| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chiung-Chun Huang, Cheng-Che Lee, Kuei-Sen Hs. An investigation into signal transduction mechanisms involved in insulin-induced long-term depression in the CA1 region of the hippocampus. Journal of neurochemistry. vol 89. issue 1. 2004-04-26. PMID:15030406. |
using electrophysiological and biochemical approaches in the hippocampal slices, we show here that insulin-ltd (i) is specific to 3-hydroxy-5-methylisoxazole-4-propionic acid (ampa) receptor- but not nmda receptor-mediated synaptic transmission; (ii) is induced and expressed postsynaptically but does not require the activation of ionotropic and metabotropic glutamate receptors; (iii) requires a concomitant ca(2+) influx through l-type voltage-activated ca(2+) channels (vaccs) and the release of ca(2+) from intracellular stores; (iv) requires the series of protein kinases, including protein tyrosine kinase (ptk), phosphatidylinositol 3-kinase (pi3k), and protein kinase c (pkc); (v) is mechanistically distinct from low-frequency stimulation-induced ltd (lfs-ltd) and independent on protein phosphatase 1/2 a (pp1/2 a) and pp2b activation; (vi) is dependent on a rapamycin-sensitive local translation of dendritic mrna, and (vii) is associated with a persistent decrease in the surface expression of glur2 subunit. |
2004-04-26 |
2023-08-12 |
Not clear |
| Gwendolyn E Wood, L Trevor Young, Lawrence P Reagan, Biao Chen, Bruce S McEwe. Stress-induced structural remodeling in hippocampus: prevention by lithium treatment. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 11. 2004-04-23. PMID:15001711. |
chronic lithium treatment prevented the stress-induced decrease in dendritic length, as well as the stress-induced increase in glial glutamate transporter 1 (glt-1) mrna expression and the phosphorylation of camp-response element binding in the hippocampus. |
2004-04-23 |
2023-08-12 |
rat |
| Isabel J Hildebrandt, Jennifer L Termeer, Delilah Toledo, Randy W Cohe. Characterization of chronic nicotine exposure on the survival of the spastic Han-Wistar rat. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 5. issue 6. 2004-04-22. PMID:14668067. |
we investigated the possible neuroprotective effects of nicotine in the spastic han-wistar rat, which suffers from glutamate excitotoxicity affecting two central nervous system regions: the hippocampus and the cerebellum. |
2004-04-22 |
2023-08-12 |
rat |
| Christopher P Bailey, Jesus A Trejos, Francis A X Schanne, Patric K Stanto. Pairing elevation of [cyclic GMP] with inhibition of PKA produces long-term depression of glutamate release from isolated rat hippocampal presynaptic terminals. The European journal of neuroscience. vol 17. issue 4. 2004-04-21. PMID:12603282. |
pairing elevation of [cyclic gmp] with inhibition of pka produces long-term depression of glutamate release from isolated rat hippocampal presynaptic terminals. |
2004-04-21 |
2023-08-12 |
rat |
| Christopher P Bailey, Jesus A Trejos, Francis A X Schanne, Patric K Stanto. Pairing elevation of [cyclic GMP] with inhibition of PKA produces long-term depression of glutamate release from isolated rat hippocampal presynaptic terminals. The European journal of neuroscience. vol 17. issue 4. 2004-04-21. PMID:12603282. |
these data demonstrate the existence of a presynaptic, cyclic gmp-pkg dependent cascade capable of expressing ltd of glutamate release from isolated hippocampal nerve terminals. |
2004-04-21 |
2023-08-12 |
rat |
| Takao Yoshimizu, Shigeyuki Chak. Increased cell proliferation in the adult mouse hippocampus following chronic administration of group II metabotropic glutamate receptor antagonist, MGS0039. Biochemical and biophysical research communications. vol 315. issue 2. 2004-04-20. PMID:14766235. |
