| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiaojiao Song, Ming Chen, Yi Dong, Bin Lai, Ping Zhen. Chronic morphine selectively sensitizes the effect of D1 receptor agonist on presynaptic glutamate release in basolateral amygdala neurons that project to prelimbic cortex. Neuropharmacology. vol 133. 2018-11-05. PMID:29427651. |
using retrogradely labelling technique combined with whole-cell patch-clamp methods, our results showed that (1) chronic morphine sensitized the effect of d1 receptor agonist on presynaptic glutamate release in bla neurons that projected to the prelimbic cortex (prl), but had no influence on that in bla neurons that projected to the nucleus accumbens (nac) or the ca1 of the hippocampus; (2) chronic morphine sensitized the effect of d1 receptor agonist on action potential firing in bla neurons that projected to the prl, but without affecting the intrinsic excitability and the sensitivity of postsynaptic glutamate receptors to glutamate in bla neurons that projected to the prl. |
2018-11-05 |
2023-08-13 |
Not clear |
| Mandy Busse, Vanessa Hettler, Victoria Fischer, Christian Mawrin, Roland Hartig, Henrik Dobrowolny, Bernhard Bogerts, Thomas Frodl, Stefan Buss. Increased quinolinic acid in peripheral mononuclear cells in Alzheimer's dementia. European archives of psychiatry and clinical neuroscience. vol 268. issue 5. 2018-10-26. PMID:28386767. |
although only little is known about the function of activated macrophages and microglia in ad, one important mechanism involves the expression of quinolinic acid (quin), an endogenous n-methyl-d-aspartate glutamate receptor (nmda-r) agonist which mediates excitotoxicity especially in the hippocampus. |
2018-10-26 |
2023-08-13 |
human |
| Sigrid Ottestad-Hansen, Qiu Xiang Hu, Virgine Veronique Follin-Arbelet, Eduard Bentea, Hideyo Sato, Ann Massie, Yun Zhou, Niels Christian Danbol. The cystine-glutamate exchanger (xCT, Slc7a11) is expressed in significant concentrations in a subpopulation of astrocytes in the mouse brain. Glia. vol 66. issue 5. 2018-10-25. PMID:29350434. |
the concentration of xct protein in hippocampus was compared with that of the eaat3 glutamate transporter by immunoblotting using a chimeric xct-eaat3 protein to normalize xct and eaat3 labeling intensities. |
2018-10-25 |
2023-08-13 |
mouse |
| Edward J Goetzl, Erin L Abner, Gregory A Jicha, Dimitrios Kapogiannis, Janice B Schwart. Declining levels of functionally specialized synaptic proteins in plasma neuronal exosomes with progression of Alzheimer's disease. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 32. issue 2. 2018-10-23. PMID:29025866. |
interactions of the presynaptic proteins, neuronal pentraxin 2 (nptx2) and neurexin 2α (nrxn2α), with their respective postsynaptic functional partners, glua4-containing glutamate (ampa4) receptor and neuroligin 1 (nlgn1), enhance excitatory synaptic activity in some areas of the hippocampus and cerebral cortex. |
2018-10-23 |
2023-08-13 |
human |
| Aisa N Chepkova, Olga A Sergeeva, Boris Görg, Helmut L Haas, Nikolaj Klöcker, Dieter Häussinge. Impaired novelty acquisition and synaptic plasticity in congenital hyperammonemia caused by hepatic glutamine synthetase deficiency. Scientific reports. vol 7. 2018-10-18. PMID:28067279. |
corticostriatal but not hippocampal slices from lgs-ko brains demonstrated also significant alterations in long-lasting effects evoked by pharmacological activation of glutamate receptors. |
2018-10-18 |
2023-08-13 |
mouse |
| Matteo Dal Ben, Cristina Bottin, Fabrizio Zanconati, Claudio Tiribelli, Silvia Gazzi. Evaluation of region selective bilirubin-induced brain damage as a basis for a pharmacological treatment. Scientific reports. vol 7. 2018-10-15. PMID:28102362. |
