| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sachiko Tanaka, Akihiro Tsuchida, Yuji Kiuchi, Katsuji Oguchi, Satoshi Numazawa, Takemi Yoshid. GABAergic modulation of hippocampal glutamatergic neurons: an in vivo microdialysis study. European journal of pharmacology. vol 465. issue 1-2. 2003-07-21. PMID:12650834. |
these results suggest that gaba modulates depolarization-evoked glutamate release in the hippocampus by inhibiting ca(2+) entry into neurons, an effect mediated by presynaptic gaba(b) receptors. |
2003-07-21 |
2023-08-12 |
rat |
| P M Thomas, J P Phillips, N Delanty, W T O'Conno. Elevated extracellular levels of glutamate, aspartate and gamma-aminobutyric acid within the intraoperative, spontaneously epileptiform human hippocampus. Epilepsy research. vol 54. issue 1. 2003-07-21. PMID:12742599. |
elevated extracellular levels of glutamate, aspartate and gamma-aminobutyric acid within the intraoperative, spontaneously epileptiform human hippocampus. |
2003-07-21 |
2023-08-12 |
human |
| P M Thomas, J P Phillips, N Delanty, W T O'Conno. Elevated extracellular levels of glutamate, aspartate and gamma-aminobutyric acid within the intraoperative, spontaneously epileptiform human hippocampus. Epilepsy research. vol 54. issue 1. 2003-07-21. PMID:12742599. |
in two cases, spontaneously vigorous hippocampal epileptiform activity (ea) was identified; basal dialysate levels for hippocampal glutamate, aspartate, and gamma-aminobutyric acid ranged from approximately 23- to 84-fold, 19- to 33-fold and 10- to 34-fold higher, respectively, compared to the two cases of minimal hippocampal ea. |
2003-07-21 |
2023-08-12 |
human |
| Elisa Roncati Zanier, Stefan M Lee, Paul M Vespa, Christopher C Giza, David A Hovd. Increased hippocampal CA3 vulnerability to low-level kainic acid following lateral fluid percussion injury. Journal of neurotrauma. vol 20. issue 5. 2003-07-17. PMID:12803974. |
this study was designed to determine whether a secondary increase in neuronal activity induced by a low dose of kainic acid (ka), a glutamate analogue, exacerbates the anatomical damage in hippocampal regions following a mild lateral fluid percussion (lfp) brain injury. |
2003-07-17 |
2023-08-12 |
rat |
| Gail K Seabold, Alain Burette, Indra A Lim, Richard J Weinberg, Johannes W Hel. Interaction of the tyrosine kinase Pyk2 with the N-methyl-D-aspartate receptor complex via the Src homology 3 domains of PSD-95 and SAP102. The Journal of biological chemistry. vol 278. issue 17. 2003-07-16. PMID:12576483. |
at hippocampal synapses, induction of long term potentiation requires the pyk2/src signaling pathway, which up-regulates the activity of n-methyl-d-aspartate-type glutamate receptors. |
2003-07-16 |
2023-08-12 |
Not clear |
| Yun-Chia Chou, Shin-Bey Lin, Lien Hsin Tsai, Hung-I Tsai, Chiao Mei Li. Cholesterol deficiency increases the vulnerability of hippocampal glia in primary culture to glutamate-induced excitotoxicity. Neurochemistry international. vol 43. issue 3. 2003-07-16. PMID:12689600. |
this study was undertaken to investigate the mechanism by which cholesterol shortage modulates glutamate (glu)-induced excitotoxicity in hippocampal cell cultures. |
2003-07-16 |
2023-08-12 |
Not clear |
| Wen-Biao Ga. Glutamate-dependent stabilization of presynaptic terminals. Neuron. vol 38. issue 5. 2003-07-16. PMID:12797951. |
and by hashimoto and kano in this issue of neuron provide new insights into the roles of neurotransmitter glutamate release in regulating the motility of hippocampal mossy fiber filopodia and synaptic competition among climbing fibers. |
2003-07-16 |
2023-08-12 |
Not clear |
| Guido Mannaioni, Raffaella Carpenedo, Flavio Moron. 5-hydroxyindole causes convulsions and increases transmitter release in the CA1 region of the rat hippocampus. British journal of pharmacology. vol 138. issue 1. 2003-07-15. PMID:12522096. |
2 local administration of 5-ohi into the ca1 region of the rat hippocampus, via a microdialysis probe, significantly increased glutamate concentrations in the dialysates. |
2003-07-15 |
2023-08-12 |
rat |
| Yueh-Ting Chou, Shiau-Ting Lai, Chin-Cheng Lee, Mao-Tsun Li. Hypothermia attenuates circulatory shock and cerebral ischemia in experimental heatstroke. Shock (Augusta, Ga.). vol 19. issue 4. 2003-07-14. PMID:12688553. |
control rats were exposed to 26 degrees c. extracellular concentrations of glutamate, glycerol, lactate, and lactate/pyruvate in the hippocampus were assessed by microdialysis methods. |
2003-07-14 |
2023-08-12 |
rat |
| Sheila M Brooke, Robert M Sapolsk. Effects of glucocorticoids in the gp120-induced inhibition of glutamate uptake in hippocampal cultures. Brain research. vol 972. issue 1-2. 2003-07-11. PMID:12711086. |
effects of glucocorticoids in the gp120-induced inhibition of glutamate uptake in hippocampal cultures. |
2003-07-11 |
2023-08-12 |
Not clear |
