| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Okada, T Hirano, K Mizuno, Y Kawata, K Wada, T Murakami, H Tasaki, S Kanek. Effects of carbamazepine on hippocampal serotonergic system. Epilepsy research. vol 31. issue 3. 1998-11-02. PMID:9722029. |
after chronic administration, 25 mg/kg/day cbz increased hippocampal total levels of 5-ht, 5-htp and 5-hiaa, whereas 100 mg/kg/day cbz decreased all of these total levels. |
1998-11-02 |
2023-08-12 |
rat |
| K T Lu, P W Gea. Endogenous serotonin inhibits epileptiform activity in rat hippocampal CA1 neurons via 5-hydroxytryptamine1A receptor activation. Neuroscience. vol 86. issue 3. 1998-10-29. PMID:9692713. |
the modulatory effects of endogenous serotonin on the synaptic transmission and epileptiform activity were studied in the rat hippocampus with the use of extracellular and intracellular recording techniques. |
1998-10-29 |
2023-08-12 |
rat |
| K T Lu, P W Gea. Endogenous serotonin inhibits epileptiform activity in rat hippocampal CA1 neurons via 5-hydroxytryptamine1A receptor activation. Neuroscience. vol 86. issue 3. 1998-10-29. PMID:9692713. |
endogenous serotonin transmission in the hippocampus is therefore capable of limiting the development and propagation of seizure activity. |
1998-10-29 |
2023-08-12 |
rat |
| A Mendlin, F J Martín, B L Jacob. Involvement of dopamine D2 receptors in apomorphine-induced facilitation of forebrain serotonin output. European journal of pharmacology. vol 351. issue 3. 1998-10-29. PMID:9721020. |
the effect of systemic administration of the nonselective dopamine receptor agonist apomorphine on efflux of serotonin (5-hydroxytryptamine, 5-ht) in striatum and hippocampus of freely moving rats was examined using in vivo microdialysis. |
1998-10-29 |
2023-08-12 |
rat |
| A Bidziński, M Siemiatkowski, A Członkowska, A Tonderska, A Płaźni. The effect of serotonin depletion on motor activity habituation, and [3H]muscimol binding in the rat hippocampus. European journal of pharmacology. vol 353. issue 1. 1998-10-29. PMID:9721034. |
the effect of serotonin depletion on motor activity habituation, and [3h]muscimol binding in the rat hippocampus. |
1998-10-29 |
2023-08-12 |
rat |
| A Bidziński, M Siemiatkowski, A Członkowska, A Tonderska, A Płaźni. The effect of serotonin depletion on motor activity habituation, and [3H]muscimol binding in the rat hippocampus. European journal of pharmacology. vol 353. issue 1. 1998-10-29. PMID:9721034. |
the effect of serotonin depletion (p-chlorophenylalanine pretreatment) on habituation of exploratory motor activity, and on cortical and hippocampal [3h]muscimol binding in vitro, was examined in rats. |
1998-10-29 |
2023-08-12 |
rat |
| A Bidziński, M Siemiatkowski, A Członkowska, A Tonderska, A Płaźni. The effect of serotonin depletion on motor activity habituation, and [3H]muscimol binding in the rat hippocampus. European journal of pharmacology. vol 353. issue 1. 1998-10-29. PMID:9721034. |
it appeared that the very strong decrease in serotonin concentration abolished motor habituation in the open field and decreased [3h]muscimol binding to cortical and hippocampal brain slices. |
1998-10-29 |
2023-08-12 |
rat |
| S Ueda, M Aikawa, A Ishizuya-Oka, N Koibuchi, S Yamaoka, K Yoshimot. Age-related degeneration of the serotoninergic fibers in the zitter rat brain. Synapse (New York, N.Y.). vol 30. issue 1. 1998-10-22. PMID:9704882. |
neurochemical analysis revealed lower levels of serotonin, and 5-hydroxyindoleacetic acid, in all cortical areas (prefrontal, parietal, and occipital cortices), the caudate putamen, and the hippocampus of 12-month-old zitter rats. |
1998-10-22 |
2023-08-12 |
rat |
| S Pauli, A C Linthorst, J M Reu. Tumour necrosis factor-alpha and interleukin-2 differentially affect hippocampal serotonergic neurotransmission, behavioural activity, body temperature and hypothalamic-pituitary-adrenocortical axis activity in the rat. The European journal of neuroscience. vol 10. issue 3. 1998-10-22. PMID:9753154. |
this study was designed to investigate, using in vivo microdialysis, the effects of another endotoxin-induced proinflammatory cytokine, tumour necrosis factor-alpha, and the effects of the non-inflammatory cytokine, il-2, on hippocampal extracellular levels of serotonin. |
1998-10-22 |
2023-08-12 |
human |
| S Pauli, A C Linthorst, J M Reu. Tumour necrosis factor-alpha and interleukin-2 differentially affect hippocampal serotonergic neurotransmission, behavioural activity, body temperature and hypothalamic-pituitary-adrenocortical axis activity in the rat. The European journal of neuroscience. vol 10. issue 3. 1998-10-22. PMID:9753154. |
in contrast, intracerebroventricular administration of 500 ng, but not of 50 ng, recombinant human il-2 produced a marked increase in hippocampal extracellular concentrations of serotonin and 5-hydroxyindoleacetic acid, accompanied by a pronounced behavioural inhibition and other signs of sickness. |
1998-10-22 |
2023-08-12 |
human |
