| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Numazaw. [Pharmacological characterization of alpha 2-adrenoceptor regulated 5-HT release in the rat hippocampus]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 69. issue 4. 1994-12-28. PMID:7959600. |
[pharmacological characterization of alpha 2-adrenoceptor regulated 5-ht release in the rat hippocampus]. |
1994-12-28 |
2023-08-12 |
rat |
| R Numazaw. [Pharmacological characterization of alpha 2-adrenoceptor regulated 5-HT release in the rat hippocampus]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 69. issue 4. 1994-12-28. PMID:7959600. |
the purpose of the present study is to confirm the functional regulation of alpha 2-adrenoceptor on the release of serotonin (5-ht) from the rat hippocampus in vivo. |
1994-12-28 |
2023-08-12 |
rat |
| R Numazaw. [Pharmacological characterization of alpha 2-adrenoceptor regulated 5-HT release in the rat hippocampus]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 69. issue 4. 1994-12-28. PMID:7959600. |
extracellular 5-ht in the hippocampus was reduced by tetrodotoxin, 10 microm co-perfusion and was increased by perfusion with a selective 5-ht reuptake inhibitor, fluoxetine, 10 microm. |
1994-12-28 |
2023-08-12 |
rat |
| R Numazaw. [Pharmacological characterization of alpha 2-adrenoceptor regulated 5-HT release in the rat hippocampus]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 69. issue 4. 1994-12-28. PMID:7959600. |
potassium-evoked 5-ht release from the hippocampus of freely moving rats was significantly and concentration-dependently inhibited when alpha 2-adrenoceptor agonist, uk14,304, 0.1 microm to 10 microm was added to the perfusion solution, while the output of a 5-ht major metabolite, 5-hydroxyindoleacetic acid (5-hiaa), remained unchanged. |
1994-12-28 |
2023-08-12 |
rat |
| R Numazaw. [Pharmacological characterization of alpha 2-adrenoceptor regulated 5-HT release in the rat hippocampus]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 69. issue 4. 1994-12-28. PMID:7959600. |
these findings suggest that 5-ht release is functionally modulated via alpha 2-adrenoceptors located on the serotonergic nerve terminals in the rat hippocampus. |
1994-12-28 |
2023-08-12 |
rat |
| K Kasamo, K Tada, N Ueda, T Kojima, M Kogure, K Ishikaw. Effects of several 5-HT1A agonists on hippocampal rhythmical slow activity in unanesthetized rats. Neuropharmacology. vol 33. issue 7. 1994-12-28. PMID:7969811. |
we examined the effect of 5-hydroxytryptamine (5-ht)1a agonists on walking related, atropine-resistant, rhythmical slow activity (wr-rsa) of the hippocampus in rats. |
1994-12-28 |
2023-08-12 |
rat |
| F Bosker, A Klompmakers, H Westenber. Extracellular 5-hydroxytryptamine in median raphe nucleus of the conscious rat is decreased by nanomolar concentrations of 8-hydroxy-2-(di-n-propylamino) tetralin and is sensitive to tetrodotoxin. Journal of neurochemistry. vol 63. issue 6. 1994-12-23. PMID:7964736. |
extracellular 5-hydroxytryptamine (5-ht) in the median raphe and dorsal hippocampus was measured using in vivo microdialysis. |
1994-12-23 |
2023-08-12 |
human |
| F Bosker, A Klompmakers, H Westenber. Extracellular 5-hydroxytryptamine in median raphe nucleus of the conscious rat is decreased by nanomolar concentrations of 8-hydroxy-2-(di-n-propylamino) tetralin and is sensitive to tetrodotoxin. Journal of neurochemistry. vol 63. issue 6. 1994-12-23. PMID:7964736. |
administration of 60 mm k+ through the probe into the median raphe region significantly increased 5-ht output from the median raphe and the right dorsal hippocampus. |
1994-12-23 |
2023-08-12 |
human |
| F Bosker, A Klompmakers, H Westenber. Extracellular 5-hydroxytryptamine in median raphe nucleus of the conscious rat is decreased by nanomolar concentrations of 8-hydroxy-2-(di-n-propylamino) tetralin and is sensitive to tetrodotoxin. Journal of neurochemistry. vol 63. issue 6. 1994-12-23. PMID:7964736. |
local infusion of 10 microm tetrodotoxin into the median raphe region substantially decreased 5-ht in the median raphe and left and right dorsal hippocampus. |
1994-12-23 |
2023-08-12 |
human |
| F Bosker, A Klompmakers, H Westenber. Extracellular 5-hydroxytryptamine in median raphe nucleus of the conscious rat is decreased by nanomolar concentrations of 8-hydroxy-2-(di-n-propylamino) tetralin and is sensitive to tetrodotoxin. Journal of neurochemistry. vol 63. issue 6. 1994-12-23. PMID:7964736. |
systemic administration (0.3 mg/kg s.c.) of 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) decreased the 5-ht levels in the dialysates from both the median raphe region and dorsal hippocampus. |
1994-12-23 |
2023-08-12 |
human |
| F Bosker, A Klompmakers, H Westenber. Extracellular 5-hydroxytryptamine in median raphe nucleus of the conscious rat is decreased by nanomolar concentrations of 8-hydroxy-2-(di-n-propylamino) tetralin and is sensitive to tetrodotoxin. Journal of neurochemistry. vol 63. issue 6. 1994-12-23. PMID:7964736. |
