| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Gobbi, A Bergami, C Caltavuturo, F D Valle, T Mennini, S Cacci. Effects of repeated oral doses of dexnorfenfluramine on 5-HT levels and 5-HT uptake sites in rat brain. Neuroscience letters. vol 219. issue 1. 1997-03-14. PMID:8961290. |
at this longer time while the decrease in hippocampal 5-ht levels and cortical 5-ht uptake sites remained essentially constant, cortical and striatal 5-ht levels were lowered less than at 2 h, suggesting a return toward control values. |
1997-03-14 |
2023-08-12 |
rat |
| N N Kudriavtseva, T G Amstislavskaia, D F Avgustinovich, I V Bakshtanovskaia, T V Lipina, O V Gorbach, L A Koriakin. [The effect of the repeated experience of victories and defeats in social conflicts on the function of the brain serotoninergic system in male mice]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 46. issue 6. 1997-03-13. PMID:9054161. |
repeated defeats in social confrontations were accompanied by an increase in 5-ht level in the amygdala and increase of 5-hiaa/5-ht index in the hippocampus in comparison with controls. |
1997-03-13 |
2023-08-12 |
mouse |
| C Sur, H Betz, P Schlos. Immunocytochemical detection of the serotonin transporter in rat brain. Neuroscience. vol 73. issue 1. 1997-03-11. PMID:8783244. |
we also found strong expression of serotonin transporter in the stratum oriens of area ca3 and, to a lesser extent, in the stratum oriens of ca1 and the stratum lacunosum molecular of ca1-ca3 regions of the hippocampus. |
1997-03-11 |
2023-08-12 |
rat |
| P W Burnet, C P Chen, S McGowan, M Franklin, P J Harriso. The effects of clozapine and haloperidol on serotonin-1A, -2A and -2C receptor gene expression and serotonin metabolism in the rat forebrain. Neuroscience. vol 73. issue 2. 1997-03-11. PMID:8783268. |
the treatment markedly decreased serotonin and 5-hydroxyindoleacetic acid concentrations in striatum with similar trends in cortex and hippocampus. |
1997-03-11 |
2023-08-12 |
rat |
| P W Burnet, C P Chen, S McGowan, M Franklin, P J Harriso. The effects of clozapine and haloperidol on serotonin-1A, -2A and -2C receptor gene expression and serotonin metabolism in the rat forebrain. Neuroscience. vol 73. issue 2. 1997-03-11. PMID:8783268. |
haloperidol administration did not affect the expression of the three serotonin receptors, but was associated with a modest reduction of striatal and hippocampal 5-hydroxyindoleacetic acid. |
1997-03-11 |
2023-08-12 |
rat |
| M B Assié, W Koe. Possible in vivo 5-HT reuptake blocking properties of 8-OH-DPAT assessed by measuring hippocampal extracellular 5-HT using microdialysis in rats. British journal of pharmacology. vol 119. issue 5. 1997-03-10. PMID:8922730. |
possible in vivo 5-ht reuptake blocking properties of 8-oh-dpat assessed by measuring hippocampal extracellular 5-ht using microdialysis in rats. |
1997-03-10 |
2023-08-12 |
rat |
| M B Assié, W Koe. Possible in vivo 5-HT reuptake blocking properties of 8-OH-DPAT assessed by measuring hippocampal extracellular 5-HT using microdialysis in rats. British journal of pharmacology. vol 119. issue 5. 1997-03-10. PMID:8922730. |
to study the functional consequences of this property, the effects of 8-oh-dpat were compared with those of the 5-ht reuptake inhibitors, paroxetine and clomipramine, and of the 5-ht1a receptor agonist flesinoxan, in vitro on 5-ht reuptake, and in vivo on the extracellular concentration of 5-ht by use of microdialysis, in rat hippocampus. |
1997-03-10 |
2023-08-12 |
rat |
| M B Assié, W Koe. Possible in vivo 5-HT reuptake blocking properties of 8-OH-DPAT assessed by measuring hippocampal extracellular 5-HT using microdialysis in rats. British journal of pharmacology. vol 119. issue 5. 1997-03-10. PMID:8922730. |
8-oh-dpat (10 and 100 microm), paroxetine (0.1 microm) and clomipramine (1 microm), administered through the dialysis probe, significantly increased the hippocampal extracellular concentration of 5-ht. |
1997-03-10 |
2023-08-12 |
rat |
| T J Feuerstein, O Gleichauf, G B Landwehrmeye. Modulation of cortical acetylcholine release by serotonin: the role of substance P interneurons. Naunyn-Schmiedeberg's archives of pharmacology. vol 354. issue 5. 1997-03-07. PMID:8938661. |
presynaptic inhibition of hippocampal and neocortical acetylcholine (ach) release by serotonin (5-ht) has been reported in both rat and human brain. |
1997-03-07 |
2023-08-12 |
human |
| T J Feuerstein, O Gleichauf, G B Landwehrmeye. Modulation of cortical acetylcholine release by serotonin: the role of substance P interneurons. Naunyn-Schmiedeberg's archives of pharmacology. vol 354. issue 5. 1997-03-07. PMID:8938661. |
using slices of the hippocampal formation of rat prelabelled with [3h]-overflow ([3h]-choline, superfused and depolarized electrically (2 min, 3 hz, 2 ms, 24 ma) or by k+ (20 mm) we observed that 5-ht inhibits hippocampal and entorhinal [3h]-overflow ([3h]-ach release) by 5-ht1b receptors located on cholinergic terminals. |