| S Pauli, A C Linthorst, J M Reu. Tumour necrosis factor-alpha and interleukin-2 differentially affect hippocampal serotonergic neurotransmission, behavioural activity, body temperature and hypothalamic-pituitary-adrenocortical axis activity in the rat. The European journal of neuroscience. vol 10. issue 3. 1998-10-22. PMID:9753154. |
interestingly, intracerebroventricular pretreatment with the il-1 receptor antagonist showed that the effects of il-2 on hippocampal serotonin were completely dependent on endogenous brain il-1. |
1998-10-22 |
2023-08-12 |
human |
| S Pauli, A C Linthorst, J M Reu. Tumour necrosis factor-alpha and interleukin-2 differentially affect hippocampal serotonergic neurotransmission, behavioural activity, body temperature and hypothalamic-pituitary-adrenocortical axis activity in the rat. The European journal of neuroscience. vol 10. issue 3. 1998-10-22. PMID:9753154. |
moreover, we postulate that activation of hippocampal serotonin release is instrumental in the full development of behavioural inhibition. |
1998-10-22 |
2023-08-12 |
human |
| J W Dailey, M E Reith, K R Steidley, J C Milbrandt, P C Job. Carbamazepine-induced release of serotonin from rat hippocampus in vitro. Epilepsia. vol 39. issue 10. 1998-10-22. PMID:9776325. |
carbamazepine-induced release of serotonin from rat hippocampus in vitro. |
1998-10-22 |
2023-08-12 |
rat |
| L E Rueter, K Kasamo, C de Montigny, P Blie. Effect of long-term administration of duloxetine on the function of serotonin and noradrenaline terminals in the rat brain. Naunyn-Schmiedeberg's archives of pharmacology. vol 357. issue 6. 1998-10-16. PMID:9686935. |
in addition, evoked release of [3h]5-ht was increased in the hippocampus, which could have been due to the desensitization of the alpha2-adrenergic heteroreceptors located on the 5-ht terminals. |
1998-10-16 |
2023-08-12 |
rat |
| L E Rueter, K Kasamo, C de Montigny, P Blie. Effect of long-term administration of duloxetine on the function of serotonin and noradrenaline terminals in the rat brain. Naunyn-Schmiedeberg's archives of pharmacology. vol 357. issue 6. 1998-10-16. PMID:9686935. |
similar to changes in 5-ht release, electrically evoked release of [3h]na was enhanced in the hippocampus and frontal cortex of rats treated chronically with duloxetine. |
1998-10-16 |
2023-08-12 |
rat |
| M C Antonelli, M Costa Lieste, R Mercado, J Hernández-. Serotonin modulation of low-affinity ouabain binding in rat brain determined by quantitative autoradiography. Neurochemical research. vol 23. issue 7. 1998-10-09. PMID:9690735. |
the results showed that 1500 nm [3h]ouabain binding was sensitive to serotonin 10(-3) m and significantly increased in the following brain regions: frontal cortex, areas ca1, ca2, and ca3 of the hippocampus, presubiculum, zona incerta, caudate putamen and the amygdaloid area, confirming and extending previous results. |
1998-10-09 |
2023-08-12 |
rat |
| N Aguirre, M Barrionuevo, B Lasheras, J Del Rí. The role of dopaminergic systems in the perinatal sensitivity to 3, 4-methylenedioxymethamphetamine-induced neurotoxicity in rats. The Journal of pharmacology and experimental therapeutics. vol 286. issue 3. 1998-10-08. PMID:9732373. |
however, only l-dopa followed by mdma caused a lasting reduction of 5-ht levels and 5-ht transporter density in the hippocampus and in the frontal cortex. |
1998-10-08 |
2023-08-12 |
rat |
| T M Cabrera-Vera, G Battagli. Prenatal exposure to fluoxetine (Prozac) produces site-specific and age-dependent alterations in brain serotonin transporters in rat progeny: evidence from autoradiographic studies. The Journal of pharmacology and experimental therapeutics. vol 286. issue 3. 1998-10-08. PMID:9732413. |
for example, prenatal fluoxetine exposure significantly altered the density of 5-ht transporters in subregions of the hypothalamus (dorsomedial nucleus, -21%; lateral hypothalamus, +21%), hippocampus (ca2, +47%; ca3, +38%), and amygdala (basolateral nucleus, +32%; medial nucleus, +44%) in prepubescent offspring. |
1998-10-08 |
2023-08-12 |
rat |
| T M Cabrera-Vera, G Battagli. Prenatal exposure to fluoxetine (Prozac) produces site-specific and age-dependent alterations in brain serotonin transporters in rat progeny: evidence from autoradiographic studies. The Journal of pharmacology and experimental therapeutics. vol 286. issue 3. 1998-10-08. PMID:9732413. |
for example, in adult control offspring, densities of 5-ht transporters were significantly greater in the cingulate cortex (+33%), basolateral amygdala (+58%), and ca1 area of the hippocampus (+78%); but significantly lower in the temporal cortex (-65%) and median raphe (-25%). |
1998-10-08 |
2023-08-12 |
rat |
| H J Bengtsson, A Kullberg, M J Millan, S Hjort. The role of 5-HT1A autoreceptors and alpha1-adrenoceptors in the modulation of 5-HT release--III. Clozapine and the novel putative antipsychotic S 16924. Neuropharmacology. vol 37. issue 3. 1998-10-02. PMID:9681933. |
in the present study, in vivo microdialysis was used to examine the effect of clozapine and s 16924 on 5-ht overflow in the rat ventral hippocampus, and to assess the relative role of putative alpha1-adrenoceptor antagonist and 5-ht1a autoreceptor agonist properties of the drugs in this regard. |
1998-10-02 |
2023-08-12 |
rat |