| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F J Bosker, A A Klompmakers, H G Westenber. Effects of single and repeated oral administration of fluvoxamine on extracellular serotonin in the median raphe nucleus and dorsal hippocampus of the rat. Neuropharmacology. vol 34. issue 5. 1995-11-22. PMID:7566484. |
these results demonstrate that repeated oral treatment with fluvoxamine does not affect extracellular 5-ht in the median raphe and dorsal hippocampus, suggesting that presynaptic functional changes of 5-ht in the brain areas tested are not implicated in the observed delayed onset of action of this ssri in humans. |
1995-11-22 |
2023-08-12 |
rat |
| E C Azmitia, V J Rubinstein, J A Strafaci, J C Rios, P M Whitaker-Azmiti. 5-HT1A agonist and dexamethasone reversal of para-chloroamphetamine induced loss of MAP-2 and synaptophysin immunoreactivity in adult rat brain. Brain research. vol 677. issue 2. 1995-11-14. PMID:7552242. |
two weeks after pca treatment we observed reductions of 5-ht, s100 beta, and map-2 ir in parietal and temporal cortex, temporal pole, hippocampus and hypothalamus. |
1995-11-14 |
2023-08-12 |
rat |
| D Aït Amara, L Segu, S Naïli, M C Buho. Serotonin 1B receptor regulation after dorsal subiculum deafferentation. Brain research bulletin. vol 38. issue 1. 1995-11-14. PMID:7552370. |
we investigated the location of the serotonin 1b receptor (5-ht1b) in the hippocampus with the specific ligand serotonin-o-carboxymethyl-glycyl[125i]tyrosinamide in rat brain sections using in vitro autoradiography. |
1995-11-14 |
2023-08-12 |
rat |
| J Yanai, C G Pic. Neuron transplantation into mice hippocampus alters sensitivity to barbital narcosis. Brain research bulletin. vol 38. issue 1. 1995-11-14. PMID:7552380. |
cholinergic (ach), serotonergic (5-ht), and noradrenergic (ne) innervations were studied in hs strain; whereas balb, which possesses both an unusually high sensitivity to barbital and unique ne innervations in the cortex and hippocampus, was employed in a detailed study of the ne innervations. |
1995-11-14 |
2023-08-12 |
mouse |
| J Yanai, C G Pic. Neuron transplantation into mice hippocampus alters sensitivity to barbital narcosis. Brain research bulletin. vol 38. issue 1. 1995-11-14. PMID:7552380. |
transplantation of embryonic ne cells from the mouse embryo into the hippocampus of adult hs mice increased barbital narcosis by 65% (p < 0.05), whereas transplantation of 5-ht cells decreased barbital narcosis by 54% (p < 0.001). |
1995-11-14 |
2023-08-12 |
mouse |
| J Yanai, C G Pic. Neuron transplantation into mice hippocampus alters sensitivity to barbital narcosis. Brain research bulletin. vol 38. issue 1. 1995-11-14. PMID:7552380. |
the results suggest that (a) enhancement by neural grafting of the ne innervation to the hippocampus accentuates and enhancement of the 5-ht innervations attenuates the sensitivity to barbital narcosis, whereas ach innervations have no effect on the sensitivity to barbital narcosis, and (b) the unusually high sensitivity of balb mice to barbital may not be related to its unique ne innervations. |
1995-11-14 |
2023-08-12 |
mouse |
| S Hjorth, H J Bengtsson, S Milano, J F Lundberg, T Shar. Studies on the role of 5-HT1A autoreceptors and alpha 1-adrenoceptors in the inhibition of 5-HT release--I. BMY7378 and prazosin. Neuropharmacology. vol 34. issue 6. 1995-11-14. PMID:7566497. |
bmy7378 (0.25 mg/kg, s.c.), 8-oh-dpat (0.025 mg/kg, s.c.) and prazosin (0.1-1.0 mg/kg, s.c.) all suppressed ventral hippocampal 5-ht efflux. |
1995-11-14 |
2023-08-12 |
Not clear |
| S I Dworkin, C Co, J E Smit. Rat brain neurotransmitter turnover rates altered during withdrawal from chronic cocaine administration. Brain research. vol 682. issue 1-2. 1995-11-09. PMID:7552301. |
significant increases in tor were also observed which included 5-ht in the preoptic-diagonal band region, da in the hippocampus and na in the pyriform and temporal-auditory cortices, the dentate gyrus and brainstem. |
1995-11-09 |
2023-08-12 |
rat |
| L G Kirby, A R Allen, I Luck. Regional differences in the effects of forced swimming on extracellular levels of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid. Brain research. vol 682. issue 1-2. 1995-11-09. PMID:7552310. |
in the hippocampus and frontal cortex, 5-ht levels were not altered significantly by forced swimming. |
1995-11-09 |
2023-08-12 |
rat |
| N K Popova, A V Kuliko. On the role of brain serotonin in expression of genetic predisposition to catalepsy in animal models. American journal of medical genetics. vol 60. issue 3. 1995-11-07. PMID:7573174. |
