| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Kapur, M Yeckel, D Johnsto. Hippocampal mossy fiber activity evokes Ca2+ release in CA3 pyramidal neurons via a metabotropic glutamate receptor pathway. Neuroscience. vol 107. issue 1. 2002-02-01. PMID:11744247. |
hippocampal mossy fiber activity evokes ca2+ release in ca3 pyramidal neurons via a metabotropic glutamate receptor pathway. |
2002-02-01 |
2023-08-12 |
rat |
| A Kapur, M Yeckel, D Johnsto. Hippocampal mossy fiber activity evokes Ca2+ release in CA3 pyramidal neurons via a metabotropic glutamate receptor pathway. Neuroscience. vol 107. issue 1. 2002-02-01. PMID:11744247. |
using rat hippocampal slices we report here that short trains of mossy fiber stimulation activate group i metabotropic glutamate receptors (mglurs) on ca3 pyramidal neurons and elicit waves of ca2+ release from inositol 1,4,5-trisphosphate (ip3) sensitive internal stores that propagate from stratum lucidum to the soma and in some cases distally out the dendrites. |
2002-02-01 |
2023-08-12 |
rat |
| Ward A Pedersen, Ruiqian Wan, Peisu Zhang, Mark P Mattso. Urocortin, but not urocortin II, protects cultured hippocampal neurons from oxidative and excitotoxic cell death via corticotropin-releasing hormone receptor type I. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 2. 2002-01-30. PMID:11784785. |
here we report that urocortin exerts a potent protective action in cultured rat hippocampal neurons with concentrations in the range of 0.5-5.0 pm, increasing the resistance of the cells to oxidative (amyloid beta-peptide, 4-hydroxynonenal, ferrous sulfate) and excitotoxic (glutamate) insults. |
2002-01-30 |
2023-08-12 |
rat |
| H Yu, R K Iyer, R M Kern, W I Rodriguez, W W Grody, S D Cederbau. Expression of arginase isozymes in mouse brain. Journal of neuroscience research. vol 66. issue 3. 2002-01-25. PMID:11746358. |
glutamic acid decarboxylase 65 and glutamic acid decarboxylase 67, postulated to be related to the risk of glutamate excitotoxic and/or gamma-aminobutyric acid inhibitoxic injury, were similarly ubiquitous in their expression and generally paralleled arginase expression patterns, especially in cerebral cortex, hippocampus, cerebellum, pons, medulla, and spinal cord. |
2002-01-25 |
2023-08-12 |
mouse |
| Y Yang, Q Li, H Miyashita, T Yang, A Shuai. Different dynamic patterns of extracellular glutamate release in rat hippocampus after permanent or 30-min transient cerebral ischemia and histological correlation. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 21. issue 3. 2002-01-24. PMID:11666015. |
different dynamic patterns of extracellular glutamate release in rat hippocampus after permanent or 30-min transient cerebral ischemia and histological correlation. |
2002-01-24 |
2023-08-12 |
rat |
| Y Yang, Q Li, H Miyashita, T Yang, A Shuai. Different dynamic patterns of extracellular glutamate release in rat hippocampus after permanent or 30-min transient cerebral ischemia and histological correlation. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 21. issue 3. 2002-01-24. PMID:11666015. |
to investigate the role of glutamate in cerebral ischemia-reperfusion injury, in vivo microdialysis was performed to examine the dynamic profile of glutamate in the hippocampus in a transient (30 min) or permanent middle cerebral artery occlusion (mcao) in wistar rats. |
2002-01-24 |
2023-08-12 |
rat |
| Y Yang, Q Li, H Miyashita, T Yang, A Shuai. Different dynamic patterns of extracellular glutamate release in rat hippocampus after permanent or 30-min transient cerebral ischemia and histological correlation. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 21. issue 3. 2002-01-24. PMID:11666015. |
the extracellular concentration of glutamate in the cornu ammonis (ca)1 sector of the ipsilateral hippocampus showed a significant but transient elevation of glutamate for both groups immediately following ischemic insult. |
2002-01-24 |
2023-08-12 |
rat |
| T Bruhn, T Christensen, N H Dieme. In vivo cellular uptake of glutamate is impaired in the rat hippocampus during and after transient cerebral ischemia: a microdialysis extraction study. Journal of neuroscience research. vol 66. issue 6. 2002-01-24. PMID:11746444. |
in vivo cellular uptake of glutamate is impaired in the rat hippocampus during and after transient cerebral ischemia: a microdialysis extraction study. |
2002-01-24 |
2023-08-12 |
rat |
| T Bruhn, T Christensen, N H Dieme. In vivo cellular uptake of glutamate is impaired in the rat hippocampus during and after transient cerebral ischemia: a microdialysis extraction study. Journal of neuroscience research. vol 66. issue 6. 2002-01-24. PMID:11746444. |
using microdialysis in ca1 of the rat hippocampus, we studied the effect of transient cerebral ischemia on in vivo uptake and on extracellular levels of glutamate during, and at different time points after ischemia. |
2002-01-24 |
2023-08-12 |
rat |
| N A Datson, J van der Perk, E R de Kloet, E Vreugdenhi. Expression profile of 30,000 genes in rat hippocampus using SAGE. Hippocampus. vol 11. issue 4. 2002-01-23. PMID:11530848. |
comparison of relative expression levels demonstrated that glutamate receptors are the most frequent neurotransmitter receptors expressed in the hippocampus, consistent with the important role of glutamatergic neurotransmission in the hippocampus, while gaba receptors were present at approximately 10-fold lower levels. |
