| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhi-Hong Wang, Mei-Chin Mong, Ya-Chen Yang, Mei-Chin Yi. Asiatic acid and maslinic acid attenuated kainic acid-induced seizure through decreasing hippocampal inflammatory and oxidative stress. Epilepsy research. vol 139. 2018-12-11. PMID:29156327. |
seizure is a neurological disorder including hippocampal oxidative and inflammatory stress, and glutamate toxicity. |
2018-12-11 |
2023-08-13 |
mouse |
| Fabian Dammann, Timo Kirschstein, Xiati Guli, Steffen Müller, Katrin Porath, Marco Rohde, Tursonjan Tokay, Rüdiger Köhlin. Bidirectional shift of group III metabotropic glutamate receptor-mediated synaptic depression in the epileptic hippocampus. Epilepsy research. vol 139. 2018-12-11. PMID:29224956. |
bidirectional shift of group iii metabotropic glutamate receptor-mediated synaptic depression in the epileptic hippocampus. |
2018-12-11 |
2023-08-13 |
rat |
| Yuqing Zhang, Shuai Yuan, Juncai Pu, Lining Yang, Xinyu Zhou, Lanxiang Liu, Xiaofeng Jiang, Hanping Zhang, Teng Teng, Lu Tian, Peng Xi. Integrated Metabolomics and Proteomics Analysis of Hippocampus in a Rat Model of Depression. Neuroscience. vol 371. 2018-12-11. PMID:29237567. |
the integrated analyses revealed four major changes in the hippocampus of cums rats: (1) impairment in amino acid metabolism and protein synthesis/degradation; (2) dysregulation of glutamate and glycine metabolism and their transport/catabolism related proteins; (3) disturbances in fatty acid and glycerophospholipid metabolism accompanied by alterations in the corresponding metabolic enzymes; (4) abnormal expression of synapse-associated proteins. |
2018-12-11 |
2023-08-13 |
rat |
| Adam Hamed, Miron Bartosz Kurs. Inter-individual differences in serotonin and glutamate co-transmission reflect differentiation in context-induced conditioned 50-kHz USVs response after morphine withdrawal. Brain structure & function. vol 223. issue 7. 2018-12-11. PMID:29774428. |
moreover, 5-ht concentration in amygdala is bound up with glutamate level in this structure as well as in hippocampus. |
2018-12-11 |
2023-08-13 |
rat |
| Adam Hamed, Miron Bartosz Kurs. Inter-individual differences in serotonin and glutamate co-transmission reflect differentiation in context-induced conditioned 50-kHz USVs response after morphine withdrawal. Brain structure & function. vol 223. issue 7. 2018-12-11. PMID:29774428. |
all-to-all-analysis indicate that concentration of glutamate in hippocampus is proportional to glutamate in vta and gaba concentration in the hippocampus. |
2018-12-11 |
2023-08-13 |
rat |
| Izuki Amano, Yusuke Takatsuru, Miski Aghnia Khairinisa, Michifumi Kokubo, Asahi Haijima, Noriyuki Koibuch. Effects of Mild Perinatal Hypothyroidism on Cognitive Function of Adult Male Offspring. Endocrinology. vol 159. issue 4. 2018-11-27. PMID:29522169. |
we next measured the concentration of neurotransmitters (glutamate, γ-aminobutyric acid, and glycine) in the hippocampus using in vivo microdialysis during olt. |
2018-11-27 |
2023-08-13 |
mouse |
| Daiying Zuo, Yumiao Liu, Zi Liu, Jiahui Cui, Xuejiao Zhou, Yang Liu, Zengqiang Li, Yingliang W. Alcohol aggravates ketamine-induced behavioral, morphological and neurochemical alterations in adolescent rats: The involvement of CREB-related pathways. Behavioural brain research. vol 349. 2018-11-26. PMID:29738804. |
this potentiation was associated with the enhancement by alcohol of ketamine-induced glutamate (glu) and dopamine (da) release in the cortex and hippocampus. |
2018-11-26 |
2023-08-13 |
rat |
| Jin-Seok Lee, Won-Yong Kim, Yoo-Jin Jeon, Sam-Keun Lee, Chang-Gue So. Aquilariae Lignum extract attenuates glutamate-induced neuroexcitotoxicity in HT22 hippocampal cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 106. 2018-11-26. PMID:30119168. |
