| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Ge, N M Barne. 5-HT4 receptor-mediated modulation of 5-HT release in the rat hippocampus in vivo. British journal of pharmacology. vol 117. issue 7. 1996-10-10. PMID:8730742. |
5-ht4 receptor-mediated modulation of 5-ht release in the rat hippocampus in vivo. |
1996-10-10 |
2023-08-12 |
rat |
| J Ge, N M Barne. 5-HT4 receptor-mediated modulation of 5-HT release in the rat hippocampus in vivo. British journal of pharmacology. vol 117. issue 7. 1996-10-10. PMID:8730742. |
in the present study, the ability of the 5-hydroxytryptamine, receptor (5-ht4 receptor) to modulate the release of 5-ht in the hippocampus of freely-moving rats was investigated by the in vivo microdialysis technique. |
1996-10-10 |
2023-08-12 |
rat |
| J Ge, N M Barne. 5-HT4 receptor-mediated modulation of 5-HT release in the rat hippocampus in vivo. British journal of pharmacology. vol 117. issue 7. 1996-10-10. PMID:8730742. |
the 5-ht4 receptor agonist, renzapride (1.0-100 microm, administered via the microdialysis probe) increased extracellular hippocampal levels of 5-ht in concentration-dependent manner (approximately 200% maximal increase). |
1996-10-10 |
2023-08-12 |
rat |
| J Ge, N M Barne. 5-HT4 receptor-mediated modulation of 5-HT release in the rat hippocampus in vivo. British journal of pharmacology. vol 117. issue 7. 1996-10-10. PMID:8730742. |
furthermore, another 5-ht4 receptor agonist 5-methoxytryptamine (5-meot; 10 microm, administered via the microdialysis probe, in the presence of the non-5-ht4 5-ht receptor antagonists pindolol (10 microm) and methysergide (10 microm)) maximally elevated extracellular levels of 5-ht by approximately 450% in the rat hippocampus. |
1996-10-10 |
2023-08-12 |
rat |
| J Ge, N M Barne. 5-HT4 receptor-mediated modulation of 5-HT release in the rat hippocampus in vivo. British journal of pharmacology. vol 117. issue 7. 1996-10-10. PMID:8730742. |
gr113808 (100 nm, administered via the microdialysis probe) administered alone, however, reduced extracellular hippocampal 5-ht levels by some 60%. |
1996-10-10 |
2023-08-12 |
rat |
| J Ge, N M Barne. 5-HT4 receptor-mediated modulation of 5-HT release in the rat hippocampus in vivo. British journal of pharmacology. vol 117. issue 7. 1996-10-10. PMID:8730742. |
systemic administration of the 5-ht1a receptor agonist, 8-oh-dpat (0.1 mg kg-1, s.c.) reduced extracellular levels of 5-ht in the rat hippocampus by approximately 40%. |
1996-10-10 |
2023-08-12 |
rat |
| J Ge, N M Barne. 5-HT4 receptor-mediated modulation of 5-HT release in the rat hippocampus in vivo. British journal of pharmacology. vol 117. issue 7. 1996-10-10. PMID:8730742. |
prior administration of 8-oh-dpat (0.1 mg kg-1, s.c.), with an associated reduction of extracellular hippocampal 5-ht levels by approximately 40-50%, however, failed to prevent a subsequent elevation of extracellular levels of 5-ht induced by renzapride (100 microm, administered via the microdialysis probe). |
1996-10-10 |
2023-08-12 |
rat |
| J Ge, N M Barne. 5-HT4 receptor-mediated modulation of 5-HT release in the rat hippocampus in vivo. British journal of pharmacology. vol 117. issue 7. 1996-10-10. PMID:8730742. |
increased extracellular levels of 5-ht in the hippocampus in a dose-dependent manner. |
1996-10-10 |
2023-08-12 |
rat |
| J Ge, N M Barne. 5-HT4 receptor-mediated modulation of 5-HT release in the rat hippocampus in vivo. British journal of pharmacology. vol 117. issue 7. 1996-10-10. PMID:8730742. |
caused a dose-dependent reduction in extracellular levels of 5-ht in the hippocampus (maximally approximately 80% reduction). |
1996-10-10 |
2023-08-12 |
rat |
| J Ge, N M Barne. 5-HT4 receptor-mediated modulation of 5-HT release in the rat hippocampus in vivo. British journal of pharmacology. vol 117. issue 7. 1996-10-10. PMID:8730742. |
in conclusion, the present study provides evidence that activation of the 5-ht4 receptor facilitates 5-ht release in the rat hippocampus in vivo. |
1996-10-10 |
2023-08-12 |
rat |
| A J Bugajski, Z Chłap, J Bugajski, J Boryc. Effect of compound 48/80 on mast cells and biogenic amine levels in brain structures and on corticosterone secretion. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 46. issue 4. 1996-10-09. PMID:8770794. |
the effect of compound 48/80, given intracerebroventricularly, on mast cells (mc) and histamine, serotonin and noradrenaline levels in the hypothalamus, thalamus and hippocampus as well as on corticosterone secretion was investigated in rats. |
1996-10-09 |
2023-08-12 |
rat |
