| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gaoyi Yao, Huifeng Yue, Yang Yun, Nan San. Chronic SO2 inhalation above environmental standard impairs neuronal behavior and represses glutamate receptor gene expression and memory-related kinase activation via neuroinflammation in rats. Environmental research. vol 137. 2015-05-04. PMID:25498917. |
in the present study, by exposing male wistar rats to so2 at 3.50 and 7.00 mg/m(3) (approximately 1225 and 2450 ppb, 4.08-8.16 (24h average concentration) times higher than the epa standard for environmental air concentrations) or filtered air for 90 days, we investigated the impact of chronic so2 inhalation on performance in morris water maze, and probed the accompanying neurobiological effects, including activity-regulated cytoskeletal associated gene (arc) and glutamate receptor gene expression, memory-related kinase level and inflammatory cytokine release in the hippocampus. |
2015-05-04 |
2023-08-13 |
rat |
| Giles My Tan, Felix Beacher, Eileen Daly, Jamie Horder, Verinder Prasher, Maria-Luisa Hanney, Robin Morris, Simon Lovestone, Kieran C Murphy, Andrew Simmons, Declan Gm Murph. Hippocampal glutamate-glutamine (Glx) in adults with Down syndrome: a preliminary study using in vivo proton magnetic resonance spectroscopy ((1)H MRS). Journal of neurodevelopmental disorders. vol 6. issue 1. 2015-05-04. PMID:25937842. |
however, the concentration of hippocampal glutamate in ds individuals with and without dementia has not previously been directly investigated. |
2015-05-04 |
2023-08-13 |
Not clear |
| Tomohisa Hosokawa, Dai Mitsushima, Rina Kaneko, Yasunori Hayash. Stoichiometry and phosphoisotypes of hippocampal AMPA-type glutamate receptor phosphorylation. Neuron. vol 85. issue 1. 2015-05-01. PMID:25533481. |
stoichiometry and phosphoisotypes of hippocampal ampa-type glutamate receptor phosphorylation. |
2015-05-01 |
2023-08-13 |
Not clear |
| Ratna Angela Sarabdjitsingh, Julie Jezequel, Natasha Pasricha, Lenka Mikasova, Amber Kerkhofs, Henk Karst, Laurent Groc, Marian Joël. Ultradian corticosterone pulses balance glutamatergic transmission and synaptic plasticity. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 39. 2015-04-30. PMID:25225407. |
by using high-resolution imaging and electrophysiological approaches, we report that a single pulse of cort to hippocampal networks causes synaptic enrichment of glutamate receptors and increased responses to spontaneously released glutamatergic vesicles, collectively abrogating the ability to subsequently induce synaptic long-term potentiation. |
2015-04-30 |
2023-08-13 |
Not clear |
| Olivia A Shipton, Mohamady El-Gaby, John Apergis-Schoute, Karl Deisseroth, David M Bannerman, Ole Paulsen, Michael M Koh. Left-right dissociation of hippocampal memory processes in mice. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 42. 2015-04-24. PMID:25246561. |
here we examined whether lateralized hippocampal memory processing is present in mice, where hemispheric asymmetry at the ca3-ca1 pyramidal neuron synapse has recently been demonstrated, with different spine morphology, glutamate receptor content, and synaptic plasticity, depending on whether afferents originate in the left or right ca3. |
2015-04-24 |
2023-08-13 |
mouse |
| Woosuk Chung, Su Yeon Choi, Eunee Lee, Haram Park, Jaeseung Kang, Hanwool Park, Yeonsoo Choi, Dongsoo Lee, Sae-Geun Park, Ryunhee Kim, Yi Sul Cho, Jeonghoon Choi, Myoung-Hwan Kim, Jong Won Lee, Seungjoon Lee, Issac Rhim, Min Whan Jung, Daesoo Kim, Yong Chul Bae, Eunjoon Ki. Social deficits in IRSp53 mutant mice improved by NMDAR and mGluR5 suppression. Nature neuroscience. vol 18. issue 3. 2015-04-20. PMID:25622145. |
treatment of irsp53(-/-) mice, which display enhanced nmda receptor (nmdar) function in the hippocampus, with memantine, an nmdar antagonist, or mpep, a metabotropic glutamate receptor 5 antagonist that indirectly inhibits nmdar function, normalized social interaction. |
2015-04-20 |
2023-08-13 |
