| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F F Matos, C Korpinen, F D Yocc. 5-HT1A receptor agonist effects of BMY-14802 on serotonin release in dorsal raphe and hippocampus. European journal of pharmacology. vol 317. issue 1. 1997-04-02. PMID:8982718. |
systemic injections of 5-20 mg/kg bmy-14802 induced a simultaneous dose-dependent decrease in 5-ht and markedly increased the dopamine metabolite, hva concentrations in dialysates from dorsal raphe and hippocampus. |
1997-04-02 |
2023-08-12 |
rat |
| F F Matos, C Korpinen, F D Yocc. 5-HT1A receptor agonist effects of BMY-14802 on serotonin release in dorsal raphe and hippocampus. European journal of pharmacology. vol 317. issue 1. 1997-04-02. PMID:8982718. |
the 5-ht decreases in dorsal raphe and hippocampus produced by bmy-14802 were completely antagonized by pretreatment with 1.0 mg/kg of the specific 5-ht1a antagonist, way-100635 (n-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-n-(2-pyridinyl) cyclohexanecarboxamide trihydrochloride). |
1997-04-02 |
2023-08-12 |
rat |
| F F Matos, C Korpinen, F D Yocc. 5-HT1A receptor agonist effects of BMY-14802 on serotonin release in dorsal raphe and hippocampus. European journal of pharmacology. vol 317. issue 1. 1997-04-02. PMID:8982718. |
these data indicate that bmy-14802 decreases dorsal raphe and hippocampal release of 5-ht by interaction with somatodendritic 5-ht1a receptors in the raphe nuclei and suggest that this compound is a potential anxiolytic. |
1997-04-02 |
2023-08-12 |
rat |
| L E Rueter, B L Jacob. A microdialysis examination of serotonin release in the rat forebrain induced by behavioral/environmental manipulations. Brain research. vol 739. issue 1-2. 1997-04-01. PMID:8955925. |
the present study investigated this issue by employing in vivo microdialysis to examine 5-ht release in the hippocampus, corpus striatum, amygdala, and prefrontal cortex of the rat during manipulations that induced varying behavioral and physiological responses. |
1997-04-01 |
2023-08-12 |
rat |
| F Marrosu, C A Fornal, C W Metzler, B L Jacob. 5-HT1A agonists induce hippocampal theta activity in freely moving cats: role of presynaptic 5-HT1A receptors. Brain research. vol 739. issue 1-2. 1997-04-01. PMID:8955939. |
our results suggest that preferential activation of presynaptic 5-ht1a receptors, and subsequent inhibition of serotonin neurotransmission, facilitates the appearance of hippocampal theta activity in awake cats. |
1997-04-01 |
2023-08-12 |
Not clear |
| K P Datla, G Curzo. Effect of p-chlorophenylalanine at moderate dosage on 5-HT and 5-HIAA concentrations in brain regions of control and p-chloroamphetamine treated rats. Neuropharmacology. vol 35. issue 3. 1997-03-26. PMID:8783206. |
as per cent decreases of 5-hiaa were greater than those of 5-ht in cortex, striatum and hippocampus 5-hiaa/5-ht ratios fell, suggesting that partial inhibition of 5-ht synthesis by pcpa increases 5-ht conservation in these terminal regions. |
1997-03-26 |
2023-08-12 |
rat |
| K P Datla, G Curzo. Effect of p-chlorophenylalanine at moderate dosage on 5-HT and 5-HIAA concentrations in brain regions of control and p-chloroamphetamine treated rats. Neuropharmacology. vol 35. issue 3. 1997-03-26. PMID:8783206. |
the pca given without subsequent pcpa treatment decreased 5-ht and 5-hiaa so that 5-ht fell by about 70% in the cortex, striatum and hippocampus, 55% in the brain stem but only by 27% in the hypothalamus. |
1997-03-26 |
2023-08-12 |
rat |
| A Dugar, J M Lakosk. Serotonergic function of aging hippocampal CA3 pyramidal neurons: electrophysiological assessment following administration of 5,7-dihydroxytryptamine in the fimbria-fornix and cingulum bundle. Journal of neuroscience research. vol 47. issue 1. 1997-03-26. PMID:8981238. |
serotonergic (5-hydroxytryptamine; 5-ht) neurotransmission has been implicated in the regulation of cognitive function and this neurotransmitter system may underlie selective neuronal degeneration found in the aging hippocampus. |
1997-03-26 |
2023-08-12 |
rat |
| A Dugar, J M Lakosk. Serotonergic function of aging hippocampal CA3 pyramidal neurons: electrophysiological assessment following administration of 5,7-dihydroxytryptamine in the fimbria-fornix and cingulum bundle. Journal of neuroscience research. vol 47. issue 1. 1997-03-26. PMID:8981238. |
age-dependent changes in 5-ht function of hippocampal ca3 subfield pyramidal neurons were evaluated in female fischer 344 rats (2 and 17 months) following denervation of the serotonergic afferents to the dorsal hippocampus using the neurotoxin 5,7-dihydroxytryptamine (5,7-dht). |
1997-03-26 |
2023-08-12 |
rat |
| A H Lau, G D Fry. Acute and chronic actions of ethanol on CA1 hippocampal responses to serotonin. Brain research. vol 731. issue 1-2. 1997-03-25. PMID:8883849. |
acute and chronic actions of ethanol on ca1 hippocampal responses to serotonin. |
1997-03-25 |
2023-08-12 |
rat |
| A H Lau, G D Fry. Acute and chronic actions of ethanol on CA1 hippocampal responses to serotonin. Brain research. vol 731. issue 1-2. 1997-03-25. PMID:8883849. |
