| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Meenakshi Bawari, G Nagesh Bab. Metabolic responses in discrete regions of rat brain following acute administration of glutamate. Neurochemical research. vol 28. issue 9. 2003-09-05. PMID:12938856. |
in the present study, 1 microm of glutamate was stereotactically injected into cerebral cortex, striatum, and hippocampus of adult rat brain, and the activities of key metabolic enzymes, lactate dehydrogenase, glutamate dehydrogenase, aspartate aminotransferase, and alanine aminotransferase were evaluated by postmortem analysis in tissue homogenates. |
2003-09-05 |
2023-08-12 |
rat |
| J S Bonini, L Rodrigues, D S Kerr, L R M Bevilaqua, M Cammarota, I Izquierd. AMPA/kainate and group-I metabotropic receptor antagonists infused into different brain areas impair memory formation of inhibitory avoidance in rats. Behavioural pharmacology. vol 14. issue 2. 2003-09-03. PMID:12658077. |
to examine the role of non-n-methyl-d-aspartate (non-nmda) glutamate receptors on memory consolidation, rats were bilaterally implanted with cannulae aimed at the ca1 region of the dorsal hippocampus (ca1), entorhinal cortex (ento), posterior parietal cortex (ppc) or the basolateral nucleus of the amygdala (bla), and trained in a one-trial step-down inhibitory avoidance task. |
2003-09-03 |
2023-08-12 |
rat |
| Atsushi Takeda, Maki Hirate, Haruna Tamano, Naoto Ok. Zinc movement in the brain under kainate-induced seizures. Epilepsy research. vol 54. issue 2-3. 2003-09-03. PMID:12837563. |
in the hippocampus of rats injected with kainate (10 mg/kg), furthermore, the release of zinc and glutamate into the extracellular fluid was studied using in vivo microdialysis. |
2003-09-03 |
2023-08-12 |
mouse |
| Axel Becker, Brigitte Peters, Helmut Schroeder, Tobias Mann, Gerald Huether, Gisela Grecksc. Ketamine-induced changes in rat behaviour: A possible animal model of schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 27. issue 4. 2003-08-29. PMID:12787858. |
ket treatment leads to an increase in d2 receptor binding in the hippocampus and a decrease in glutamate receptor binding in the frontal cortex. |
2003-08-29 |
2023-08-12 |
rat |
| Tommi Möykkynen, Esa R Korpi, David M Lovinge. Ethanol inhibits alpha-amino-3-hydyroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor function in central nervous system neurons by stabilizing desensitization. The Journal of pharmacology and experimental therapeutics. vol 306. issue 2. 2003-08-28. PMID:12734392. |
ethanol actions on alpha-amino-3-hydyroxy-5-methyl-4-isoxazolepropionic acid (ampa)-type glutamate receptors were studied using voltage-clamp recordings from mouse cortical and hippocampal neurons. |
2003-08-28 |
2023-08-12 |
mouse |
| Suhas A Kotecha, Michael F Jackson, Azza Al-Mahrouki, John C Roder, Beverley A Orser, John F MacDonal. Co-stimulation of mGluR5 and N-methyl-D-aspartate receptors is required for potentiation of excitatory synaptic transmission in hippocampal neurons. The Journal of biological chemistry. vol 278. issue 30. 2003-08-26. PMID:12740378. |
interestingly, stimulation of group i metabotropic glutamate receptors (mglurs) can either enhance or depress synaptic transmission at ca1 hippocampal synapses. |
2003-08-26 |
2023-08-12 |
Not clear |
| Osamu Miyamoto, Kazuyoshi Tamae, Hiroshi Kasai, Haruhisa Hirakawa, Yoshiaki Hayashida, Ryoji Konishi, Toshifumi Itan. Suppression of hyperemia and DNA oxidation by indomethacin in cerebral ischemia. European journal of pharmacology. vol 459. issue 2-3. 2003-08-25. PMID:12524144. |
