| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Takeo, H Hayashi, M Tadokoro, K Takagi, K Miyake, N Takagi, S Oshikaw. Effects of nebracetam on synaptosomal monoamine uptake of striatal and hippocampal regions in rats. Biological & pharmaceutical bulletin. vol 20. issue 4. 1997-07-03. PMID:9145210. |
a significant reduction in dopamine uptake in the striatum and serotonin uptake in the hippocampus was seen at concentrations of 100 microm or above. |
1997-07-03 |
2023-08-12 |
rat |
| S Takeo, H Hayashi, M Tadokoro, K Takagi, K Miyake, N Takagi, S Oshikaw. Effects of nebracetam on synaptosomal monoamine uptake of striatal and hippocampal regions in rats. Biological & pharmaceutical bulletin. vol 20. issue 4. 1997-07-03. PMID:9145210. |
in in vivo microdialysis study, there were no appreciable changes in the extracellular concentrations of striatal dopamine and hippocampal serotonin when this agent at a dose of 30 mg/kg, which was effective in improving ischemic brain energy metabolism, was applied i.p. |
1997-07-03 |
2023-08-12 |
rat |
| R K Dishman, K J Renner, S D Youngstedt, T G Reigle, B N Bunnell, K A Burke, H S Yoo, E H Mougey, J L Meyerhof. Activity wheel running reduces escape latency and alters brain monoamine levels after footshock. Brain research bulletin. vol 42. issue 5. 1997-07-01. PMID:9092882. |
brain concentrations of norepinephrine (ne), dopamine (da), dihydroxyphenylacetic acid (dopac), 5-hydroxytryptamine (5-ht), and 5-hydroxyindole acetic acid (5-hiaa) were assayed in the locus coeruleus (lc), dorsal raphe (dr), central amygdala (ac), hippocampus (ca1), arcuate nucleus, paraventricular nucleus (pvn), and midbrain central gray. |
1997-07-01 |
2023-08-12 |
rat |
| A Dinopoulos, I Dori, J G Parnavela. The serotonin innervation of the basal forebrain shows a transient phase during development. Brain research. Developmental brain research. vol 99. issue 1. 1997-06-30. PMID:9088564. |
these findings suggest that the formation of synaptic connections by serotonin axons in the basal forebrain shows two distinct phases in postnatal development: exuberant synapses present in the first two weeks of life may be related to the involvement of serotonin in the maturation of this area, whereas synapses formed later in development may affect the functional state of basal forebrain projections to the neocortex and hippocampus. |
1997-06-30 |
2023-08-12 |
rat |
| R Lew, B Weisenberg, G Vosmer, L S Seide. Combined phentermine/fenfluramine administration enhances depletion of serotonin from central terminal fields. Synapse (New York, N.Y.). vol 26. issue 1. 1997-06-27. PMID:9097403. |
combined administration of phen/fen (5 mg/kg/3.125 mg/kg and 20 mg/kg/3.125 mg/kg) caused significantly greater reductions of 5-ht levels in the striatum, nucleus accumbens/olfactory tubercle, hypothalamus, amygdala, frontal parietal cortex, and hippocampus than either drug alone. |
1997-06-27 |
2023-08-12 |
rat |
| S S al-Zahrani, A S al-Ruwaitea, M Y Ho, C M Bradshaw, E Szabad. Destruction of central noradrenergic neurones with DSP4 impairs the acquisition of temporal discrimination but does not affect memory for duration in a delayed conditional discrimination task. Psychopharmacology. vol 130. issue 2. 1997-06-26. PMID:9106915. |
the concentrations of noradrenaline in the parietal cortex and hippocampus were reduced by 90% and 89% in the dsp4-treated group, compared to the levels in the control group, but the levels of dopamine, 5-hydroxytryptamine and 5-hydroxyindoleacetic acid did not differ significantly between the groups. |
1997-06-26 |
2023-08-12 |
rat |
