| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pari Malherbe, James N C Kew, J Grayson Richards, Frédéric Knoflach, Claudia Kratzeisen, Marie-Thérèse Zenner, Richard L M Faull, John A Kemp, Vincent Mute. Identification and characterization of a novel splice variant of the metabotropic glutamate receptor 5 gene in human hippocampus and cerebellum. Brain research. Molecular brain research. vol 109. issue 1-2. 2003-07-01. PMID:12531526. |
identification and characterization of a novel splice variant of the metabotropic glutamate receptor 5 gene in human hippocampus and cerebellum. |
2003-07-01 |
2023-08-12 |
human |
| Michael Spedding, Isabelle Neau, Laszlo Harsin. Brain plasticity and pathology in psychiatric disease: sites of action for potential therapy. Current opinion in pharmacology. vol 3. issue 1. 2003-07-01. PMID:12550739. |
recent advances have been made in understanding the changes in neuronal plasticity in psychiatric disease at the molecular level (changes in neurotransmission, long-term potentiation, long-term depression, glutamate receptors, synaptic strength and neurotrophic support) and the systems level (changes in hippocampal, frontal and amygdala function in health and disease and the impact of stress on the hippocampal/frontal axis), as well as in the impact of drugs and sites of action for therapeutic intervention. |
2003-07-01 |
2023-08-12 |
Not clear |
| Nan-Jie Xu, Lan Bao, Hua-Ping Fan, Guo-Bin Bao, Lu Pu, Ying-Jin Lu, Chun-Fu Wu, Xu Zhang, Gang Pe. Morphine withdrawal increases glutamate uptake and surface expression of glutamate transporter GLT1 at hippocampal synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 11. 2003-07-01. PMID:12805317. |
morphine withdrawal increases glutamate uptake and surface expression of glutamate transporter glt1 at hippocampal synapses. |
2003-07-01 |
2023-08-12 |
rat |
| Nan-Jie Xu, Lan Bao, Hua-Ping Fan, Guo-Bin Bao, Lu Pu, Ying-Jin Lu, Chun-Fu Wu, Xu Zhang, Gang Pe. Morphine withdrawal increases glutamate uptake and surface expression of glutamate transporter GLT1 at hippocampal synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 11. 2003-07-01. PMID:12805317. |
in the present study, we found that glutamate uptake in hippocampal synaptosomes was significantly increased (by 70% in chronic morphine-treated rats) during the morphine withdrawal period, likely attributable to an increase in the number of functional glutamate transporters. |
2003-07-01 |
2023-08-12 |
rat |
| Ana P Silva, Paulo S Pinheiro, Arsélio P Carvalho, Caetana M Carvalho, Birthe Jakobsen, Jens Zimmer, João O Malv. Activation of neuropeptide Y receptors is neuroprotective against excitotoxicity in organotypic hippocampal slice cultures. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 17. issue 9. 2003-06-25. PMID:12692082. |
glutamate and npy have been implicated in hippocampal neuropathology in temporal lobe epilepsy. |
2003-06-25 |
2023-08-12 |
rat |
| Ana P Silva, Paulo S Pinheiro, Arsélio P Carvalho, Caetana M Carvalho, Birthe Jakobsen, Jens Zimmer, João O Malv. Activation of neuropeptide Y receptors is neuroprotective against excitotoxicity in organotypic hippocampal slice cultures. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 17. issue 9. 2003-06-25. PMID:12692082. |
based on the present findings, it was concluded that y1, y2, and y5 receptors effectively can modify glutamate receptor-mediated neurodegeneration in the hippocampus. |
2003-06-25 |
2023-08-12 |
rat |
| J Wu, R Xia, N Shi, Y Li. [Effects of pyrethroids on the glutamate uptake system in synaptic vesicle of rats]. Wei sheng yan jiu = Journal of hygiene research. vol 28. issue 5. 2003-06-23. PMID:12712690. |
