| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Yamazaki, Y Kiuchi, M Inagaki, M Matsumoto, C Yokomizo, N Nakachi, T Uchikawa, K Oguch. [Increase in extracellular levels of serotonin and amino acids in the rat brain following cyanide-induced energy failure]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 15. issue 4. 1995-12-14. PMID:7584727. |
nacn perfusion induced a transient 3.9-fold increase in 5-ht levels in the hippocampal dialysate. |
1995-12-14 |
2023-08-12 |
rat |
| R Tao, S B Auerbac. Involvement of the dorsal raphe but not median raphe nucleus in morphine-induced increases in serotonin release in the rat forebrain. Neuroscience. vol 68. issue 2. 1995-12-12. PMID:7477965. |
after systemic morphine (10 mg/kg, s.c.), increases in extracellular serotonin were observed in the nucleus accumbens, amygdala, frontal cortex, striatum, thalamus, hypothalamus and ventral hippocampus. |
1995-12-12 |
2023-08-12 |
rat |
| R Tao, S B Auerbac. Involvement of the dorsal raphe but not median raphe nucleus in morphine-induced increases in serotonin release in the rat forebrain. Neuroscience. vol 68. issue 2. 1995-12-12. PMID:7477965. |
in contrast, serotonin was not significantly increased in the medial septal nucleus and dorsal hippocampus. |
1995-12-12 |
2023-08-12 |
rat |
| S Novotney, M T Low. Short-term and long-term effects of p-chloroamphetamine on hippocampal serotonin and corticosteroid receptor levels. Brain research. vol 684. issue 1. 1995-12-12. PMID:7583200. |
short-term and long-term effects of p-chloroamphetamine on hippocampal serotonin and corticosteroid receptor levels. |
1995-12-12 |
2023-08-12 |
rat |
| S Novotney, M T Low. Short-term and long-term effects of p-chloroamphetamine on hippocampal serotonin and corticosteroid receptor levels. Brain research. vol 684. issue 1. 1995-12-12. PMID:7583200. |
hippocampal corticosteroid receptors are regulated by corticosterone as well as by neurotransmitters, such as serotonin (5-ht). |
1995-12-12 |
2023-08-12 |
rat |
| S Novotney, M T Low. Short-term and long-term effects of p-chloroamphetamine on hippocampal serotonin and corticosteroid receptor levels. Brain research. vol 684. issue 1. 1995-12-12. PMID:7583200. |
studies have demonstrated that long-term changes in 5-ht levels are associated with alterations in hippocampal glucocorticoid receptor (gr) and mineralocorticoid receptor (mr) number. |
1995-12-12 |
2023-08-12 |
rat |
| S Novotney, M T Low. Short-term and long-term effects of p-chloroamphetamine on hippocampal serotonin and corticosteroid receptor levels. Brain research. vol 684. issue 1. 1995-12-12. PMID:7583200. |
however, the effect of short-term manipulations of 5-ht levels on hippocampal corticosteroid receptor levels has not been thoroughly investigated. |
1995-12-12 |
2023-08-12 |
rat |
| S Novotney, M T Low. Short-term and long-term effects of p-chloroamphetamine on hippocampal serotonin and corticosteroid receptor levels. Brain research. vol 684. issue 1. 1995-12-12. PMID:7583200. |
the present set of studies examined the effect of para-chloroamphetamine (pca) administration on both short-term and long-term regulation of hippocampal 5-ht and corticosteroid receptor levels. |
1995-12-12 |
2023-08-12 |
rat |
| S Novotney, M T Low. Short-term and long-term effects of p-chloroamphetamine on hippocampal serotonin and corticosteroid receptor levels. Brain research. vol 684. issue 1. 1995-12-12. PMID:7583200. |
pca produced a large decrease in hippocampal 5-ht (-79%) and 5-hydroxyindoleacetic acid (5-hiaa) (-40%) concentrations. |
1995-12-12 |
2023-08-12 |
rat |
| S Novotney, M T Low. Short-term and long-term effects of p-chloroamphetamine on hippocampal serotonin and corticosteroid receptor levels. Brain research. vol 684. issue 1. 1995-12-12. PMID:7583200. |
in a final experiment, the long-term (7 days) effect of pca administration on hippocampal 5-ht and corticosteroid receptor levels was examined. |
1995-12-12 |
2023-08-12 |
rat |
| S Novotney, M T Low. Short-term and long-term effects of p-chloroamphetamine on hippocampal serotonin and corticosteroid receptor levels. Brain research. vol 684. issue 1. 1995-12-12. PMID:7583200. |
pca produced an 87% decrease in hippocampal 5-ht and 5-hiaa levels, but did not alter hippocampal gr or mr levels. |
1995-12-12 |
2023-08-12 |
rat |
