| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Lew, K E Sabol, C Chou, G L Vosmer, J Richards, L S Seide. Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part II: Radioligand binding and autoradiography studies. The Journal of pharmacology and experimental therapeutics. vol 276. issue 2. 1996-07-03. PMID:8632359. |
by 16 wk, a partial recovery in the number of 5-ht uptake sites was observed in both tissues; however, only a full recovery of serotonin uptake sites was observed in hippocampus at the end of 52 wk. |
1996-07-03 |
2023-08-12 |
rat |
| R Lew, K E Sabol, C Chou, G L Vosmer, J Richards, L S Seide. Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part II: Radioligand binding and autoradiography studies. The Journal of pharmacology and experimental therapeutics. vol 276. issue 2. 1996-07-03. PMID:8632359. |
in addition, recovery of 5-ht uptake site in hippocampus also followed a rostral-caudal gradient. |
1996-07-03 |
2023-08-12 |
rat |
| R Lew, K E Sabol, C Chou, G L Vosmer, J Richards, L S Seide. Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part II: Radioligand binding and autoradiography studies. The Journal of pharmacology and experimental therapeutics. vol 276. issue 2. 1996-07-03. PMID:8632359. |
in conclusion, our study is consistent with previous studies describing the selective neurotoxicity of mdma for serotonin neurons and presents evidence showing the rate of recovery of 5-ht uptake sites varies according to region and that recovery of 5-ht uptake sites in neocortex and hippocampus follows a rostral-caudal gradient. |
1996-07-03 |
2023-08-12 |
rat |
| F J Bosker, T Y de Winter, A A Klompmakers, H G Westenber. Flesinoxan dose-dependently reduces extracellular 5-hydroxytryptamine (5-HT) in rat median raphe and dorsal hippocampus through activation of 5-HT1A receptors. Journal of neurochemistry. vol 66. issue 6. 1996-07-01. PMID:8632181. |
flesinoxan dose-dependently reduces extracellular 5-hydroxytryptamine (5-ht) in rat median raphe and dorsal hippocampus through activation of 5-ht1a receptors. |
1996-07-01 |
2023-08-12 |
rat |
| F J Bosker, T Y de Winter, A A Klompmakers, H G Westenber. Flesinoxan dose-dependently reduces extracellular 5-hydroxytryptamine (5-HT) in rat median raphe and dorsal hippocampus through activation of 5-HT1A receptors. Journal of neurochemistry. vol 66. issue 6. 1996-07-01. PMID:8632181. |
the effects of systemic administration of the serotonin (5-hydroxytryptamine) 5-ht1a receptor agonists flesinoxan and 8-hydroxy-2-(di-n-propylamino)tetralin on extracellular 5-ht were measured using microdialysis probes in both median raphe nucleus and dorsal hippocampus. |
1996-07-01 |
2023-08-12 |
rat |
| R J Thielen, N B Fangon, A Fraze. 4-(2'-Methoxyphenyl)-1-[2'-[N-(2"-pyridinyl)-p-iodobenzamido]ethyl] piperazine and 4-(2'-methoxyphenyl)-1-[2'-[N-(2"-pyridinyl)-p- fluorobenzamido]ethyl]piperazine, two new antagonists at pre- and postsynaptic serotonin-1A receptors. The Journal of pharmacology and experimental therapeutics. vol 277. issue 2. 1996-06-27. PMID:8627543. |
p-mppi and p-mppf were able to antagonize the 8-oh-dpat-(0.5 mg/kg) induced reduction in the 5-hiaa/5-ht ratio, a measure of 5-ht turnover in the hippocampus or striatum. |
1996-06-27 |
2023-08-12 |
rat |
| K Kasamo, P Blier, C De Montign. Blockade of the serotonin and norepinephrine uptake processes by duloxetine: in vitro and in vivo studies in the rat brain. The Journal of pharmacology and experimental therapeutics. vol 277. issue 1. 1996-06-06. PMID:8613930. |
in in vitro uptake experiments, duloxetine inhibited [3h]5-hydroxytryptamine (5-ht) and [3h]norepinephrine (ne) uptake in hippocampus slices of control rats with ic50 values of 28 and 46 nm, respectively. |
1996-06-06 |
2023-08-12 |
rat |
| K Kasamo, P Blier, C De Montign. Blockade of the serotonin and norepinephrine uptake processes by duloxetine: in vitro and in vivo studies in the rat brain. The Journal of pharmacology and experimental therapeutics. vol 277. issue 1. 1996-06-06. PMID:8613930. |
the uptake of both[3h]5-ht and [3h]ne was equipotently inhibited in hippocampus slices prepared from rats treated for 2 days with different doses of duloxetine (5, 10, 15 and 20 mg/kg/day s.c.). |
1996-06-06 |
2023-08-12 |
rat |
| K Kasamo, P Blier, C De Montign. Blockade of the serotonin and norepinephrine uptake processes by duloxetine: in vitro and in vivo studies in the rat brain. The Journal of pharmacology and experimental therapeutics. vol 277. issue 1. 1996-06-06. PMID:8613930. |
in in vivo electrophysiological experiments in the hippocampus, the effects of duloxetine on the suppression of ca3 pyramidal neuronal firing activity by microiontophoretically applied 5-ht and ne were examined with two modes of administration. |
1996-06-06 |
2023-08-12 |
rat |
| I Malagié, A C Trillat, C Jacquot, A M Gardie. Effects of acute fluoxetine on extracellular serotonin levels in the raphe: an in vivo microdialysis study. European journal of pharmacology. vol 286. issue 2. 1996-05-22. PMID:8605960. |