mouse |
| Eduardo Kalinine, Eduardo Rigon Zimmer, Kamila Cagliari Zenki, Iouri Kalinine, Vanessa Kazlauckas, Clarissa Branco Haas, Gisele Hansel, Aline Rigon Zimmer, Diogo Onofre Souza, Alexandre Pastoris Müller, Luis Valmor Portel. Nandrolone-induced aggressive behavior is associated with alterations in extracellular glutamate homeostasis in mice. Hormones and behavior. vol 66. issue 2. 2015-04-19. PMID:24937439. |
each endpoint was assessed for glt-1 expression and glutamate uptake activity in the frontoparietal cortex and hippocampal tissues. |
2015-04-19 |
2023-08-13 |
mouse |
| Eduardo Kalinine, Eduardo Rigon Zimmer, Kamila Cagliari Zenki, Iouri Kalinine, Vanessa Kazlauckas, Clarissa Branco Haas, Gisele Hansel, Aline Rigon Zimmer, Diogo Onofre Souza, Alexandre Pastoris Müller, Luis Valmor Portel. Nandrolone-induced aggressive behavior is associated with alterations in extracellular glutamate homeostasis in mice. Hormones and behavior. vol 66. issue 2. 2015-04-19. PMID:24937439. |
resident males were assessed for hippocampal glutamate levels via microdialysis both prior to, and following, the introduction of intruders. |
2015-04-19 |
2023-08-13 |
mouse |
| Juan A Orellana, Rodrigo Moraga-Amaro, Raúl Díaz-Galarce, Sebastián Rojas, Carola J Maturana, Jimmy Stehberg, Juan C Sáe. Restraint stress increases hemichannel activity in hippocampal glial cells and neurons. Frontiers in cellular neuroscience. vol 9. 2015-04-17. PMID:25883550. |
these effects have been linked to glial cell activation, glutamate release and changes in neuronal plasticity and survival including atrophy of hippocampal apical dendrites, loss of synapses and neuronal death. |
2015-04-17 |
2023-08-13 |
mouse |
| Juan A Orellana, Rodrigo Moraga-Amaro, Raúl Díaz-Galarce, Sebastián Rojas, Carola J Maturana, Jimmy Stehberg, Juan C Sáe. Restraint stress increases hemichannel activity in hippocampal glial cells and neurons. Frontiers in cellular neuroscience. vol 9. 2015-04-17. PMID:25883550. |
moreover, inhibition of nmda/p2x7 receptors reduced the chronic stress-induced hemichannel opening, whereas blockade of cx43 and panx1 hemichannels fully reduced atp and glutamate release in hippocampal slices from stressed mice. |
2015-04-17 |
2023-08-13 |
mouse |
| Ana L B Zeni, Samuel Vandresen-Filho, Tharine Dal-Cim, Wagner C Martins, Daniela B Bertoldo, Marcelo Maraschin, Carla I Tasc. Aloysia gratissima prevents cellular damage induced by glutamatergic excitotoxicity. The Journal of pharmacy and pharmacology. vol 66. issue 9. 2015-04-13. PMID:24707860. |
additionally, ae and ferulic acid (fa), the major compound of ae, were tested against neurotoxicity evoked by glutamate or its n-methyl-d-aspartate receptor (nmdar) agonist, qa on hippocampal slices, in vitro. |
2015-04-13 |
2023-08-13 |
mouse |
| Yuqing Duan, Zhigao Wang, Haihui Zhang, Yuanqing He, Rong Fan, Yanxiang Cheng, Guibo Sun, Xiaobo Su. Extremely low frequency electromagnetic field exposure causes cognitive impairment associated with alteration of the glutamate level, MAPK pathway activation and decreased CREB phosphorylation in mice hippocampus: reversal by procyanidins extracted from the lotus seedpod. Food & function. vol 5. issue 9. 2015-04-13. PMID:25066354. |
extremely low frequency electromagnetic field exposure causes cognitive impairment associated with alteration of the glutamate level, mapk pathway activation and decreased creb phosphorylation in mice hippocampus: reversal by procyanidins extracted from the lotus seedpod. |
2015-04-13 |
2023-08-13 |
mouse |
| Yuqing Duan, Zhigao Wang, Haihui Zhang, Yuanqing He, Rong Fan, Yanxiang Cheng, Guibo Sun, Xiaobo Su. Extremely low frequency electromagnetic field exposure causes cognitive impairment associated with alteration of the glutamate level, MAPK pathway activation and decreased CREB phosphorylation in mice hippocampus: reversal by procyanidins extracted from the lotus seedpod. Food & function. vol 5. issue 9. 2015-04-13. PMID:25066354. |
