| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| João A Amorim, Paula M Canas, Angelo R Tomé, Anabela P Rolo, Paula Agostinho, Carlos M Palmeira, Rodrigo A Cunh. Mitochondria in Excitatory and Inhibitory Synapses have Similar Susceptibility to Amyloid-β Peptides Modeling Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 60. issue 2. 2018-04-09. PMID:28869472. |
the direct exposure of hippocampal synaptosomes to aβ1-42 (500 nm) similarly decreased mitochondrial membrane potential (tmrm+ fluorescence) and increased mitochondria-derived oxygen radicals (mitotraker®red-cm-h2xros fluorescence) in individual glutamatergic (vesicular glutamate transporter-immunopositive) and gabaergic (vesicular gaba transporter-immunopositive) synaptosomes. |
2018-04-09 |
2023-08-13 |
rat |
| Iñigo Murga, Virginia Guillen, José-Vicente Lafuent. Cerebral magnetic resonance changes associated with fibromyalgia syndrome. Medicina clinica. vol 148. issue 11. 2018-04-04. PMID:28450073. |
modifications in gray and white matter volume, as well as in levels of n-acetylaspartate, choline or glutamate, among other metabolites, have been observed in the hippocampus, insula, prefrontal and cingular cortex. |
2018-04-04 |
2023-08-13 |
Not clear |
| Atieh Arzhang, Mahmoud Elahdadi Salmani, Taghi Lashkarbolouki, Iran Goudarz. Posterior hypothalamus glutamate infusion decreases pentylenetetrazol-induced seizures of male rats through hippocampal histamine increase. Pharmacology, biochemistry, and behavior. vol 158. 2018-03-26. PMID:28495313. |
posterior hypothalamus glutamate infusion decreases pentylenetetrazol-induced seizures of male rats through hippocampal histamine increase. |
2018-03-26 |
2023-08-13 |
rat |
| Atieh Arzhang, Mahmoud Elahdadi Salmani, Taghi Lashkarbolouki, Iran Goudarz. Posterior hypothalamus glutamate infusion decreases pentylenetetrazol-induced seizures of male rats through hippocampal histamine increase. Pharmacology, biochemistry, and behavior. vol 158. 2018-03-26. PMID:28495313. |
histamine originates from neurons of the posterior hypothalamus (ph) and can mediate anticonvulsant properties, but the effect of local ph glutamate on hippocampal histamine content is unknown. |
2018-03-26 |
2023-08-13 |
rat |
| Atieh Arzhang, Mahmoud Elahdadi Salmani, Taghi Lashkarbolouki, Iran Goudarz. Posterior hypothalamus glutamate infusion decreases pentylenetetrazol-induced seizures of male rats through hippocampal histamine increase. Pharmacology, biochemistry, and behavior. vol 158. 2018-03-26. PMID:28495313. |
therefore, in this study, the effect of ph glutamate and the involvement of hippocampal histamine in pentylenetetrazol (ptz) induced seizure activity was studied. |
2018-03-26 |
2023-08-13 |
rat |
| Wei Bu, Wen-Qing Zhao, Wen-Ling Li, Chang-Zheng Dong, Zhe Zhang, Qi-Jun L. Neuropeptide Y suppresses epileptiform discharges by regulating AMPA receptor GluR2 subunit in rat hippocampal neurons. Molecular medicine reports. vol 16. issue 1. 2018-03-26. PMID:28498410. |
the present study aimed to investigate the effects of neuropeptide y (npy) on the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor glutamate receptor 2 (glur2) subunit in epileptiform discharge hippocampal neurons. |
2018-03-26 |
2023-08-13 |
rat |
| Ding Luo, Rui Ma, Yanan Wu, Xuechun Zhang, Yue Liu, Lin Wang, Wenbin F. Mechanism Underlying Acupuncture-Ameliorated Depressive Behaviors by Enhancing Glial Glutamate Transporter in Chronic Unpredictable Mild Stress (CUMS) Rats. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2018-03-26. PMID:28644824. |