we investigated the anti-excitotoxic effects and associated working mechanisms of 30% ethanol extract of aquilariae lignum (ale) against hippocampal neuronal death by glutamate. |
2018-11-26 |
2023-08-13 |
Not clear |
| Li Xiong, Hao Liyue, Zeng Fancai, Li Maoting, Li Ya, He Ting, Yang Zhen, Zhu Shanshan, Gu Wenwen, Tang Ya. Effect of decabrominated diphenyl ether exposure on spatial learning and memory, the expression and phosphorylation of hippocampal glutamate receptor subunits in adult Sprague-Dawley rats. The Journal of toxicological sciences. vol 43. issue 11. 2018-11-26. PMID:30404998. |
effect of decabrominated diphenyl ether exposure on spatial learning and memory, the expression and phosphorylation of hippocampal glutamate receptor subunits in adult sprague-dawley rats. |
2018-11-26 |
2023-08-13 |
rat |
| Li Xiong, Hao Liyue, Zeng Fancai, Li Maoting, Li Ya, He Ting, Yang Zhen, Zhu Shanshan, Gu Wenwen, Tang Ya. Effect of decabrominated diphenyl ether exposure on spatial learning and memory, the expression and phosphorylation of hippocampal glutamate receptor subunits in adult Sprague-Dawley rats. The Journal of toxicological sciences. vol 43. issue 11. 2018-11-26. PMID:30404998. |
the expression of hippocampal glutamate receptor subunits nr1, nr2b and glur1, the phosphorylation of nr2b subunit at ser1301 (p-nr2b ser1303) and glur1 subunit at ser831 (p-glur1 ser831) were all decreased, and the phosphorylation ratio of nr2b revealed an increasing trend after bde 209 exposure. |
2018-11-26 |
2023-08-13 |
rat |
| Benneth Ben-Azu, Adegbuyi Oladele Aderibigbe, Aya-Ebi Okubo Eneni, Abayomi Mayowa Ajayi, Solomon Umukoro, Ezekiel O Iwalew. Morin Attenuates Neurochemical Changes and Increased Oxidative/Nitrergic Stress in Brains of Mice Exposed to Ketamine: Prevention and Reversal of Schizophrenia-Like Symptoms. Neurochemical research. vol 43. issue 9. 2018-11-21. PMID:29956036. |
thereafter, the brain levels of dopamine, glutamate, 5-hydroxytryptamine and acetyl-cholinesterase, as well as biomarkers of oxidative/nitrergic stress were measured in the striatum, prefrontal-cortex (pfc) and hippocampus (hc). |
2018-11-21 |
2023-08-13 |
mouse |
| Chunhua Liu, Shuang Hao, Minghui Zhu, Yingxuan Wang, Tao Zhang, Zhuo Yan. Maternal Separation Induces Different Autophagic Responses in the Hippocampus and Prefrontal Cortex of Adult Rats. Neuroscience. vol 374. 2018-11-20. PMID:29391188. |
compared with the con group, the glutamate level was obviously increased in the hippocampus (hp) and prefrontal cortex (pfc) of rats in the ms group. |
2018-11-20 |
2023-08-13 |
rat |
| Atiah H Almalki, Sujan C Das, Fahad S Alshehri, Yusuf S Althobaiti, Youssef Sar. Effects of sequential ethanol exposure and repeated high-dose methamphetamine on striatal and hippocampal dopamine, serotonin and glutamate tissue content in Wistar rats. Neuroscience letters. vol 665. 2018-11-13. PMID:29174641. |
effects of sequential ethanol exposure and repeated high-dose methamphetamine on striatal and hippocampal dopamine, serotonin and glutamate tissue content in wistar rats. |
2018-11-13 |
2023-08-13 |
rat |
| Atiah H Almalki, Sujan C Das, Fahad S Alshehri, Yusuf S Althobaiti, Youssef Sar. Effects of sequential ethanol exposure and repeated high-dose methamphetamine on striatal and hippocampal dopamine, serotonin and glutamate tissue content in Wistar rats. Neuroscience letters. vol 665. 2018-11-13. PMID:29174641. |
however, little is known about the effect of sequential exposure to ethanol and meth on glutamate, dopamine and serotonin tissue content in striatum and hippocampus. |
2018-11-13 |
2023-08-13 |
rat |