1997-03-07 |
2023-08-12 |
human |
| S B Auerbach, S Hjort. Effect of chronic administration of the selective serotonin (5-HT) uptake inhibitor citalopram on extracellular 5-HT and apparent autoreceptor sensitivity in rat forebrain in vivo. Naunyn-Schmiedeberg's archives of pharmacology. vol 352. issue 6. 1997-03-07. PMID:9053730. |
the results indicate that during local infusion of citalopram extracellular 5-ht was significantly higher in the dorsal hippocampus of the chronic citalopram as compared to saline treatment group. |
1997-03-07 |
2023-08-12 |
rat |
| L Romero, N Bel, F Artigas, C de Montigny, P Blie. Effect of pindolol on the function of pre- and postsynaptic 5-HT1A receptors: in vivo microdialysis and electrophysiological studies in the rat brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 15. issue 4. 1997-03-06. PMID:8887989. |
to determine whether (-)pindolol also blocked postsynaptic 5-ht1a receptors in hippocampus, 5-ht and the prototypical 5-ht1a agonist 8-oh-dpat were applied by microiontophoresis onto ca3 pyramidal neurons following the same treatment. |
1997-03-06 |
2023-08-12 |
rat |
| M B Assie, W Koe. (-)-pindolol and (+/-)-tertatolol affect rat hippocampal 5-HT levels through mechanisms involving not only 5-HT1A, but also 5-HT1B receptors. Neuropharmacology. vol 35. issue 2. 1997-03-05. PMID:8734491. |
(-)-pindolol and (+/-)-tertatolol affect rat hippocampal 5-ht levels through mechanisms involving not only 5-ht1a, but also 5-ht1b receptors. |
1997-03-05 |
2023-08-12 |
rat |
| M B Assie, W Koe. (-)-pindolol and (+/-)-tertatolol affect rat hippocampal 5-HT levels through mechanisms involving not only 5-HT1A, but also 5-HT1B receptors. Neuropharmacology. vol 35. issue 2. 1997-03-05. PMID:8734491. |
the present work examined, using in vivo microdialysis, the effects of 0.16-10 mg/kg of the beta-adrenoceptor antagonists, (-)-pindolol and (+/-)-tertatolol, which have additional 5-ht1a receptor antagonist properties, on extracellular 5-ht levels in the ventral hippocampus of chloral hydrate-anaesthetized rats. |
1997-03-05 |
2023-08-12 |
rat |
| M B Assie, W Koe. (-)-pindolol and (+/-)-tertatolol affect rat hippocampal 5-HT levels through mechanisms involving not only 5-HT1A, but also 5-HT1B receptors. Neuropharmacology. vol 35. issue 2. 1997-03-05. PMID:8734491. |
although the antagonism of the 8-oh-dpat-induced decrease of 5-ht levels by (-)-pindolol and (+/-)-tertatolol is likely to be related to their 5-ht1a antagonist properties, their ability to increase extracellular 5-ht levels when given alone may involve interactions with 5-ht1b receptors at hippocampal 5-ht terminals. |
1997-03-05 |
2023-08-12 |
rat |
| T Sharp, V Umbers, S Hjort. The role of 5-HT1A autoreceptors and alpha 1-adrenoceptors in the inhibition of 5-HT release--II NAN-190 and SDZ 216-525. Neuropharmacology. vol 35. issue 6. 1997-03-05. PMID:8887982. |
novel 5-ht1a receptor antagonists, way 100135 and way 100635, were used to test the involvement of 5-ht1a receptors in the decrease of hippocampal extracellular 5-ht induced by the 5-ht1a/alpha 1 ligands, nan-190 and sdz 216-525. |
1997-03-05 |
2023-08-12 |
rat |
| R Baskar, P U Dev. Long-term effect of prenatal exposure to low level of gamma radiation on neurophysiology of mouse. Indian journal of experimental biology. vol 34. issue 9. 1997-03-04. PMID:9014528. |
changes in locomotory activity and learning performance, and hippocampal biogenic amines (noradrenaline, na; dopamine, da; 5-hydroxytryptomine, 5-ht; and 5-hts metabolite 5-hydroxyindolacetic acid, 5-hiaa) were studied at 12 (adult) and 18 months (old) of age. |
1997-03-04 |
2023-08-12 |
mouse |
| G A Korte-Bouws, S M Korte, E R De Kloet, B Bohu. Blockade of corticosterone synthesis reduces serotonin turnover in the dorsal hippocampus of the rat as measured by microdialysis. Journal of neuroendocrinology. vol 8. issue 11. 1997-03-03. PMID:8933365. |
blockade of corticosterone synthesis reduces serotonin turnover in the dorsal hippocampus of the rat as measured by microdialysis. |
1997-03-03 |
2023-08-12 |
rat |
| G A Korte-Bouws, S M Korte, E R De Kloet, B Bohu. Blockade of corticosterone synthesis reduces serotonin turnover in the dorsal hippocampus of the rat as measured by microdialysis. Journal of neuroendocrinology. vol 8. issue 11. 1997-03-03. PMID:8933365. |
the influence of plasma corticosterone concentration on serotonin (5-ht) turnover in the dorsal hippocampus was investigated. |
1997-03-03 |
2023-08-12 |
rat |
| G A Korte-Bouws, S M Korte, E R De Kloet, B Bohu. Blockade of corticosterone synthesis reduces serotonin turnover in the dorsal hippocampus of the rat as measured by microdialysis. Journal of neuroendocrinology. vol 8. issue 11. 1997-03-03. PMID:8933365. |
therefore the present results support the hypothesis that corticosterone through glucocorticoid receptor activation enhances 5-ht synthesis rate and release in the dorsal hippocampus. |
1997-03-03 |
2023-08-12 |
rat |