the amelioration of depressive behavioral actions was consistent with increasing number of positive cells, protein, and mrna expression of glial glutamate transporter eaat2 in the hippocampus and pfc. |
2018-03-26 |
2023-08-13 |
rat |
| Ding Luo, Rui Ma, Yanan Wu, Xuechun Zhang, Yue Liu, Lin Wang, Wenbin F. Mechanism Underlying Acupuncture-Ameliorated Depressive Behaviors by Enhancing Glial Glutamate Transporter in Chronic Unpredictable Mild Stress (CUMS) Rats. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2018-03-26. PMID:28644824. |
enhance glial glutamate transporter eaat2 in the hippocampus and pfc is a mechanism underlying the antidepressant effect of acupuncture. |
2018-03-26 |
2023-08-13 |
rat |
| Isabelle M Rosso, David J Crowley, Marisa M Silveri, Scott L Rauch, J Eric Jense. Hippocampus Glutamate and N-Acetyl Aspartate Markers of Excitotoxic Neuronal Compromise in Posttraumatic Stress Disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 8. 2018-03-23. PMID:28195577. |
hippocampus glutamate and n-acetyl aspartate markers of excitotoxic neuronal compromise in posttraumatic stress disorder. |
2018-03-23 |
2023-08-13 |
human |
| Isabelle M Rosso, David J Crowley, Marisa M Silveri, Scott L Rauch, J Eric Jense. Hippocampus Glutamate and N-Acetyl Aspartate Markers of Excitotoxic Neuronal Compromise in Posttraumatic Stress Disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 8. 2018-03-23. PMID:28195577. |
hippocampus atrophy is implicated in posttraumatic stress disorder (ptsd), and may partly reflect stress-induced glutamate excitotoxicity that culminates in neuron injury and manifests as re-experiencing symptoms and other memory abnormalities. |
2018-03-23 |
2023-08-13 |
human |
| Isabelle M Rosso, David J Crowley, Marisa M Silveri, Scott L Rauch, J Eric Jense. Hippocampus Glutamate and N-Acetyl Aspartate Markers of Excitotoxic Neuronal Compromise in Posttraumatic Stress Disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 8. 2018-03-23. PMID:28195577. |
this study used high-field proton magnetic resonance spectroscopy (mrs) to determine whether ptsd is associated with lower hippocampus levels of the neuron marker n-acetyl aspartate (naa), along with higher levels of glutamate (glu) and glu/naa. |
2018-03-23 |
2023-08-13 |
human |
| Isabelle M Rosso, David J Crowley, Marisa M Silveri, Scott L Rauch, J Eric Jense. Hippocampus Glutamate and N-Acetyl Aspartate Markers of Excitotoxic Neuronal Compromise in Posttraumatic Stress Disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 8. 2018-03-23. PMID:28195577. |
their robust associations with re-experiencing symptoms affirm that mrs indices of hippocampus neuron integrity and glutamate metabolism may reflect biomarkers of clinically significant disease variation in ptsd. |
2018-03-23 |
2023-08-13 |
human |
| Jeffrey A Stanley, Ashley Burgess, Dalal Khatib, Karthik Ramaseshan, Muzamil Arshad, Helen Wu, Vaibhav A Diwadka. Functional dynamics of hippocampal glutamate during associative learning assessed with in vivo NeuroImage. vol 153. 2018-03-22. PMID:28363835. |
functional dynamics of hippocampal glutamate during associative learning assessed with in vivo fmri has provided vibrant characterization of regional and network responses associated with associative learning and memory; however, their relationship to functional neurochemistry is unclear. |
2018-03-22 |
2023-08-13 |
Not clear |
| Damian M Cummings, Tiffanie A Benway, Hinze Ho, Angelo Tedoldi, Monica M Fernandes Freitas, Lion Shahab, Christina E Murray, Angela Richard-Loendt, Sebastian Brandner, Tammaryn Lashley, Dervis A Salih, Frances A Edward. Neuronal and Peripheral Pentraxins Modify Glutamate Release and may Interact in Blood-Brain Barrier Failure. Cerebral cortex (New York, N.Y. : 1991). vol 27. issue 6. 2018-03-19. PMID:28334103. |