| Amanda M Sweeney, Kelsey E Fleming, John P McCauley, Marvin F Rodriguez, Elliot T Martin, Alioscka A Sousa, Richard D Leapman, Annalisa Scimem. PAR1 activation induces rapid changes in glutamate uptake and astrocyte morphology. Scientific reports. vol 7. 2018-11-08. PMID:28256580. |
here we show that, in the mouse hippocampus, par1 activation induces a rapid structural re-organization of the neuropil surrounding glutamatergic synapses, which is associated with faster clearance of synaptically-released glutamate from the extracellular space. |
2018-11-08 |
2023-08-13 |
mouse |
| Tuane Bazanella Sampaio, Laíse Figueiredo de Oliveira, Leandra Celso Constantino, Ana Paula Costa, Gabriela Godoy Poluceno, Wagner Carbolin Martins, Tharine Dal-Cim, Karen Andrinéia de Oliveira, Fabiana Kalyne Ludka, Rui Daniel Prediger, Carla Inês Tasca, Frederico C Pereir. Long-Term Neurobehavioral Consequences of a Single Ketamine Neonatal Exposure in Rats: Effects on Cellular Viability and Glutamate Transport in Frontal Cortex and Hippocampus. Neurotoxicity research. vol 34. issue 3. 2018-11-06. PMID:29968149. |
long-term neurobehavioral consequences of a single ketamine neonatal exposure in rats: effects on cellular viability and glutamate transport in frontal cortex and hippocampus. |
2018-11-06 |
2023-08-13 |
rat |
| Tuane Bazanella Sampaio, Laíse Figueiredo de Oliveira, Leandra Celso Constantino, Ana Paula Costa, Gabriela Godoy Poluceno, Wagner Carbolin Martins, Tharine Dal-Cim, Karen Andrinéia de Oliveira, Fabiana Kalyne Ludka, Rui Daniel Prediger, Carla Inês Tasca, Frederico C Pereir. Long-Term Neurobehavioral Consequences of a Single Ketamine Neonatal Exposure in Rats: Effects on Cellular Viability and Glutamate Transport in Frontal Cortex and Hippocampus. Neurotoxicity research. vol 34. issue 3. 2018-11-06. PMID:29968149. |
however, ketamine induced a long-term increase in hippocampal glutamate uptake. |
2018-11-06 |
2023-08-13 |
rat |
| Tuane Bazanella Sampaio, Laíse Figueiredo de Oliveira, Leandra Celso Constantino, Ana Paula Costa, Gabriela Godoy Poluceno, Wagner Carbolin Martins, Tharine Dal-Cim, Karen Andrinéia de Oliveira, Fabiana Kalyne Ludka, Rui Daniel Prediger, Carla Inês Tasca, Frederico C Pereir. Long-Term Neurobehavioral Consequences of a Single Ketamine Neonatal Exposure in Rats: Effects on Cellular Viability and Glutamate Transport in Frontal Cortex and Hippocampus. Neurotoxicity research. vol 34. issue 3. 2018-11-06. PMID:29968149. |
these findings indicate that a single neonatal ketamine exposure induces a short-term reduction in the hippocampal, but not in cortical, cellular viability, and long-term alterations in hippocampal glutamate transport, improvement on motor performance, and short-term recognition memory impairment. |
2018-11-06 |
2023-08-13 |
rat |
| Dariusz Zurawek, Anna Salerno-Kochan, Marta Dziedzicka-Wasylewska, Agnieszka Nikiforuk, Tomasz Kos, Piotr Popi. Changes in the expression of metabotropic glutamate receptor 5 (mGluR5) in a ketamine-based animal model of schizophrenia. Schizophrenia research. vol 192. 2018-11-05. PMID:28433499. |
we postulate that increased expression of mglur5 receptors in the dorsal part of the hippocampus may reflect compensatory changes to imbalanced glutamate neurotransmission associated with the hypoactivation of nmda receptors. |
2018-11-05 |
2023-08-13 |
rat |
| Jiaxian Zhang, Yu Jing, Hu Zhang, David K Bilkey, Ping Li. Effects of maternal immune activation on brain arginine metabolism of postnatal day 2 rat offspring. Schizophrenia research. vol 192. 2018-11-05. PMID:28526281. |
while no effects were evident in the forebrain, mia significantly increased l-arginine, glutamate, putrescine, spermidine and spermine levels and the glutamate/gaba ratio, but decreased the glutamine/glutamate ratio, in the frontal cortex, hippocampus and/or cerebellum with no marked sex differences. |
2018-11-05 |
2023-08-13 |
rat |