in this study we determined whether the elf-emf (50 hz, 8 mt, 28 days) exposure induced alterations of glutamate release in mice hippocampus and explored the possible mechanism, and if lspc treatment normalized its alterations. |
2015-04-13 |
2023-08-13 |
mouse |
| Yuqing Duan, Zhigao Wang, Haihui Zhang, Yuanqing He, Rong Fan, Yanxiang Cheng, Guibo Sun, Xiaobo Su. Extremely low frequency electromagnetic field exposure causes cognitive impairment associated with alteration of the glutamate level, MAPK pathway activation and decreased CREB phosphorylation in mice hippocampus: reversal by procyanidins extracted from the lotus seedpod. Food & function. vol 5. issue 9. 2015-04-13. PMID:25066354. |
the results showed that elf-emf exposure induced the increased contents of glutamate, gaba, excessively activated nmda receptors, increasing the number of nmda receptor 2b (nr2b) and intracellular ca(2+) concentration [ca(2+)]i in hippocampus. |
2015-04-13 |
2023-08-13 |
mouse |
| Kaosheng Lv, Liang Chen, Yuanjun Li, Zenglong Li, Pengli Zheng, Yingying Liu, Jianguo Chen, Junlin Ten. Trip6 promotes dendritic morphogenesis through dephosphorylated GRIP1-dependent myosin VI and F-actin organization. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 6. 2015-04-13. PMID:25673849. |
through interaction with the glutamate receptor-interacting protein 1 (grip1) and myosin vi, trip6 is crucial for the total dendritic length and the number of primary dendrites in cultured hippocampal neurons. |
2015-04-13 |
2023-08-13 |
mouse |
| Wannan Tang, Karolina Szokol, Vidar Jensen, Rune Enger, Chintan A Trivedi, Øivind Hvalby, P Johannes Helm, Loren L Looger, Rolf Sprengel, Erlend A Nagelhu. Stimulation-evoked Ca2+ signals in astrocytic processes at hippocampal CA3-CA1 synapses of adult mice are modulated by glutamate and ATP. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 7. 2015-04-13. PMID:25698739. |
stimulation-evoked ca2+ signals in astrocytic processes at hippocampal ca3-ca1 synapses of adult mice are modulated by glutamate and atp. |
2015-04-13 |
2023-08-13 |
mouse |
| Li Yue, Huo Xiao-lin, Song Ta. The effects of chronic repetitive transcranial magnetic stimulation on glutamate and gamma-aminobutyric acid in rat brain. Brain research. vol 1260. 2015-03-30. PMID:19401169. |
results showed that the content of glutamate and gamma-aminobutyric acid increased significantly in hippocampus and striatum after chronic rtms, but reduced significantly in the hypothalamus. |
2015-03-30 |
2023-08-12 |
human |
| Alicia Raquel Rossi, Maria Florencia Angelo, Alejandro Villarreal, Jerónimo Lukin, Alberto Javier Ramo. Gabapentin administration reduces reactive gliosis and neurodegeneration after pilocarpine-induced status epilepticus. PloS one. vol 8. issue 11. 2015-03-30. PMID:24250797. |
in vitro experiments were performed in dissociated mixed hippocampal cell culture exposed to glutamate, and subsequently treated with gabapentin or vehicle. |
2015-03-30 |
2023-08-12 |
human |
| Thuy Nguyen, Tianming Yang, Mei-Lin G. Functionalized acridin-9-yl phenylamines protected neuronal HT22 cells from glutamate-induced cell death by reducing intracellular levels of free radical species. Bioorganic & medicinal chemistry letters. vol 24. issue 7. 2015-03-30. PMID:24602904. |
the in vitro neuronal cell death model based on the ht22 mouse hippocampal cell model is a convenient means of identifying compounds that protect against oxidative glutamate toxicity which plays a role in the development of certain neurodegenerative diseases. |
2015-03-30 |
2023-08-12 |
mouse |
| Abeer E Dief, Eman S Kamha, Azza M Baraka, Amany K Elshorbag. Monosodium glutamate neurotoxicity increases beta amyloid in the rat hippocampus: a potential role for cyclic AMP protein kinase. Neurotoxicology. vol 42. 2015-03-30. PMID:24769037. |
monosodium glutamate neurotoxicity increases beta amyloid in the rat hippocampus: a potential role for cyclic amp protein kinase. |
2015-03-30 |
2023-08-13 |
rat |