increased cell proliferation in the adult mouse hippocampus following chronic administration of group ii metabotropic glutamate receptor antagonist, mgs0039. |
2004-04-20 |
2023-08-12 |
mouse |
| Trevor J Bushell, Gilles Sansig, Valerie J Collett, Herman van der Putten, Graham L Collingridg. Altered short-term synaptic plasticity in mice lacking the metabotropic glutamate receptor mGlu7. TheScientificWorldJournal. vol 2. 2004-04-19. PMID:12805997. |
eight subtypes of metabotropic glutamate (mglu) receptors have been identified of which two, mglu5 and mglu7, are highly expressed at synapses made between ca3 and ca1 pyramidal neurons in the hippocampus. |
2004-04-19 |
2023-08-12 |
mouse |
| Weizhi Chen, Veeravan Mahadomrongkul, Urs V Berger, Merav Bassan, Tara DeSilva, Kohichi Tanaka, Nina Irwin, Chiye Aoki, Paul A Rosenber. The glutamate transporter GLT1a is expressed in excitatory axon terminals of mature hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 5. 2004-04-15. PMID:14762132. |
the glutamate transporter glt1a is expressed in excitatory axon terminals of mature hippocampal neurons. |
2004-04-15 |
2023-08-12 |
mouse |
| Weizhi Chen, Veeravan Mahadomrongkul, Urs V Berger, Merav Bassan, Tara DeSilva, Kohichi Tanaka, Nina Irwin, Chiye Aoki, Paul A Rosenber. The glutamate transporter GLT1a is expressed in excitatory axon terminals of mature hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 5. 2004-04-15. PMID:14762132. |
thus, the originally cloned form of glt1, glt1a, is expressed as protein in neurons in the mature hippocampus and may contribute significantly to glutamate uptake into excitatory terminals. |
2004-04-15 |
2023-08-12 |
mouse |
| Ingrid Ehrlich, Roberto Malino. Postsynaptic density 95 controls AMPA receptor incorporation during long-term potentiation and experience-driven synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 4. 2004-04-12. PMID:14749436. |
in hippocampal slice cultures, the expression of psd-95-green fluorescent protein (psd-95-gfp) increases ampar currents by selectively delivering glutamate receptor 1 (glur1)-containing receptors to synapses, thus mimicking long-term potentiation (ltp). |
2004-04-12 |
2023-08-12 |
Not clear |
| Iman H Brivanlou, Jami L M Dantzker, Charles F Stevens, Edward M Callawa. Topographic specificity of functional connections from hippocampal CA3 to CA1. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 8. 2004-04-09. PMID:14983048. |
here, we used a physiological method (photostimulation with caged glutamate) to probe the fine pattern of functional connectivity between the ca3 and ca1 subfields in the mouse hippocampal slice preparation. |
2004-04-09 |
2023-08-12 |
mouse |
| Yoshitoku Yoshida, Nagisa Matsumoto, Remi Tsuchiya, Mitsuhiro Morita, Hiroyoshi Miyakawa, Yoshihisa Kud. Expression of group I metabotropic glutamate receptors in rat hippocampal cells in culture and their characterization by intracellular calcium ion dynamics. Journal of pharmacological sciences. vol 92. issue 3. 2004-04-08. PMID:12890890. |
expression of group i metabotropic glutamate receptors in rat hippocampal cells in culture and their characterization by intracellular calcium ion dynamics. |
2004-04-08 |
2023-08-12 |
rat |
| Yoshitoku Yoshida, Nagisa Matsumoto, Remi Tsuchiya, Mitsuhiro Morita, Hiroyoshi Miyakawa, Yoshihisa Kud. Expression of group I metabotropic glutamate receptors in rat hippocampal cells in culture and their characterization by intracellular calcium ion dynamics. Journal of pharmacological sciences. vol 92. issue 3. 2004-04-08. PMID:12890890. |
the distribution of group i metabotropic glutamate receptors in rat hippocampal cells in culture was examined by calcium imaging and immunocytochemistry. |
