| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L H Tecott, S F Logue, J M Wehner, J A Kaue. Perturbed dentate gyrus function in serotonin 5-HT2C receptor mutant mice. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 25. 1999-01-14. PMID:9844009. |
serotonin systems have been implicated in the regulation of hippocampal function. |
1999-01-14 |
2023-08-12 |
mouse |
| S Zalcman, L Murray, D G Dyck, A H Greenberg, D M Nanc. Interleukin-2 and -6 induce behavioral-activating effects in mice. Brain research. vol 811. issue 1-2. 1999-01-12. PMID:9804916. |
we demonstrated that whereas il-2 increased hypothalamic and hippocampal norepinephrine (ne) utilization, and da turnover in the prefrontal cortex, il-6 induced profound elevations of serotonin (5-ht) and mesocortical dopamine (da) activity in the hippocampus and prefrontal cortex [s. zalcman, j.m. |
1999-01-12 |
2023-08-12 |
mouse |
| R Mongeau, M Weiss, C de Montigny, P Blie. Effect of acute, short- and long-term milnacipran administration on rat locus coeruleus noradrenergic and dorsal raphe serotonergic neurons. Neuropharmacology. vol 37. issue 7. 1999-01-07. PMID:9776386. |
the latter milnacipran treatment did not affect the uptake of [3h]5-ht but it inhibited that of [3h]ne by 30% in hippocampal slices. |
1999-01-07 |
2023-08-12 |
rat |
| M N Subhash, B N Srinivas, K Y Vinod, S Jagadees. Inactivation of 5-HT1A and [3H]5-HT binding sites by N-ethoxycarbonyl-2-ethoxy-1, 2-dihydroquinoline (EEDQ) in rat brain. Neurochemical research. vol 23. issue 10. 1999-01-07. PMID:9804289. |
the affinity of [3h]5-ht to 5-ht1 sites was decreased significantly in both cortex and hippocampus after exposure to eedq, without affecting the kd of 5-ht1a sites. |
1999-01-07 |
2023-08-12 |
rat |
| D J Bare, J H McKinzie, W J McBrid. Development of rapid tolerance to ethanol-stimulated serotonin release in the ventral hippocampus. Alcoholism, clinical and experimental research. vol 22. issue 6. 1999-01-04. PMID:9756042. |
development of rapid tolerance to ethanol-stimulated serotonin release in the ventral hippocampus. |
1999-01-04 |
2023-08-12 |
rat |
| D J Bare, J H McKinzie, W J McBrid. Development of rapid tolerance to ethanol-stimulated serotonin release in the ventral hippocampus. Alcoholism, clinical and experimental research. vol 22. issue 6. 1999-01-04. PMID:9756042. |
ethanol injection on the extracellular levels of serotonin (5-ht) in the ventral hippocampus (vhip) and to determine whether a single prior exposure to ethanol could alter the response to a second dose of ethanol given 24 hr later. |
1999-01-04 |
2023-08-12 |
rat |
| J E Smith, J M Lakosk. Cellular electrophysiological effects of chronic fluoxetine and duloxetine administration on serotonergic responses in the aging hippocampus. Synapse (New York, N.Y.). vol 30. issue 3. 1998-12-28. PMID:9776135. |
the pharmacological and physiological effects of chronic administration of the selective serotonin (5-hydroxytryptamine, 5-ht) reuptake inhibitor (ssri) fluoxetine and the dual 5-ht/norepinephrine (ne) reuptake inhibitor duloxetine were compared on 5-ht-mediated electrophysiological responses recorded in the hippocampus of young (3-5 months) and old (17-20 months) female fischer 344 rats. |
1998-12-28 |
2023-08-12 |
rat |
| E H Jaff. Ca2+ dependency of serotonin and dopamine release from CNS slices of chronically isolated rats. Psychopharmacology. vol 139. issue 3. 1998-12-28. PMID:9784082. |
these isolated rats enabled the study of kcl-induced release of 5-ht and da from nucleus accumbens, prefrontal cortex and hippocampal slices. |
1998-12-28 |
2023-08-12 |
rat |
| R H Belmaker, N Grisar. Magnetic stimulation of the brain in animal depression models responsive to ECS. The journal of ECT. vol 14. issue 3. 1998-12-23. PMID:9773358. |
tms caused an increase in serotonin and 5-hiaa levels in the hippocampus but not in other brain regions examined in this study. |
1998-12-23 |
2023-08-12 |
rat |
| N Haddjeri, B Seletti, F Gilbert, C de Montigny, P Blie. Effect of ergotamine on serotonin-mediated responses in the rodent and human brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 19. issue 5. 1998-12-23. PMID:9778659. |
in the rat dorsal hippocampus and dorsal raphe nucleus, the microiontophoretic application of ergotamine and 5-ht suppressed the firing activity of ca3 pyramidal neurons and 5-ht neurons, an effect antagonized by selective 5-ht1a receptor antagonists. |
1998-12-23 |
2023-08-12 |
human |
| N Haddjeri, B Seletti, F Gilbert, C de Montigny, P Blie. Effect of ergotamine on serotonin-mediated responses in the rodent and human brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 19. issue 5. 1998-12-23. PMID:9778659. |
co-application of ergotamine prevented the inhibitory action of 5-ht on the firing activity of ca3 pyramidal neurons but not of 5-ht neurons, indicating that ergotamine acted as a partial 5-ht1a receptor agonist in the dorsal hippocampus and as a full agonist at 5-ht1a autoreceptors. |
1998-12-23 |
2023-08-12 |
human |