glutamate excitotoxicity was appreciable in only the hippocampus and inferior colliculus. |
2018-10-15 |
2023-08-13 |
rat |
| Yu Shang, Qiang Xue, Pei-Fei Gu, Yue Li, Guang-Jie Ga. [Effect of dexmedetomidine on the changes of EAA and the expression of NMDA NR1 protein in hippocampus in global cerebral ischemia/reperfusion rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 32. issue 2. 2018-10-15. PMID:29931869. |
to observe the effects of dexmedetomidine (dex) on glutamate (glu), aspartic acid (asp) release and nmdar1 expression in hippocampus in global cerebral ischemia/reperfusion rats, and investigate the protective effect and the related mechanism of neurotransmitters. |
2018-10-15 |
2023-08-13 |
rat |
| Qinghua Zhang, Yang Liu, Hui Wang, Li Ma, Hechun Xia, Jianguo Niu, Tao Sun, Li Zhan. The preventive effects of taurine on neural tube defects through the Wnt/PCP-Jnk-dependent pathway. Amino acids. vol 49. issue 9. 2018-10-10. PMID:28718066. |
ht-22 cells (a hippocampal neuron cell line) were divided into a control group, a glutamate-induced apoptosis group, and glutamate (4.0 mmol/l) plus low-dose taurine (l; 0.5 mmol/l) and high-dose taurine (h; 2.0 mmol/l) groups. |
2018-10-10 |
2023-08-13 |
mouse |
| Manila Loi, Ratna Angela Sarabdjitsingh, Andromachi Tsouli, Stephanie Trinh, Marit Arp, Harmen J Krugers, Henk Karst, Ruud van den Bos, Marian Joël. Transient Prepubertal Mifepristone Treatment Normalizes Deficits in Contextual Memory and Neuronal Activity of Adult Male Rats Exposed to Maternal Deprivation. eNeuro. vol 4. issue 5. 2018-09-20. PMID:29098176. |
follow-up electrophysiological recordings measuring spontaneous glutamate transmission showed reduced frequency of miniature postsynaptic excitatory currents in adult ca1 dorsal hippocampal and enhanced frequency in dorsomedial striatal neurons from md versus nomd rats, which was not seen in mif-treated rats. |
2018-09-20 |
2023-08-13 |
rat |
| Nurgul Aytan, Ji-Kyung Choi, Isabel Carreras, Leah Crabtree, Brian Nguyen, Margaret Lehar, Jan Krzysztof Blusztajn, Bruce G Jenkins, Alpaslan Dedeogl. Protective effects of 7,8-dihydroxyflavone on neuropathological and neurochemical changes in a mouse model of Alzheimer's disease. European journal of pharmacology. vol 828. 2018-09-19. PMID:29510124. |
in addition 7,8-dhf treatment protected against hippocampal increase in the level of choline-containing compounds and glutamate loss, but had no significant impact on hippocampal neurogenesis. |
2018-09-19 |
2023-08-13 |
mouse |
| Claudia Rebosio, Matilde Balbi, Mario Passalacqua, Roberta Ricciarelli, Ernesto Fedel. Presynaptic GLP-1 receptors enhance the depolarization-evoked release of glutamate and GABA in the mouse cortex and hippocampus. BioFactors (Oxford, England). vol 44. issue 2. 2018-09-13. PMID:29265673. |
presynaptic glp-1 receptors enhance the depolarization-evoked release of glutamate and gaba in the mouse cortex and hippocampus. |
2018-09-13 |
2023-08-13 |
mouse |
| Hyo Young Jung, Dae Young Yoo, Joon Ha Park, Jong Whi Kim, Jin Young Chung, Dae Won Kim, Moo-Ho Won, Yeo Sung Yoon, In Koo Hwan. Age-dependent changes in vesicular glutamate transporter 1 and 2 expression in the gerbil hippocampus. Molecular medicine reports. vol 17. issue 5. 2018-09-13. PMID:29532891. |
age-dependent changes in vesicular glutamate transporter 1 and 2 expression in the gerbil hippocampus. |
2018-09-13 |
2023-08-13 |
Not clear |
| Simon Chamberland, Yulia Timofeeva, Alesya Evstratova, Kirill Volynski, Katalin Tót. Action potential counting at giant mossy fiber terminals gates information transfer in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 28. 2018-09-10. PMID:29946034. |