2004-04-08 |
2023-08-12 |
rat |
| P Saransaari, S S Oj. Characterization of N-methyl-D-aspartate-evoked taurine release in the developing and adult mouse hippocampus. Amino acids. vol 24. issue 1-2. 2004-03-30. PMID:12624755. |
the ionotropic glutamate receptor agonist n-methyl-d-aspartate (nmda) greatly potentiates taurine release from brain preparations in both normal and ischemic conditions, the effect being particularly marked in the developing hippocampus. |
2004-03-30 |
2023-08-12 |
mouse |
| Ilse Smolders, Hilde Lindekens, Ralph Clinckers, Alfred Meurs, Michael J O'Neill, David Lodge, Guy Ebinger, Yvette Michott. In vivo modulation of extracellular hippocampal glutamate and GABA levels and limbic seizures by group I and II metabotropic glutamate receptor ligands. Journal of neurochemistry. vol 88. issue 5. 2004-03-30. PMID:15009663. |
in vivo modulation of extracellular hippocampal glutamate and gaba levels and limbic seizures by group i and ii metabotropic glutamate receptor ligands. |
2004-03-30 |
2023-08-12 |
rat |
| Ilse Smolders, Hilde Lindekens, Ralph Clinckers, Alfred Meurs, Michael J O'Neill, David Lodge, Guy Ebinger, Yvette Michott. In vivo modulation of extracellular hippocampal glutamate and GABA levels and limbic seizures by group I and II metabotropic glutamate receptor ligands. Journal of neurochemistry. vol 88. issue 5. 2004-03-30. PMID:15009663. |
the effects of several metabotropic receptor (mglur) ligands on baseline hippocampal glutamate and gaba overflow in conscious rats and the modulation of limbic seizure activity by these ligands were investigated. |
2004-03-30 |
2023-08-12 |
rat |
| Ilse Smolders, Hilde Lindekens, Ralph Clinckers, Alfred Meurs, Michael J O'Neill, David Lodge, Guy Ebinger, Yvette Michott. In vivo modulation of extracellular hippocampal glutamate and GABA levels and limbic seizures by group I and II metabotropic glutamate receptor ligands. Journal of neurochemistry. vol 88. issue 5. 2004-03-30. PMID:15009663. |
the mglu1a receptor antagonist ly367385 (1 mm) decreased baseline glutamate but not gaba concentrations, suggesting that mglu1a receptors, which regulate hippocampal glutamate levels, are tonically activated by endogenous glutamate. |
2004-03-30 |
2023-08-12 |
rat |
| Ilse Smolders, Hilde Lindekens, Ralph Clinckers, Alfred Meurs, Michael J O'Neill, David Lodge, Guy Ebinger, Yvette Michott. In vivo modulation of extracellular hippocampal glutamate and GABA levels and limbic seizures by group I and II metabotropic glutamate receptor ligands. Journal of neurochemistry. vol 88. issue 5. 2004-03-30. PMID:15009663. |
agonist-mediated actions at mglu2/3 receptors by ly379268 (100 microm, 10 mg/kg intraperitoneally) decreased basal hippocampal gaba but not glutamate levels. |
2004-03-30 |
2023-08-12 |
rat |
| Maricilia S Costa, João B T Rocha, Sandra R Perosa, Esper A Cavalheiro, Maria da Graça Naffah-Mazzacoratt. Pilocarpine-induced status epilepticus increases glutamate release in rat hippocampal synaptosomes. Neuroscience letters. vol 356. issue 1. 2004-03-29. PMID:14746897. |
pilocarpine-induced status epilepticus increases glutamate release in rat hippocampal synaptosomes. |
2004-03-29 |
2023-08-12 |
rat |
| Maricilia S Costa, João B T Rocha, Sandra R Perosa, Esper A Cavalheiro, Maria da Graça Naffah-Mazzacoratt. Pilocarpine-induced status epilepticus increases glutamate release in rat hippocampal synaptosomes. Neuroscience letters. vol 356. issue 1. 2004-03-29. PMID:14746897. |
we investigated the glutamate uptake and release by both cortical and hippocampal synaptosome in pilocarpine model of epilepsy. |
2004-03-29 |
2023-08-12 |
rat |