| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G J Blatt, J C Chen, D L Rosene, L Volicer, J R Galle. Prenatal protein malnutrition effects on the serotonergic system in the hippocampal formation: an immunocytochemical, ligand binding, and neurochemical study. Brain research bulletin. vol 34. issue 5. 1994-10-13. PMID:8082044. |
considering the 5-ht afferent input to inhibitory intrahippocampal neurons, the decreased 5-ht plexus may result in increased inhibition within specific hippocampal subfields despite overall normal levels of 5-ht in the total hf. |
1994-10-13 |
2023-08-12 |
rat |
| A Singh, P Redfer. Lack of circadian variation in the sensitivity of rat terminal 5-HT1B autoreceptors. The Journal of pharmacy and pharmacology. vol 46. issue 5. 1994-10-13. PMID:8083808. |
the sensitivity of terminal 5-ht1b autoreceptors in the cerebral cortex and hippocampus to both agonist and antagonist was determined at four different time points in the light:dark cycle of the rat to evaluate whether changes in their responsiveness underlie the circadian rhythm in 5-hydroxytryptamine (5-ht) release. |
1994-10-13 |
2023-08-12 |
rat |
| A Singh, P Redfer. Lack of circadian variation in the sensitivity of rat terminal 5-HT1B autoreceptors. The Journal of pharmacy and pharmacology. vol 46. issue 5. 1994-10-13. PMID:8083808. |
these findings suggest that the sensitivity of terminal 5-ht1b autoreceptors in rat cerebral cortex and hippocampus does not change in a circadian pattern, during the light:dark cycle, and argues against such a change influencing the circadian variation in 5-ht release. |
1994-10-13 |
2023-08-12 |
rat |
| C Bendotti, S Baldessari, M Pende, G Tarizzo, A Miari, M L Presti, T Mennini, R Samani. Does GFAP mRNA and mitochondrial benzodiazepine receptor binding detect serotonergic neuronal degeneration in rat? Brain research bulletin. vol 34. issue 4. 1994-10-11. PMID:8082031. |
intracerebroventricularly (icv) injected 5,7-dihydroxytryptamine (5,7-dht), which reduced by 70-90% forebrain serotonin levels, significantly raised glial fibrillary acidic protein (gfap) mrna levels in the hippocampus and nucleus raphe dorsalis 5 days but not 15 days after the lesion. |
1994-10-11 |
2023-08-12 |
rat |
| C Bendotti, S Baldessari, M Pende, G Tarizzo, A Miari, M L Presti, T Mennini, R Samani. Does GFAP mRNA and mitochondrial benzodiazepine receptor binding detect serotonergic neuronal degeneration in rat? Brain research bulletin. vol 34. issue 4. 1994-10-11. PMID:8082031. |
unlike the icv route, bilateral injection of 5,7-dht into the medial forebrain bundle, which caused a 65-90% reduction of serotonin levels in different forebrain regions, significantly raised gfap mrna and mbr binding only at the site of injection with no effect in hippocampus, striatum, and cortex. |
1994-10-11 |
2023-08-12 |
rat |
| P H Wu, J F Liu, A J Lança, H Kalan. Selective involvement of central 5-HT2 receptors in the maintenance of tolerance to ethanol by arginine8-vasopressin. The Journal of pharmacology and experimental therapeutics. vol 270. issue 2. 1994-09-28. PMID:8071872. |
this resulted in a marked decrease in 5-hydroxytryptamine (5-ht) immunoreactivity in the terminal areas of the septum and the hippocampus, but not in the serotonin-containing neuronal cell bodies in the raphe nuclei. |
1994-09-28 |
2023-08-12 |
rat |
| A J Dekker, J Winkler, J Ray, L J Thal, F H Gag. Grafting of nerve growth factor-producing fibroblasts reduces behavioral deficits in rats with lesions of the nucleus basalis magnocellularis. Neuroscience. vol 60. issue 2. 1994-09-23. PMID:8072685. |