| J W Li, M Watanabe, Y Fujisawa, T Shibuy. Relation between age-related changes in hyper-emotionality and serotonergic neuronal activities in the rat limbic system. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 15. issue 3. 1995-12-07. PMID:7584716. |
in the neurochemical studies, the concentrations of 5-ht and 5-hiaa in the limbic system (e.g., hippocampus, amygdala and septal area) of aged rats were much higher than those of young rats (p < 0.001) under normal conditions. |
1995-12-07 |
2023-08-12 |
rat |
| M I Colado, J L Williams, A R Gree. The hyperthermic and neurotoxic effects of 'Ecstasy' (MDMA) and 3,4 methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor metabolizer phenotype. British journal of pharmacology. vol 115. issue 7. 1995-12-01. PMID:7582557. |
there was a substantial loss in the concentration of 5-ht and 5-hydroxyindoleacetic acid (5-hia) in cortex and hippocampus. |
1995-12-01 |
2023-08-12 |
human |
| M I Colado, J L Williams, A R Gree. The hyperthermic and neurotoxic effects of 'Ecstasy' (MDMA) and 3,4 methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor metabolizer phenotype. British journal of pharmacology. vol 115. issue 7. 1995-12-01. PMID:7582557. |
produced a major (approximately 40%) loss of 5-ht content of cortex and hippocampus 7 days later. |
1995-12-01 |
2023-08-12 |
human |
| M Popoli, C Vocaturo, J Perez, E Smeraldi, G Racagn. Presynaptic Ca2+/calmodulin-dependent protein kinase II: autophosphorylation and activity increase in the hippocampus after long-term blockade of serotonin reuptake. Molecular pharmacology. vol 48. issue 4. 1995-11-29. PMID:7476887. |
presynaptic ca2+/calmodulin-dependent protein kinase ii: autophosphorylation and activity increase in the hippocampus after long-term blockade of serotonin reuptake. |
1995-11-29 |
2023-08-12 |
Not clear |
| M Popoli, C Vocaturo, J Perez, E Smeraldi, G Racagn. Presynaptic Ca2+/calmodulin-dependent protein kinase II: autophosphorylation and activity increase in the hippocampus after long-term blockade of serotonin reuptake. Molecular pharmacology. vol 48. issue 4. 1995-11-29. PMID:7476887. |
long-term treatment with two selective serotonin reuptake inhibitors (paroxetine and fluvoxamine) and with a nonselective reuptake inhibitor (venlafaxine) induces a large increase of kinase autophosphorylation in synaptic vesicles and synaptic cytosol in the hippocampus but not in synaptosomal membranes. |
1995-11-29 |
2023-08-12 |
Not clear |
| F J Bosker, A A Klompmakers, H G Westenber. Effects of single and repeated oral administration of fluvoxamine on extracellular serotonin in the median raphe nucleus and dorsal hippocampus of the rat. Neuropharmacology. vol 34. issue 5. 1995-11-22. PMID:7566484. |
effects of single and repeated oral administration of fluvoxamine on extracellular serotonin in the median raphe nucleus and dorsal hippocampus of the rat. |
1995-11-22 |
2023-08-12 |
rat |
| F J Bosker, A A Klompmakers, H G Westenber. Effects of single and repeated oral administration of fluvoxamine on extracellular serotonin in the median raphe nucleus and dorsal hippocampus of the rat. Neuropharmacology. vol 34. issue 5. 1995-11-22. PMID:7566484. |
to examine the effects of repeated administration of ssris on serotonin neurotransmission, we investigated the effects of acute and chronic administration of the ssri fluvoxamine on the extracellular levels of 5-ht in the median raphe nucleus and dorsal hippocampus of conscious rats by means of brain microdialysis. |
1995-11-22 |
2023-08-12 |
rat |
| F J Bosker, A A Klompmakers, H G Westenber. Effects of single and repeated oral administration of fluvoxamine on extracellular serotonin in the median raphe nucleus and dorsal hippocampus of the rat. Neuropharmacology. vol 34. issue 5. 1995-11-22. PMID:7566484. |
a single oral dose of fluvoxamine (30 mg/kg) augmented extracellular 5-ht in the median raphe and dorsal hippocampus to 270 and 191% of baseline level, respectively. |
1995-11-22 |
2023-08-12 |
rat |
| F J Bosker, A A Klompmakers, H G Westenber. Effects of single and repeated oral administration of fluvoxamine on extracellular serotonin in the median raphe nucleus and dorsal hippocampus of the rat. Neuropharmacology. vol 34. issue 5. 1995-11-22. PMID:7566484. |
moreover, the increase in extracellular 5-ht in the median raphe nucleus and dorsal hippocampus after an oral dose of fluvoxamine (30 mg/kg) in rats chronically treated with fluvoxamine was not different from rats treated with vehicle. |
1995-11-22 |
2023-08-12 |
rat |