| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I K Wright, N Upton, C A Marsde. Effect of established and putative anxiolytics on extracellular 5-HT and 5-HIAA in the ventral hippocampus of rats during behaviour on the elevated X-maze. Psychopharmacology. vol 109. issue 3. 1995-02-14. PMID:1285416. |
forty minutes pretreatment with the .5-ht1a receptor partial agonist ipsapirone (1 mg kg-1 ip) significantly inhibited the increase in extracellular 5-ht in the ventral hippocampus but did not produce behaviour different from vehicle controls after 5 or 20 min periods on the x-maze. |
1995-02-14 |
2023-08-11 |
rat |
| M Yamazaki, N Matsuoka, N Maeda, K Kuratani, Y Ohkubo, I Yamaguch. FR121196, a potential antidementia drug, ameliorates the impaired memory of rat in the Morris water maze. The Journal of pharmacology and experimental therapeutics. vol 272. issue 1. 1995-02-08. PMID:7815340. |
neurochemical analysis of the brain showed that dopamine, norepinephrine and serotonin levels were significantly reduced in the hippocampus of the ff-lesioned rats compared with the sham control, and a significant reduction of dopamine level in the cortex was also observed in the aged rats compared with young rats. |
1995-02-08 |
2023-08-12 |
rat |
| M Iu Antipina, I V Kudriashov, A A Folomkina, R I Krugliko. [The effect of serotonin on the rate of plastic processes in the hippocampus]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 44. issue 4-5. 1995-01-27. PMID:7810230. |
[the effect of serotonin on the rate of plastic processes in the hippocampus]. |
1995-01-27 |
2023-08-12 |
Not clear |
| B Budziszewska, J Siwanowicz, E Przegalińsk. The effect of chronic treatment with antidepressant drugs on the corticosteroid receptor levels in the rat hippocampus. Polish journal of pharmacology. vol 46. issue 3. 1995-01-25. PMID:8000446. |
the effect of long-term (28 days) treatment with desipramine, (+)-oxaprotiline (selective inhibitors of the noradrenaline - na - uptake), citalopram (a selective inhibitor of the serotonine - 5-ht - uptake) and mianserin (an atypical antidepressant drug, devoid of an effect on the monoamine uptake) on the binding parameters of corticosteroid receptors was studied in the rat hippocampus. |
1995-01-25 |
2023-08-12 |
rat |
| M Bijak, K Tokarsk. Prolonged administration of imipramine and (+)-oxaprotiline, but not citalopram, results in sensitization of the rat hippocampal CA1 neurons to serotonin ex vivo. Polish journal of pharmacology. vol 46. issue 3. 1995-01-25. PMID:8000448. |
prolonged (14 days, twice daily), but not acute, application of imipramine and (+)-oxaprotiline (10 mg/kg) induced sensitization of hippocampal ca1 neurons to the inhibitory effect of 5-hydroxytryptamine (5-ht), as studied ex vivo in the rat hippocampal slice preparation. |
1995-01-25 |
2023-08-12 |
rat |
| M Bijak, K Tokarsk. Prolonged administration of imipramine and (+)-oxaprotiline, but not citalopram, results in sensitization of the rat hippocampal CA1 neurons to serotonin ex vivo. Polish journal of pharmacology. vol 46. issue 3. 1995-01-25. PMID:8000448. |
prolonged and acute administration of the selective 5-ht reuptake blocker citalopram did not change the responsiveness of hippocampal neurons to 5-ht. |
1995-01-25 |
2023-08-12 |
rat |
| L Rouquier, Y Claustre, J Benavide. Alpha 1-adrenoceptor antagonists differentially control serotonin release in the hippocampus and striatum: a microdialysis study. European journal of pharmacology. vol 261. issue 1-2. 1995-01-23. PMID:8001654. |
alpha 1-adrenoceptor antagonists differentially control serotonin release in the hippocampus and striatum: a microdialysis study. |
1995-01-23 |
2023-08-12 |
rat |
| L Rouquier, Y Claustre, J Benavide. Alpha 1-adrenoceptor antagonists differentially control serotonin release in the hippocampus and striatum: a microdialysis study. European journal of pharmacology. vol 261. issue 1-2. 1995-01-23. PMID:8001654. |
using the in vivo microdialysis technique, we have studied the effect of the systemic administration of several alpha 1-adrenoceptor antagonists on the extracellular levels of serotonin (5-ht) in the rat hippocampus. |
1995-01-23 |
2023-08-12 |
rat |
| L Rouquier, Y Claustre, J Benavide. Alpha 1-adrenoceptor antagonists differentially control serotonin release in the hippocampus and striatum: a microdialysis study. European journal of pharmacology. vol 261. issue 1-2. 1995-01-23. PMID:8001654. |
when perfused into the hippocampus through the dialysis probe, prazosin (1-10 microm) induced a more limited (20-30%) and delayed decrease in 5-ht outflow. |
1995-01-23 |
2023-08-12 |
rat |
| L Rouquier, Y Claustre, J Benavide. Alpha 1-adrenoceptor antagonists differentially control serotonin release in the hippocampus and striatum: a microdialysis study. European journal of pharmacology. vol 261. issue 1-2. 1995-01-23. PMID:8001654. |