levels of norepinephrine, epinephrine and serotonin and their metabolites in the neocortex and hippocampus were not affected by the lesion or the grafts. |
1994-09-23 |
2023-08-12 |
human |
| K Kaw. Distribution and functional properties of 5-HT3 receptors in the rat hippocampal dentate gyrus: a patch-clamp study. Journal of neurophysiology. vol 71. issue 5. 1994-09-20. PMID:7520482. |
in dentate gyrus of rat hippocampal slices two distinct types of neurons, principal excitatory neurons (granule cells) and local inhibitory neurons (basket cells), could be identified under nomarski microscopy; i investigated the actions of serotonin using the whole-cell patch-clamp technique. |
1994-09-20 |
2023-08-12 |
rat |
| M K Lakshmana, T R Raj. Endosulfan induces small but significant changes in the levels of noradrenaline, dopamine and serotonin in the developing rat brain and deficits in the operant learning performance. Toxicology. vol 91. issue 2. 1994-09-15. PMID:8059438. |
its effect on levels of noradrenaline (na), dopamine (da) and serotonin (5-ht) was assayed in olfactory bulb (ob), hippocampus (hi), visual cortex (vc), brainstem (bs) and cerebellum (cb) on days 10 and 25 using high-performance liquid chromatography (hplc). |
1994-09-15 |
2023-08-12 |
rat |
| D Nakahara, W Maruyama, H Hashiguti, M Nao. Characterization of the in vivo action of (R)-salsolinol, an endogenous metabolite of alcohol, on serotonin and dopamine metabolism: a microdialysis study. Brain research. vol 644. issue 2. 1994-09-08. PMID:8050034. |
using a microdialysis-hplc technique in conscious rats, we examined the action of (r)-1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, (r)-salsolinol (r-sal), a possible endogenous metabolite of alcohol, on serotonin (5-ht) and dopamine (da) metabolism in four regions of the brain: the striatum, the substantia nigra, the hippocampus and the hypothalamus. |
1994-09-08 |
2023-08-12 |
rat |
| F A Dijcks, J H Couvée, G S Ruig. Long-term in vivo desipramine or estrogen treatment fails to affect serotonin-induced outward current in hippocampal pyramidal cells of the rat. Neuroscience. vol 60. issue 1. 1994-09-08. PMID:8052414. |
the effect of castration combined with either long-term treatment with the tricyclic antidepressant drug desipramine or the sex steroid 17 beta-estradiol on serotonin responses in area ca1 of the hippocampus of male and female rats was examined. |
1994-09-08 |
2023-08-12 |
rat |
| P S Whitton, D A Richards, C S Biggs, L J Fowle. N-methyl-D-aspartate receptors modulate extracellular 5-hydroxytryptamine concentration in rat hippocampus and striatum in vivo. Neuroscience letters. vol 169. issue 1-2. 1994-09-01. PMID:7519338. |
n-methyl-d-aspartate receptors modulate extracellular 5-hydroxytryptamine concentration in rat hippocampus and striatum in vivo. |
1994-09-01 |
2023-08-12 |
rat |
| P S Whitton, D A Richards, C S Biggs, L J Fowle. N-methyl-D-aspartate receptors modulate extracellular 5-hydroxytryptamine concentration in rat hippocampus and striatum in vivo. Neuroscience letters. vol 169. issue 1-2. 1994-09-01. PMID:7519338. |
the effects of infusing n-methyl-d-aspartate (nmda) and the specific nmda receptor antagonist d-2-amino-5-phosphonopropionic acid (d-ap5) into rat hippocampus and striatum on extracellular 5-hydroxytryptamine (5-ht) and its metabolite 5-hydroxy-indoleacetic acid (5-hiaa) were studied using intracerebral microdialysis. |
