| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Qin, G S Marrs, R McKim, M E Daile. Hippocampal mossy fibers induce assembly and clustering of PSD95-containing postsynaptic densities independent of glutamate receptor activation. The Journal of comparative neurology. vol 440. issue 3. 2002-01-11. PMID:11745624. |
hippocampal mossy fibers induce assembly and clustering of psd95-containing postsynaptic densities independent of glutamate receptor activation. |
2002-01-11 |
2023-08-12 |
rat |
| A Kelly, A Lynch, E Vereker, Y Nolan, P Queenan, E Whittaker, L A O'Neill, M A Lync. The anti-inflammatory cytokine, interleukin (IL)-10, blocks the inhibitory effect of IL-1 beta on long term potentiation. A role for JNK. The Journal of biological chemistry. vol 276. issue 49. 2002-01-10. PMID:11581275. |
among these changes are an il-1 beta-induced inhibition of long term potentiation (ltp) in perforant path-granule cell synapses and an attenuation of glutamate release in synaptosomes prepared from the hippocampus. |
2002-01-10 |
2023-08-12 |
Not clear |
| H Xia, Z D Hornby, R C Malenk. An ER retention signal explains differences in surface expression of NMDA and AMPA receptor subunits. Neuropharmacology. vol 41. issue 6. 2002-01-10. PMID:11640925. |
to determine the role of the intracellular c-terminal tails of glutamate receptor subunits in the synaptic targeting of ampars and nmdars, we fused the tails of the ampar subunits, glur1 and glur2, and the nmdar subunit, nr1, to the human t lymphocyte membrane protein cd8 and expressed these constructs in hek293 cells and cultured hippocampal neurons. |
2002-01-10 |
2023-08-12 |
human |
| S G Brickley, M Farrant, G T Swanson, S G Cull-Cand. CNQX increases GABA-mediated synaptic transmission in the cerebellum by an AMPA/kainate receptor-independent mechanism. Neuropharmacology. vol 41. issue 6. 2002-01-10. PMID:11640927. |
these results demonstrate that the novel excitatory action of cnqx, unrelated to blockade of ionotropic glutamate receptors, is not restricted to the hippocampus and can be observed with structurally related compounds. |
2002-01-10 |
2023-08-12 |
Not clear |
| M Kokaia, K Holmberg, A Nanobashvili, Z Q Xu, Z Kokaia, U Lendahl, S Hilke, E Theodorsson, U Kahl, T Bartfai, O Lindvall, T Hökfel. Suppressed kindling epileptogenesis in mice with ectopic overexpression of galanin. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 24. 2002-01-08. PMID:11698649. |
frequency facilitation of field excitatory postsynaptic potentials, a form of short-term synaptic plasticity assessed in hippocampal slices, was reduced in mossy fiber-ca3 cell synapses of galanin-overexpressing mice, indicating suppressed glutamate release. |
2002-01-08 |
2023-08-12 |
mouse |
| L Massieu, P Del Río, T Montie. Neurotoxicity of glutamate uptake inhibition in vivo: correlation with succinate dehydrogenase activity and prevention by energy substrates. Neuroscience. vol 106. issue 4. 2002-01-04. PMID:11682154. |
in previous studies we have shown that glutamate uptake inhibition by l-trans-pyrrolidine-2,4-dicarboxylate (pdc) in the rat striatum and hippocampus in vivo does not induce neuronal death despite the notable increase in the extracellular levels of glutamate and aspartate. |
2002-01-04 |
2023-08-12 |
rat |
| K Tominaga-Yoshino, T Uetsuki, K Yoshikawa, A Ogur. Neurotoxic and neuroprotective effects of glutamate are enhanced by introduction of amyloid precursor protein cDNA. Brain research. vol 918. issue 1-2. 2002-01-04. PMID:11684050. |
from the enhanced responsiveness to glutamate in cultured hippocampal neurons after the introduction of cdna of app695 (an isoform of app dominant in human brain) using an adenovirus vector, we have recently raised the hypothesis that app modulates neuronal sensitivity to glutamate. |
2002-01-04 |
2023-08-12 |
human |
| K Tominaga-Yoshino, T Uetsuki, K Yoshikawa, A Ogur. Neurotoxic and neuroprotective effects of glutamate are enhanced by introduction of amyloid precursor protein cDNA. Brain research. vol 918. issue 1-2. 2002-01-04. PMID:11684050. |
it is known that hippocampal neurons undergo deterioration in 24 h after application of glutamate in a dose-dependent manner. |
2002-01-04 |
2023-08-12 |
human |
| K Tominaga-Yoshino, T Uetsuki, K Yoshikawa, A Ogur. Neurotoxic and neuroprotective effects of glutamate are enhanced by introduction of amyloid precursor protein cDNA. Brain research. vol 918. issue 1-2. 2002-01-04. PMID:11684050. |
these enhancing effects of app on the glutamate-induced vulnerability in hippocampal neurons and the glutamate (nmda)-dependent survival in cerebellar neurons were blocked by glutamate receptor inhibitors, and were not seen after application of a control adenovirus carrying cdna of beta-galactosidase. |
2002-01-04 |
2023-08-12 |
human |
| D M Barros, T Mello e Souza, T De David, H Choi, A Aguzzoli, C Madche, P Ardenghi, J H Medina, I Izquierd. Simultaneous modulation of retrieval by dopaminergic D(1), beta-noradrenergic, serotonergic-1A and cholinergic muscarinic receptors in cortical structures of the rat. Behavioural brain research. vol 124. issue 1. 2002-01-03. PMID:11423160. |
