| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carlos Beas-Zárate, María Pérez-Vega, Ignacio González-Burgo. Neonatal exposure to monosodium L-glutamate induces loss of neurons and cytoarchitectural alterations in hippocampal CA1 pyramidal neurons of adult rats. Brain research. vol 952. issue 2. 2003-01-07. PMID:12376189. |
these could lead to functional alterations in the hippocampal integrative activity, due to an early cytoexcitotoxic effect of monosodium glutamate. |
2003-01-07 |
2023-08-12 |
rat |
| B Valastro, J Cossette, N Lavoie, S Gagnon, F Trudeau, G Massicott. Up-regulation of glutamate receptors is associated with LTP defects in the early stages of diabetes mellitus. Diabetologia. vol 45. issue 5. 2003-01-03. PMID:12107744. |
recent studies involving electrophysiology and immunolabelling indicate that short-term insulin treatment of hippocampal neurons in culture induces changes in glutamate receptor function, suggesting that this receptor system can be altered on a relatively rapid time scale during diabetic conditions. |
2003-01-03 |
2023-08-12 |
mouse |
| Kaoru Sato, Norio Matsuki, Yasuo Ohno, Ken Nakazaw. Effects of 17beta-estradiol and xenoestrogens on the neuronal survival in an organotypic hippocampal culture. Neuroendocrinology. vol 76. issue 4. 2003-01-03. PMID:12411739. |
when the cultured hippocampal slices were exposed to glutamate (1 mm, 15 min), the ca1-selective neuronal damage was induced. |
2003-01-03 |
2023-08-12 |
Not clear |
| R F Halliwell, Jiping Su, A Demuro, A Martinez-Torres, R Miled. Characterization of the interaction between a novel convulsant agent, norbiphen, and GABA(A) and other ligand-gated ion channels. Neuropharmacology. vol 43. issue 4. 2002-12-24. PMID:12367622. |
sub-maximal gaba-evoked currents recorded from rodent hippocampal neurons were reversibly inhibited by norbiphen (1 microm) to 5+/-2% of control whereas glutamate, nmda and glycine activated responses were little or unaffected. |
2002-12-24 |
2023-08-12 |
human |
| Tetsuro Mohr. [Studies on the cytological function of the biomembrane and the neurons]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 122. issue 10. 2002-12-24. PMID:12400154. |
d-aspartate uptake as a model of glutamate transport was characterized in rat hippocampal slices and found to consist of na(+)-dependent (higher-affinity) and -independent (lower-affinity) components. |
2002-12-24 |
2023-08-12 |
human |
| Sarah Howard, Clement Bottino, Sheila Brooke, Elise Cheng, Rona G Giffard, Robert Sapolsk. Neuroprotective effects of bcl-2 overexpression in hippocampal cultures: interactions with pathways of oxidative damage. Journal of neurochemistry. vol 83. issue 4. 2002-12-24. PMID:12421364. |
we have examined these issues in neuron-enriched primary hippocampal cultures, with overexpression of bcl-2 driven by a herpes simplex virus amplicon: (i) bcl-2 protected strongly against glutamate, whose toxicity is at least partially ros-dependent. |
2002-12-24 |
2023-08-12 |
Not clear |
| Vitaliy S Palamarchouk, Artur H Swiergiel, Adrian J Dun. Hippocampal noradrenergic responses to CRF injected into the locus coeruleus of unanesthetized rats. Brain research. vol 950. issue 1-2. 2002-12-23. PMID:12231226. |
in a recent study using in vivo chronoamperometry in anesthetized rats, crf injected into the lc increased apparent ne release in the hippocampus, but did so after a significant delay, much longer than observed following infusion of glutamate into the same site. |
2002-12-23 |
2023-08-12 |
rat |
| b' M Le\\xc5\\x9bkiewicz, B Budziszewska, L Jaworska-Feil, W Laso\\xc5\\x8. Effect of allopregnanolone on d-[3H]-aspartate release and [3H]-glutamate uptake in the hippocampus of kainate-treated mice. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 53. issue 2. 2002-12-20. PMID:12120899.' |
in order to determine whether the status epilepticus leads to alterations in the neurosteroid effect on excitatory amino acid transmission, we studied the influence of allopregnanolone on aspartate release and glutamate uptake in mouse hippocampus at various times after kainate administration. |
2002-12-20 |
2023-08-12 |
mouse |
| A Takeda, N Sotogaku, N Ok. Manganese influences the levels of neurotransmitters in synapses in rat brain. Neuroscience. vol 114. issue 3. 2002-12-20. PMID:12220568. |
the level of (54)mn in the extracellular space in the hippocampus was increased with that of glutamate, but not with those of gaba and glycine, during stimulation with 100 mm kcl in the presence of 30 microm kainate. |
2002-12-20 |
2023-08-12 |
rat |
| A Takeda, N Sotogaku, N Ok. Manganese influences the levels of neurotransmitters in synapses in rat brain. Neuroscience. vol 114. issue 3. 2002-12-20. PMID:12220568. |
when the rat hippocampus was perfused with artificial cerebrospinal fluid containing 20 or 200 nm mncl(2), the levels of glutamate, aspartate and gaba in the perfusate were dose-dependently decreased during perfusion with manganese. |
2002-12-20 |
2023-08-12 |
rat |
| C H Turner, A G Robling, R L Duncan, D B Bur. Do bone cells behave like a neuronal network? Calcified tissue international. vol 70. issue 6. 2002-12-12. PMID:12149636. |
glutamate is a key neurotransmitter involved in learning and memory in reflex loops and the hippocampus. |
2002-12-12 |
2023-08-12 |
Not clear |