| K Tokarski, M Bija. Antidepressant-induced adaptive changes in the effects of 5-HT, 5-HT1A and 5-HT4 agonists on the population spike recorded in hippocampal CA1 cells do not involve presynaptic effects on excitatory synaptic transmission. Polish journal of pharmacology. vol 48. issue 6. 1997-06-26. PMID:9112695. |
effects of repeated treatment with antidepressant drugs on the reactivity of ca1 neurons to 5-hydroxytryptamine (5-ht), (+/-)-8-hydroxy-2-(dipropyl-amino)-tetralin (8-oh-dpat)--the 5-ht1a receptor agonist, and the zacopride-5-ht4 receptor agonist were examined in the rat hippocampus ex vivo. |
1997-06-26 |
2023-08-12 |
rat |
| D C Morse, R F Seegal, K O Borsch, A Brouwe. Long-term alterations in regional brain serotonin metabolism following maternal polychlorinated biphenyl exposure in the rat. Neurotoxicology. vol 17. issue 3-4. 1997-06-23. PMID:9086483. |
5-hydroxyindole acetic acid (5-hiaa) concentrations and the ratio of 5-hiaa/5-hydroxytryptamine (5-ht, serotonin) were significantly increased in the lateral olfactory tract, prefrontal cortex and hippocampus on postnatal day 90 in male and female offspring following maternal pcb treatment. |
1997-06-23 |
2023-08-12 |
rat |
| C Hadjiivanova, V D Petkov, D Maslarov, A Totev, Y Panova, I Belchev. Effect of dotarizine on K(+)-stimulated [3H]-serotonin and [3H]-acetylcholine release from rat hippocampus. General pharmacology. vol 28. issue 1. 1997-06-23. PMID:9112089. |
the effect of the diphenylmethyl-piperazine derivative dotarizine on k(+)-stimulated release of [3h]serotonin ([3h]5-ht) and [3h]acethylcholine ([3h]ach) in rat hippocampal slices was studied. |
1997-06-23 |
2023-08-12 |
rat |
| J J Kim, J C Shih, K Chen, L Chen, S Bao, S Maren, S G Anagnostaras, M S Fanselow, E De Maeyer, I Seif, R F Thompso. Selective enhancement of emotional, but not motor, learning in monoamine oxidase A-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 11. 1997-06-19. PMID:9159177. |
mice deficient in monoamine oxidase a (maoa), an enzyme that metabolizes monoamines such as norepinephrine and serotonin, have elevated norepinephrine and serotonin levels in the frontal cortex, hippocampus, and cerebellum, compared with normal wild-type mice. |
1997-06-19 |
2023-08-12 |
mouse |
| L Romero, F Artiga. Preferential potentiation of the effects of serotonin uptake inhibitors by 5-HT1A receptor antagonists in the dorsal raphe pathway: role of somatodendritic autoreceptors. Journal of neurochemistry. vol 68. issue 6. 1997-06-17. PMID:9166757. |
the maximal elevations of extracellular concentration of 5-ht (5-ht(ext)) induced by the 5-ht uptake inhibitor paroxetine in forebrain were potentiated by the 5-ht1a antagonist way-100635 (1 mg/kg s.c.) in a regionally dependent manner (striatum > frontal cortex > dorsal hippocampus). |
1997-06-17 |
2023-08-12 |
Not clear |
| L Romero, F Artiga. Preferential potentiation of the effects of serotonin uptake inhibitors by 5-HT1A receptor antagonists in the dorsal raphe pathway: role of somatodendritic autoreceptors. Journal of neurochemistry. vol 68. issue 6. 1997-06-17. PMID:9166757. |
the perfusion of 50 micromol/l citalopram in the dorsal or median raphe nucleus reduced 5-ht(ext) in frontal cortex or dorsal hippocampus to 40 and 65% of baseline, respectively. |
1997-06-17 |
2023-08-12 |
Not clear |
| R T Miller, S S Lau, T J Monk. 2,5-Bis-(glutathion-S-yl)-alpha-methyldopamine, a putative metabolite of (+/-)-3,4-methylenedioxyamphetamine, decreases brain serotonin concentrations. European journal of pharmacology. vol 323. issue 2-3. 1997-06-16. PMID:9128836. |
in contrast, 2,5-bis-(glutathion-s-yl)-alpha-methyldopamine (4 x 475 nmol) decreased 5-ht levels by 24%, 65% and 30% in the striatum, hippocampus and cortex, respectively, 7 days after injection. |
