| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Caccia, C Fracasso, S Garattini, G Guiso, S Sarat. Effects of short- and long-term administration of fluoxetine on the monoamine content of rat brain. Neuropharmacology. vol 31. issue 4. 1992-10-09. PMID:1381817. |
the content of indoles remained significantly decreased for at least a week after the last dose of fluoxetine in the 21-day regimen, although the concentrations of 5-hiaa (but not 5-ht) totally recovered at the smaller dose (7.5 mg/kg) in all regions of the brain (cortex, hippocampus and striatum). |
1992-10-09 |
2023-08-11 |
rat |
| E Edwards, W Kornrich, P V Houtten, F A Hen. Presynaptic serotonin mechanisms in rats subjected to inescapable shock. Neuropharmacology. vol 31. issue 4. 1992-10-09. PMID:1387924. |
in the hippocampus, these included a statistically significant increase in three presynaptic 5-hydroxytryptamine (5-ht) mechanisms: k(+)-induced release of [3h]serotonin, high affinity uptake of [3h]serotonin and maximum density of binding sites for uptake of 5-ht, measured with [3h]paroxetine. |
1992-10-09 |
2023-08-11 |
rat |
| U Freo, H W Holloway, K Kalogeras, S I Rapoport, T T Soncran. Adrenalectomy or metyrapone-pretreatment abolishes cerebral metabolic responses to the serotonin agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) in the hippocampus. Brain research. vol 586. issue 2. 1992-10-09. PMID:1521159. |
adrenalectomy or metyrapone-pretreatment abolishes cerebral metabolic responses to the serotonin agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (doi) in the hippocampus. |
1992-10-09 |
2023-08-11 |
rat |
| U Freo, H W Holloway, K Kalogeras, S I Rapoport, T T Soncran. Adrenalectomy or metyrapone-pretreatment abolishes cerebral metabolic responses to the serotonin agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) in the hippocampus. Brain research. vol 586. issue 2. 1992-10-09. PMID:1521159. |
1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (doi), a serotonin type 2 (5-ht2) agonist, elevates plasma corticosterone levels and reduces the cerebral metabolic rate for glucose (rcmrglc) in the hippocampus, a structure which possesses few 5-ht2 receptors but a large number of steroid receptors. |
1992-10-09 |
2023-08-11 |
rat |
| U Freo, H W Holloway, K Kalogeras, S I Rapoport, T T Soncran. Adrenalectomy or metyrapone-pretreatment abolishes cerebral metabolic responses to the serotonin agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) in the hippocampus. Brain research. vol 586. issue 2. 1992-10-09. PMID:1521159. |
to explore the hypothetical interaction between 5-ht and steroid mechanisms in the hippocampus, we measured rcmrglc in intact, adrenalectomized and metyrapone-pretreated rats after saline or doi administration. |
1992-10-09 |
2023-08-11 |
rat |
| O G Nilsson, G Leanza, A Björklun. Acetylcholine release in the hippocampus: regulation by monoaminergic afferents as assessed by in vivo microdialysis. Brain research. vol 584. issue 1-2. 1992-10-07. PMID:1355389. |
the serotonin-releasing agent p-chloroamphetamine (2.5 mg/kg) produced a 160% increase in hippocampal ach release, and this effect was enhanced after a 5,7-dihydroxytryptamine (5,7-dht) lesion of the serotonin projection system. |
1992-10-07 |
2023-08-11 |
rat |
| X C Li, H D Li, B Y Zhao, H Z Hua. [Effect of intraventricular injection of somatostatin on pain threshold, and contents of the monoamines, xanthine, hypoxanthine in rats brain]. Zhongguo yao li xue bao = Acta pharmacologica Sinica. vol 12. issue 6. 1992-10-07. PMID:1688090. |
