Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
T Nishizaki, K Nagai, T Nomura, H Tada, T Kanno, H Tozaki, X X Li, T Kondoh, N Kodama, E Takahashi, N Sakai, K Tanaka, N Sait. A new neuromodulatory pathway with a glial contribution mediated via A(2a) adenosine receptors. Glia. vol 39. issue 2. 2002-09-20. PMID:12112365. |
a low concentration (10 nm) of adenosine potentiated hippocampal neuronal activity via a(2a) adenosine receptors without affecting presynaptic glutamate release or postsynaptic glutamatergic conductance. |
2002-09-20 |
2023-08-12 |
Not clear |
T Nishizaki, K Nagai, T Nomura, H Tada, T Kanno, H Tozaki, X X Li, T Kondoh, N Kodama, E Takahashi, N Sakai, K Tanaka, N Sait. A new neuromodulatory pathway with a glial contribution mediated via A(2a) adenosine receptors. Glia. vol 39. issue 2. 2002-09-20. PMID:12112365. |
those adenosine actions could lead to an increase in synaptic glutamate concentrations responsible for the potentiation of hippocampal neuronal activity. |
2002-09-20 |
2023-08-12 |
Not clear |
Zhen Yan, Ping Chi, James A Bibb, Timothy A Ryan, Paul Greengar. Roscovitine: a novel regulator of P/Q-type calcium channels and transmitter release in central neurons. The Journal of physiology. vol 540. issue Pt 3. 2002-09-16. PMID:11986366. |
roscovitine potentiated glutamate release at presynaptic terminals of cultured hippocampal neurons detected with the vesicle trafficking dye fm1-43, consistent with the positive effect of roscovitine on the p/q-type calcium channel, the major mediator of action potential-evoked transmitter release in the mammalian cns. |
2002-09-16 |
2023-08-12 |
mouse |
Christina Spilker, Thomas Dresbach, Karl-Heinz Braunewel. Reversible translocation and activity-dependent localization of the calcium-myristoyl switch protein VILIP-1 to different membrane compartments in living hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 17. 2002-09-13. PMID:12196554. |
interestingly, a fast and reversible translocation of vilip-1-gfp and translocation of endogenous vilip-1 to specialized membrane structures was also observed after a depolarizing stimulus or activation of glutamate receptors in hippocampal neurons. |
2002-09-13 |
2023-08-12 |
Not clear |
Ruifa Mi, Xiaopei Tang, Ralph Sutter, Desheng Xu, Paul Worley, Richard J O'Brie. Differing mechanisms for glutamate receptor aggregation on dendritic spines and shafts in cultured hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 17. 2002-09-13. PMID:12196584. |
differing mechanisms for glutamate receptor aggregation on dendritic spines and shafts in cultured hippocampal neurons. |
2002-09-13 |
2023-08-12 |
Not clear |
Ruifa Mi, Xiaopei Tang, Ralph Sutter, Desheng Xu, Paul Worley, Richard J O'Brie. Differing mechanisms for glutamate receptor aggregation on dendritic spines and shafts in cultured hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 17. 2002-09-13. PMID:12196584. |
we have explored the ability of axons from spinal and hippocampal neurons to aggregate nmda- and ampa-type glutamate receptors on each other as a way of exploring the molecular differences between their presynaptic elements. |
2002-09-13 |
2023-08-12 |
Not clear |
Ruifa Mi, Xiaopei Tang, Ralph Sutter, Desheng Xu, Paul Worley, Richard J O'Brie. Differing mechanisms for glutamate receptor aggregation on dendritic spines and shafts in cultured hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 17. 2002-09-13. PMID:12196584. |
spinal axons, which normally cluster only ampa-type glutamate receptors on other spinal neurons, cluster both ampa- and nmda-type glutamate receptors on the dendritic shafts of hippocampal interneurons but are ineffective at clustering either subtype of glutamate receptor on the dendritic spines of hippocampal pyramidal neurons. |
2002-09-13 |
2023-08-12 |
Not clear |
Ruifa Mi, Xiaopei Tang, Ralph Sutter, Desheng Xu, Paul Worley, Richard J O'Brie. Differing mechanisms for glutamate receptor aggregation on dendritic spines and shafts in cultured hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 17. 2002-09-13. PMID:12196584. |
conversely, hippocampal axons appear to be multipotent, capable of clustering both ampa- and nmda-type glutamate receptors on hippocampal interneurons and pyramidal cells. |
2002-09-13 |
2023-08-12 |
Not clear |
Ruifa Mi, Xiaopei Tang, Ralph Sutter, Desheng Xu, Paul Worley, Richard J O'Brie. Differing mechanisms for glutamate receptor aggregation on dendritic spines and shafts in cultured hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 17. 2002-09-13. PMID:12196584. |
exogenous application of narp to cultured hippocampal neurons results in clusters of both nmda- and ampa-type glutamate receptors on hippocampal interneurons but not hippocampal pyramidal neurons. |
2002-09-13 |
2023-08-12 |
Not clear |
John E Morley, Susan A Farr, James F Floo. Antibody to amyloid beta protein alleviates impaired acquisition, retention, and memory processing in SAMP8 mice. Neurobiology of learning and memory. vol 78. issue 1. 2002-09-10. PMID:12071671. |
