| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Martine Hamann, David J Rossi, Hélène Marie, David Attwel. Knocking out the glial glutamate transporter GLT-1 reduces glutamate uptake but does not affect hippocampal glutamate dynamics in early simulated ischaemia. The European journal of neuroscience. vol 15. issue 2. 2002-05-20. PMID:11849297. |
in hippocampal slices from postnatal day 14 mice lacking glt-1, the current response of area ca1 pyramidal cells to superfused ampa and nmda (which are not taken up) was unaffected, whereas the response to 100 microm glutamate was more than doubled relative to that in wild-type littermates, a finding consistent with a decrease in glutamate uptake. |
2002-05-20 |
2023-08-12 |
mouse |
| Ayako M Watabe, Holly J Carlisle, Thomas J O'Del. Postsynaptic induction and presynaptic expression of group 1 mGluR-dependent LTD in the hippocampal CA1 region. Journal of neurophysiology. vol 87. issue 3. 2002-05-20. PMID:11877514. |
activation of metabotropic glutamate receptors (mglurs) with the group i mglur selective agonist (r,s)-3,5-dihydroxyphenylglycine (dhpg) induces a long-term depression (ltd) of excitatory synaptic transmission in the ca1 region of the hippocampus. |
2002-05-20 |
2023-08-12 |
mouse |
| Manickavasagom Alkondon, Edson X Albuquerqu. A non-alpha7 nicotinic acetylcholine receptor modulates excitatory input to hippocampal CA1 interneurons. Journal of neurophysiology. vol 87. issue 3. 2002-05-20. PMID:11877536. |
we conclude that nachr-dependent epsc modulation in the hippocampus is both subtype- and neuron-specific and that a non-alpha7 nachr, presumably alpha3beta4, controls glutamate transmission to ca1 interneurons. |
2002-05-20 |
2023-08-12 |
rat |
| Heyi Li, Linda M Nowak, Kyle R Gee, George P Hes. Mechanism of glutamate receptor-channel function in rat hippocampal neurons investigated using the laser-pulse photolysis (LaPP) technique. Biochemistry. vol 41. issue 15. 2002-05-17. PMID:11939769. |
mechanism of glutamate receptor-channel function in rat hippocampal neurons investigated using the laser-pulse photolysis (lapp) technique. |
2002-05-17 |
2023-08-12 |
rat |
| Heyi Li, Linda M Nowak, Kyle R Gee, George P Hes. Mechanism of glutamate receptor-channel function in rat hippocampal neurons investigated using the laser-pulse photolysis (LaPP) technique. Biochemistry. vol 41. issue 15. 2002-05-17. PMID:11939769. |
the channel-opening mechanism of glutamate receptors was investigated in rat hippocampal neurons voltage-clamped to -60 mv at room temperature and ph 7.4. |
2002-05-17 |
2023-08-12 |
rat |
| Heyi Li, Linda M Nowak, Kyle R Gee, George P Hes. Mechanism of glutamate receptor-channel function in rat hippocampal neurons investigated using the laser-pulse photolysis (LaPP) technique. Biochemistry. vol 41. issue 15. 2002-05-17. PMID:11939769. |
the results suggest that there are at least two forms of glutamate receptors in rat hippocampal neurons that desensitize with different rates. |
2002-05-17 |
2023-08-12 |
rat |
| Zhiguo Chen, Hans-Gustaf Ljunggren, Nenad Bogdanovic, Inger Nennesmo, Bengt Winblad, Jie Zh. Excitotoxic neurodegeneration induced by intranasal administration of kainic acid in C57BL/6 mice. Brain research. vol 931. issue 2. 2002-05-14. PMID:11897099. |
in mice, administration of kainic acid, an analogue of the excitotoxin glutamate, results in hippocampal cell death and seizures. |
2002-05-14 |
2023-08-12 |
mouse |
| M F Yu, T Y Lin, W H Ho, H S Yi. Amphetamine induces differential changes in the gene expression of metabotropic glutamate receptor 5 in cultured cortical and hippocampal neurons. Journal of molecular neuroscience : MN. vol 17. issue 1. 2002-05-10. PMID:11665859. |
amphetamine induces differential changes in the gene expression of metabotropic glutamate receptor 5 in cultured cortical and hippocampal neurons. |
2002-05-10 |
2023-08-12 |
rat |
| C Culmsee, J Monnig, B E Kemp, M P Mattso. AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation. Journal of molecular neuroscience : MN. vol 17. issue 1. 2002-05-10. PMID:11665862. |
the ampk-activating agent aicar protected hippocampal neurons against death induced by glucose deprivation, chemical hypoxia, and exposure to glutamate and amyloid beta-peptide. |
2002-05-10 |
2023-08-12 |
rat |
| T Gos, R Hauser, M Krzyzanowsk. Regional distribution of glutamate in the central nervous system of rat terminated by carbon dioxide euthanasia. Laboratory animals. vol 36. issue 2. 2002-05-09. PMID:11943076. |
two rates of co2 flow were applied, and the higher one significantly augmented the glutamate level in the hippocampus and cerebellum. |
2002-05-09 |
2023-08-12 |
rat |
| A Mazarati, U Langel, T Bartfa. Galanin: an endogenous anticonvulsant? The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 7. issue 6. 2002-05-08. PMID:11765128. |
possible mechanisms of the anticonvulsant action of galanin include its effects on synaptic potentiation in hippocampal circuits and inhibition of the release of the excitatory neurotransmitter glutamate from principal hippocampal neurons. |