1994-09-01 |
2023-08-12 |
rat |
| P S Whitton, D A Richards, C S Biggs, L J Fowle. N-methyl-D-aspartate receptors modulate extracellular 5-hydroxytryptamine concentration in rat hippocampus and striatum in vivo. Neuroscience letters. vol 169. issue 1-2. 1994-09-01. PMID:7519338. |
in hippocampus, nmda infusion caused a dose-dependent decrease in extracellular 5-ht while d-ap5 produced a transitory increase in 5-ht level. |
1994-09-01 |
2023-08-12 |
rat |
| K Kawai, N Yokota, S Yamawak. Effect of chronic tryptophan depletion on the circadian rhythm of wheel-running activity in rats. Physiology & behavior. vol 55. issue 6. 1994-08-30. PMID:7519351. |
a long-term trp-fre diet decreased the concentration of trp, 5-hydroxytryptamine (5-ht), and 5-hydroxyindoleacetic acid (5-hiaa) in all brain regions tested: frontal cortex, hippocampus, thalamus, hypothalamus, midbrain, and pons. |
1994-08-30 |
2023-08-12 |
rat |
| A C Linthorst, C Flachskamm, F Holsboer, J M Reu. Local administration of recombinant human interleukin-1 beta in the rat hippocampus increases serotonergic neurotransmission, hypothalamic-pituitary-adrenocortical axis activity, and body temperature. Endocrinology. vol 135. issue 2. 1994-08-18. PMID:7518383. |
in control rats, there was a clear relationship between extracellular 5-ht concentrations in the hippocampus and behavioral activity. |
1994-08-18 |
2023-08-12 |
human |
| A C Linthorst, C Flachskamm, F Holsboer, J M Reu. Local administration of recombinant human interleukin-1 beta in the rat hippocampus increases serotonergic neurotransmission, hypothalamic-pituitary-adrenocortical axis activity, and body temperature. Endocrinology. vol 135. issue 2. 1994-08-18. PMID:7518383. |
intrahippocampal administration of hil-1 beta markedly increased extracellular 5-ht concentrations in the hippocampus and induced a significant decrease in behavioral activity, thereby uncoupling the parallelism between changes in 5-ht and changes in behavioral activity observed in control rats. |
1994-08-18 |
2023-08-12 |
human |
| S Zalcman, J M Green-Johnson, L Murray, D M Nance, D Dyck, H Anisman, A H Greenber. Cytokine-specific central monoamine alterations induced by interleukin-1, -2 and -6. Brain research. vol 643. issue 1-2. 1994-08-12. PMID:7518332. |
in particular, il-1 enhanced ne turnover in the hypothalamus and hippocampus, 5-ht turnover in the hippocampus and prefrontal cortex (owing to increased utilization and reduced content of the transmitters in these brain regions), and enhanced da utilization in the prefrontal cortex. |
1994-08-12 |
2023-08-12 |
mouse |
| S Zalcman, J M Green-Johnson, L Murray, D M Nance, D Dyck, H Anisman, A H Greenber. Cytokine-specific central monoamine alterations induced by interleukin-1, -2 and -6. Brain research. vol 643. issue 1-2. 1994-08-12. PMID:7518332. |
il-6 increased 5-ht and da activity in the hippocampus and prefrontal cortex in a manner similar to il-1, but failed to affect central ne activity. |
1994-08-12 |
2023-08-12 |
mouse |
| A P Tsou, A Kosaka, C Bach, P Zuppan, C Yee, L Tom, R Alvarez, S Ramsey, D W Bonhaus, E Stefanic. Cloning and expression of a 5-hydroxytryptamine7 receptor positively coupled to adenylyl cyclase. Journal of neurochemistry. vol 63. issue 2. 1994-08-12. PMID:7518496. |
a cdna clone (designated as gp2-7) encoding a novel 5-hydroxytryptamine (5-ht) receptor was isolated from a guinea pig hippocampal library. |
1994-08-12 |
2023-08-12 |
rat |