using hplc with electrochemical detection, we found that icv somatostatin (som) 5 or 10 micrograms increased rat's pain threshold and contents of 5-ht and 5-hiaa in hippocampus, hypothalamus and brainstem, except the 5-hiaa content of brainstem in som 5 micrograms group. |
1992-10-07 |
2023-08-11 |
rat |
| R H Amundson, S K Goderie, H K Kimelber. Uptake of [3H]serotonin and [3H]glutamate by primary astrocyte cultures. II. Differences in cultures prepared from different brain regions. Glia. vol 6. issue 1. 1992-09-30. PMID:1355075. |
the relative order of uptake for [3h] 5-ht was ms (mesencephalon) greater than cc (cerebral cortex) greater than bg + di (basal ganglia + diencephalon) greater than hp (hippocampus) greater than bs (brain stem) greater than cb (cerebellum). |
1992-09-30 |
2023-08-11 |
rat |
| J C Cassel, B Neufang, C Kelche, F Aiple, B E Will, G Hertting, R Jackisc. Effects of septal and/or raphe cell suspension grafts on hippocampal choline acetyltransferase activity, high affinity synaptosomal uptake of choline and serotonin, and behavior in rats with extensive septohippocampal lesions. Brain research. vol 585. issue 1-2. 1992-09-29. PMID:1511308. |
effects of septal and/or raphe cell suspension grafts on hippocampal choline acetyltransferase activity, high affinity synaptosomal uptake of choline and serotonin, and behavior in rats with extensive septohippocampal lesions. |
1992-09-29 |
2023-08-11 |
rat |
| J C Cassel, B Neufang, C Kelche, F Aiple, B E Will, G Hertting, R Jackisc. Effects of septal and/or raphe cell suspension grafts on hippocampal choline acetyltransferase activity, high affinity synaptosomal uptake of choline and serotonin, and behavior in rats with extensive septohippocampal lesions. Brain research. vol 585. issue 1-2. 1992-09-29. PMID:1511308. |
the lesions increased locomotor activity, impaired radial maze learning and, in the dorsal hippocampus, reduced ache positive staining, decreased chat activity (-73%) as well as high affinity uptake of both choline (-81%) and serotonin (-82%). |
1992-09-29 |
2023-08-11 |
rat |
| J C Cassel, B Neufang, C Kelche, F Aiple, B E Will, G Hertting, R Jackisc. Effects of septal and/or raphe cell suspension grafts on hippocampal choline acetyltransferase activity, high affinity synaptosomal uptake of choline and serotonin, and behavior in rats with extensive septohippocampal lesions. Brain research. vol 585. issue 1-2. 1992-09-29. PMID:1511308. |
however, septal transplants increased hippocampal ache positivity, restored chat activity and enhanced choline uptake to 116% and 70% of the values found in sham-operated rats, respectively; they had no significant effect on uptake of serotonin. |
1992-09-29 |
2023-08-11 |
rat |
| J C Cassel, B Neufang, C Kelche, F Aiple, B E Will, G Hertting, R Jackisc. Effects of septal and/or raphe cell suspension grafts on hippocampal choline acetyltransferase activity, high affinity synaptosomal uptake of choline and serotonin, and behavior in rats with extensive septohippocampal lesions. Brain research. vol 585. issue 1-2. 1992-09-29. PMID:1511308. |
transplants from the raphe region had weak effects on hippocampal ache positivity, increased both the chat activity and the choline uptake to 70% ad 38% of the sham-operated rats, respectively, and produced an (over)compensation of the serotonin uptake which reached 324% of the values found in sham-operated rats. |
1992-09-29 |
2023-08-11 |
rat |
| T Hiros. [Effects of nutritional status on contents of tryptophan, serotonin and 5-hydroxyindoleacetic acid in rat brain]. Nihon eiseigaku zasshi. Japanese journal of hygiene. vol 47. issue 2. 1992-09-25. PMID:1380998. |