| Y Dong, T S Tang, C L Lu, C He, J B Dong, X Y Huang, F Z Sun, X Ba. [Pituitary adenylate cyclase activating polypeptide ameliorates the damage and inhibits the increase of intracellular calcium concentration in cultured hippocampal neurons induced by glutamate]. Sheng li xue bao : [Acta physiologica Sinica]. vol 52. issue 5. 2002-12-10. PMID:11941395. |
[pituitary adenylate cyclase activating polypeptide ameliorates the damage and inhibits the increase of intracellular calcium concentration in cultured hippocampal neurons induced by glutamate]. |
2002-12-10 |
2023-08-12 |
Not clear |
| Y Dong, T S Tang, C L Lu, C He, J B Dong, X Y Huang, F Z Sun, X Ba. [Pituitary adenylate cyclase activating polypeptide ameliorates the damage and inhibits the increase of intracellular calcium concentration in cultured hippocampal neurons induced by glutamate]. Sheng li xue bao : [Acta physiologica Sinica]. vol 52. issue 5. 2002-12-10. PMID:11941395. |
hippocampal neurons cultured from 7 to 9 d in vitro were used to observe the effect of glutamate. |
2002-12-10 |
2023-08-12 |
Not clear |
| Y Dong, T S Tang, C L Lu, C He, J B Dong, X Y Huang, F Z Sun, X Ba. [Pituitary adenylate cyclase activating polypeptide ameliorates the damage and inhibits the increase of intracellular calcium concentration in cultured hippocampal neurons induced by glutamate]. Sheng li xue bao : [Acta physiologica Sinica]. vol 52. issue 5. 2002-12-10. PMID:11941395. |
treatment of glutamate for 24 h greatly decreased neuronal survival and pretreatment with pituitary adenylate cyclase activating polypeptide (pacap) significantly attenuated hippocampal neuron death induced by glutamate. |
2002-12-10 |
2023-08-12 |
Not clear |
| Y Dong, T S Tang, C L Lu, C He, J B Dong, X Y Huang, F Z Sun, X Ba. [Pituitary adenylate cyclase activating polypeptide ameliorates the damage and inhibits the increase of intracellular calcium concentration in cultured hippocampal neurons induced by glutamate]. Sheng li xue bao : [Acta physiologica Sinica]. vol 52. issue 5. 2002-12-10. PMID:11941395. |
moreover, glutamate dose-dependently increased the intracellular calcium concentration in cultured hippocampal neurons, while pacap inhibited the increase of intracellular calcium concentration induced by glutamate. |
2002-12-10 |
2023-08-12 |
Not clear |
| Y Dong, T S Tang, C L Lu, C He, J B Dong, X Y Huang, F Z Sun, X Ba. [Pituitary adenylate cyclase activating polypeptide ameliorates the damage and inhibits the increase of intracellular calcium concentration in cultured hippocampal neurons induced by glutamate]. Sheng li xue bao : [Acta physiologica Sinica]. vol 52. issue 5. 2002-12-10. PMID:11941395. |
pacap 6-38, a specific pacap type i receptor antagonist, completely inhibited the amelioration of glutamate induced death and the decrease of intracellular calcium concentration induced by pacap in cultured hippocampal neurons. |
2002-12-10 |
2023-08-12 |
Not clear |
| Y Dong, T S Tang, C L Lu, C He, J B Dong, X Y Huang, F Z Sun, X Ba. [Pituitary adenylate cyclase activating polypeptide ameliorates the damage and inhibits the increase of intracellular calcium concentration in cultured hippocampal neurons induced by glutamate]. Sheng li xue bao : [Acta physiologica Sinica]. vol 52. issue 5. 2002-12-10. PMID:11941395. |
the data suggest that pacap has a neuroprotective effect on the hippocampal neuronal damage induced by glutamate, which is related to an inhibition of glutamate-induced increase of intracellular calcium concentration and mediated by pacap type i receptor. |
2002-12-10 |
2023-08-12 |
Not clear |
| Anthony M Rush, John Kilbride, Michael J Rowan, Roger Anwy. Presynaptic group III mGluR modulation of short-term plasticity in the lateral perforant path of the dentate gyrus in vitro. Brain research. vol 952. issue 1. 2002-12-10. PMID:12363402. |
modulation of short-term plasticity by activation of group iii metabotropic glutamate receptors (mglur) was investigated in the lateral perforant path of the dentate gyrus of the rat hippocampus in vitro. |
2002-12-10 |
2023-08-12 |
rat |
| Mako Narisawa-Saito, Yuriko Iwakura, Meiko Kawamura, Kazuaki Araki, Shunji Kozaki, Nobuyuki Takei, Hiroyuki Naw. Brain-derived neurotrophic factor regulates surface expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid receptors by enhancing the N-ethylmaleimide-sensitive factor/GluR2 interaction in developing neocortical neurons. The Journal of biological chemistry. vol 277. issue 43. 2002-12-09. PMID:12130635. |
in hippocampal neurons, the exocytotic process of alpha-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid (ampa)-type glutamate receptors is known to depend on activation of n-methyl-d-aspartate channels and its resultant ca(2+) influx from extracellular spaces. |
2002-12-09 |
2023-08-12 |
human |
| Joachim Behr, Christine Gebhardt, Uwe Heinemann, Istvan Mod. Kindling enhances kainate receptor-mediated depression of GABAergic inhibition in rat granule cells. The European journal of neuroscience. vol 16. issue 5. 2002-12-09. PMID:12372022. |
in kindled preparations, neither glutamate (100 micro m) nor kainate (10 micro m) applied in a concentration known to depolarize hippocampal interneurons led to an increase of the ttx-sensitive spontaneous ipsc frequency nor to changes of the postsynaptic membrane properties. |
2002-12-09 |
2023-08-12 |
rat |