| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anibal A Arjona, Amy M Pooler, Robert K Lee, Richard J Wurtma. Effect of a 5-HT(2C) serotonin agonist, dexnorfenfluramine, on amyloid precursor protein metabolism in guinea pigs. Brain research. vol 951. issue 1. 2002-11-26. PMID:12231467. |
), a 5-ht(2b/2c) agonist, for 9 days also increased csf app(s) levels (p<0.5) when measured 2 h after the drug's last administration; hippocampal and cortical app(h) levels were unaffected. |
2002-11-26 |
2023-08-12 |
Not clear |
| Takako Yamato, Satomi Yamasaki, Yukiko Misumi, Mayuko Kino, Toshio Obata, Masahiro Aomin. Modulation of the stress response by coffee: an in vivo microdialysis study of hippocampal serotonin and dopamine levels in rat. Neuroscience letters. vol 332. issue 2. 2002-11-26. PMID:12384217. |
modulation of the stress response by coffee: an in vivo microdialysis study of hippocampal serotonin and dopamine levels in rat. |
2002-11-26 |
2023-08-12 |
rat |
| Takako Yamato, Satomi Yamasaki, Yukiko Misumi, Mayuko Kino, Toshio Obata, Masahiro Aomin. Modulation of the stress response by coffee: an in vivo microdialysis study of hippocampal serotonin and dopamine levels in rat. Neuroscience letters. vol 332. issue 2. 2002-11-26. PMID:12384217. |
restraint stress for 100 min caused a marked increase in dopamine and serotonin (5-ht) levels in the hippocampus, and then, 100 min resting (freely-moving) time reduced them to basal levels. |
2002-11-26 |
2023-08-12 |
rat |
| Elaine A Del-Bel, Sâmia Regiane Lourenço Joca, Cláudia Maria Padovan, Francisco S Guimarãe. Effects of isolation-rearing on serotonin-1A and M1-muscarinic receptor messenger RNA expression in the hipocampal formation of rats. Neuroscience letters. vol 332. issue 2. 2002-11-26. PMID:12384226. |
these results may reflect up-regulation of 5-ht1a gene transcription in response to deficits in hippocampal serotonin neurotransmission induced by social isolation. |
2002-11-26 |
2023-08-12 |
rat |
| Z Xu, F J Seidler, M M Cousins, W Slikker, T A Slotki. Adolescent nicotine administration alters serotonin receptors and cell signaling mediated through adenylyl cyclase. Brain research. vol 951. issue 2. 2002-11-25. PMID:12270507. |
adolescent nicotine decreased 5ht(2) receptor binding in brain regions containing 5ht projections (hippocampus and cerebral cortex), with selectivity for females in the cerebral cortex; regions containing 5ht cell bodies showed either an increase (midbrain in males) or no change (brainstem). |
2002-11-25 |
2023-08-12 |
rat |
| Francesca Fernandez, Sylvie Aguerre, Pierre Mormède, Francis Chaoulof. Influences of the corticotropic axis and sympathetic activity on neurochemical consequences of 3,4-methylenedioxymethamphetamine (MDMA) administration in Fischer 344 rats. The European journal of neuroscience. vol 16. issue 4. 2002-11-22. PMID:12270036. |
the respective influences of the corticotropic axis and sympathetic activity on 3,4-methylenedioxymethamphetamine (mdma, ecstasy) immediate effects on body temperature and long-term neurotoxicity, as assessed by decreases in hippocampal and striatal [(3)h]5-hydroxytryptamine ([(3)h]5-ht) reuptake, [(3)h]paroxetine binding at 5-ht transporters (5-htt), and 5-ht and 5-hydroxyindoleacetic acid (5-hiaa) levels, were examined in fischer 344 rats. |
2002-11-22 |
2023-08-12 |
rat |
| Francesca Fernandez, Sylvie Aguerre, Pierre Mormède, Francis Chaoulof. Influences of the corticotropic axis and sympathetic activity on neurochemical consequences of 3,4-methylenedioxymethamphetamine (MDMA) administration in Fischer 344 rats. The European journal of neuroscience. vol 16. issue 4. 2002-11-22. PMID:12270036. |