| Jennifer Bendiske, Ben A Bah. Lysosomal activation is a compensatory response against protein accumulation and associated synaptopathogenesis--an approach for slowing Alzheimer disease? Journal of neuropathology and experimental neurology. vol 62. issue 5. 2003-07-09. PMID:12769185. |
in the hippocampal slice model, tau deposits and amyloidogenic fragments induced by the lysosomal inhibitor chloroquine were accompanied by disrupted microtubule integrity and by corresponding declines in postsynaptic glutamate receptors and the presynaptic marker synaptophysin. |
2003-07-09 |
2023-08-12 |
Not clear |
| Nektaria Ioannou, Charis Liapi, Constantine E Sekeris, George Palaiologo. Effects of dexamethasone on K(+)-evoked glutamate release from rat hippocampal slices. Neurochemical research. vol 28. issue 6. 2003-07-08. PMID:12718441. |
effects of dexamethasone on k(+)-evoked glutamate release from rat hippocampal slices. |
2003-07-08 |
2023-08-12 |
rat |
| Nektaria Ioannou, Charis Liapi, Constantine E Sekeris, George Palaiologo. Effects of dexamethasone on K(+)-evoked glutamate release from rat hippocampal slices. Neurochemical research. vol 28. issue 6. 2003-07-08. PMID:12718441. |
dexamethasone (dex) at physiologically elevated (stress) concentration (1 microm) decreased k(+)-evoked glutamate release from rat hippocampal slices under superfusion in the presence of ca2+. |
2003-07-08 |
2023-08-12 |
rat |
| Umit Sayin, Paul A Ruteck. Group I metabotropic glutamate receptor activation produces prolonged epileptiform neuronal synchronization and alters evoked population responses in the hippocampus. Epilepsy research. vol 53. issue 3. 2003-07-07. PMID:12694926. |
group i metabotropic glutamate receptor activation produces prolonged epileptiform neuronal synchronization and alters evoked population responses in the hippocampus. |
2003-07-07 |
2023-08-12 |
rat |
| Umit Sayin, Paul A Ruteck. Group I metabotropic glutamate receptor activation produces prolonged epileptiform neuronal synchronization and alters evoked population responses in the hippocampus. Epilepsy research. vol 53. issue 3. 2003-07-07. PMID:12694926. |
we used the ca3 region of the adult rat hippocampal slice to evaluate group i metabotropic glutamate receptor (mglur) activation on epileptiform activity and the population response recorded extracellularly evoked by stratum radiatum stimulation. |
2003-07-07 |
2023-08-12 |
rat |
| Bin Lin, Amy C Arai, Gary Lynch, Christine M Gal. Integrins regulate NMDA receptor-mediated synaptic currents. Journal of neurophysiology. vol 89. issue 5. 2003-07-02. PMID:12740418. |
excitatory postsynaptic currents (epscs) were recorded with whole cell clamp from hippocampal slices in which ampa-type glutamate receptors and gaba(a) receptors were pharmacologically blocked. |
2003-07-02 |
2023-08-12 |
Not clear |
| Hitoshi Tada, Motoi Uchino, Kaoru Nagai, Tamotsu Nomura, Takeshi Kondoh, Naoaki Saito, Takehira Yamamura, Yukio Yajima, Tomoyuki Nishizak. The anti-dementia drug FK960 stimulates glial glutamate release via a PKA pathway. Brain research. Molecular brain research. vol 109. issue 1-2. 2003-07-01. PMID:12531516. |
fk960 facilitated hippocampal neurotransmission in normal mice, and also in mice lacking the glial glutamate transporter, glt-1 (glut-1(-/-)), but to a lesser extent. |
2003-07-01 |
2023-08-12 |
mouse |
| Hitoshi Tada, Motoi Uchino, Kaoru Nagai, Tamotsu Nomura, Takeshi Kondoh, Naoaki Saito, Takehira Yamamura, Yukio Yajima, Tomoyuki Nishizak. The anti-dementia drug FK960 stimulates glial glutamate release via a PKA pathway. Brain research. Molecular brain research. vol 109. issue 1-2. 2003-07-01. PMID:12531516. |
fk960 enhanced glutamate release from cultured hippocampal astrocytes from normal rats and mice, while the drug had no effect on the release from cultured rat hippocampal neurons. |
2003-07-01 |
2023-08-12 |
mouse |
| Hitoshi Tada, Motoi Uchino, Kaoru Nagai, Tamotsu Nomura, Takeshi Kondoh, Naoaki Saito, Takehira Yamamura, Yukio Yajima, Tomoyuki Nishizak. The anti-dementia drug FK960 stimulates glial glutamate release via a PKA pathway. Brain research. Molecular brain research. vol 109. issue 1-2. 2003-07-01. PMID:12531516. |
the glutamate release was still obtained with cultured hippocampal astrocytes from glut-1(-/-) mice, suggesting that the release is not due to glt-1-mediated counter transport of glutamate. |
2003-07-01 |
2023-08-12 |
mouse |
| Hitoshi Tada, Motoi Uchino, Kaoru Nagai, Tamotsu Nomura, Takeshi Kondoh, Naoaki Saito, Takehira Yamamura, Yukio Yajima, Tomoyuki Nishizak. The anti-dementia drug FK960 stimulates glial glutamate release via a PKA pathway. Brain research. Molecular brain research. vol 109. issue 1-2. 2003-07-01. PMID:12531516. |
the fk960 action would increase synaptic glutamate concentrations, in part responsible for the facilitation of hippocampal neurotransmission. |
2003-07-01 |
2023-08-12 |
mouse |