the results showed that cypermethrin and permethrin in the concentration of 10(-9)-10(-4) mol/l could inhibit the high affinity uptake of glutamate in the synaptosomes of cerebral cortex, hippocampus and striatum in a dose-response manner. |
2003-06-23 |
2023-08-12 |
rat |
| Zuner A Bortolotto, Sari Lauri, John T R Isaac, Graham L Collingridg. Kainate receptors and the induction of mossy fibre long-term potentiation. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 358. issue 1432. 2003-06-20. PMID:12740111. |
this article summarizes the evidence that the kainate subtype of glutamate receptor is an important trigger for the induction of ltp at mossy fibre synapses in the ca3 region of the hippocampus. |
2003-06-20 |
2023-08-12 |
mouse |
| M L Errington, P T Galley, T V P Blis. Long-term potentiation in the dentate gyrus of the anaesthetized rat is accompanied by an increase in extracellular glutamate: real-time measurements using a novel dialysis electrode. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 358. issue 1432. 2003-06-20. PMID:12740113. |
we have used a glutamate-specific dialysis electrode to obtain real-time measurements of changes in the concentration of glutamate in the extracellular space of the hippocampus during low-frequency stimulation and following the induction of long-term potentiation (ltp). |
2003-06-20 |
2023-08-12 |
rat |
| Ana Leonor A Nencioni, Ivo Lebrun, Valquiria A C Dorc. A microdialysis study of glutamate concentration in the hippocampus of rats after TsTX toxin injection and blockade of toxin effects by glutamate receptor antagonists. Pharmacology, biochemistry, and behavior. vol 74. issue 2. 2003-06-18. PMID:12479967. |
a microdialysis study of glutamate concentration in the hippocampus of rats after tstx toxin injection and blockade of toxin effects by glutamate receptor antagonists. |
2003-06-18 |
2023-08-12 |
rat |
| Ana Leonor A Nencioni, Ivo Lebrun, Valquiria A C Dorc. A microdialysis study of glutamate concentration in the hippocampus of rats after TsTX toxin injection and blockade of toxin effects by glutamate receptor antagonists. Pharmacology, biochemistry, and behavior. vol 74. issue 2. 2003-06-18. PMID:12479967. |
the microdialysis method revealed enhanced levels of extracellular glutamate in the hippocampal area. |
2003-06-18 |
2023-08-12 |
rat |
| L Bianchi, C Ballini, M A Colivicchi, L Della Corte, M G Giovannini, G Pepe. Investigation on acetylcholine, aspartate, glutamate and GABA extracellular levels from ventral hippocampus during repeated exploratory activity in the rat. Neurochemical research. vol 28. issue 3-4. 2003-06-18. PMID:12675146. |
investigation on acetylcholine, aspartate, glutamate and gaba extracellular levels from ventral hippocampus during repeated exploratory activity in the rat. |
2003-06-18 |
2023-08-12 |
rat |
| L Bianchi, C Ballini, M A Colivicchi, L Della Corte, M G Giovannini, G Pepe. Investigation on acetylcholine, aspartate, glutamate and GABA extracellular levels from ventral hippocampus during repeated exploratory activity in the rat. Neurochemical research. vol 28. issue 3-4. 2003-06-18. PMID:12675146. |
the extracellular levels of aspartate, glutamate, gamma-aminobutyric acid (gaba), and acetylcholine (ach) were investigated by microdialysis, coupled with hplc, in the ventral hippocampus of rats during two 30-min exploration periods. |
2003-06-18 |
2023-08-12 |
rat |
| L Bianchi, C Ballini, M A Colivicchi, L Della Corte, M G Giovannini, G Pepe. Investigation on acetylcholine, aspartate, glutamate and GABA extracellular levels from ventral hippocampus during repeated exploratory activity in the rat. Neurochemical research. vol 28. issue 3-4. 2003-06-18. PMID:12675146. |
in conclusion, exploratory activity is associated with or depends on the activation of neuronal systems in the ventral hippocampus releasing aspartate, glutamate, gaba, and ach. |
