| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P J Fletche. Effects of combined or separate 5,7-dihydroxytryptamine lesions of the dorsal and median raphe nuclei on responding maintained by a DRL 20s schedule of food reinforcement. Brain research. vol 675. issue 1-2. 1995-08-03. PMID:7540930. |
dorsal raphe 5,7-dht lesions, that depleted striatal 5-ht by 56%, and hippocampal 5-ht by 30%, had no effect on behaviour. |
1995-08-03 |
2023-08-12 |
rat |
| R Jackisch, B Neufang, G Hertting, H Jeltsch, C Kelche, B Will, J C Casse. Sympathetic sprouting: time course of changes of noradrenergic, cholinergic, and serotonergic markers in the denervated rat hippocampus. Journal of neurochemistry. vol 65. issue 1. 1995-07-26. PMID:7540665. |
at various postsurgical delays (1, 2, 8, 24, and 40 weeks), the activity of choline acetyltransferase, the high-affinity synaptosomal uptake of choline and noradrenaline, and the concentrations of noradrenaline, serotonin, and 5-hydroxyindoleacetic acid were measured in a dorsal, an intermediate, and a ventral part of the hippocampus. |
1995-07-26 |
2023-08-12 |
rat |
| K Tsuiki, Y L Yamamoto, M Diksi. Effect of acute fluoxetine treatment on the brain serotonin synthesis as measured by the alpha-methyl-L-tryptophan autoradiographic method. Journal of neurochemistry. vol 65. issue 1. 1995-07-26. PMID:7790867. |
the greatest increase (given as a percentage of rates in control animals) in the rate of serotonin synthesis was observed in the substantia nigra compacta (344%), hippocampus-ca3 (337%), dorsal hippocampus (283%), and caudate-putamen (232%). |
1995-07-26 |
2023-08-12 |
rat |
| A Gobert, F Lejeune, J M Rivet, V Audinot, A Newman-Tancredi, M J Milla. Modulation of the activity of central serotoninergic neurons by novel serotonin1A receptor agonists and antagonists: a comparison to adrenergic and dopaminergic neurons in rats. The Journal of pharmacology and experimental therapeutics. vol 273. issue 3. 1995-07-21. PMID:7791073. |
with the exception of (-)-tertatolol, which behaved as a weak agonist, a very similar pattern of inhibition of 5-ht turnover was seen in the striatum (innervated by the drn), the hippocampus and the hypothalamus (drn and median raphe nucleus) and the spinal cord (nucleus raphe magnus), with the striatum displaying the greatest sensitivity. |
1995-07-21 |
2023-08-12 |
rat |
| A Adell, R D Myer. 5-HT, dopamine, norepinephrine, and related metabolites in brain of low alcohol drinking (LAD) rats shift after chronic intra-hippocampal infusion of harman. Neurochemical research. vol 20. issue 2. 1995-07-20. PMID:7540261. |
the higher concentration of harman infused into the hippocampus elevated the level of serotonin (5-ht), both ipsilateral and contralateral to the hippocampal site of infusion, as well as in the midbrain, frontal cortex, striatum and nucleus accumbens. |
1995-07-20 |
2023-08-12 |
rat |
| S Hjorth, C S Suchowski, M P Gallowa. Evidence for 5-HT autoreceptor-mediated, nerve impulse-independent, control of 5-HT synthesis in the rat brain. Synapse (New York, N.Y.). vol 19. issue 3. 1995-07-18. PMID:7784957. |
in vitro, in cortical, hippocampal and striatal slice preparations, tfmpp (0.1-10 microm) decreased 5-ht synthesis under basal and stimulated (30 mm k+) conditions, an effect which was unaltered by prior in vivo reserpine-induced 5-ht depletion but was attenuated in the presence of 5-ht1b receptor antagonists such as methiothepin, cyanopindolol or propranolol. |
