Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Pei-Yan Meng, Guo-Jie Sun, Sheng-Hong Liu, Hong-Mei Ya. [Effect of electroacupuncture pretreatment on glutamate-NMDAR signal pathway in hippocampal neurons of vascular dementia rats]. Zhen ci yan jiu = Acupuncture research. vol 33. issue 2. 2008-07-29. PMID:18630585. |
to observe the effect of electroacupuncture (ea) pretreatment on hippocampal glutamate (glu) content and n-methyl-d-aspartate receptor (nmdar)1 mrna expression in rats with vascular dementia (vd) so as to explore its underlying mechanism in improving vd. |
2008-07-29 |
2023-08-12 |
rat |
Miguel Salazar, José A Pariente, Ginés M Salido, Antonio Gonzále. Ethanol induces glutamate secretion by Ca2+ mobilization and ROS generation in rat hippocampal astrocytes. Neurochemistry international. vol 52. issue 6. 2008-07-28. PMID:18082912. |
ethanol induces glutamate secretion by ca2+ mobilization and ros generation in rat hippocampal astrocytes. |
2008-07-28 |
2023-08-12 |
rat |
Miguel Salazar, José A Pariente, Ginés M Salido, Antonio Gonzále. Ethanol induces glutamate secretion by Ca2+ mobilization and ROS generation in rat hippocampal astrocytes. Neurochemistry international. vol 52. issue 6. 2008-07-28. PMID:18082912. |
in this study we have investigated the effect of ethanol on [ca2+]c by microfluorimetry and glutamate secretion using an enzyme-linked system, in rat hippocampal astrocytes in culture. |
2008-07-28 |
2023-08-12 |
rat |
Miguel Salazar, José A Pariente, Ginés M Salido, Antonio Gonzále. Ethanol induces glutamate secretion by Ca2+ mobilization and ROS generation in rat hippocampal astrocytes. Neurochemistry international. vol 52. issue 6. 2008-07-28. PMID:18082912. |
in conclusion, our results suggest that ethanol mobilizes ca2+ from intracellular stores, and stimulates a ca2+-dependent glutamate secretion, probably involving reactive oxygen species production, and therefore creating a situation potentially leading to neurotoxicity in the hippocampus. |
2008-07-28 |
2023-08-12 |
rat |
Li Yang, Yasuhisa Nakayama, Naoki Hattori, Bing Liu, Chiyoko Inagak. GABAC-receptor stimulation activates cAMP-dependent protein kinase via A-kinase anchoring protein 220. Journal of pharmacological sciences. vol 106. issue 4. 2008-07-24. PMID:18385542. |
the present study showed that gaba(c)-receptor stimulation with its agonist, cis-4-aminocrotonic acid (caca), protected cultured hippocampal neurons from amyloid beta 25 - 35 (abeta25 - 35) peptide-enhanced glutamate neurotoxicity. |
2008-07-24 |
2023-08-12 |
rat |
Lidia Glodzik, Kevin G King, Oded Gonen, Songtao Liu, Susan De Santi, Mony J de Leo. Memantine decreases hippocampal glutamate levels: a magnetic resonance spectroscopy study. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 4. 2008-07-22. PMID:18343551. |
memantine decreases hippocampal glutamate levels: a magnetic resonance spectroscopy study. |
2008-07-22 |
2023-08-12 |
Not clear |
Lidia Glodzik, Kevin G King, Oded Gonen, Songtao Liu, Susan De Santi, Mony J de Leo. Memantine decreases hippocampal glutamate levels: a magnetic resonance spectroscopy study. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 4. 2008-07-22. PMID:18343551. |
memantine reduced hippocampal glutamate levels, which may be consistent with its anti-excitotoxic property. |
2008-07-22 |
2023-08-12 |
Not clear |