1) a low-protein high-carbohydrate diet decreased trp, 5ht and 5hiaa levels in the cortex and hippocampus, and those of 5ht and 5hiaa in the hypothalamus. |
1992-09-25 |
2023-08-11 |
rat |
| T Hiros. [Effects of nutritional status on contents of tryptophan, serotonin and 5-hydroxyindoleacetic acid in rat brain]. Nihon eiseigaku zasshi. Japanese journal of hygiene. vol 47. issue 2. 1992-09-25. PMID:1380998. |
2) a low-carbohydrate high-protein diet increased the levels of trp, 5ht and 5hiaa in the striatum, and 5ht and 5hiaa in the cortex, but showed no effect on the contents of trp, 5ht and 5hiaa in the hippocampus, midbrain, pons and medulla and hypothalamus. |
1992-09-25 |
2023-08-11 |
rat |
| T Hiros. [Effects of nutritional status on contents of tryptophan, serotonin and 5-hydroxyindoleacetic acid in rat brain]. Nihon eiseigaku zasshi. Japanese journal of hygiene. vol 47. issue 2. 1992-09-25. PMID:1380998. |
the diet did not influence trp, 5ht and 5hiaa contents of the midbrain and hippocampus. |
1992-09-25 |
2023-08-11 |
rat |
| T Hiros. [Effects of nutritional status on contents of tryptophan, serotonin and 5-hydroxyindoleacetic acid in rat brain]. Nihon eiseigaku zasshi. Japanese journal of hygiene. vol 47. issue 2. 1992-09-25. PMID:1380998. |
these results suggest that i) lowered fat and carbohydrate intakes enhance 5ht synthesis and metabolism in the cortex and that lowered carbohydrate intake enhances them in the striatum, ii) energy restriction enhances the 5ht metabolism in the cortex, pons and medulla and hypothalamus, and 5ht synthesis in the cortex and pons and medulla, iii) lowered protein intake inhibits 5ht metabolism in the cortex, midbrain, hippocampus and hypothalamus, and 5ht synthesis in the cortex, hippocampus and hypothalamus. |
1992-09-25 |
2023-08-11 |
rat |
| Y Wada, M Nakamura, H Hasegawa, N Yamaguch. Role of serotonin receptor subtype in seizures kindled from the feline hippocampus. Neuroscience letters. vol 141. issue 1. 1992-09-22. PMID:1387198. |
this study assessed the effects of a serotonin (5-ht)1a agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat), a 5-ht2 agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (doi) and a 5-ht2 antagonist ketanserin on fully kindled seizures from the hippocampus. |
1992-09-22 |
2023-08-11 |
Not clear |
| Y Wada, M Nakamura, H Hasegawa, N Yamaguch. Role of serotonin receptor subtype in seizures kindled from the feline hippocampus. Neuroscience letters. vol 141. issue 1. 1992-09-22. PMID:1387198. |
8-oh-dpat produced a marked suppression in hippocampal kindled seizures, while producing behavioral signs similar to those seen in the 5-ht syndrome. |
1992-09-22 |
2023-08-11 |
Not clear |
| K F Martin, S Hannon, I Phillips, D J Hea. Opposing roles for 5-HT1B and 5-HT3 receptors in the control of 5-HT release in rat hippocampus in vivo. British journal of pharmacology. vol 106. issue 1. 1992-09-22. PMID:1504723. |
opposing roles for 5-ht1b and 5-ht3 receptors in the control of 5-ht release in rat hippocampus in vivo. |
1992-09-22 |
2023-08-11 |
rat |
| K F Martin, S Hannon, I Phillips, D J Hea. Opposing roles for 5-HT1B and 5-HT3 receptors in the control of 5-HT release in rat hippocampus in vivo. British journal of pharmacology. vol 106. issue 1. 1992-09-22. PMID:1504723. |
intracerebral microdialysis was used to determine whether 5-hydroxytryptamine (5-ht) release in the ventral hippocampus of rats anaesthetized with chloral hydrate was modulated by 5-ht3 receptors. |
1992-09-22 |
2023-08-11 |
rat |