increased extracellular levels of serotonin (5-hydroxytryptamine, 5-ht) in the frontal cortex, ventral hippocampus and raphe nuclei as measured by in vivo microdialysis in anaesthetized rats. |
1996-05-22 |
2023-08-12 |
rat |
| I Malagié, A C Trillat, C Jacquot, A M Gardie. Effects of acute fluoxetine on extracellular serotonin levels in the raphe: an in vivo microdialysis study. European journal of pharmacology. vol 286. issue 2. 1996-05-22. PMID:8605960. |
the order of changes in extracellular 5-ht was raphe nuclei > ventral hippocampus > frontal cortex. |
1996-05-22 |
2023-08-12 |
rat |
| R A Keith, T J Mangano, R A Lampe, P A DeFeo, M J Hyde, B A Donzant. Comparative actions of synthetic omega-grammotoxin SIA and synthetic omega-Aga-IVA on neuronal calcium entry and evoked release of neurotransmitters in vitro and in vivo. Neuropharmacology. vol 34. issue 11. 1996-05-20. PMID:8606798. |
in urethane anesthetized rats, omega-cgtx gvia caused a partial inhibition, whereas omega-gstx sia caused a concentration-dependent and complete inhibition, of basal serotonin release in the hippocampus. |
1996-05-20 |
2023-08-12 |
rat |
| G Piñeyro, C de Montigny, P Blie. 5-HT1D receptors regulate 5-HT release in the rat raphe nuclei. In vivo voltammetry and in vitro superfusion studies. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 13. issue 3. 1996-05-15. PMID:8602897. |
the selective 5-ht1b agonist cp 93129 (10-10,000 nm), had no effect in raphe slices, but it dose dependently inhibited [3h]5-ht release from hippocampal slices where autoreceptors are of the 5-ht1b subtype. |
1996-05-15 |
2023-08-12 |
rat |
| A Castaño, A Ayala, J A Rodriguez-Gomez, C P de la Cruz, E Revilla, J Cano, A Machad. Increase in dopamine turnover and tyrosine hydroxylase enzyme in hippocampus of rats fed on low selenium diet. Journal of neuroscience research. vol 42. issue 5. 1996-04-30. PMID:8600301. |
we have studied the turnover of dopamine, noradrenaline, and serotonin and their metabolites in hippocampus of adult female rats that were fed control or selenium-deficient diets during 15 days. |
1996-04-30 |
2023-08-12 |
rat |
| Y Odagaki, K Fux. Functional coupling between A1 adenosine receptors and G-proteins in rat hippocampal membranes assessed by high-affinity GTPase activity. British journal of pharmacology. vol 116. issue 6. 1996-04-04. PMID:8590991. |
the activating effects on high-affinity gtpase of r-pia (via a1 adenosine receptors) and of 5-ht (via 5-ht1a receptors) were completely additive, indicating that a1 adenosine and 5-ht1a receptors were coupled to distinct pools of g-proteins in hippocampus. |
1996-04-04 |
2023-08-12 |
rat |
| C Stenfors, P Bjellerup, A A Mathé, E Theodorsso. Concurrent analysis of neuropeptides and biogenic amines in brain tissue of rats treated with electroconvulsive stimuli. Brain research. vol 698. issue 1-2. 1996-03-20. PMID:8581501. |
new findings were a decrease in noradrenaline concentrations in the frontal and occipital cortex and hippocampus, an increase in dopamine concentrations in the frontal and occipital cortex and no serotonin change. |
1996-03-20 |
2023-08-12 |
rat |
| A Kulikov, N Castanon, P Mormède, F Chaoulof. Cerebral tryptophan hydroxylase activity, and 5-HT1A receptor, 5-HT2A receptor, and 5-HT transporter binding in grouped and isolated Roman RHA and RLA rats: relationships with behaviours in two models of anxiety. Psychopharmacology. vol 121. issue 3. 1996-03-19. PMID:8584622. |
neither midbrain and hippocampal [3h]8-hydroxy-2-(di-n-propylamino)-tetrlin binding at 5-ht1a receptors, nor midbrain [3h] citalopram binding at the 5-ht transporter was different between grouped/isolated rha/rla rats. |
1996-03-19 |
2023-08-12 |
rat |
| T Tadano, A Yonezawa, K Oyama, K Kisara, Y Arai, M Togashi, H Kinemuch. Effects of transient global ischemia and a monoamine oxidase inhibitor ifenprodil on rat brain monoamine metabolism. Progress in brain research. vol 106. 1996-03-15. PMID:8584652. |
among the three most ischaemically vulnerable brain regions (striatum, hippocampus and cortex), striatal da, dopac, hva, 5-ht and 5-hiaa levels were the most markedly increased. |
1996-03-15 |
2023-08-12 |
rat |
| M Frankfurt, C R McKittrick, B S McEwen, V N Luin. Tianeptine treatment induces regionally specific changes in monoamines. Brain research. vol 696. issue 1-2. 1996-03-14. PMID:8574656. |
5-ht levels were increased by short-term tianeptine in the ca3 region of hippocampus, and 5-hydroxyindoleacetic acid (5-hiaa) was increased in the ventromedial nucleus of hypothalamus, while 5-ht turnover was decreased in preoptic area (poa). |
1996-03-14 |
2023-08-12 |
rat |
| R Invernizzi, M Bramante, R Samani. Extracellular concentrations of serotonin in the dorsal hippocampus after acute and chronic treatment with citalopram. Brain research. vol 696. issue 1-2. 1996-03-14. PMID:8574685. |
extracellular concentrations of serotonin in the dorsal hippocampus after acute and chronic treatment with citalopram. |
1996-03-14 |
2023-08-12 |
rat |