1995-07-18 |
2023-08-12 |
rat |
| T H Tsai, T F Lee, C F Chen, L C Wan. Modulatory effects of magnolol on potassium-stimulated 5-hydroxytryptamine release from rat cortical and hippocampal slices. Neuroscience letters. vol 186. issue 1. 1995-07-14. PMID:7783947. |
modulatory effects of magnolol on potassium-stimulated 5-hydroxytryptamine release from rat cortical and hippocampal slices. |
1995-07-14 |
2023-08-12 |
rat |
| T H Tsai, T F Lee, C F Chen, L C Wan. Modulatory effects of magnolol on potassium-stimulated 5-hydroxytryptamine release from rat cortical and hippocampal slices. Neuroscience letters. vol 186. issue 1. 1995-07-14. PMID:7783947. |
inclusion of magnolol (1-100 microm) had no effect on 5-ht release in hippocampal slices but elicited a dose-related inhibition on 5-ht release from cortical slices. |
1995-07-14 |
2023-08-12 |
rat |
| Y Odagaki, K Fux. 5-HT1A receptor-mediated activation of high-affinity GTPase in rat hippocampal membranes. European journal of pharmacology. vol 288. issue 3. 1995-07-11. PMID:7774684. |
5-hydroxytryptamine (5-ht) stimulated the high-affinity gtpase activity in hippocampus, but not in striatum, in a concentration-dependent manner with an ec50 value of 18 nm and maximal percent stimulation of 13.9%. |
1995-07-11 |
2023-08-12 |
rat |
| G Piñeyro, L Deveault, C de Montigny, P Blie. Effect of prolonged administration of tianeptine on 5-HT neurotransmission: an electrophysiological study in the rat hippocampus and dorsal raphe. Naunyn-Schmiedeberg's archives of pharmacology. vol 351. issue 2. 1995-07-06. PMID:7770094. |
effect of prolonged administration of tianeptine on 5-ht neurotransmission: an electrophysiological study in the rat hippocampus and dorsal raphe. |
1995-07-06 |
2023-08-12 |
rat |
| G Piñeyro, L Deveault, C de Montigny, P Blie. Effect of prolonged administration of tianeptine on 5-HT neurotransmission: an electrophysiological study in the rat hippocampus and dorsal raphe. Naunyn-Schmiedeberg's archives of pharmacology. vol 351. issue 2. 1995-07-06. PMID:7770094. |
the present results indicate that, administered at a dose known to stimulate 5-ht reuptake (20 mg/kg/day, s.c.; by minipump), and for a period of time (14 days) for which other antidepressant treatments have been shown to enhance 5-ht function, tianeptine does not modify the efficacy of 5-ht synaptic transmission in the rat hippocampus. |
1995-07-06 |
2023-08-12 |
rat |
| H L Haas, O A Sergueeva, V S Vorobjev, I N Sharonov. Subcortical modulation of synaptic plasticity in the hippocampus. Behavioural brain research. vol 66. issue 1-2. 1995-06-29. PMID:7755897. |
furthermore long-lasting potentiations of synaptic transmission and excitability following brief exposures of hippocampal slices to histamine, noradrenaline, and serotonin are mediated by cyclic amp and presumably protein kinase a. |
1995-06-29 |
2023-08-12 |
mouse |
| X O Zhu, N McNaughto. The interaction of serotonin depletion with anxiolytics and antidepressants on reticular-elicited hippocampal RSA. Neuropharmacology. vol 33. issue 12. 1995-06-26. PMID:7760982. |
the interaction of serotonin depletion with anxiolytics and antidepressants on reticular-elicited hippocampal rsa. |
1995-06-26 |
2023-08-12 |
rat |
| S E File, N Andrews, M al-Farhan, P Y W. The role of 5-HT in the anxiogenic effects of acute ethanol withdrawal and in the long-lasting cognitive deficits. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. vol 2. 1995-06-22. PMID:7748345. |