six days after the last injection of 10 mg/kg mdma, [(3)h]5-ht reuptake, [(3)h]paroxetine binding and 5-ht and 5-hiaa levels were decreased in the hippocampus and, to a lower extent, in striatum. |
2002-11-22 |
2023-08-12 |
rat |
| Francesca Fernandez, Sylvie Aguerre, Pierre Mormède, Francis Chaoulof. Influences of the corticotropic axis and sympathetic activity on neurochemical consequences of 3,4-methylenedioxymethamphetamine (MDMA) administration in Fischer 344 rats. The European journal of neuroscience. vol 16. issue 4. 2002-11-22. PMID:12270036. |
this pretreatment markedly reduced the amplitudes of the immediate hyperthermia and long-term declines in hippocampal [(3)h]5-ht reuptake and [(3)h]paroxetine binding at 5-htt, and in hippocampal and striatal 5-ht and 5-hiaa levels. |
2002-11-22 |
2023-08-12 |
rat |
| Erica L Unger, Pascale Mazzola-Pomietto, Dennis L Murphy, Anne M Andrew. 2'-NH(2)-MPTP [1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine] depletes serotonin and norepinephrine in rats: a comparison with 2'-CH(3)-MPTP [1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine]. The Journal of pharmacology and experimental therapeutics. vol 303. issue 2. 2002-11-22. PMID:12388632. |
four injections of 20 mg/kg 2'-nh(2)-mptp caused 80 to 90% depletions in serotonin and norepinephrine in frontal cortex and hippocampus in rats 1 week post-treatment. |
2002-11-22 |
2023-08-12 |
mouse |
| Marilyn J Duncan, Julie G Hensle. Aging alters in a region-specific manner serotonin transporter sites and 5-HT(1A) receptor-G protein interactions in hamster brain. Neuropharmacology. vol 43. issue 1. 2002-11-21. PMID:12213257. |
in the ca(1) region of hippocampus, 8-oh-dpat-stimulated [(35)s]gtp gamma s binding was increased in the older animals (% above basal, old: 141+/-21; young: 81+/-17) without changing specific [(3)h] mppf binding sites, suggesting that the capacity of 5-ht(1a) receptors to activate g proteins is enhanced. |
2002-11-21 |
2023-08-12 |
Not clear |
| Bartosz Bobula, Agnieszka Zahorodna, Krzysztof Tokarski, Grzegorz Hes. [Use of models for spontaneous paroxysmal activity in studies of adaptive changes in serotonin receptors]. Postepy higieny i medycyny doswiadczalnej. vol 56. issue 3. 2002-11-20. PMID:12194250. |
using extracellular ex vivo recording of spontaneous, epileptiform activity of neurons we determined changes in the reactivity of cortical and hippocampal slices to agonists of main subtypes 5-ht receptors, induced by repeated administration of the antidepressants. |
2002-11-20 |
2023-08-12 |
Not clear |
| Hideki Miura, Hong Qiao, Tatsuro Oht. Influence of aging and social isolation on changes in brain monoamine turnover and biosynthesis of rats elicited by novelty stress. Synapse (New York, N.Y.). vol 46. issue 2. 2002-11-19. PMID:12211090. |
changes in brain monoamines and their metabolites such as dopamine (da), serotonin (5-ht), dihydroxyphenylacetic acid (dopac), homovanilic acid (hva), and 5-hydroxyindoleacetic acid (5-hiaa) were measured in six regions: the prefrontal cortex, nucleus accumbens, hippocampus, amygdala, midbrain, and raphe nuclei. |
2002-11-19 |
2023-08-12 |
human |
| Agnieszka Zahorodna, Maria Bijak, Grzegorz Hes. Differential effects of repeated imipramine on hippocampal responsiveness to adenosine and serotonin. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 12. issue 4. 2002-11-15. PMID:12126876. |