2003-06-18 |
2023-08-12 |
rat |
| Giampaolo Mereu, Mauro Fà, Luca Ferraro, Raffaele Cagiano, Tiziana Antonelli, Maria Tattoli, Veronica Ghiglieri, Sergio Tanganelli, Gian Luigi Gessa, Vincenzo Cuom. Prenatal exposure to a cannabinoid agonist produces memory deficits linked to dysfunction in hippocampal long-term potentiation and glutamate release. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 8. 2003-06-17. PMID:12679519. |
prenatal exposure to a cannabinoid agonist produces memory deficits linked to dysfunction in hippocampal long-term potentiation and glutamate release. |
2003-06-17 |
2023-08-12 |
rat |
| Giampaolo Mereu, Mauro Fà, Luca Ferraro, Raffaele Cagiano, Tiziana Antonelli, Maria Tattoli, Veronica Ghiglieri, Sergio Tanganelli, Gian Luigi Gessa, Vincenzo Cuom. Prenatal exposure to a cannabinoid agonist produces memory deficits linked to dysfunction in hippocampal long-term potentiation and glutamate release. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 8. 2003-06-17. PMID:12679519. |
the memory impairment caused by the gestational exposure to win was correlated with alterations of hippocampal long-term potentiation (ltp) and glutamate release. |
2003-06-17 |
2023-08-12 |
rat |
| Giampaolo Mereu, Mauro Fà, Luca Ferraro, Raffaele Cagiano, Tiziana Antonelli, Maria Tattoli, Veronica Ghiglieri, Sergio Tanganelli, Gian Luigi Gessa, Vincenzo Cuom. Prenatal exposure to a cannabinoid agonist produces memory deficits linked to dysfunction in hippocampal long-term potentiation and glutamate release. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 8. 2003-06-17. PMID:12679519. |
in line with ltp shortening, in vivo microdialysis showed a significant decrease in basal and k(+)-evoked extracellular glutamate levels in the hippocampus of juvenile and adult rats born from win-treated dams. |
2003-06-17 |
2023-08-12 |
rat |
| Giampaolo Mereu, Mauro Fà, Luca Ferraro, Raffaele Cagiano, Tiziana Antonelli, Maria Tattoli, Veronica Ghiglieri, Sergio Tanganelli, Gian Luigi Gessa, Vincenzo Cuom. Prenatal exposure to a cannabinoid agonist produces memory deficits linked to dysfunction in hippocampal long-term potentiation and glutamate release. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 8. 2003-06-17. PMID:12679519. |
a similar reduction in glutamate outflow was also observed in primary cell cultures of hippocampus obtained from pups born from mothers exposed to win. |
2003-06-17 |
2023-08-12 |
rat |
| Giampaolo Mereu, Mauro Fà, Luca Ferraro, Raffaele Cagiano, Tiziana Antonelli, Maria Tattoli, Veronica Ghiglieri, Sergio Tanganelli, Gian Luigi Gessa, Vincenzo Cuom. Prenatal exposure to a cannabinoid agonist produces memory deficits linked to dysfunction in hippocampal long-term potentiation and glutamate release. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 8. 2003-06-17. PMID:12679519. |
the decrease in hippocampal glutamate outflow appears to be the cause of ltp disruption, which in turn might underlie, at least in part, the long-lasting impairment of cognitive functions caused by the gestational exposure to this cannabinoid agonist. |
2003-06-17 |
2023-08-12 |
rat |
| Daniela M Barros, Luciana A Izquierdo, Jorge H Medina, Ivan Izquierd. Pharmacological findings contribute to the understanding of the main physiological mechanisms of memory retrieval. Current drug targets. CNS and neurological disorders. vol 2. issue 2. 2003-06-17. PMID:12769801. |
recent pharmacological findings have shown that retrieval of one-trial avoidance learning requires glutamate receptors, camp-dependent protein kinase and mitogen-activated protein kinases in the hippocampus, entorhinal, posterior parietal and anterior cingulate cortex. |
2003-06-17 |
2023-08-12 |
Not clear |