there was a significant increase in potassium-stimulated release of 3h-[5-ht] from hippocampal slices taken from rats withdrawn from chronic ethanol treatment, compared with control-treated rats. |
1995-06-22 |
2023-08-12 |
rat |
| J E Sprague, D E Nichol. The monoamine oxidase-B inhibitor L-deprenyl protects against 3,4-methylenedioxymethamphetamine-induced lipid peroxidation and long-term serotonergic deficits. The Journal of pharmacology and experimental therapeutics. vol 273. issue 2. 1995-06-19. PMID:7538579. |
3,4-methylenedioxymethamphetamine (mdma)-induced serotonergic neurotoxicity was assessed in the striatum, hippocampus and frontal cortex of rats by using [3h]paroxetine binding to label serotonin (5-ht) uptake sites and 5-ht and 5-hydroxyindoleacetic acid (5-hiaa) levels as markers of serotonergic function. |
1995-06-19 |
2023-08-12 |
rat |
| J E Sprague, D E Nichol. The monoamine oxidase-B inhibitor L-deprenyl protects against 3,4-methylenedioxymethamphetamine-induced lipid peroxidation and long-term serotonergic deficits. The Journal of pharmacology and experimental therapeutics. vol 273. issue 2. 1995-06-19. PMID:7538579. |
another experiment confirmed that a significant fraction of [3h]dopamine uptake into hippocampal synaptosomes was blocked by 500 nm fluoxetine, a selective 5-ht uptake inhibitor. |
1995-06-19 |
2023-08-12 |
rat |
| M Puig de Parada, M A Parada, E Pothos, B G Hoebe. d-fenfluramine, but not d-norfenfluramine, uses calcium to increase extracellular serotonin. Life sciences. vol 56. issue 22. 1995-06-13. PMID:7746089. |
microdialysis in the hippocampus of freely moving rats was used to assess extracellular serotonin (5-ht) in response to local infusion of d-fenfluramine and its metabolite d-norfenfluramine with and without local calcium depletion. |
1995-06-13 |
2023-08-12 |
rat |
| M H Baf, M N Subhash, K M Lakshmana, B S Ra. The effect of chronic chlorpromazine administration on monoamine levels in various regions of rat brain. Neurochemical research. vol 20. issue 1. 1995-06-07. PMID:7739759. |
ne and 5-ht levels were increased only in hippocampus by 15% (p < 0.01) and 16% (p < 0.01) respectively. |
1995-06-07 |
2023-08-12 |
rat |
| A M Bratt, J C Cassel, B Neufang, P L Greene, R Jackisch, G Hertting, B E Wil. Behavioural and neurochemical effects of superior cervical ganglionectomy in rats with septo-hippocampal lesions. Experimental brain research. vol 102. issue 3. 1995-06-06. PMID:7737390. |
neurochemical analyses measuring choline acetyltransferase (chat) activity, high-affinity choline (hacu) and noradrenaline uptake by hippocampal synaptosomes (hanu), hippocampal noradrenaline ([na]), serotonin ([5-ht]) and 5-hydroxyindoleacetic acid ([5-hiaa]) concentrations were carried out in a dorsal, a "middle" and a ventral region of the hippocampus. |
1995-06-06 |
2023-08-12 |
rat |
| A M Bratt, J C Cassel, B Neufang, P L Greene, R Jackisch, G Hertting, B E Wil. Behavioural and neurochemical effects of superior cervical ganglionectomy in rats with septo-hippocampal lesions. Experimental brain research. vol 102. issue 3. 1995-06-06. PMID:7737390. |
scgx in the presence of the fifo lesion significantly reduced [na] in the middle region of the hippocampus, as compared to scgx rats, and contributed to a restoration of lesion-induced depletions in [5-ht] and [5-hiaa] in the middle and ventral hippocampal regions, whilst failing to elicit any behavioural changes at either time point. |
1995-06-06 |
2023-08-12 |
rat |