in addition, indomethacin attenuated the increase in hippocampal blood flow during reperfusion, but not increased extracellular glutamate by ischemia. |
2003-08-25 |
2023-08-12 |
Not clear |
| Maria Passafaro, Terunaga Nakagawa, Carlo Sala, Morgan Shen. Induction of dendritic spines by an extracellular domain of AMPA receptor subunit GluR2. Nature. vol 424. issue 6949. 2003-08-25. PMID:12904794. |
here we show that overexpression of the glutamate receptor 2 (glur2) subunit of ampa receptors increases spine size and density in hippocampal neurons, and more remarkably, induces spine formation in gaba-releasing interneurons that normally lack spines. |
2003-08-25 |
2023-08-12 |
Not clear |
| Norbert Hájos, Tamás F Freun. Distinct cannabinoid sensitive receptors regulate hippocampal excitation and inhibition. Chemistry and physics of lipids. vol 121. issue 1-2. 2003-08-22. PMID:12505692. |
novel, non-cb1 cannabinoid sensitive receptors are present on the hippocampal excitatory axon terminals, which suppress glutamate release. |
2003-08-22 |
2023-08-12 |
Not clear |
| Christine E Gee, Pascal Benquet, Urs Gerbe. Group I metabotropic glutamate receptors activate a calcium-sensitive transient receptor potential-like conductance in rat hippocampus. The Journal of physiology. vol 546. issue Pt 3. 2003-08-20. PMID:12562994. |
group i metabotropic glutamate receptors activate a calcium-sensitive transient receptor potential-like conductance in rat hippocampus. |
2003-08-20 |
2023-08-12 |
rat |
| Sung-Jin An, Tae-Cheon Kang, Seung-Kook Park, In-Koo Hwang, Sa Sun Cho, Myung-Hee Chung, Moo Ho Wo. Oxidative DNA damage and alteration of glutamate transporter expressions in the hippocampal Ca1 area immediately after ischemic insult. Molecules and cells. vol 13. issue 3. 2003-08-19. PMID:12132589. |
therefore, in the present study, using the gerbil global ischemic model we investigated whether oxidative stress could be correlated with the expression of the glutamate transporters in the hippocampus, and whether these events are related and cooperate in the events that link ischemia to neuronal death in vivo. |
2003-08-19 |
2023-08-12 |
Not clear |
| C Bonde, A Sarup, A Schousboe, G Gegelashvili, J Zimmer, J Noraber. Neurotoxic and neuroprotective effects of the glutamate transporter inhibitor DL-threo-beta-benzyloxyaspartate (DL-TBOA) during physiological and ischemia-like conditions. Neurochemistry international. vol 43. issue 4-5. 2003-08-19. PMID:12742081. |
in this study the cellular localisation of the glutamate transporters glast and glt-1 in organotypic hippocampal slice cultures was studied by immunofluorescence confocal microscopy, under normal culture conditions, and after a simulated ischemic insult, achieved by oxygen and glucose deprivation (ogd). |
2003-08-19 |
2023-08-12 |
Not clear |
| C Bonde, A Sarup, A Schousboe, G Gegelashvili, J Zimmer, J Noraber. Neurotoxic and neuroprotective effects of the glutamate transporter inhibitor DL-threo-beta-benzyloxyaspartate (DL-TBOA) during physiological and ischemia-like conditions. Neurochemistry international. vol 43. issue 4-5. 2003-08-19. PMID:12742081. |
it is concluded: (1) that the cellular expression of the glutamate transporters glast and glt-1 in hippocampal slice cultures in general corresponds to the expression in vivo, (2) that inhibition of the glutamate transporters induces cell death in the slice cultures, and (3) that partial inhibition during simulation of ischemia by ogd protects against the induced pi uptake, most likely by blocking the reverse operating transporters otherwise triggered by the energy failure. |