the activity of the rate-limiting enzyme of serotonin biosynthesis, tryptophan hydroxylase, in the striatum but not in the hippocampus and midbrain of rats bred for predisposition to catalepsy was higher than in nonselected rats. |
1995-11-07 |
2023-08-12 |
mouse |
| C Yokoyama, H Okamura, Y Ibat. Dopamine D2-like receptors labeled by [3H]YM-09151-2 in the rat hippocampus: characterization and autoradiographic distribution. Brain research. vol 681. issue 1-2. 1995-11-06. PMID:7552274. |
the hippocampal [3h]ym-09151-2 binding did not represent serotonergic receptors (5-ht1a and 5-ht2) and sigma receptor, since ki values of ketanserine, serotonin, 8-oh-dpat and dtg were much lower than d2-like receptor antagonists. |
1995-11-06 |
2023-08-12 |
rat |
| R Numazawa, M Yoshioka, M Matsumoto, H Togashi, O Kemmotsu, H Sait. Pharmacological characterization of alpha 2-adrenoceptor regulated serotonin release in the rat hippocampus. Neuroscience letters. vol 192. issue 3. 1995-11-06. PMID:7566640. |
pharmacological characterization of alpha 2-adrenoceptor regulated serotonin release in the rat hippocampus. |
1995-11-06 |
2023-08-12 |
rat |
| R Numazawa, M Yoshioka, M Matsumoto, H Togashi, O Kemmotsu, H Sait. Pharmacological characterization of alpha 2-adrenoceptor regulated serotonin release in the rat hippocampus. Neuroscience letters. vol 192. issue 3. 1995-11-06. PMID:7566640. |
the purpose of the present study was to confirm the functional regulation by alpha 2-adrenoceptors of the release of serotonin (5-ht) from the rat hippocampus in vivo. |
1995-11-06 |
2023-08-12 |
rat |
| R Numazawa, M Yoshioka, M Matsumoto, H Togashi, O Kemmotsu, H Sait. Pharmacological characterization of alpha 2-adrenoceptor regulated serotonin release in the rat hippocampus. Neuroscience letters. vol 192. issue 3. 1995-11-06. PMID:7566640. |
extracellular 5-ht in the hippocampus was reduced by tetrodotoxin (10 microm) co-perfusion, but increased by perfusion of a selective 5-ht re-uptake inhibitor, fluoxetine (10 microm). |
1995-11-06 |
2023-08-12 |
rat |
| R Numazawa, M Yoshioka, M Matsumoto, H Togashi, O Kemmotsu, H Sait. Pharmacological characterization of alpha 2-adrenoceptor regulated serotonin release in the rat hippocampus. Neuroscience letters. vol 192. issue 3. 1995-11-06. PMID:7566640. |
these findings suggest that 5-ht release is functionally modulated via alpha 2-adrenoceptors located on the serotonergic nerve terminals in the rat hippocampus and furthermore, the possibility that the inhibitory of alpha 2-adrenoceptors is linked to g-proteins which are substrates of ptx. |
1995-11-06 |
2023-08-12 |
rat |
| H Andersson, J Luthman, E Lindqvist, L Olso. Time-course of trimethyltin effects on the monoaminergic systems of the rat brain. Neurotoxicology. vol 16. issue 2. 1995-10-30. PMID:7566680. |
in addition, a reduced density of 5-ht immunoreactive fibers was seen in hippocampus and cortex. |
1995-10-30 |
2023-08-12 |
rat |
| H Andersson, J Luthman, E Lindqvist, L Olso. Time-course of trimethyltin effects on the monoaminergic systems of the rat brain. Neurotoxicology. vol 16. issue 2. 1995-10-30. PMID:7566680. |
twelve weeks after tmt treatment, 5-ht and na levels were increased in hippocampus, and 5-ht levels in striatum. |
1995-10-30 |
2023-08-12 |
rat |
| G Bollweg, C Balaban, H J Cox, B Berra, S B Sparbe. Potential efficacy and toxicity of GM1 ganglioside against trimethyltin-induced brain lesions in rats: comparison with protracted food restriction. Neurotoxicology. vol 16. issue 2. 1995-10-30. PMID:7566684. |
gm1 also reduced hippocampal serotonin concentration, another "lesion-like" change. |
1995-10-30 |
2023-08-12 |
rat |
| S V Kala, A L Jadha. Region-specific alterations in dopamine and serotonin metabolism in brains of rats exposed to low levels of lead. Neurotoxicology. vol 16. issue 2. 1995-10-30. PMID:7566689. |
frontal cortex (fc), nucleus accumbens (na), striatum (st), hypothalamus (hy), hippocampus (hip) and brainstem (bs) regions were analyzed for dopamine (da), serotonin (5ht) and their metabolites. |
1995-10-30 |
2023-08-12 |
rat |
| J J Alexander, P Banerjee, G Dawson, J H Tonsgar. Hyperammonemia increases serotonin 1A receptor expression in both rat hippocampus and a transfected hippocampal cell line, HN2-5. Journal of neuroscience research. vol 41. issue 1. 1995-10-17. PMID:7674372. |
hyperammonemia increases serotonin 1a receptor expression in both rat hippocampus and a transfected hippocampal cell line, hn2-5. |
1995-10-17 |
2023-08-12 |
rat |