Ilse Smolders, Ralph Clinckers, Alfred Meurs, Dimitri De Bundel, Jeanelle Portelli, Guy Ebinger, Yvette Michott. Direct enhancement of hippocampal dopamine or serotonin levels as a pharmacodynamic measure of combined antidepressant-anticonvulsant action. Neuropharmacology. vol 54. issue 6. 2008-07-22. PMID:18378264. |
since glutamate-mediated hyperexcitability in temporal lobe regions seems to be involved in disturbed emotional behaviour, we next investigated possible antidepressant effects and hippocampal da or 5-ht modulations exerted by selective ionotropic and metabotropic glutamate receptor ligands with anticonvulsant properties. |
2008-07-22 |
2023-08-12 |
mouse |
Jens P Bankstahl, Katrin Hoffmann, Kerstin Bethmann, W Lösche. Glutamate is critically involved in seizure-induced overexpression of P-glycoprotein in the brain. Neuropharmacology. vol 54. issue 6. 2008-07-22. PMID:18394657. |
furthermore, neurodegeneration developing in the hippocampus and parahippocampal regions was reduced by the glutamate antagonist. |
2008-07-22 |
2023-08-12 |
rat |
O Khongsombat, H Watanabe, B Tantisira, C Patarapanich, M H Tantisir. Acute effects of N-(2-propylpentanoyl)urea on hippocampal amino acid neurotransmitters in pilocarpine-induced seizure in rats. Epilepsy research. vol 79. issue 2-3. 2008-07-22. PMID:18439803. |
the present study aimed to investigate the anticonvulsant activity as well as the effects on the level of hippocampal amino acid neurotransmitters (glutamate, aspartate, glycine and gaba) of n-(2-propylpentanoyl)urea (vpu) in comparison to its parent compound, valproic acid (vpa). |
2008-07-22 |
2023-08-12 |
rat |
O Khongsombat, H Watanabe, B Tantisira, C Patarapanich, M H Tantisir. Acute effects of N-(2-propylpentanoyl)urea on hippocampal amino acid neurotransmitters in pilocarpine-induced seizure in rats. Epilepsy research. vol 79. issue 2-3. 2008-07-22. PMID:18439803. |
in vivo microdialysis demonstrated that an intraperitoneal administration of pilocarpine induced a pronounced increment of hippocampal glutamate and aspartate whereas no significant change was observed on the level of glycine and gaba. |
2008-07-22 |
2023-08-12 |
rat |
Fleur Margaret Howells, Vivienne Ann Russel. Glutamate-stimulated release of norepinephrine in hippocampal slices of animal models of attention-deficit/hyperactivity disorder (spontaneously hypertensive rat) and depression/anxiety-like behaviours (Wistar-Kyoto rat). Brain research. vol 1200. 2008-07-18. PMID:18295191. |
the present study was undertaken to determine the differential effects of glutamate on norepinephrine release in hippocampal slices of several rat strains. |
2008-07-18 |
2023-08-12 |
rat |
Fleur Margaret Howells, Vivienne Ann Russel. Glutamate-stimulated release of norepinephrine in hippocampal slices of animal models of attention-deficit/hyperactivity disorder (spontaneously hypertensive rat) and depression/anxiety-like behaviours (Wistar-Kyoto rat). Brain research. vol 1200. 2008-07-18. PMID:18295191. |
(3) exposure of hippocampal slices to a second and third 1-min pulse of glutamate revealed significant decreases in the peaks of [(3)h]norepinephrine release suggesting internalization of ampa receptors. |
2008-07-18 |
2023-08-12 |
rat |
Luis F Pacheco Otalora, Eder F Hernandez, Massoud F Arshadmansab, Sebastian Francisco, Michael Willis, Boris Ermolinsky, Masoud Zarei, Hans-Guenther Knaus, Emilio R Garrido-Sanabri. Down-regulation of BK channel expression in the pilocarpine model of temporal lobe epilepsy. Brain research. vol 1200. 2008-07-18. PMID:18295190. |
