| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S J Kell. Effects of alcohol exposure and artificial rearing during development on septal and hippocampal neurotransmitters in adult rats. Alcoholism, clinical and experimental research. vol 20. issue 4. 1996-12-27. PMID:8800383. |
alcohol-exposed female rats exhibited increased hippocampal noradrenaline concentrations under stressed conditions, increased septal serotonin, and 5-hydroxyindoleacetic acid (5-hiaa) concentrations under nonstressed conditions, and decreased septal dopamine concentrations under stressed conditions. |
1996-12-27 |
2023-08-12 |
rat |
| S J Kell. Effects of alcohol exposure and artificial rearing during development on septal and hippocampal neurotransmitters in adult rats. Alcoholism, clinical and experimental research. vol 20. issue 4. 1996-12-27. PMID:8800383. |
artificially reared male rats (regardless of alcohol exposure) exhibited an increase in hippocampal noradrenaline concentrations under stressed conditions; a decrease in hippocampal 5-hiaa concentrations under nonstressed conditions; and a decrease in septal noradrenaline, serotonin, 5-hiaa, and dopamine concentrations under nonstressed conditions. |
1996-12-27 |
2023-08-12 |
rat |
| G E Torres, C L Arfken, R Andrad. 5-Hydroxytryptamine4 receptors reduce afterhyperpolarization in hippocampus by inhibiting calcium-induced calcium release. Molecular pharmacology. vol 50. issue 5. 1996-12-26. PMID:8913363. |
these results indicate that serotonin inhibits the afterhyperpolarization in the ca1 region of hippocampus by reducing the ability of extracellular calcium to trigger calcium release from intracellular stores. |
1996-12-26 |
2023-08-12 |
Not clear |
| D Mück-Seler, A Jevric-Causevic, M Diksi. Influence of fluoxetine on regional serotonin synthesis in the rat brain. Journal of neurochemistry. vol 67. issue 6. 1996-12-23. PMID:8931476. |
a single dose of fluoxetine induced a significant increase in 5-ht synthesis in the visual, auditory, and parietal cortices, substantia nigra, hypothalamus, ventral thalamus, and dorsal hippocampus. |
1996-12-23 |
2023-08-12 |
rat |
| M K Lakshmana, T R Raj. 2, 4-dichloro phenoxy acetic acid alters monoamine levels, acetylcholinesterase activity & operant learning in rats. The Indian journal of medical research. vol 104. 1996-12-20. PMID:8898484. |
2, 4-dichloro phenoxy acetic acid (2, 4-d) was given at 100 mg/kg body weight per day by oral intubation from postnatal days 2 to 25 to assess its effect on the levels of norepinephrine (ne), dopamine (da) and 5-hydroxytryptamine (5-ht) in olfactory bulb (ob), hippocampus (hi), visual cortex (vc), cerebellum (cb) and brainstem (bs). |
1996-12-20 |
2023-08-12 |
rat |
| B C Rabin, T Z Guo, K Gregg, M Maz. Role of serotonergic neurotransmission in the hypnotic response to dexmedetomidine, an alpha 2-adrenoceptor agonist. European journal of pharmacology. vol 306. issue 1-3. 1996-12-18. PMID:8813614. |
following acute administration of dexmedetomidine, loss of righting reflex and changes in serotonin (5-hydroxytryptamine, 5-ht) and norepinephrine turnover in different brain regions (locus coeruleus and hippocampus) were assessed. |
1996-12-18 |
2023-08-12 |
rat |
| B C Rabin, T Z Guo, K Gregg, M Maz. Role of serotonergic neurotransmission in the hypnotic response to dexmedetomidine, an alpha 2-adrenoceptor agonist. European journal of pharmacology. vol 306. issue 1-3. 1996-12-18. PMID:8813614. |
dexmedetomidine (1-500 micrograms.kg-1) dose dependently reduced 5-ht and norepinephrine turnover in both the locus coeruleus and hippocampus. |
1996-12-18 |
2023-08-12 |
rat |
| L Naylor, B Dean, K Opeskin, G Pavey, C Hill, N Keks, D Copolo. Changes in the serotonin transporter in the hippocampus of subjects with schizophrenia identified using [3H]paroxetine. Journal of neural transmission (Vienna, Austria : 1996). vol 103. issue 6. 1996-12-17. PMID:8836936. |
changes in the serotonin transporter in the hippocampus of subjects with schizophrenia identified using [3h]paroxetine. |
1996-12-17 |
2023-08-12 |
human |
| M A Statnick, M L Maring-Smith, R W Clough, C Wang, J W Dailey, P C Jobe, R A Brownin. Effect of 5,7-dihydroxytryptamine on audiogenic seizures in genetically epilepsy-prone rats. Life sciences. vol 59. issue 21. 1996-12-17. PMID:8937503. |
neurochemical analysis revealed marked depletion of 5-ht in the cortex (-96%), hippocampus (-94%), thalamus (-80%), hypothalamus (-62%), midbrain (-51%) and pons-medulla (-52%) in animals that received 5,7-dht. |
1996-12-17 |
2023-08-12 |
rat |
| L E Rueter, B L Jacob. Changes in forebrain serotonin at the light-dark transition: correlation with behaviour. Neuroreport. vol 7. issue 5. 1996-12-11. PMID:8804061. |
5-ht levels increased significantly during the first half hour of dark phase in the hippocampus (45.9%), striatum (13.4%), amygdala (19.7%) and prefrontal cortex (18.4%), the increase in the hippocampus being significantly larger than those in the other areas. |
