA expression in rat hippocampus in vivo. Neuroendocrinology. vol 55. issue 6. 1992-08-20. PMID:1321353. |
serotoninergic (5-ht) and noradrenergic projections innervate the hippocampus, interacting with corticosteroid-sensitive cells. |
1992-08-20 |
2023-08-11 |
rat |
| J R Seckl, G Fin. Antidepressants increase glucocorticoid and mineralocorticoid receptor mRNA expression in rat hippocampus in vivo. Neuroendocrinology. vol 55. issue 6. 1992-08-20. PMID:1321353. |
we have previously demonstrated that lesions of 5-ht neurons reduce hippocampal gr and mr mrna levels and now examine whether acute or chronic treatment with antidepressant drugs, which potentiate endogenous monoamines by inhibiting their reuptake, affect hippocampal gr and mr mrna expression in vivo. |
1992-08-20 |
2023-08-11 |
rat |
| I A Pullar, J D Findla. Effect of voltage-sensitive calcium channel antagonists on the release of 5-hydroxytryptamine from rat hippocampus in vivo. Journal of neurochemistry. vol 59. issue 2. 1992-08-20. PMID:1629728. |
effect of voltage-sensitive calcium channel antagonists on the release of 5-hydroxytryptamine from rat hippocampus in vivo. |
1992-08-20 |
2023-08-11 |
rat |
| I A Pullar, J D Findla. Effect of voltage-sensitive calcium channel antagonists on the release of 5-hydroxytryptamine from rat hippocampus in vivo. Journal of neurochemistry. vol 59. issue 2. 1992-08-20. PMID:1629728. |
the effect of calcium channel antagonists on the release of 5-hydroxytryptamine from the hippocampus of the chloral hydrate-anaesthetised rat was studied using the technique of intracerebral microdialysis. |
1992-08-20 |
2023-08-11 |
rat |
| I A Pullar, J D Findla. Effect of voltage-sensitive calcium channel antagonists on the release of 5-hydroxytryptamine from rat hippocampus in vivo. Journal of neurochemistry. vol 59. issue 2. 1992-08-20. PMID:1629728. |
it is concluded that, under physiological conditions, the release of 5-hydroxytryptamine from the rat hippocampus is dependent on the entry of calcium through n-type voltage-sensitive calcium channels, although another calcium channel may also be involved. |
1992-08-20 |
2023-08-11 |
rat |
| J W Wei, M J Lee, S R Ye. Biochemical events coupled to the activation of serotonin receptors in brain regions of the rat. The Chinese journal of physiology. vol 34. issue 4. 1992-08-10. PMID:1668198. |
when brain slices were treated with serotonin (10(-4) or 10(-5) m), it caused significant increases in inositol phosphate levels in cerebral cortex, hippocampus, midbrain and brain stem, but not in cerebellum. |
1992-08-10 |
2023-08-11 |
rat |
| J W Wei, M J Lee, S R Ye. Biochemical events coupled to the activation of serotonin receptors in brain regions of the rat. The Chinese journal of physiology. vol 34. issue 4. 1992-08-10. PMID:1668198. |
however, serotonin also had significant inhibitory effect on forskolin-induced camp formation in cerebral cortex, hippocampus and brain stem but not in midbrain in which an increase instead. |
1992-08-10 |
2023-08-11 |
rat |