2003-08-19 |
2023-08-12 |
Not clear |
| C Bonde, A Sarup, A Schousboe, G Gegelashvili, J Noraberg, J Zimme. GDNF pre-treatment aggravates neuronal cell loss in oxygen-glucose deprived hippocampal slice cultures: a possible effect of glutamate transporter up-regulation. Neurochemistry international. vol 43. issue 4-5. 2003-08-19. PMID:12742082. |
gdnf pre-treatment aggravates neuronal cell loss in oxygen-glucose deprived hippocampal slice cultures: a possible effect of glutamate transporter up-regulation. |
2003-08-19 |
2023-08-12 |
rat |
| C Bonde, A Sarup, A Schousboe, G Gegelashvili, J Noraberg, J Zimme. GDNF pre-treatment aggravates neuronal cell loss in oxygen-glucose deprived hippocampal slice cultures: a possible effect of glutamate transporter up-regulation. Neurochemistry international. vol 43. issue 4-5. 2003-08-19. PMID:12742082. |
organotypic hippocampal slice cultures, derived from 1-week-old rats, were treated with 100 ng/ml gdnf for either 2 or 5 days, followed by western blot analysis of nmdar subunit 1 (nr1) and two glutamate transporter subtypes, glast and glt-1. |
2003-08-19 |
2023-08-12 |
rat |
| Sirpa Rainesalo, Tapani Keränen, Jukka Peltola, Pirjo Saransaar. Glutamate uptake in blood platelets from epileptic patients. Neurochemistry international. vol 43. issue 4-5. 2003-08-19. PMID:12742083. |
we studied glutamate uptake into blood platelets from patients with distinct epileptic syndromes: included were 20 patients with temporal lobe epilepsy and hippocampal sclerosis (tle+hs), 20 with juvenile myoclonus epilepsy (jme) and 20 healthy volunteers matched for age and sex. |
2003-08-19 |
2023-08-12 |
human |
| Pirjo Saransaari, Simo S Oj. Characteristics of GABA release modified by glutamate receptors in mouse hippocampal slices. Neurochemistry international. vol 43. issue 4-5. 2003-08-19. PMID:12742091. |
characteristics of gaba release modified by glutamate receptors in mouse hippocampal slices. |
2003-08-19 |
2023-08-12 |
mouse |
| Pirjo Saransaari, Simo S Oj. Characteristics of GABA release modified by glutamate receptors in mouse hippocampal slices. Neurochemistry international. vol 43. issue 4-5. 2003-08-19. PMID:12742091. |
the modulation of [(3)h]gaba release by ionotropic and metabotropic glutamate receptors and by nitric oxide was here characterized in superfused mouse hippocampal slices. |
2003-08-19 |
2023-08-12 |
mouse |
| Pirjo Saransaari, Simo S Oj. Characteristics of GABA release modified by glutamate receptors in mouse hippocampal slices. Neurochemistry international. vol 43. issue 4-5. 2003-08-19. PMID:12742091. |
the k(+)-stimulated hippocampal gaba release was reduced by the groups i and iii agonists of metabotropic glutamate receptors (+/-)-1-aminocyclopentane-trans-1,3-dicarboxylate (t-acpd) and l-(+)-2-amino-4-phosphonobutyrate (l-ap4), which effects were abolished by their respective antagonists (rs)-1-aminoindan-1,5-dicarboxylate (aida) and (rs)-2-cyclopropyl-4-phosphonophenylglycine (cppg), again indicating modification by receptor-mediated mechanisms. |
2003-08-19 |
2023-08-12 |
mouse |
| Michelle L Byrnes, James N Reynolds, James F Brie. Brain growth spurt-prenatal ethanol exposure and the guinea pig hippocampal glutamate signaling system. Neurotoxicology and teratology. vol 25. issue 3. 2003-08-19. PMID:12757827. |
brain growth spurt-prenatal ethanol exposure and the guinea pig hippocampal glutamate signaling system. |
2003-08-19 |
2023-08-12 |
Not clear |