| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rachelle Crescenzi, Catherine DeBrosse, Ravi P R Nanga, Matthew D Byrne, Guruprasad Krishnamoorthy, Kevin D'Aquilla, Hari Nath, Knashawn H Morales, Michiyo Iba, Hari Hariharan, Virginia M Y Lee, John A Detre, Ravinder Redd. Longitudinal imaging reveals subhippocampal dynamics in glutamate levels associated with histopathologic events in a mouse model of tauopathy and healthy mice. Hippocampus. vol 27. issue 3. 2018-01-09. PMID:27997993. |
we performed a longitudinal glucest imaging experiment paired with a cross-sectional study of histologic markers of tauopathy to determine whether (1) early glucest changes are associated with synapse loss before volume loss occurs in the hippocampus, and whether (2) subhippocampal dynamics in glucest are associated with histopathologic events related to glutamate alterations in tauopathy. |
2018-01-09 |
2023-08-13 |
mouse |
| Rachelle Crescenzi, Catherine DeBrosse, Ravi P R Nanga, Matthew D Byrne, Guruprasad Krishnamoorthy, Kevin D'Aquilla, Hari Nath, Knashawn H Morales, Michiyo Iba, Hari Hariharan, Virginia M Y Lee, John A Detre, Ravinder Redd. Longitudinal imaging reveals subhippocampal dynamics in glutamate levels associated with histopathologic events in a mouse model of tauopathy and healthy mice. Hippocampus. vol 27. issue 3. 2018-01-09. PMID:27997993. |
subregions of the hippocampus were analyzed (cornu ammonis ca1, ca3, dentate gyrus dg, and ventricle) in order to associate local mri-observable changes in glutamate with histological measures of glial cell proliferation (gfap), synapse density (synaptophysin, vglut1) and glutamate receptor (nmda-nr1) levels. |
2018-01-09 |
2023-08-13 |
mouse |
| Rachelle Crescenzi, Catherine DeBrosse, Ravi P R Nanga, Matthew D Byrne, Guruprasad Krishnamoorthy, Kevin D'Aquilla, Hari Nath, Knashawn H Morales, Michiyo Iba, Hari Hariharan, Virginia M Y Lee, John A Detre, Ravinder Redd. Longitudinal imaging reveals subhippocampal dynamics in glutamate levels associated with histopathologic events in a mouse model of tauopathy and healthy mice. Hippocampus. vol 27. issue 3. 2018-01-09. PMID:27997993. |
further, a gradient in glutamate levels was observed in vivo along hippocampal axes that became polarized as tauopathy progressed. |
2018-01-09 |
2023-08-13 |
mouse |
| Rachelle Crescenzi, Catherine DeBrosse, Ravi P R Nanga, Matthew D Byrne, Guruprasad Krishnamoorthy, Kevin D'Aquilla, Hari Nath, Knashawn H Morales, Michiyo Iba, Hari Hariharan, Virginia M Y Lee, John A Detre, Ravinder Redd. Longitudinal imaging reveals subhippocampal dynamics in glutamate levels associated with histopathologic events in a mouse model of tauopathy and healthy mice. Hippocampus. vol 27. issue 3. 2018-01-09. PMID:27997993. |
dynamics in hippocampal glutamate levels throughout lifetime were most closely correlated with combined changes in synaptophysin and gfap, indicating that glucest imaging may be a surrogate marker of glutamate concentration in glial cells and at the synaptic level. |
2018-01-09 |
2023-08-13 |
mouse |
| Monica Sathyanesan, Jacob M Haiar, Michael J Watt, Samuel S Newto. Restraint stress differentially regulates inflammation and glutamate receptor gene expression in the hippocampus of C57BL/6 and BALB/c mice. Stress (Amsterdam, Netherlands). vol 20. issue 2. 2018-01-09. PMID:28274152. |
restraint stress differentially regulates inflammation and glutamate receptor gene expression in the hippocampus of c57bl/6 and balb/c mice. |
2018-01-09 |
2023-08-13 |
mouse |
| Fernando da Silva Fiorin, Ana P de Oliveira Ferreira, Leandro R Ribeiro, Luiz F A Silva, Mauro R T de Castro, Luís R H da Silva, Mauro E P da Silveira, Ana P P Zemolin, Fernando Dobrachinski, Sara Marchesan de Oliveira, Jeferson L Franco, Félix A Soares, Ana F Furian, Mauro S Oliveira, Michele R Fighera, Luiz F Freire Roye. The Impact of Previous Physical Training on Redox Signaling after Traumatic Brain Injury in Rats: A Behavioral and Neurochemical Approach. Journal of neurotrauma. vol 33. issue 14. 2018-01-08. PMID:26651029. |