administration of 30 nm 8-oh-dpat through the dialysis probe into the median raphe region decreased 5-ht output from the median raphe and dorsal hippocampus significantly, whereas at concentrations from 60 nm to 10 microm, no significant effects were found in either region. |
1994-12-23 |
2023-08-12 |
human |
| M Wieczorek, A Romaniu. The effects of dorsal and ventral noradrenergic system lesions with DSP-4 on emotional-defensive behavior and regional brain monoamines content in the cat. Behavioural brain research. vol 63. issue 1. 1994-12-20. PMID:7524533. |
following db lesion an increase in emotional-defensive excitation occurred and hplc analysis showed a significant reduction of na concentration in the posterior hypothalamus, midbrain central gray matter and frontal cortex and decreased turnover of 5-ht in all "emotional brain areas" (hypothalamus, midbrain, amygdala, hippocampus) and frontal cortex. |
1994-12-20 |
2023-08-12 |
cat |
| J Malyszko, T Urano, Y Takada, A Takad. Serotonergic systems in brain and blood under stress and tranylcypromine treatment in rats. Brain research bulletin. vol 35. issue 1. 1994-12-20. PMID:7525025. |
we found that animals given tranylcypromine and subjected to water-immersion restraint stress exhibited the greatest rise in 5-ht levels in midbrain, hippocampus, and hypothalamus, together with the lowest 5-hiaa:5-ht ratio relative to controls, whereas in cortex, cerebellum, medulla, and striatum the highest levels of 5-ht together with the lowest ratio of 5-hiaa:5-ht were observed after the administration of tranylcypromine alone. |
1994-12-20 |
2023-08-12 |
rat |
| J W Smythe, W B Rowe, M J Meane. Neonatal handling alters serotonin (5-HT) turnover and 5-HT2 receptor binding in selected brain regions: relationship to the handling effect on glucocorticoid receptor expression. Brain research. Developmental brain research. vol 80. issue 1-2. 1994-12-20. PMID:7525113. |
hypothalamus and amygdala); (2) handling has no long-term effects on hippocampal or frontal cortex 5-ht turnover, and is actually associated with a decrease in 5-ht concentrations; and (3) handling does not alter 5-ht2 receptor density in the hippocampus or frontal cortex in neonates (although there are surprising effects on 5-ht2 receptor density in the frontal cortex of adult animals). |
1994-12-20 |
2023-08-12 |
rat |
| M Frankfurt, C R McKittrick, V N Luin. Short-term fluoxetine treatment alters monoamine levels and turnover in discrete brain nuclei. Brain research. vol 650. issue 1. 1994-12-07. PMID:7525014. |
the major metabolite of 5-ht, 5-hydroxyindoleacetic acid (5-hiaa), was decreased by fluoxetine treatment in the ventromedial hypothalamic nucleus (vmn), the lateral hypothalamic area and the ca1 region of the hippocampus. |
1994-12-07 |
2023-08-12 |
rat |
| L Ballerini, R Corradetti, A Nistri, A M Pugliese, G Stocc. Electrophysiological interactions between 5-hydroxytryptamine and thyrotropin releasing hormone on rat hippocampal CA1 neurons. The European journal of neuroscience. vol 6. issue 6. 1994-12-07. PMID:7952282. |
intracellular recording from ca1 neurons of the rat hippocampal slice preparation was used to examine the possibility of functional interactions between 5-hydroxytryptamine (5-ht) and thyrotropin releasing hormone (trh), which act as cotransmitters in other areas of the central nervous system. |
1994-12-07 |
2023-08-12 |
rat |
| J L Yau, P A Kelly, J Sharkey, J R Seck. Chronic 3,4-methylenedioxymethamphetamine administration decreases glucocorticoid and mineralocorticoid receptor, but increases 5-hydroxytryptamine1C receptor gene expression in the rat hippocampus. Neuroscience. vol 61. issue 1. 1994-11-28. PMID:7969893. |
it is suggested that 5-hydroxytryptamine1c receptors may be involved in mediating the effects of serotonin on hippocampal glucocorticoid receptor and mineralocorticoid receptor expression and perhaps mood. |
1994-11-28 |
2023-08-12 |
rat |
| R N Iyer, J S Sprouse, G K Aghajanian, R H Roth, C W Bradberr. Tryptophan pretreatment augmentation of p-chloroamphetamine-induced serotonin and dopamine release and reduction of long-term neurotoxicity. Biochemical pharmacology. vol 48. issue 7. 1994-11-23. PMID:7945451. |
trp pretreatment (400 mg/kg of the methyl ester) significantly reduced the long-term (1 week) decrease in tissue 5-ht resulting from pca (2 mg/kg, i.p., of the hydrochloride salt) in the prefrontal cortex and striatum, but not in the dorsal hippocampus. |
1994-11-23 |
2023-08-12 |
Not clear |
| S J Murtha, B A Pappa. Neurochemical, histopathological and mnemonic effects of combined lesions of the medial septal and serotonin afferents to the hippocampus. Brain research. vol 651. issue 1-2. 1994-11-16. PMID:7922564. |
neurochemical, histopathological and mnemonic effects of combined lesions of the medial septal and serotonin afferents to the hippocampus. |
1994-11-16 |
2023-08-12 |
rat |
| S J Murtha, B A Pappa. Neurochemical, histopathological and mnemonic effects of combined lesions of the medial septal and serotonin afferents to the hippocampus. Brain research. vol 651. issue 1-2. 1994-11-16. PMID:7922564. |
5,7-dht selectively reduced the concentration of hippocampal serotonin. |
1994-11-16 |
2023-08-12 |
rat |