retrieval of inhibitory avoidance has been recently shown to require intact glutamate receptors, protein kinases a and c and mitogen-activated protein kinase in the ca1 region of the rat hippocampus and in the entorhinal, posterior parietal and anterior cingulate cortex. |
2002-01-03 |
2023-08-12 |
rat |
| S Brecht, M Gelderblom, A Srinivasan, K Mielke, G Dityateva, T Herdege. Caspase-3 activation and DNA fragmentation in primary hippocampal neurons following glutamate excitotoxicity. Brain research. Molecular brain research. vol 94. issue 1-2. 2002-01-03. PMID:11597762. |
caspase-3 activation and dna fragmentation in primary hippocampal neurons following glutamate excitotoxicity. |
2002-01-03 |
2023-08-12 |
mouse |
| M C Lee, S S Ban, Y J Woo, S U Ki. Calcium/calmodulin kinase II activity of hippocampus in kainate-induced epilepsy. Journal of Korean medical science. vol 16. issue 5. 2002-01-03. PMID:11641537. |
the above results indicate that intra-amygdaloid injection of ka produces excitatory signals for ipsilateral ca3 neurons in the hippocampus and that subsequently increased levels of camkii in postsynaptic neurons induce neuronal injury via phosphorylation of n-methyl-d-aspartate type glutamate receptor. |
2002-01-03 |
2023-08-12 |
Not clear |
| L A Dawson, H Q Nguyen, P L. The 5-HT(6) receptor antagonist SB-271046 selectively enhances excitatory neurotransmission in the rat frontal cortex and hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 5. 2002-01-03. PMID:11682249. |
conversely, sb-271046 produced 3- and 2-fold increases in extracellular glutamate levels in both frontal cortex and dorsal hippocampus, respectively. |
2002-01-03 |
2023-08-12 |
rat |
| D M Kullman. Presynaptic kainate receptors in the hippocampus: slowly emerging from obscurity. Neuron. vol 32. issue 4. 2002-01-03. PMID:11719198. |
because synaptically released glutamate mimics many of the actions of exogenous agonists, presynaptic kainate receptors potentially play an extensive role in hippocampal signaling. |
2002-01-03 |
2023-08-12 |
Not clear |
| F R Tang, W L Le. Expression of the group II and III metabotropic glutamate receptors in the hippocampus of patients with mesial temporal lobe epilepsy. Journal of neurocytology. vol 30. issue 2. 2001-12-14. PMID:11577252. |
expression of the group ii and iii metabotropic glutamate receptors in the hippocampus of patients with mesial temporal lobe epilepsy. |
2001-12-14 |
2023-08-12 |
Not clear |
| Y Kitao, K Ozawa, M Miyazaki, M Tamatani, T Kobayashi, H Yanagi, M Okabe, M Ikawa, T Yamashima, D M Stern, O Hori, S Ogaw. Expression of the endoplasmic reticulum molecular chaperone (ORP150) rescues hippocampal neurons from glutamate toxicity. The Journal of clinical investigation. vol 108. issue 10. 2001-12-13. PMID:11714735. |
expression of the endoplasmic reticulum molecular chaperone (orp150) rescues hippocampal neurons from glutamate toxicity. |
2001-12-13 |
2023-08-12 |
mouse |
| M D Glitsch, J J Jac. Evidence that glutamate acting on presynaptic type-II metabotropic glutamate receptors alone does not fully account for the phenomenon of depolarisation-induced suppression of inhibition in cerebellar Purkinje cells. Pflugers Archiv : European journal of physiology. vol 442. issue 3. 2001-12-12. PMID:11484772. |
pharmacological studies have indicated that glutamate might be a retrograde messenger in both cerebellum and hippocampus, where, in the former at least, it seems to activate type-ii metabotropic glutamate receptors (mglurs). |
2001-12-12 |
2023-08-12 |
Not clear |
| R Franco, M E Torres-Márquez, H Pasantes-Morale. Evidence for two mechanisms of amino acid osmolyte release from hippocampal slices. Pflugers Archiv : European journal of physiology. vol 442. issue 5. 2001-12-11. PMID:11512036. |
a 30% decrease in osmolarity stimulated 3h-taurine, 3h-gaba and glutamate (followed as 3h-d-aspartate) efflux from rat hippocampal slices. |
2001-12-11 |
2023-08-12 |
rat |
| R Franco, M E Torres-Márquez, H Pasantes-Morale. Evidence for two mechanisms of amino acid osmolyte release from hippocampal slices. Pflugers Archiv : European journal of physiology. vol 442. issue 5. 2001-12-11. PMID:11512036. |
this novel mechanism of amino acid release may be mediated by ca2+-independent exocytosis and modulated by pkc and actin cytoskeleton disruption, as suggested by its inhibition by chelerythrine and potentiation by 100 nm phorbol-12-myristate-13 acetate (pma) and cytochalasin e. gaba and glutamate osmosensitive efflux may explain the hyposmolarity-elicited increase in amplitude of inhibitory and excitatory postsynaptic potentials in hippocampal slices as well as the hyperexcitability associated with hyponatraemia. |
2001-12-11 |
2023-08-12 |
rat |
| R A Chambers, J H Krystal, D W Sel. A neurobiological basis for substance abuse comorbidity in schizophrenia. Biological psychiatry. vol 50. issue 2. 2001-12-10. PMID:11526998. |
in this model, disturbances in drug reward are mediated, in part, by dysregulated neural integration of dopamine and glutamate signaling in the nucleus accumbens resulting form frontal cortical and hippocampal dysfunction. |
2001-12-10 |
2023-08-12 |
Not clear |