hippocampal mossy fibers have long been recognized as conditional detonators owing to prominent short-term facilitation of glutamate release displayed during granule cell burst firing. |
2018-09-10 |
2023-08-13 |
Not clear |
| Wucheng Tao, Javier Díaz-Alonso, Nengyin Sheng, Roger A Nicol. Postsynaptic δ1 glutamate receptor assembles and maintains hippocampal synapses via Cbln2 and neurexin. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 23. 2018-09-04. PMID:29784783. |
postsynaptic δ1 glutamate receptor assembles and maintains hippocampal synapses via cbln2 and neurexin. |
2018-09-04 |
2023-08-13 |
mouse |
| Ya-Bo Feng, You-Ting Lin, Yu-Xiang Han, Yue-Jiu Pang, Jing-Jing Xu, Yuan Xue, Hong Ya. 2R,4R-APDC, a Metabotropic Glutamate Receptor Agonist, Reduced Neuronal Apoptosis by Upregulating MicroRNA-128 in a Rat Model After Seizures. Neurochemical research. vol 43. issue 3. 2018-08-30. PMID:29497903. |
this study aimed to study the protective effect of (2r,4r)-4-aminopyrrolidine-2,4-dicarboxylate (2r,4r-apdc), a selective metabotropic glutamate receptor agonist, against hippocampal neuronal apoptosis induced by seizures in a rat model of pilocarpine-induced epilepsy. |
2018-08-30 |
2023-08-13 |
rat |
| Asuka Ito, Mostofa Jamal, Kiyoshi Ameno, Naoko Tanaka, Ayaka Takakura, Takanori Miki, Hiroshi Kinoshit. Perfusion with carbon monoxide does not affect extracellular glutamate in dialysates of the hippocampus of freely moving mice. Drug and chemical toxicology. vol 41. issue 2. 2018-08-27. PMID:28866965. |
perfusion with carbon monoxide does not affect extracellular glutamate in dialysates of the hippocampus of freely moving mice. |
2018-08-27 |
2023-08-13 |
mouse |
| Asuka Ito, Mostofa Jamal, Kiyoshi Ameno, Naoko Tanaka, Ayaka Takakura, Takanori Miki, Hiroshi Kinoshit. Perfusion with carbon monoxide does not affect extracellular glutamate in dialysates of the hippocampus of freely moving mice. Drug and chemical toxicology. vol 41. issue 2. 2018-08-27. PMID:28866965. |
thus, the present study was aimed at investigating the local effect of co on the glutamate level in the hippocampus of mice using in vivo reverse microdialysis. |
2018-08-27 |
2023-08-13 |
mouse |
| Asuka Ito, Mostofa Jamal, Kiyoshi Ameno, Naoko Tanaka, Ayaka Takakura, Takanori Miki, Hiroshi Kinoshit. Perfusion with carbon monoxide does not affect extracellular glutamate in dialysates of the hippocampus of freely moving mice. Drug and chemical toxicology. vol 41. issue 2. 2018-08-27. PMID:28866965. |
this finding does not support a local co rise as the cause of the increased glutamate level in the hippocampus of mice. |
2018-08-27 |
2023-08-13 |
mouse |
| Guishan Zhang, Qi Li, Wenhua Gao, Shaowen Liu, Renhua Wu, Zhiwei Shen, Wenhua Liu, Yaowen Che. Copper chloride dose-dependently alters spatial learning and memory, and glutamate levels, in the hippocampus of rats. Molecular medicine reports. vol 17. issue 3. 2018-08-15. PMID:29257305. |
copper chloride dose-dependently alters spatial learning and memory, and glutamate levels, in the hippocampus of rats. |
2018-08-15 |
2023-08-13 |
rat |
| Yiqing Huang, Xixia Liu, Yuhan Liao, Yayun Liao, Donghua Zou, Xing Wei, Qi Huang, Yuan W. Role of miR-34c in the cognitive function of epileptic rats induced by pentylenetetrazol. Molecular medicine reports. vol 17. issue 3. 2018-08-15. PMID:29344671. |
glutamate receptor ionotropic n‑methyl‑d‑aspartate (nmda) 2b (nr2b), phosphorylated (p)‑reduced nicotinamide‑adenine dinucleotide phosphate‑dependent diflavin oxidoreductase 1 (nr1) and p‑glutamate receptor 1 (glur1) protein expression was detected in the hippocampus using western blotting. |
2018-08-15 |
2023-08-13 |
rat |