1997-06-16 |
2023-08-12 |
rat |
| R A Rabin, J C Winte. Ibogaine and noribogaine potentiate the inhibition of adenylyl cyclase activity by opioid and 5-HT receptors. European journal of pharmacology. vol 316. issue 2-3. 1997-06-12. PMID:8982706. |
similarly, both compounds also potentiated the inhibition of hippocampal adenylyl cyclase activity by a maximally effective concentration of 5-hydroxytryptamine (5-ht). |
1997-06-12 |
2023-08-12 |
rat |
| B Lendvai, H Sershen, A Lajtha, E Santha, M Baranyi, E S Viz. Differential mechanisms involved in the effect of nicotinic agonists DMPP and lobeline to release [3H]5-HT from rat hippocampal slices. Neuropharmacology. vol 35. issue 12. 1997-06-12. PMID:9076756. |
differential mechanisms involved in the effect of nicotinic agonists dmpp and lobeline to release [3h]5-ht from rat hippocampal slices. |
1997-06-12 |
2023-08-12 |
rat |
| B Lendvai, H Sershen, A Lajtha, E Santha, M Baranyi, E S Viz. Differential mechanisms involved in the effect of nicotinic agonists DMPP and lobeline to release [3H]5-HT from rat hippocampal slices. Neuropharmacology. vol 35. issue 12. 1997-06-12. PMID:9076756. |
in the present study we investigated the effect of different nicotinic agonists (dimethylphenyl-piperazinium-iodide (dmpp), (-)nicotine, cytisine, (-)-lobeline, and (-)epibatidine) and antagonists (mecamylamine and dihydro-beta-erythroidine) on the release of [3h]5-ht from hippocampal slices. |
1997-06-12 |
2023-08-12 |
rat |
| B Lendvai, H Sershen, A Lajtha, E Santha, M Baranyi, E S Viz. Differential mechanisms involved in the effect of nicotinic agonists DMPP and lobeline to release [3H]5-HT from rat hippocampal slices. Neuropharmacology. vol 35. issue 12. 1997-06-12. PMID:9076756. |
the nicotinic agonists dmpp and lobeline and electrical field stimulation, released [3h]5-ht from the hippocampus; other nicotinic agonists, such as (-)-nicotine, cytisine, and (-)-epibatidine had no effect. |
1997-06-12 |
2023-08-12 |
rat |
| B Lendvai, H Sershen, A Lajtha, E Santha, M Baranyi, E S Viz. Differential mechanisms involved in the effect of nicotinic agonists DMPP and lobeline to release [3H]5-HT from rat hippocampal slices. Neuropharmacology. vol 35. issue 12. 1997-06-12. PMID:9076756. |
it is proposed that the effect of dmpp and lobeline, to enhance the release of [3h]5-ht from the hippocampus, was mediated by two different mechanisms. |
1997-06-12 |
2023-08-12 |
rat |
| A Kulikov, S Aguerre, O Berton, A Ramos, P Mormede, F Chaoulof. Central serotonergic systems in the spontaneously hypertensive and Lewis rat strains that differ in the elevated plus-maze test of anxiety. The Journal of pharmacology and experimental therapeutics. vol 281. issue 2. 1997-06-12. PMID:9152385. |
[3h]8-hydroxy-2-(di-n-pro-pylamino)tetralin binding at midbrain 5-ht1a autoreceptors and hippocampal 5-ht1a postsynaptic receptors, [3h]ketanserin binding at cortical and striatal 5-ht2a receptors and [3h]citalopram binding at midbrain and hippocampal 5-ht transporters did not vary between strains. |
1997-06-12 |
2023-08-12 |
rat |
| E K Nénonéné, F Radja, M Carli, N M van Gelder, S Afkhami-Dastjerdian, T A Reade. Alkylation of [3H]8-OH-DPAT binding sites in rat cerebral cortex and hippocampus. Neurochemical research. vol 21. issue 2. 1997-06-12. PMID:9182242. |
the binding of tritiated 8-hydroxy-2-(di-n-propyl-amino)tetralin, or [3h]8-oh-dpat, to membranes from rat cerebral cortex and hippocampus could be inhibited by serotonin (5-ht) and buspirone, and by the 5-ht antagonists propranolol, nan-190, pindolol, pindobind-5-ht(1a), way1oo135, spiperone and ritanserin. |
1997-06-12 |
2023-08-12 |
rat |