2002-01-23 |
2023-08-12 |
rat |
| N Varma, G C Carlson, C Ledent, B E Alge. Metabotropic glutamate receptors drive the endocannabinoid system in hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 24. 2002-01-23. PMID:11734603. |
metabotropic glutamate receptors drive the endocannabinoid system in hippocampus. |
2002-01-23 |
2023-08-12 |
mouse |
| Jon Nilsen, Roberta Diaz Brinto. Impact of progestins on estrogen-induced neuroprotection: synergy by progesterone and 19-norprogesterone and antagonism by medroxyprogesterone acetate. Endocrinology. vol 143. issue 1. 2002-01-17. PMID:11751611. |
to compare the impact of therapeutically relevant progestins on estrogen-induced neuroprotection, we treated primary hippocampal neuron cultures with 17beta-e2 and progestin, alone and in combination, 48 h before glutamate insult. |
2002-01-17 |
2023-08-12 |
Not clear |
| P Saransaari, S S Oj. Metabotropic glutamate receptors modulate GABA release from mouse hippocampal slices. Neurochemical research. vol 26. issue 2. 2002-01-14. PMID:11478745. |
metabotropic glutamate receptors modulate gaba release from mouse hippocampal slices. |
2002-01-14 |
2023-08-12 |
mouse |
| P Saransaari, S S Oj. Metabotropic glutamate receptors modulate GABA release from mouse hippocampal slices. Neurochemical research. vol 26. issue 2. 2002-01-14. PMID:11478745. |
the effects of metabotropic glutamate receptor agonists on the basal and potassium (50 mm k+)-stimulated release of [3h]gaba from mouse hippocampal slices were investigated using a superfusion system. |
2002-01-14 |
2023-08-12 |
mouse |
| P Saransaari, S S Oj. Metabotropic glutamate receptors modulate GABA release from mouse hippocampal slices. Neurochemical research. vol 26. issue 2. 2002-01-14. PMID:11478745. |
the results show that activation of metabotropic glutamate receptors of group i is able to potentiate the basal release of gaba, whereas activation of groups i and iii receptors reduce k+-stimulated release in mouse hippocampal slices. |
2002-01-14 |
2023-08-12 |
mouse |
| N S Butters, J N Reynolds, J F Brie. In vitro ethanol exposure decreases potassium-stimulated, but not veratridine-stimulated, glutamate release in the guinea pig hippocampus. Alcohol (Fayetteville, N.Y.). vol 25. issue 1. 2002-01-14. PMID:11668017. |
in vitro ethanol exposure decreases potassium-stimulated, but not veratridine-stimulated, glutamate release in the guinea pig hippocampus. |
2002-01-14 |
2023-08-12 |
Not clear |
| N S Butters, J N Reynolds, J F Brie. In vitro ethanol exposure decreases potassium-stimulated, but not veratridine-stimulated, glutamate release in the guinea pig hippocampus. Alcohol (Fayetteville, N.Y.). vol 25. issue 1. 2002-01-14. PMID:11668017. |
in this study we determined the effect of in vitro ethanol exposure on stimulated glutamate release in transverse hippocampal slices (400-microm thickness) of the young postnatal guinea pig (pd 12) by using two chemical stimuli with different mechanisms of action. |
2002-01-14 |
2023-08-12 |
Not clear |
| N S Butters, J N Reynolds, J F Brie. In vitro ethanol exposure decreases potassium-stimulated, but not veratridine-stimulated, glutamate release in the guinea pig hippocampus. Alcohol (Fayetteville, N.Y.). vol 25. issue 1. 2002-01-14. PMID:11668017. |
the study findings demonstrate that in vitro ethanol exposure produces differential inhibition of stimulated glutamate release in the hippocampus, dependent on the stimulating agent. |
2002-01-14 |
2023-08-12 |
Not clear |
| T Mabuchi, K Kitagawa, K Kuwabara, K Takasawa, T Ohtsuki, Z Xia, D Storm, T Yanagihara, M Hori, M Matsumot. Phosphorylation of cAMP response element-binding protein in hippocampal neurons as a protective response after exposure to glutamate in vitro and ischemia in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 23. 2002-01-11. PMID:11717354. |
phosphorylation of camp response element-binding protein in hippocampal neurons as a protective response after exposure to glutamate in vitro and ischemia in vivo. |
2002-01-11 |
2023-08-12 |
mouse |
| T Mabuchi, K Kitagawa, K Kuwabara, K Takasawa, T Ohtsuki, Z Xia, D Storm, T Yanagihara, M Hori, M Matsumot. Phosphorylation of cAMP response element-binding protein in hippocampal neurons as a protective response after exposure to glutamate in vitro and ischemia in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 23. 2002-01-11. PMID:11717354. |
in the present study, we clarified that (1) creb phosphorylation and ischemic tolerance induced after preconditioning ischemia in the hippocampal neurons was abolished by mk801 administration in gerbil global ischemia model, (2) creb phosphorylation induced after exposure to glutamate in cultured neurons was inhibited by removal of extracellular calcium, by mk801 and by an inhibitor of calcium-calmodulin-dependent protein kinase (camk) ii and iv, (3) inhibitor of camk ii-iv or cre-decoy oligonucleotide suppressed upregulation of bcl-2 expression and accelerated neuronal damage after exposure to glutamate, and (4) creb phosphorylation induced in the hippocampal neurons after ischemia and in cultured neurons after exposure to glutamate was followed by cre-mediated gene transcription in transgenic mice with a cre-lacz reporter. |
2002-01-11 |
2023-08-12 |
mouse |