the effects of acute or chronic ethanol on serotonin (5-ht)-induced membrane hyperpolarization and inhibition of the slow ca2(+)-dependent after hyperpolarization (sahp) were recorded in rat ca1 pyramidal neurons in hippocampal slices using sharp intracellular electrodes. |
1997-03-25 |
2023-08-12 |
rat |
| A H Lau, G D Fry. Acute and chronic actions of ethanol on CA1 hippocampal responses to serotonin. Brain research. vol 731. issue 1-2. 1997-03-25. PMID:8883849. |
pyramidal neurons in hippocampal slices prepared from ethanol-dependent animals showed no obvious signs of withdrawal related hyperexcitability and neither concentration-dependent membrane hyperpolarization nor sahp inhibition caused by 5-ht were significantly changed from responses in controls. |
1997-03-25 |
2023-08-12 |
rat |
| M Morales, E Battenberg, L de Lecea, F E Bloo. The type 3 serotonin receptor is expressed in a subpopulation of GABAergic neurons in the rat neocortex and hippocampus. Brain research. vol 731. issue 1-2. 1997-03-25. PMID:8883870. |
the co-existence of 5-ht3r and gaba in cortical and hippocampal neurons indicates that serotonin, via 5-ht3r, can affect gaba release and suggests the participation of 5-ht3r in the inhibitory regulation of forebrain neurons. |
1997-03-25 |
2023-08-12 |
rat |
| S Hjorth, H J Bengtsson, S Milan. Raphe 5-HT1A autoreceptors, but not postsynaptic 5-HT1A receptors or beta-adrenoceptors, restrain the citalopram-induced increase in extracellular 5-hydroxytryptamine in vivo. European journal of pharmacology. vol 316. issue 1. 1997-03-21. PMID:8982649. |
in vivo microdialysis in rat ventral hippocampus was used (i) to verify the importance of 5-ht1a autoreceptors in the raphe as targets for drugs that enhance the citalopram-induced elevation of forebrain 5-hydroxytryptamine (5-ht), and (ii) to further examine the specificity of (-)-penbutolol in this regard. |
1997-03-21 |
2023-08-12 |
rat |
| S Hjorth, H J Bengtsson, S Milan. Raphe 5-HT1A autoreceptors, but not postsynaptic 5-HT1A receptors or beta-adrenoceptors, restrain the citalopram-induced increase in extracellular 5-hydroxytryptamine in vivo. European journal of pharmacology. vol 316. issue 1. 1997-03-21. PMID:8982649. |
the selective 5-ht1a receptor antagonist way100635 (s.c., or intra-raphe) or the mixed 5-ht1a/1b/beta-adrenoceptor antagonist (-)-penbutolol (s.c.), potentiated the citalopram-induced 5-ht rise, whereas local "reverse' dialysis of way100635 into the ventral hippocampus did not. |
1997-03-21 |
2023-08-12 |
rat |
| M B Viana, R Silveira, F G Graef. D-fenfluramine selectively releases 5-HT from dorsal raphe terminals. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 29. issue 5. 1997-03-20. PMID:9033815. |
male wistar rats, 180-200 g, were implanted with microdialysis probes ir the amygdala (am; n = 5) and dorsal hippocampus (dh; n = 6) and 5-ht levels were measured by electrochemical detection. |
1997-03-20 |
2023-08-12 |
rat |
| R Meeusen, K Thorré, F Chaouloff, S Sarre, K De Meirleir, G Ebinger, Y Michott. Effects of tryptophan and/or acute running on extracellular 5-HT and 5-HIAA levels in the hippocampus of food-deprived rats. Brain research. vol 740. issue 1-2. 1997-03-19. PMID:8973821. |
effects of tryptophan and/or acute running on extracellular 5-ht and 5-hiaa levels in the hippocampus of food-deprived rats. |
1997-03-19 |
2023-08-12 |
rat |
| R Meeusen, K Thorré, F Chaouloff, S Sarre, K De Meirleir, G Ebinger, Y Michott. Effects of tryptophan and/or acute running on extracellular 5-HT and 5-HIAA levels in the hippocampus of food-deprived rats. Brain research. vol 740. issue 1-2. 1997-03-19. PMID:8973821. |
the present microdialysis study has examined whether exercise-elicited increases in brain tryptophan availability (and in turn 5-ht synthesis) alter 5-ht release in the hippocampus of food-deprived rats. |
1997-03-19 |
2023-08-12 |
rat |
| R Meeusen, K Thorré, F Chaouloff, S Sarre, K De Meirleir, G Ebinger, Y Michott. Effects of tryptophan and/or acute running on extracellular 5-HT and 5-HIAA levels in the hippocampus of food-deprived rats. Brain research. vol 740. issue 1-2. 1997-03-19. PMID:8973821. |
this study indicates that exercise stimulates 5-ht release in the hippocampus of fasted rats, and that a pretreatment with tryptophan (at a dose increasing extracellular 5-ht levels) amplifies exercise-induced 5-ht release. |
1997-03-19 |
2023-08-12 |
rat |
| Y Qiu, Y Peng, J Wan. Immunoregulatory role of neurotransmitters. Advances in neuroimmunology. vol 6. issue 3. 1997-03-18. PMID:8968422. |
during the phases of days 2-7 post-immunization, the metabolic alterations of na, 5-ht and da emerged in the cns and the lymphoid organs of rats, which mainly exhibited that in the peak periods of the antibody response, the metabolism of the monoamine neurotransmitters in the hypothalamus and hippocampus was markedly increased, but na content in the spleen and thymus was significantly decreased. |
1997-03-18 |
2023-08-12 |
rat |