the hippocampal alterations in the redox status, which were characterized by dichlorofluorescein diacetate oxidation and superoxide dismutase (sod) activity inhibition, led to the impairment of protein function (na(+), k(+)-adenosine triphosphatase [atpase] activity inhibition) and glutamate uptake inhibition 24 h after neuronal injury. |
2018-01-08 |
2023-08-13 |
rat |
| Pirathiv Kugathasan, Jessica Waller, Ligia Westrich, Aicha Abdourahman, Joseph A Tamm, Alan L Pehrson, Elena Dale, Maria Gulinello, Connie Sanchez, Yan L. In vivo and in vitro effects of vortioxetine on molecules associated with neuroplasticity. Journal of psychopharmacology (Oxford, England). vol 31. issue 3. 2018-01-04. PMID:27678087. |
in rodent studies, vortioxetine increases glutamate neurotransmission, promotes dendritic branching and spine maturation, and elevates hippocampal expression of the activity-regulated cytoskeleton-associated protein (arc/arg3.1) at the transcript level. |
2018-01-04 |
2023-08-13 |
mouse |
| Sean D O'Shea, Imelda M Smith, Olive M McCabe, Michelle M Cronin, Dominic M Walsh, William T O'Conno. Intracerebroventricular Administration of Amyloid β-protein Oligomers Selectively Increases Dorsal Hippocampal Dialysate Glutamate Levels in the Awake Rat. Sensors (Basel, Switzerland). vol 8. issue 11. 2018-01-04. PMID:27873937. |
intracerebroventricular administration of amyloid β-protein oligomers selectively increases dorsal hippocampal dialysate glutamate levels in the awake rat. |
2018-01-04 |
2023-08-13 |
rat |
| Sean D O'Shea, Imelda M Smith, Olive M McCabe, Michelle M Cronin, Dominic M Walsh, William T O'Conno. Intracerebroventricular Administration of Amyloid β-protein Oligomers Selectively Increases Dorsal Hippocampal Dialysate Glutamate Levels in the Awake Rat. Sensors (Basel, Switzerland). vol 8. issue 11. 2018-01-04. PMID:27873937. |
microdialysis was employed to assess the effect of icv administration of aβ monomers and aβ oligomers on dialysate glutamate, aspartate and gaba levels in the dorsal hippocampus. |
2018-01-04 |
2023-08-13 |
rat |
| Muthiah Ramanathan, Khadar K Abdul, Antony Justi. Low dose of L-glutamic acid attenuated the neurological dysfunctions and excitotoxicity in bilateral common carotid artery occluded mice. Behavioural pharmacology. vol 27. issue 7. 2018-01-03. PMID:27564990. |
l-ga reduced glutamate levels in the cortex, striatum, and hippocampus at 72 h, whereas gaba levels were elevated in all three brain regions studied. |
2018-01-03 |
2023-08-13 |
mouse |
| Ulrich Frischknecht, Derik Hermann, Nuran Tunc-Skarka, Guo-Ying Wang, Markus Sack, Julia van Eijk, Traute Demirakca, Claudia Falfan-Melgoza, Bertram Krumm, Sandra Dieter, Rainer Spanagel, Falk Kiefer, Karl F Mann, Wolfgang H Sommer, Gabriele Ende, Wolfgang Weber-Fah. Negative Association Between MR-Spectroscopic Glutamate Markers and Gray Matter Volume After Alcohol Withdrawal in the Hippocampus: A Translational Study in Humans and Rats. Alcoholism, clinical and experimental research. vol 41. issue 2. 2018-01-03. PMID:28098946. |
negative association between mr-spectroscopic glutamate markers and gray matter volume after alcohol withdrawal in the hippocampus: a translational study in humans and rats. |
2018-01-03 |
2023-08-13 |
rat |
| Alberto Rubio-Casillas, Alonso Fernández-Guast. The dose makes the poison: from glutamate-mediated neurogenesis to neuronal atrophy and depression. Reviews in the neurosciences. vol 27. issue 6. 2018-01-02. PMID:27096778. |
additionally, it has been shown that chronic treatment with antidepressants having divergent mechanisms of action (including tricyclics, selective serotonin reuptake inhibitors, and ketamine) markedly reduced depolarization-evoked glutamate release in the hippocampus. |
2018-01-02 |
2023-08-13 |
Not clear |
| Olusoji A T Afuwape, Ege T Kavalal. Imaging Synaptic Vesicle Exocytosis-Endocytosis with pH-Sensitive Fluorescent Proteins. Methods in molecular biology (Clifton, N.J.). vol 1474. 2018-01-02. PMID:27515081. |
here, we describe the process of imaging synaptic vesicle endocytosis in response to extracellular stimulation in dissociated neuronal cultures of hippocampal neurons obtained from rats-also applicable to mice-using phluorin-tagged vesicular glutamate transporter-1 as a reporter. |