arecoline and glutamate were injected directly into the hippocampus, and ketanserin, methiothepen, bicuculline, and oh-saclofen were injected into the septum. |
2002-09-10 |
2023-08-12 |
mouse |
Douglas A Meyer, Mario Carta, L Donald Partridge, Douglas F Covey, C Fernando Valenzuel. Neurosteroids enhance spontaneous glutamate release in hippocampal neurons. Possible role of metabotropic sigma1-like receptors. The Journal of biological chemistry. vol 277. issue 32. 2002-09-09. PMID:12042305. |
neurosteroids enhance spontaneous glutamate release in hippocampal neurons. |
2002-09-09 |
2023-08-12 |
Not clear |
S Attucci, G V Clodfelter, O Thibault, J Staton, F Moroni, P W Landfield, N M Porte. Group I metabotropic glutamate receptor inhibition selectively blocks a prolonged Ca(2+) elevation associated with age-dependent excitotoxicity. Neuroscience. vol 112. issue 1. 2002-09-06. PMID:12044483. |
rat hippocampal cultures of two ages (8-9 and 21-28 days in vitro) were exposed to a 5-min glutamate insult (400 microm in younger and 10 microm in older cultures) sufficient to kill >50% of the neurons, and were treated with vehicle or the specific group i metabotropic glutamate receptor antagonist 1-aminoindan-1,5-dicarboxylic acid (aida; 1 mm), throughout and following the insult. |
2002-09-06 |
2023-08-12 |
rat |
Paul A Rutecki, Umit Sayin, Yili Yang, Eldad Hada. Determinants of ictal epileptiform patterns in the hippocampal slice. Epilepsia. vol 43 Suppl 5. 2002-09-06. PMID:12121317. |
both the muscarinic agonist pilocarpine and the selective group i metabotropic glutamate receptor (mglur) agonist (rs)-3,5-dihydroxyphenylglycine (dhpg) produce prolonged synchronous activity in the hippocampal slice that resembles ictal discharges. |
2002-09-06 |
2023-08-12 |
Not clear |
Guido C Faas, Hita Adwanikar, Robert W Gereau, Peter Sagga. Modulation of presynaptic calcium transients by metabotropic glutamate receptor activation: a differential role in acute depression of synaptic transmission and long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 16. 2002-09-04. PMID:12177186. |
activation of group i metabotropic glutamate receptors (mglurs) can induce acute depression of excitatory synaptic transmission and long-term depression (ltd) in area ca1 of the rat hippocampus. |
2002-09-04 |
2023-08-12 |
rat |
Z L Pontes, L S Oliveira, R Franzon, M Wajner, C M Wannmacher, A T Wys. Inhibition of Na+,K+-ATPase activity from rat hippocampus by proline. Neurochemical research. vol 26. issue 12. 2002-09-03. PMID:11885784. |
in another set of experiments, synaptic plasma membranes were prepared from hippocampus and incubated with proline or glutamate at final concentrations ranging from 0.2 to 2.0 mm. |
2002-09-03 |
2023-08-12 |
rat |
Jehuda P Sepkuty, Akiva S Cohen, Christine Eccles, Azhar Rafiq, Kevin Behar, Raquelli Ganel, Douglas A Coulter, Jeffrey D Rothstei. A neuronal glutamate transporter contributes to neurotransmitter GABA synthesis and epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 15. 2002-09-03. PMID:12151515. |
there was a 50% loss of hippocampal gaba levels associated with knockdown of eaac1, and newly synthesized gaba from extracellular glutamate was significantly impaired by reduction of eaac1 expression. |
2002-09-03 |
2023-08-12 |
rat |
Akiyoshi Uezu, Kohji Fukunaga, Jiro Kasahara, Eishichi Miyamot. Activation of Ca2+/calmodulin-dependent protein kinase I in cultured rat hippocampal neurons. Journal of neurochemistry. vol 82. issue 3. 2002-08-30. PMID:12153482. |
increased activation of cam kinase i occurred by stimulation with glutamate and depolarization in cultured rat hippocampal neurons. |
2002-08-30 |
2023-08-12 |
rat |
L V Lopes, R A Cunha, B Kull, B B Fredholm, J A Ribeir. Adenosine A(2A) receptor facilitation of hippocampal synaptic transmission is dependent on tonic A(1) receptor inhibition. Neuroscience. vol 112. issue 2. 2002-08-29. PMID:12044450. |
cgs 21680 (10 nm) only facilitated (by 17%) the k(+)-evoked release of glutamate from superfused hippocampal synaptosomes in the presence of 100 nm cpa. |
2002-08-29 |
2023-08-12 |
rat |
P Dutar, C Vaillend, C Viollet, J-M Billard, B Potier, A-S Carlo, A Ungerer, J Epelbau. Spatial learning and synaptic hippocampal plasticity in type 2 somatostatin receptor knock-out mice. Neuroscience. vol 112. issue 2. 2002-08-29. PMID:12044463. |
taken together, these data demonstrate that somatostatin, acting via sst2 hippocampal receptors, may contribute to a global decrease in glutamate efficiency and consequently alter glutamate-dependent plasticity and spatial learning. |
2002-08-29 |
2023-08-12 |
mouse |
Kohei Ohta, Tamotsu Nomura, Takeshi Kanno, Kaoru Nagai, Satoshi Yamamoto, Yukio Yajima, Takeshi Kondoh, Eiji Kohmura, Naoaki Saito, Tomoyuki Nishizak. L-trans-PDC enhances hippocampal neuronal activity by stimulating glial glutamate release independently of blocking transporters. Biochemical and biophysical research communications. vol 295. issue 2. 2002-08-29. PMID:12150959. |
l-trans-pdc enhances hippocampal neuronal activity by stimulating glial glutamate release independently of blocking transporters. |
2002-08-29 |
2023-08-12 |
mouse |