decreased 5-ht levels to a smaller extent (-35%) than in the hippocampus (-65%), suggesting the existence of differences in the degree of noradrenergic influence on median and dorsal raphé nuclei, which preferentially project to the hippocampus and striatum, respectively. |
1995-01-23 |
2023-08-12 |
rat |
| S Hjorth, S B Auerbac. Further evidence for the importance of 5-HT1A autoreceptors in the action of selective serotonin reuptake inhibitors. European journal of pharmacology. vol 260. issue 2-3. 1995-01-09. PMID:7988652. |
in vivo microdialysis in rat hippocampus was used to assess the release-inhibitory properties of the 5-ht reuptake inhibitors citalopram and paroxetine. |
1995-01-09 |
2023-08-12 |
rat |
| S Hjorth, S B Auerbac. Further evidence for the importance of 5-HT1A autoreceptors in the action of selective serotonin reuptake inhibitors. European journal of pharmacology. vol 260. issue 2-3. 1995-01-09. PMID:7988652. |
when reuptake was first blocked by infusing citalopram into the hippocampus, systemic administration of citalopram or paroxetine resulted in a 50-70% decrease in hippocampal 5-ht overflow. |
1995-01-09 |
2023-08-12 |
rat |
| H Jeltsch, J C Cassel, R Jackisch, B Neufang, P L Greene, C Kelche, G Hertting, B Wil. Lesions of supracallosal or infracallosal hippocampal pathways in the rat: behavioral, neurochemical, and histochemical effects. Behavioral and neural biology. vol 62. issue 2. 1995-01-09. PMID:7993302. |
subsequently, histochemical or neurochemical determinations of cholinergic, serotonergic and noradrenergic hippocampal innervations were performed using acetylcholinesterase-staining, determination of high-affinity synaptosomal uptake of choline and serotonin, and measurement of hippocampal serotonin and noradrenaline concentrations by hplc methods. |
1995-01-09 |
2023-08-12 |
rat |
| C Routledge, J Hartley, J Gurling, M Ashworth-Preece, G Brown, C T Douris. In vivo characterization of the putative 5-HT1A receptor antagonist SDZ 216,525 using two models of somatodendritic 5-HT1A receptor function. Neuropharmacology. vol 33. issue 3-4. 1994-12-30. PMID:7984274. |
sdz 216,525 (1 mg/kg s.c.) and the alpha 1-adrenoceptor antagonist prazosin (1 mg/kg s.c.) significantly decreased hippocampal 5-ht release. |
1994-12-30 |
2023-08-12 |
rat |
| C Routledge, J Hartley, J Gurling, M Ashworth-Preece, G Brown, C T Douris. In vivo characterization of the putative 5-HT1A receptor antagonist SDZ 216,525 using two models of somatodendritic 5-HT1A receptor function. Neuropharmacology. vol 33. issue 3-4. 1994-12-30. PMID:7984274. |
the decrease in hippocampal 5-ht release and increase in food intake induced by sdz 216,525 suggest that the compound may be a 5-ht1a receptor partial agonist. |
1994-12-30 |
2023-08-12 |
rat |
| S Roychowdhury, H Haas, E G Anderso. 5-HT1A and 5-HT4 receptor colocalization on hippocampal pyramidal cells. Neuropharmacology. vol 33. issue 3-4. 1994-12-30. PMID:7984294. |
the mixed inhibitory and excitatory effects of 5-ht on hippocampal pyramidal cells were studied on hippocampal slices perfused with a low-ca2+/high mg2+ solution that blocked synaptic activity and induced spontaneous pyramidal cell discharge. |
1994-12-30 |
2023-08-12 |
Not clear |
| Y Cui, T Lee, L C Wan. Species difference in the modulatory effect of kappa agonist on 5-HT release from ground squirrel and rat hippocampus. Neuroscience letters. vol 175. issue 1-2. 1994-12-29. PMID:7970193. |
species difference in the modulatory effect of kappa agonist on 5-ht release from ground squirrel and rat hippocampus. |
1994-12-29 |
2023-08-12 |
rat |
| Y Cui, T Lee, L C Wan. Species difference in the modulatory effect of kappa agonist on 5-HT release from ground squirrel and rat hippocampus. Neuroscience letters. vol 175. issue 1-2. 1994-12-29. PMID:7970193. |
inclusion of the kappa agonist u50488 in the perifusion medium enhanced k(+)-stimulated 5-ht release from ground squirrel hippocampal slices, but reduced 5-ht outflow in both young and old rats' hippocampal slices. |
1994-12-29 |
2023-08-12 |
rat |
| Y Cui, T Lee, L C Wan. Species difference in the modulatory effect of kappa agonist on 5-HT release from ground squirrel and rat hippocampus. Neuroscience letters. vol 175. issue 1-2. 1994-12-29. PMID:7970193. |
the stimulatory effect of u50488 on 5-ht release from ground squirrel hippocampus was not significantly attenuated by the non-specific opioid antagonist naloxone (10(-5) m), but was completely reversed by the specific kappa antagonist nor-bni (10(-6)m), and the voltage-dependent sodium channel blocker ttx (10(-6)m). |
1994-12-29 |
2023-08-12 |
rat |
| Y Cui, T Lee, L C Wan. Species difference in the modulatory effect of kappa agonist on 5-HT release from ground squirrel and rat hippocampus. Neuroscience letters. vol 175. issue 1-2. 1994-12-29. PMID:7970193. |
in contrast, the inhibitory effect of u50488 on 5-ht release from the young rat hippocampus was attenuated by naloxone (10(-6)m), but not by nor-bni (10(-6)m) or ttx (10(-6)m). |
1994-12-29 |
2023-08-12 |
rat |