| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Steven J Feinmark, Roxana Begum, Evgeny Tsvetkov, Ivan Goussakov, Colin D Funk, Steven A Siegelbaum, Vadim Y Bolshako. 12-lipoxygenase metabolites of arachidonic acid mediate metabotropic glutamate receptor-dependent long-term depression at hippocampal CA3-CA1 synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 36. 2004-01-16. PMID:14673007. |
we found that the 12-lipoxygenase pathway is required for the induction of metabotropic glutamate receptor-dependent ltd (mglur-ltd), but is not required for ltp: (1) hippocampal homogenates were capable of synthesizing the 12-lipoxygenase metabolite of arachidonic acid, 12(s)-hydroxyeicosa-5z,8z,10e,14z-tetraenoic acid (hete). |
2004-01-16 |
2023-08-12 |
mouse |
| James O'Donnell, Jeanne Stemmelin, Atsumi Nitta, Jonathan Brouillette, Rémi Quirio. Gene expression profiling following chronic NMDA receptor blockade-induced learning deficits in rats. Synapse (New York, N.Y.). vol 50. issue 3. 2004-01-06. PMID:14515334. |
among other genes found to be most changed in the hippocampus were protein kinase c beta i and ii, protein tyrosine phosphatase 1beta, neuropilin i and ii, adenosine receptor a1, and metabotropic glutamate receptor 2/3. |
2004-01-06 |
2023-08-12 |
rat |
| James O'Donnell, Jeanne Stemmelin, Atsumi Nitta, Jonathan Brouillette, Rémi Quirio. Gene expression profiling following chronic NMDA receptor blockade-induced learning deficits in rats. Synapse (New York, N.Y.). vol 50. issue 3. 2004-01-06. PMID:14515334. |
in the hippocampus, protein kinase c beta i and ii, protein tyrosine phosphatase, neuropilin i and ii, adenosine receptor a, metabotropic glutamate receptor 2/3, and in the striatum phosphatidyl inositol 4 kinase, mitogen-activated protein kinase 1, adenylyl cyclase ii, dopamine receptors 1a and 2, and cytochrome c oxidase subunit va gene and protein expression levels were found to be highly correlated. |
2004-01-06 |
2023-08-12 |
rat |
| Michael Wong, Kevin C Ess, Erik J Uhlmann, Laura A Jansen, Wen Li, Peter B Crino, Steven Mennerick, Kelvin A Yamada, David H Gutman. Impaired glial glutamate transport in a mouse tuberous sclerosis epilepsy model. Annals of neurology. vol 54. issue 2. 2004-01-05. PMID:12891680. |
electrophysiological assays demonstrate a functional decrease in glutamate transport currents of tsc1 cko astrocytes in hippocampal slices and astrocyte cultures. |
2004-01-05 |
2023-08-12 |
mouse |
| Osamu Miyamoto, Jinming Pang, Kazunori Sumitani, Tetsuro Negi, Yoshiaki Hayashida, Toshifumi Itan. Mechanisms of the anti-ischemic effect of vagus nerve stimulation in the gerbil hippocampus. Neuroreport. vol 14. issue 15. 2004-01-05. PMID:14561931. |
vns significantly attenuated both ischemia-induced glutamate release and transient increase of hippocampal blood flow during reperfusion. |
2004-01-05 |
2023-08-12 |
Not clear |
| Karen L Gilliams-Francis, Aurora A Quaye, Janice R Naegel. PARP cleavage, DNA fragmentation, and pyknosis during excitotoxin-induced neuronal death. Experimental neurology. vol 184. issue 1. 2004-01-05. PMID:14637106. |
parp-1 is activated by dna damage in neurons of the hippocampus and cerebral cortex following excessive exposure to glutamate receptor agonists such as nmda or kainic acid. |
2004-01-05 |
2023-08-12 |
Not clear |
| J V Selkirk, G S Naeve, A C Foste. Blockade of excitatory amino acid transporters in the rat hippocampus results in enhanced activation of group I and group III metabotropic glutamate receptors. Neuropharmacology. vol 45. issue 7. 2003-12-29. PMID:14573381. |
blockade of excitatory amino acid transporters in the rat hippocampus results in enhanced activation of group i and group iii metabotropic glutamate receptors. |
2003-12-29 |
2023-08-12 |
rat |
| J V Selkirk, G S Naeve, A C Foste. Blockade of excitatory amino acid transporters in the rat hippocampus results in enhanced activation of group I and group III metabotropic glutamate receptors. Neuropharmacology. vol 45. issue 7. 2003-12-29. PMID:14573381. |
the idea that excitatory amino acid transporters (eaats) can control the activation of specific metabotropic glutamate receptors (mglurs) was investigated in rat hippocampal slices. |
2003-12-29 |
2023-08-12 |
rat |
| Gabriela X Ayala, Ricardo Tapi. Expression of heat shock protein 70 induced by 4-aminopyridine through glutamate-mediated excitotoxic stress in rat hippocampus in vivo. Neuropharmacology. vol 45. issue 5. 2003-12-19. PMID:12941378. |
these data demonstrate that the 4-ap-induced release of endogenous glutamate overactivates nmda receptors in the perfused hippocampus and that the resulting neuronal hyperexcitability propagates to the contralateral hippocampus, generating a glutamate-mediated neuronal stress sufficient to induce the expression of hsp70 but not to produce neurodegeneration. |
2003-12-19 |
2023-08-12 |
rat |