2018-01-02 |
2023-08-13 |
Not clear |
| Idrish Ali, Stephanie Boets, Pieter Janssens, Annemie Van Eetveldt, Halima Amhaoul, Xavier Langlois, Stefanie Dedeurwaerder. Metabotropic glutamate receptor 2/3 density and its relation to the hippocampal neuropathology in a model of temporal lobe epilepsy in rats. Epilepsy research. vol 127. 2018-01-02. PMID:27565411. |
metabotropic glutamate receptor 2/3 density and its relation to the hippocampal neuropathology in a model of temporal lobe epilepsy in rats. |
2018-01-02 |
2023-08-13 |
rat |
| João T Costa, Miranda Mele, Márcio S Baptista, João R Gomes, Karsten Ruscher, Rui J Nobre, Luís Pereira de Almeida, Tadeusz Wieloch, Carlos B Duart. Gephyrin Cleavage in In Vitro Brain Ischemia Decreases GABAA Receptor Clustering and Contributes to Neuronal Death. Molecular neurobiology. vol 53. issue 6. 2017-12-29. PMID:26093381. |
we found that gephyrin is cleaved by calpains following excitotoxic stimulation of hippocampal neurons with glutamate, as well as after intrahippocampal injection of kainate, giving rise to a stable cleavage product. |
2017-12-29 |
2023-08-13 |
mouse |
| Isabella Panaccione, Luisa Iacovelli, Luigi di Nuzzo, Francesca Nardecchia, Gianluca Mauro, Delfina Janiri, Antonio De Blasi, Gabriele Sani, Ferdinando Nicoletti, Rosamaria Orland. Paradoxical sleep deprivation in rats causes a selective reduction in the expression of type-2 metabotropic glutamate receptors in the hippocampus. Pharmacological research. vol 117. 2017-12-27. PMID:27890550. |
paradoxical sleep deprivation in rats causes a selective reduction in the expression of type-2 metabotropic glutamate receptors in the hippocampus. |
2017-12-27 |
2023-08-13 |
rat |
| Isabella Panaccione, Luisa Iacovelli, Luigi di Nuzzo, Francesca Nardecchia, Gianluca Mauro, Delfina Janiri, Antonio De Blasi, Gabriele Sani, Ferdinando Nicoletti, Rosamaria Orland. Paradoxical sleep deprivation in rats causes a selective reduction in the expression of type-2 metabotropic glutamate receptors in the hippocampus. Pharmacological research. vol 117. 2017-12-27. PMID:27890550. |
sleep deprived rats showed a substantial reduction in type-2 metabotropic glutamate (mglu2) receptors mrna and protein levels in the hippocampus, but not in the prefrontal cortex or corpus striatum, as compared to both groups of control rats. |
2017-12-27 |
2023-08-13 |
rat |
| Erica Zamberletti, Marina Gabaglio, Massimo Grilli, Pamela Prini, Alberto Catanese, Anna Pittaluga, Mario Marchi, Tiziana Rubino, Daniela Parolar. Long-term hippocampal glutamate synapse and astrocyte dysfunctions underlying the altered phenotype induced by adolescent THC treatment in male rats. Pharmacological research. vol 111. 2017-12-25. PMID:27422357. |
long-term hippocampal glutamate synapse and astrocyte dysfunctions underlying the altered phenotype induced by adolescent thc treatment in male rats. |
2017-12-25 |
2023-08-13 |
rat |
| Giulia Treccani, Kristian Gaarn du Jardin, Gregers Wegener, Heidi Kaastrup Mülle. Differential expression of postsynaptic NMDA and AMPA receptor subunits in the hippocampus and prefrontal cortex of the flinders sensitive line rat model of depression. Synapse (New York, N.Y.). vol 70. issue 11. 2017-12-22. PMID:27262028. |
to gain insight into how signaling through glutamate receptors may be altered in the fsl rats, we investigated the expression and phosphorylation of ampa and nmda receptor subunits in an enriched postsynaptic fraction of the hippocampus and prefrontal cortex. |
2017-12-22 |
2023-08-13 |
rat |
| Giulia Treccani, Kristian Gaarn du Jardin, Gregers Wegener, Heidi Kaastrup Mülle. Differential expression of postsynaptic NMDA and AMPA receptor subunits in the hippocampus and prefrontal cortex of the flinders sensitive line rat model of depression. Synapse (New York, N.Y.). vol 70. issue 11. 2017-12-22. PMID:27262028. |
these results support altered expression of postsynaptic glutamate receptors in the hippocampus of fsl rats, which may contribute to the depressive-like phenotype of these rats. |
2017-12-22 |
2023-08-13 |
rat |