in the hippocampus, bk channels are preferentially localized in presynaptic glutamatergic terminals including mossy fibers where they are thought to play an important role regulating excessive glutamate release during hyperactive states. |
2008-07-18 |
2023-08-12 |
rat |
Clotilde Lauro, Silvia Di Angelantonio, Raffaela Cipriani, Fabrizia Sobrero, Letizia Antonilli, Valentina Brusadin, Davide Ragozzino, Cristina Limatol. Activity of adenosine receptors type 1 Is required for CX3CL1-mediated neuroprotection and neuromodulation in hippocampal neurons. Journal of immunology (Baltimore, Md. : 1950). vol 180. issue 11. 2008-07-18. PMID:18490761. |
through the activation of its own specific receptor, cx(3)cr1, cx(3)cl1 exerts both neuroprotection against glutamate (glu) toxicity and neuromodulation of the glutamatergic synaptic transmission in hippocampal neurons. |
2008-07-18 |
2023-08-12 |
mouse |
Francis Chaouloff, Agnès Hémar, Olivier Manzon. Local facilitation of hippocampal metabotropic glutamate receptor-dependent long-term depression by corticosterone and dexamethasone. Psychoneuroendocrinology. vol 33. issue 5. 2008-07-08. PMID:18321654. |
local facilitation of hippocampal metabotropic glutamate receptor-dependent long-term depression by corticosterone and dexamethasone. |
2008-07-08 |
2023-08-12 |
rat |
José Antonio López-Moreno, Gustavo González-Cuevas, Guillermo Moreno, Miguel Navarr. The pharmacology of the endocannabinoid system: functional and structural interactions with other neurotransmitter systems and their repercussions in behavioral addiction. Addiction biology. vol 13. issue 2. 2008-07-08. PMID:18422831. |
moreover, the neurotransmitter with the fewest number of related studies is acetylcholine (excepting in the hippocampus), whereas there is a large number that evaluates gaba, glutamate and dopamine. |
2008-07-08 |
2023-08-12 |
Not clear |
C J Peddie, H A Davies, F M Colyer, M G Stewart, J J Rodrígue. Colocalisation of serotonin2A receptors with the glutamate receptor subunits NR1 and GluR2 in the dentate gyrus: an ultrastructural study of a modulatory role. Experimental neurology. vol 211. issue 2. 2008-07-07. PMID:18439999. |
the serotonin(2a) receptor (5-ht(2a)r) is implicated in many neurological disorders and has a role in cognitive processes, reliant upon hippocampal glutamate receptors. |
2008-07-07 |
2023-08-12 |
Not clear |
C J Peddie, H A Davies, F M Colyer, M G Stewart, J J Rodrígue. Colocalisation of serotonin2A receptors with the glutamate receptor subunits NR1 and GluR2 in the dentate gyrus: an ultrastructural study of a modulatory role. Experimental neurology. vol 211. issue 2. 2008-07-07. PMID:18439999. |
here, we have conducted an electron microscopic examination of 5-ht(2a)r distribution with the glutamate n-methyl-d-aspartate (nmda) and amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid (ampa) receptor subunits nr1 and glur2 in the hippocampal dentate gyrus (dg) in order to investigate whether 5-ht(2a)r location is compatible with a modulatory role over nmda and/or ampa receptor mediated neurotransmission. |
2008-07-07 |
2023-08-12 |
Not clear |
Tao Song, Naoya Hatano, Toshie Kambe, Yoshiaki Miyamoto, Hideshi Ihara, Hideyuki Yamamoto, Katsuyoshi Sugimoto, Kodai Kume, Fuminori Yamaguchi, Masaaki Tokuda, Yasuo Watanab. Nitric oxide-mediated modulation of calcium/calmodulin-dependent protein kinase II. The Biochemical journal. vol 412. issue 2. 2008-07-03. PMID:18271754. |
in addition, treatment with glutamate caused an increase in camkii s-nitrosylation in rat hippocampal slices. |
2008-07-03 |
2023-08-12 |
rat |