2002-05-08 |
2023-08-12 |
mouse |
| I Smolders, C Gousseau, S Marchand, W Couet, G Ebinger, Y Michott. Convulsant and subconvulsant doses of norfloxacin in the presence and absence of biphenylacetic acid alter extracellular hippocampal glutamate but not gamma-aminobutyric acid levels in conscious rats. Antimicrobial agents and chemotherapy. vol 46. issue 2. 2002-05-08. PMID:11796360. |
convulsant and subconvulsant doses of norfloxacin in the presence and absence of biphenylacetic acid alter extracellular hippocampal glutamate but not gamma-aminobutyric acid levels in conscious rats. |
2002-05-08 |
2023-08-12 |
rat |
| I Smolders, C Gousseau, S Marchand, W Couet, G Ebinger, Y Michott. Convulsant and subconvulsant doses of norfloxacin in the presence and absence of biphenylacetic acid alter extracellular hippocampal glutamate but not gamma-aminobutyric acid levels in conscious rats. Antimicrobial agents and chemotherapy. vol 46. issue 2. 2002-05-08. PMID:11796360. |
the present study was undertaken to investigate the possible effects of norfloxacin, both in the absence and in the presence of bpaa, on the extracellular hippocampal levels of gaba and glutamate, the main central inhibitory and excitatory amino acid neurotransmitters, respectively. |
2002-05-08 |
2023-08-12 |
rat |
| I Smolders, C Gousseau, S Marchand, W Couet, G Ebinger, Y Michott. Convulsant and subconvulsant doses of norfloxacin in the presence and absence of biphenylacetic acid alter extracellular hippocampal glutamate but not gamma-aminobutyric acid levels in conscious rats. Antimicrobial agents and chemotherapy. vol 46. issue 2. 2002-05-08. PMID:11796360. |
these norfloxacin-induced convulsions did not affect extracellular hippocampal gaba levels but were accompanied by enhanced glutamate concentrations. |
2002-05-08 |
2023-08-12 |
rat |
| I Smolders, C Gousseau, S Marchand, W Couet, G Ebinger, Y Michott. Convulsant and subconvulsant doses of norfloxacin in the presence and absence of biphenylacetic acid alter extracellular hippocampal glutamate but not gamma-aminobutyric acid levels in conscious rats. Antimicrobial agents and chemotherapy. vol 46. issue 2. 2002-05-08. PMID:11796360. |
in the latter subgroup, again no significant alterations in extracellular gaba levels were observed, but glutamate overflow remained significantly elevated for at least 3 h. in conclusion, norfloxacin exerts convulsant activity in rats, accompanied by elevations of extracellular hippocampal glutamate levels but not gaba levels, even in the presence of bpaa. |
2002-05-08 |
2023-08-12 |
rat |
| F M Benes, M S Todtenkopf, P Kostoulako. GluR5,6,7 subunit immunoreactivity on apical pyramidal cell dendrites in hippocampus of schizophrenics and manic depressives. Hippocampus. vol 11. issue 5. 2002-05-07. PMID:11732702. |
recent postmortem studies have suggested that changes in the regulation of kainate-sensitive glutamate receptors (kainate receptors) in the hippocampus may play a role in schizophrenia. |
2002-05-07 |
2023-08-12 |
Not clear |
| Tomoko Takigawa, Christian Alzheime. Phasic and tonic attenuation of EPSPs by inward rectifier K+ channels in rat hippocampal pyramidal cells. The Journal of physiology. vol 539. issue Pt 1. 2002-05-06. PMID:11850502. |
we made whole-cell recordings from ca1 pyramidal cells of hippocampal slices in combination with brief dendritic glutamate pulses to study the role of constitutive inwardly rectifying k+ channels (irk, kir2.0) and g-protein-activated inwardly rectifying k+ channels (girk, kir3.0) in the processing of excitatory inputs. |
2002-05-06 |
2023-08-12 |
rat |
| Ryuta Koyama, Maki Kobayashi Yamada, Nobuyoshi Nishiyama, Norio Matsuki, Yuji Ikegay. Group II metabotropic glutamate receptor activation is required for normal hippocampal mossy fibre development in the rat. The Journal of physiology. vol 539. issue Pt 1. 2002-05-06. PMID:11850509. |
group ii metabotropic glutamate receptor activation is required for normal hippocampal mossy fibre development in the rat. |
2002-05-06 |
2023-08-12 |
rat |
| Ryuta Koyama, Maki Kobayashi Yamada, Nobuyoshi Nishiyama, Norio Matsuki, Yuji Ikegay. Group II metabotropic glutamate receptor activation is required for normal hippocampal mossy fibre development in the rat. The Journal of physiology. vol 539. issue Pt 1. 2002-05-06. PMID:11850509. |
glutamate is the main neurotransmitter at hippocampal mossy fibre (mf) terminals. |
2002-05-06 |
2023-08-12 |
rat |
| Ryuta Koyama, Maki Kobayashi Yamada, Nobuyoshi Nishiyama, Norio Matsuki, Yuji Ikegay. Group II metabotropic glutamate receptor activation is required for normal hippocampal mossy fibre development in the rat. The Journal of physiology. vol 539. issue Pt 1. 2002-05-06. PMID:11850509. |
the present study may provide a novel role of glutamate in hippocampal development. |
2002-05-06 |
2023-08-12 |
rat |