here, we confirm the presence of nptx1 around plaques in postmortem alzheimer's disease brain and report that acutely applied human nptx1 increases paired-pulse ratio at mouse ca3-ca1 hippocampal synapses, indicating a decrease in glutamate release. |
2018-03-19 |
2023-08-13 |
mouse |
| Mengwen Qi, Chunfeng Wu, Zhouqing Wang, Li Zhou, Chen Men, Yimei Du, Songming Huang, Lei Chen, Ling Che. Transient Receptor Potential Vanilloid 4 Activation-Induced Increase in Glycine-Activated Current in Mouse Hippocampal Pyramidal Neurons. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 45. issue 3. 2018-03-19. PMID:29439248. |
glycine plays an important role in regulating hippocampal inhibitory/ excitatory neurotransmission through activating glycine receptors (glyrs) and acting as a co-agonist of n-methyl-d-aspartate-type glutamate receptors. |
2018-03-19 |
2023-08-13 |
mouse |
| Fabiana K Ludka, Tharine Dal-Cim, Luisa Bandeira Binder, Leandra Celso Constantino, Caio Massari, Carla I Tasc. Atorvastatin and Fluoxetine Prevent Oxidative Stress and Mitochondrial Dysfunction Evoked by Glutamate Toxicity in Hippocampal Slices. Molecular neurobiology. vol 54. issue 5. 2018-03-09. PMID:27052955. |
atorvastatin and fluoxetine prevent oxidative stress and mitochondrial dysfunction evoked by glutamate toxicity in hippocampal slices. |
2018-03-09 |
2023-08-13 |
mouse |
| Fabiana K Ludka, Tharine Dal-Cim, Luisa Bandeira Binder, Leandra Celso Constantino, Caio Massari, Carla I Tasc. Atorvastatin and Fluoxetine Prevent Oxidative Stress and Mitochondrial Dysfunction Evoked by Glutamate Toxicity in Hippocampal Slices. Molecular neurobiology. vol 54. issue 5. 2018-03-09. PMID:27052955. |
in this study, a comparison of the mechanisms involved in the putative neuroprotective effect of a repetitive atorvastatin or fluoxetine treatment against glutamate toxicity in hippocampal slices was performed. |
2018-03-09 |
2023-08-13 |
mouse |
| Fabiana K Ludka, Tharine Dal-Cim, Luisa Bandeira Binder, Leandra Celso Constantino, Caio Massari, Carla I Tasc. Atorvastatin and Fluoxetine Prevent Oxidative Stress and Mitochondrial Dysfunction Evoked by Glutamate Toxicity in Hippocampal Slices. Molecular neurobiology. vol 54. issue 5. 2018-03-09. PMID:27052955. |
on the eighth day, animals were killed and hippocampal slices were obtained and subjected to an in vitro protocol of glutamate toxicity. |
2018-03-09 |
2023-08-13 |
mouse |
| Fabiana K Ludka, Tharine Dal-Cim, Luisa Bandeira Binder, Leandra Celso Constantino, Caio Massari, Carla I Tasc. Atorvastatin and Fluoxetine Prevent Oxidative Stress and Mitochondrial Dysfunction Evoked by Glutamate Toxicity in Hippocampal Slices. Molecular neurobiology. vol 54. issue 5. 2018-03-09. PMID:27052955. |
an acute treatment of atorvastatin or fluoxetine was not neuroprotective; however, the repeated atorvastatin or fluoxetine treatment prevented the decrease in cellular viability induced by glutamate in hippocampal slices. |
2018-03-09 |
2023-08-13 |
mouse |
| Fabiana K Ludka, Tharine Dal-Cim, Luisa Bandeira Binder, Leandra Celso Constantino, Caio Massari, Carla I Tasc. Atorvastatin and Fluoxetine Prevent Oxidative Stress and Mitochondrial Dysfunction Evoked by Glutamate Toxicity in Hippocampal Slices. Molecular neurobiology. vol 54. issue 5. 2018-03-09. PMID:27052955. |
atorvastatin or fluoxetine treatment was effective in protecting mice hippocampal slices from glutamate toxicity by preventing the oxidative stress and mitochondrial dysfunction. |
2018-03-09 |
2023-08-13 |
mouse |