1996-12-11 |
2023-08-12 |
rat |
| W P Paré, S M Tejani-But. Effect of stress on the behavior and 5-HT system in Sprague-Dawley and Wistar Kyoto rat strains. Integrative physiological and behavioral science : the official journal of the Pavlovian Society. vol 31. issue 2. 1996-12-06. PMID:8809595. |
sd rats revealed a modest increase in 5-ht transporter (5-htt) sites in the cortex; wky rats revealed a decrease in 5-htt sites in the cortex and the hippocampus. |
1996-12-06 |
2023-08-12 |
rat |
| B Dean, W Hayes, K Opeskin, L Naylor, G Pavey, C Hill, N Keks, D L Copolo. Serotonin2 receptors and the serotonin transporter in the schizophrenic brain. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788497. |
by contrast, [3h]paroxetine binds to the serotonin transporter and therefore our data suggest that the serotonin transporter is altered in the hippocampus of subjects with schizophrenia. |
1996-12-04 |
2023-08-12 |
human |
| S Hjorth, S B Auerbac. 5-HT1A autoreceptors and the mode of action of selective serotonin reuptake inhibitors (SSRI). Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788519. |
with 5-ht reuptake first blocked by local 'reverse-dialysis' infusion of citalopram (1 microm) into the hippocampus, acute systemic administration of citalopram or paroxetine resulted in a marked decrease in hippocampal 5-ht overflow. |
1996-12-04 |
2023-08-12 |
rat |
| T D Patel, E C Azmitia, F C Zho. Increased 5-HT1A receptor immunoreactivity in the rat hippocampus following 5,7-dihydroxytryptamine lesions in the cingulum bundle and fimbria-fornix. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788527. |
serotonin (5-ht) projections from the ascending raphe nuclei reach the dorsal hippocampus via the cingulum bundle (cb) and fimbria-fornix (ff). |
1996-12-04 |
2023-08-12 |
rat |
| T D Patel, E C Azmitia, F C Zho. Increased 5-HT1A receptor immunoreactivity in the rat hippocampus following 5,7-dihydroxytryptamine lesions in the cingulum bundle and fimbria-fornix. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788527. |
microinjection of the serotonergic neurotoxin 5,7-dihydroxytryptamine (5,7-dht) into the cb and ff produces a significant decrease in the density of 5-ht immunoreactive fibers in the hippocampus as early as 3 days postlesion (zhou, f.c. |
1996-12-04 |
2023-08-12 |
rat |
| T D Patel, E C Azmitia, F C Zho. Increased 5-HT1A receptor immunoreactivity in the rat hippocampus following 5,7-dihydroxytryptamine lesions in the cingulum bundle and fimbria-fornix. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788527. |
these findings demonstrate that 5-ht denervation in the hippocampus is followed by increased expression of the 5-ht1a receptor protein. |
1996-12-04 |
2023-08-12 |
rat |
| A Fletcher, E A Forster, D J Bill, G Brown, I A Cliffe, J E Hartley, D E Jones, A McLenachan, K J Stanhope, D J Critchley, K J Childs, V C Middlefell, L Lanfumey, R Corradetti, A M Laporte, H Gozlan, M Hamon, C T Douris. Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788530. |
in vitro electrophysiological studies demonstrated that way-100635 had no 5-ht1a receptor agonist actions, but dose-dependently blocked the effects of agonists at both the postsynaptic 5-ht1a receptor in the ca1 region of the hippocampus, and the somatodendritic 5-ht1a receptor located on dorsal raphe 5-ht neurones. |
1996-12-04 |
2023-08-12 |
mouse |
| P W Burnet, I N Mefford, C C Smith, P W Gold, E M Sternber. Hippocampal 5-HT1A receptor binding site densities, 5-HT1A receptor messenger ribonucleic acid abundance and serotonin levels parallel the activity of the hypothalamo-pituitary-adrenal axis in rats. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788533. |
hippocampal 5-ht1a receptor binding site densities, 5-ht1a receptor messenger ribonucleic acid abundance and serotonin levels parallel the activity of the hypothalamo-pituitary-adrenal axis in rats. |
1996-12-04 |
2023-08-12 |
rat |
| P W Burnet, I N Mefford, C C Smith, P W Gold, E M Sternber. Hippocampal 5-HT1A receptor binding site densities, 5-HT1A receptor messenger ribonucleic acid abundance and serotonin levels parallel the activity of the hypothalamo-pituitary-adrenal axis in rats. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788533. |
the levels of hippocampal 5-ht in fischer f344 rats were significantly greater than levels detected in the same regions for the other two strains. |
1996-12-04 |
2023-08-12 |
rat |
| P W Burnet, I N Mefford, C C Smith, P W Gold, E M Sternber. Hippocampal 5-HT1A receptor binding site densities, 5-HT1A receptor messenger ribonucleic acid abundance and serotonin levels parallel the activity of the hypothalamo-pituitary-adrenal axis in rats. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788533. |
we conclude that hippocampal 5-ht1a receptor densities and 5-ht levels in the rat parallel the the activity and responsiveness of the hypthalamopituitary-adrenal axis. |
1996-12-04 |
2023-08-12 |
rat |