| A Hayashi, M Nagaoka, K Yamada, Y Ichitani, Y Miake, N Okad. Maternal stress induces synaptic loss and developmental disabilities of offspring. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 16. issue 3-4. 1998-12-23. PMID:9785117. |
together with data in our previous studies, that have shown 5-ht to facilitate synapse formation and maintenance in the central nervous system, synaptic loss is suggested to occur in relation to changes of 5-ht system in the hippocampus of prenatally stressed offspring. |
1998-12-23 |
2023-08-12 |
rat |
| I Hervás, N Bel, A G Fernández, J M Palacios, F Artiga. In vivo control of 5-hydroxytryptamine release by terminal autoreceptors in rat brain areas differentially innervated by the dorsal and median raphe nuclei. Naunyn-Schmiedeberg's archives of pharmacology. vol 358. issue 3. 1998-12-22. PMID:9774218. |
however, despite a comparatively lower 5-ht1a-mediated inhibition of 5-ht release and a greater density of serotonergic uptake sites in hippocampus, the net elevation produced by the systemic administration of ssris is similar in various forebrain areas, regardless of the origin of serotonergic fibres. |
1998-12-22 |
2023-08-12 |
rat |
| I Hervás, N Bel, A G Fernández, J M Palacios, F Artiga. In vivo control of 5-hydroxytryptamine release by terminal autoreceptors in rat brain areas differentially innervated by the dorsal and median raphe nuclei. Naunyn-Schmiedeberg's archives of pharmacology. vol 358. issue 3. 1998-12-22. PMID:9774218. |
the non-selective 5-ht1 antagonist methiothepin (10 and 100 microm, dissolved in the dialysis fluid) increased extracellular 5-ht in frontal cortex and dorsal hippocampus in a concentration-dependent manner. |
1998-12-22 |
2023-08-12 |
rat |
| I Hervás, N Bel, A G Fernández, J M Palacios, F Artiga. In vivo control of 5-hydroxytryptamine release by terminal autoreceptors in rat brain areas differentially innervated by the dorsal and median raphe nuclei. Naunyn-Schmiedeberg's archives of pharmacology. vol 358. issue 3. 1998-12-22. PMID:9774218. |
the 5-ht(1b/1d) antagonist gr 127935 was ineffective at 10 microm and tended to reduce 5-ht in dorsal hippocampus at 100 microm. |
1998-12-22 |
2023-08-12 |
rat |
| I Hervás, N Bel, A G Fernández, J M Palacios, F Artiga. In vivo control of 5-hydroxytryptamine release by terminal autoreceptors in rat brain areas differentially innervated by the dorsal and median raphe nuclei. Naunyn-Schmiedeberg's archives of pharmacology. vol 358. issue 3. 1998-12-22. PMID:9774218. |
the local infusion of 100 microm methiothepin significantly elevated the extracellular 5-ht concentration to 142-173% of baseline (mean values of 260 min post-administration) in the drn, mrn, frontal cortex, striatum and hippocampus (dorsal and ventral). |
1998-12-22 |
2023-08-12 |
rat |
| I Hervás, N Bel, A G Fernández, J M Palacios, F Artiga. In vivo control of 5-hydroxytryptamine release by terminal autoreceptors in rat brain areas differentially innervated by the dorsal and median raphe nuclei. Naunyn-Schmiedeberg's archives of pharmacology. vol 358. issue 3. 1998-12-22. PMID:9774218. |
as observed in frontal cortex and dorsal hippocampus, the perfusion of 10 microm gr 127935 did not elevate 5-ht in drn. |
1998-12-22 |
2023-08-12 |
rat |
| I Hervás, N Bel, A G Fernández, J M Palacios, F Artiga. In vivo control of 5-hydroxytryptamine release by terminal autoreceptors in rat brain areas differentially innervated by the dorsal and median raphe nuclei. Naunyn-Schmiedeberg's archives of pharmacology. vol 358. issue 3. 1998-12-22. PMID:9774218. |
thus, the present data suggest that the comparable effects of ssris in drn- and mrn-innervated forebrain regions are not explained by a preferential attenuation of 5-ht release by terminal 5-ht1b autoreceptors in hippocampus, an area with a low inhibitory influence of somatodendritic 5-ht1a receptors. |
1998-12-22 |
2023-08-12 |
rat |
| M Gobbi, A Parazzoli, T Mennin. In vitro studies on the mechanism by which (+)-norfenfluramine induces serotonin and dopamine release from the vesicular storage pool. Naunyn-Schmiedeberg's archives of pharmacology. vol 358. issue 3. 1998-12-22. PMID:9774219. |
the dose-response curves of (+)-norfenfluramine-induced [3h]5-ht release were superimposable in hippocampus and hypothalamus, and also superimposable on the curve for (+)-fenfluramine-induced [3h]5-ht release; the dopamine releasing potency of (+)-norfenfluramine in the striatum was more than ten times lower. |
1998-12-22 |
2023-08-12 |
Not clear |
| K Yanai, L Z Son, M Endou, E Sakurai, O Nakagawasai, T Tadano, K Kisara, I Inoue, T Watanabe, T Watanab. Behavioural characterization and amounts of brain monoamines and their metabolites in mice lacking histamine H1 receptors. Neuroscience. vol 87. issue 2. 1998-12-21. PMID:9740406. |
the turnover rate of 5-hydroxytryptamine defined by the ratio of 5-hydroxyindoleacetic acid and 5-hydroxytryptamine was significantly increased in the cerebral cortex and hippocampus of h1 receptor null mice. |
1998-12-21 |
2023-08-12 |
mouse |