| J Pascual, C Del Arco, T Romón, E Del Olmo, A Pazo. [3H]Sumatriptan binding sites in human brain: regional-dependent labelling of 5-HT1D and 5-HT1F receptors. European journal of pharmacology. vol 295. issue 2-3. 1996-09-26. PMID:8720594. |
although the binding inhibited by 5-ct in some regions such as globus pallidus and substantia nigra was equivalent to that obtained with 5-ht, in cortical areas, such as frontal cortex and hippocampus, a substantial level of binding insensitive to 5-ct was seen. |
1996-09-26 |
2023-08-12 |
human |
| R Manhães de Castro, F Bolaños-Jiménez, L Seguin, H Sarhan, K Drieu, G Fillio. Sub-chronic cold stress reduces 5-HT1A receptor responsiveness in the old but not in the young rat. Neuroscience letters. vol 203. issue 1. 1996-09-26. PMID:8742037. |
the inhibitory effect of the prototypical 5-hydroxytryptamine (5-ht)1a receptor agonist 8-hydroxy-2-(di-n-propyl amino)tetraline (8-oh-dpat) on forskolin-stimulated adenylyl cyclase activity, has been examined as an index of the functional activity of 5-ht1a receptors in the hippocampus of young (3 months) and old (18 months) rats exposed during 24 h or 5 days to cold. |
1996-09-26 |
2023-08-12 |
rat |
| W J McBride, B Bodart, L Lumeng, T K L. Association between low contents of dopamine and serotonin in the nucleus accumbens and high alcohol preference. Alcoholism, clinical and experimental research. vol 19. issue 6. 1996-09-26. PMID:8749804. |
the contents of dopamine (da), 3,4-dihydroxyphenylacetic acid (dopac), homovanillic acid (hva), serotonin (5-ht), and 5-hydroxyindoleacetic acid (5-hiaa) were determined in the nucleus accumbens (acb), frontal cortex (fr), anterior striatum (ast), and hippocampus (hip) of adult male rats from the f2 generation of p x np intercrosses. |
1996-09-26 |
2023-08-12 |
rat |
| K B Kumar, K Nalini, K S Karant. Effects of p-chlorophenylalanine-induced depletion of brain serotonin on retrieval of appetitive and aversive memories. Indian journal of experimental biology. vol 33. issue 11. 1996-09-25. PMID:8786157. |
while lower doses of p-cpa selectively reduced serotonin levels in striatum and anterior cortex, higher doses reduced both serotonin and norepinephrine levels in hippocampus in a dose-dependent fashion. |
1996-09-25 |
2023-08-12 |
rat |
| J E Malberg, K E Sabol, L S Seide. Co-administration of MDMA with drugs that protect against MDMA neurotoxicity produces different effects on body temperature in the rat. The Journal of pharmacology and experimental therapeutics. vol 278. issue 1. 1996-09-23. PMID:8764359. |
mdma produced significant (p < .05) decreases in 5-ht and 5-hydroxindole acetic acid levels in the frontal cortex, somatosensory cortex, striatum and hippocampus, and pretreatment with ket or ampt prevented these depletions. |
1996-09-23 |
2023-08-12 |
rat |
| J E Malberg, K E Sabol, L S Seide. Co-administration of MDMA with drugs that protect against MDMA neurotoxicity produces different effects on body temperature in the rat. The Journal of pharmacology and experimental therapeutics. vol 278. issue 1. 1996-09-23. PMID:8764359. |
the fluox pretreatment protected against mdma-induced 5-ht and 5-hydroxindole acetic acid depletions in the frontal cortex, somatosensory cortex, striatum and hippocampus. |
1996-09-23 |
2023-08-12 |
rat |
| M Bija. Monoamine modulation of the synaptic inhibition in the hippocampus. Acta neurobiologiae experimentalis. vol 56. issue 1. 1996-09-23. PMID:8787199. |
in the hippocampal dentate gyrus, norepinephrine and serotonin (5-ht) have multiple direct and indirect actions on the presumed inhibitory hilar neurones. |
1996-09-23 |
2023-08-12 |
Not clear |
| M Rattray, S Baldessari, M Gobbi, T Mennini, R Samanin, C Bendott. p-Chlorphenylalanine changes serotonin transporter mRNA levels and expression of the gene product. Journal of neurochemistry. vol 67. issue 2. 1996-09-19. PMID:8764569. |
pcpa administration produced no change in the [3h]citalopram binding and synaptosomal [3h]5-ht uptake in terminal regions at 2 and 7 days after treatment but significantly reduced both these parameters by approximately 20% in the hippocampus and in cerebral cortex 14 days after pcpa administration. |
1996-09-19 |
2023-08-12 |
Not clear |
| C S Tung, C C Lu, Y P Liu, C J Tseng, T H Yi. Schedule-induced polydipsia increased both mesotelencephalic-dopaminergic and pontine-noradrenergic activities in the rat brain. The Chinese journal of physiology. vol 38. issue 2. 1996-09-05. PMID:8697899. |
conversely, both ne and 5-ht metabolism in the hippocampus and the cortex were decreased. |
1996-09-05 |
2023-08-12 |
rat |