differential effects of repeated imipramine on hippocampal responsiveness to adenosine and serotonin. |
2002-11-15 |
2023-08-12 |
rat |
| Agnieszka Zahorodna, Maria Bijak, Grzegorz Hes. Differential effects of repeated imipramine on hippocampal responsiveness to adenosine and serotonin. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 12. issue 4. 2002-11-15. PMID:12126876. |
we investigated the influence of repeated imipramine administration on 5-ht(la) and adenosine a1 receptor-mediated effects in rat hippocampal slices. |
2002-11-15 |
2023-08-12 |
rat |
| Jan Kehr, Takashi Yoshitake, Fu-Hua Wang, Haleh Razani, Lydia Gimenez-Llort, Anders Jansson, Masatoshi Yamaguchi, Sven Ove Ogre. Galanin is a potent in vivo modulator of mesencephalic serotonergic neurotransmission. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 27. issue 3. 2002-11-15. PMID:12225692. |
intraventricularly infused galanin caused a long-lasting and dose-dependent reduction of basal extracellular 5-ht levels in the ventral hippocampus of awake rats as measured by microdialysis. |
2002-11-15 |
2023-08-12 |
rat |
| Jan Kehr, Takashi Yoshitake, Fu-Hua Wang, Haleh Razani, Lydia Gimenez-Llort, Anders Jansson, Masatoshi Yamaguchi, Sven Ove Ogre. Galanin is a potent in vivo modulator of mesencephalic serotonergic neurotransmission. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 27. issue 3. 2002-11-15. PMID:12225692. |
surprisingly, galanin significantly attenuated the reduction of hippocampal 5-ht release induced by systemic injection of the 5-ht(1a) receptor agonist 8-oh-dpat. |
2002-11-15 |
2023-08-12 |
rat |
| Carina Stenfors, Svante B Ros. Evidence for involvement of 5-hydroxytryptamine(1B) autoreceptors in the enhancement of serotonin turnover in the mouse brain following repeated treatment with fluoxetine. Life sciences. vol 71. issue 24. 2002-11-14. PMID:12377268. |
the concentration of 5-hydroxytryptophan (5-htp), 5-hydroxyindoleacetic acid (5-hiaa) and 5-ht was measured in hypothalamus, hippocampus and frontal cortex after inhibition of the aromatic amino acid decarboxylase activity with m-hydroxybenzylhydrazine (nsd 1015). |
2002-11-14 |
2023-08-12 |
mouse |
| L L Morford, S L Inman-Wood, G A Gudelsky, M T Williams, C V Vorhee. Impaired spatial and sequential learning in rats treated neonatally with D-fenfluramine. The European journal of neuroscience. vol 16. issue 3. 2002-11-08. PMID:12193193. |
d-fenfluramine, a serotonin releaser, was administered to neonatal rats on postnatal days 11-20 (a stage of hippocampal development analogous to third trimester human ontogeny). |
2002-11-08 |
2023-08-12 |
human |
| L L Morford, S L Inman-Wood, G A Gudelsky, M T Williams, C V Vorhee. Impaired spatial and sequential learning in rats treated neonatally with D-fenfluramine. The European journal of neuroscience. vol 16. issue 3. 2002-11-08. PMID:12193193. |
the spatial learning effects common to all three drugs suggest that they may share a common mechanism of action, however, the effects are not related to long-lasting changes in hippocampal 5-ht levels as no differences were found in adulthood. |
2002-11-08 |
2023-08-12 |
human |
| Ulf Bickmeyer, Martin Heine, Till Manzke, Diethelm W Richte. Differential modulation of I(h) by 5-HT receptors in mouse CA1 hippocampal neurons. The European journal of neuroscience. vol 16. issue 2. 2002-11-06. PMID:12169103. |
differential modulation of i(h) by 5-ht receptors in mouse ca1 hippocampal neurons. |
2002-11-06 |
2023-08-12 |
mouse |