| Attila Köfalvi, E Sylvester Vizi, Catherine Ledent, Beáta Sperlág. Cannabinoids inhibit the release of [3H]glutamate from rodent hippocampal synaptosomes via a novel CB1 receptor-independent action. The European journal of neuroscience. vol 18. issue 7. 2003-12-19. PMID:14622229. |
cannabinoids inhibit the release of [3h]glutamate from rodent hippocampal synaptosomes via a novel cb1 receptor-independent action. |
2003-12-19 |
2023-08-12 |
mouse |
| Attila Köfalvi, E Sylvester Vizi, Catherine Ledent, Beáta Sperlág. Cannabinoids inhibit the release of [3H]glutamate from rodent hippocampal synaptosomes via a novel CB1 receptor-independent action. The European journal of neuroscience. vol 18. issue 7. 2003-12-19. PMID:14622229. |
in this study we investigated the effect of cannabinoids on [3h]glutamate release from hippocampal synaptosomes of rat and cb1-null mutant mouse. |
2003-12-19 |
2023-08-12 |
mouse |
| Attila Köfalvi, E Sylvester Vizi, Catherine Ledent, Beáta Sperlág. Cannabinoids inhibit the release of [3H]glutamate from rodent hippocampal synaptosomes via a novel CB1 receptor-independent action. The European journal of neuroscience. vol 18. issue 7. 2003-12-19. PMID:14622229. |
these data demonstrate that the action of cannabinoids on glutamate release in the hippocampus is pharmacologically distinct and independent from the cloned cb1 receptor. |
2003-12-19 |
2023-08-12 |
mouse |
| Charles P Gilman, TracyAnn Perry, Katsotoshi Furukawa, Nigel H Grieg, Josephine M Egan, Mark P Mattso. Glucagon-like peptide 1 modulates calcium responses to glutamate and membrane depolarization in hippocampal neurons. Journal of neurochemistry. vol 87. issue 5. 2003-12-18. PMID:14622093. |
glucagon-like peptide 1 modulates calcium responses to glutamate and membrane depolarization in hippocampal neurons. |
2003-12-18 |
2023-08-12 |
rat |
| I Ferrer, B Pui. GluR2/3, NMDAepsilon1 and GABAA receptors in Creutzfeldt-Jakob disease. Acta neuropathologica. vol 106. issue 4. 2003-12-17. PMID:12835949. |
glutamate receptors ampa glur2/3 and nmda r2a: nr2a (nmdaepsilon1), and gaba(a) (gaba(a) ralpha1) receptors were examined by immunohistochemistry in the cerebral cortex (frontal cortex) entorhinal cortex, hippocampus and cerebellar cortex in nine patients with sporadic creutzfeldt-jakob disease (cjd) and eight age-matched controls obtained 3-8 h after death. |
2003-12-17 |
2023-08-12 |
Not clear |
| Tobias Bast, Wei-Ning Zhang, Joram Feldo. Dorsal hippocampus and classical fear conditioning to tone and context in rats: effects of local NMDA-receptor blockade and stimulation. Hippocampus. vol 13. issue 6. 2003-12-12. PMID:12962312. |
in particular, a specific and central role in contextual fear conditioning has been attributed to mechanisms mediated by dorsal hippocampal n-methyl-d-aspartate (nmda)-type glutamate receptors. |
2003-12-12 |
2023-08-12 |
rat |
| Serap Sirvanci, Charles K Meshul, Filiz Onat, Tangul Sa. Immunocytochemical analysis of glutamate and GABA in hippocampus of genetic absence epilepsy rats (GAERS). Brain research. vol 988. issue 1-2. 2003-12-10. PMID:14519540. |
immunocytochemical analysis of glutamate and gaba in hippocampus of genetic absence epilepsy rats (gaers). |
2003-12-10 |
2023-08-12 |
rat |
| Serap Sirvanci, Charles K Meshul, Filiz Onat, Tangul Sa. Immunocytochemical analysis of glutamate and GABA in hippocampus of genetic absence epilepsy rats (GAERS). Brain research. vol 988. issue 1-2. 2003-12-10. PMID:14519540. |
in the present study, we used an immunocytochemical technique at the electron microscopic level to determine if there are changes in the glutamate and gaba neurotransmitter content of the hippocampus of genetic absence epilepsy rats from strasbourg (gaers). |
2003-12-10 |
2023-08-12 |
rat |
| Serap Sirvanci, Charles K Meshul, Filiz Onat, Tangul Sa. Immunocytochemical analysis of glutamate and GABA in hippocampus of genetic absence epilepsy rats (GAERS). Brain research. vol 988. issue 1-2. 2003-12-10. PMID:14519540. |
glutamate density in the ca3 region of gaers hippocampus was found to be significantly increased compared to the control group. |
2003-12-10 |
2023-08-12 |
rat |
| J Lu, D Goula, N Sousa, O F X Almeid. Ionotropic and metabotropic glutamate receptor mediation of glucocorticoid-induced apoptosis in hippocampal cells and the neuroprotective role of synaptic N-methyl-D-aspartate receptors. Neuroscience. vol 121. issue 1. 2003-12-05. PMID:12946705. |
ionotropic and metabotropic glutamate receptor mediation of glucocorticoid-induced apoptosis in hippocampal cells and the neuroprotective role of synaptic n-methyl-d-aspartate receptors. |
2003-12-05 |
2023-08-12 |
rat |
| J Lu, D Goula, N Sousa, O F X Almeid. Ionotropic and metabotropic glutamate receptor mediation of glucocorticoid-induced apoptosis in hippocampal cells and the neuroprotective role of synaptic N-methyl-D-aspartate receptors. Neuroscience. vol 121. issue 1. 2003-12-05. PMID:12946705. |
glutamate receptors have been proposed to mediate the apoptotic actions of glucocorticoids in hippocampal cells. |
2003-12-05 |
2023-08-12 |
rat |